Significance of palliative gastrectomy for late-stage gastric cancer patients.

Abstract:

PURPOSE:To investigate the significance of palliative gastrectomy for different types of metastatic gastric cancer patients displaying peritoneal dissemination, hepatic metastasis, distant lymph node metastasis occurring locally during late-stage disease, and multi-organ metastases. METHODS:We performed a retrospective study of 862 patients who were histologically diagnosed as late-stage gastric cancer who could not undergo radical surgery at the Sun Yat-sen University Cancer Center between January 1993 and December 2008. The follow-up lasted until December 2010. Chi-square tests and Kaplan-Meier methods were employed to compare the adverse events and prognoses. RESULTS:In the peritoneal dissemination and multi-organ metastases groups, palliative gastrectomy has no survival benefit (P = 0.705, 0.331, respectively). In the patients with distant lymph-node metastases, liver metastasis and locally late-stage gastric cancer patients, palliative gastrectomy was a prognostic factor (P < 0.001, P < 0.001, P = 0.010, respectively). Multivariable analysis demonstrated that palliative gastrectomy was an independent prognostic factor for distant lymph-node metastases, liver metastasis, and local late-stage gastric cancer patients. Palliative gastrectomy combined with hepatectomy proved to be an independent prognostic factor to improve the overall survival of patients with liver metastases who underwent palliative gastrectomy (P = 0.008). CONCLUSION:For late-stage gastric cancer patients, palliative gastrectomy should be considered for locally late-stage, distant lymph node metastasis, and resectable liver metastasis patients. Especially among patients with liver metastasis, transfer medicine is essential for potentially curable patients to obtain access to radical surgery to improve the prognosis.

journal_name

J Surg Oncol

authors

Chen S,Li YF,Feng XY,Zhou ZW,Yuan XH,Chen YB

doi

10.1002/jso.23158

subject

Has Abstract

pub_date

2012-12-01 00:00:00

pages

862-71

issue

7

eissn

0022-4790

issn

1096-9098

journal_volume

106

pub_type

杂志文章
  • Experimental study and clinical application of a single-row suturing esophagogastrostomy.

    abstract::A single-row suturing anastomosis (SRA) for an esophagogastrostomy was experimentally investigated in dogs. SRA not only shortened operating time, but also led to better pathological results when compared with double-row suturing anastomosis. Wide-brim suturing and equal distance between the sutures, providing increas...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930430309

    authors: Gao SZ,Wang TS,Yao Z,Cheng BC,Tu ZF,Ling DM,Peng SY

    更新日期:1990-03-01 00:00:00

  • Proposal for anatomical classification of the superior pole in thyroid surgery.

    abstract:OBJECTIVE:To propose a distinct anatomical classification for the superior thyroid pole that may serve as a surgical landmark and could help reduce complications in thyroid surgery. MATERIALS AND METHODS:A comprehensive anatomical study based on existing literature and surgical observations. RESULTS:The proposed supe...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.23950

    authors: Mizrachi A,Swartzwelder CE,Shaha AR

    更新日期:2015-07-01 00:00:00

  • The peak-standardized uptake value (P-SUV) by preoperative positron emission tomography-computed tomography (PET-CT) is a useful indicator of lymph node metastasis in gastric cancer.

    abstract:BACKGROUND AND OBJECTIVES:Little data is currently available on the usefulness of peak-standardized uptake value (P-SUV) by positron emission tomography-computed tomography (PET-CT) in gastric cancer. The purpose of the present study was to evaluate the value of PET-CT for the preoperative evaluation of patients with g...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.21985

    authors: Oh HH,Lee SE,Choi IS,Choi WJ,Yoon DS,Min HS,Ra YM,Moon JI,Kang YH

    更新日期:2011-10-01 00:00:00

  • Munchausen's syndrome and cancer.

    abstract::Munchausen's syndrome is a chronic factitious disorder characterized by frequent hospitalizations, self-inflicted injuries, and dramatic medical histories. People with this condition assume the role of a sick patient and submit to unnecessary invasive, painful, and even dangerous medical procedures. In review of the l...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.2930560219

    authors: Bruns AD,Fishkin PA,Johnson EA,Lee YT

    更新日期:1994-06-01 00:00:00

  • Extended right hepatectomy with caudate lobe resection using the hilar "en bloc" resection technique with a modified hanging maneuver.

    abstract::The hanging liver maneuver is a useful technique to guide the transection of liver parenchyma by lifting a tape passed between the anterior surface of the inferior vena cava and the liver. Modified hanging liver maneuvers have been described in different types of liver resection. Surgical resection of hilar cholangioc...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.24154

    authors: Perini MV,Coelho FF,Kruger JA,Rocha FG,Herman P

    更新日期:2016-03-01 00:00:00

  • Adenocarcinoma of the lung: clinicopathological study.

    abstract::A review of our 247 patients with adenocarcinoma of the lung revealed the overall five year survival rate to be only 0.81%. Lung resection offers the chance of cure if the lesion is peripherally located and without lymph node involvement. Direct chest wall invasion by tumor is not contraindication to surgery. Radiatio...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930070306

    authors: Marabella P,Takita H

    更新日期:1975-01-01 00:00:00

  • Pharmacokinetics of cis-diamminedichloroplatinum (II) given as low-dose and high-dose infusions.

    abstract::A pharmacokinetic analysis of cis-diamminedichloroplatinum (II) (DDP) was conducted comparing low-dose daily bolus infusions, and high-dose drip infusions. Eight patients with gastric cancer were treated with low-dose daily bolus infusions of DDP to a total daily dose of 75 mg/m2 bid for 5 days. Four patients with eso...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/(SICI)1096-9098(199606)62:2<135::AID-JSO10

    authors: Kurihara N,Kubota T,Hoshiya Y,Otani Y,Ando N,Kumai K,Kitajima M

    更新日期:1996-06-01 00:00:00

  • Gastric cancer: biology and clinical manifestations in Israel.

    abstract:BACKGROUND:Gastric cancer (GC) in Israel remains incompletely characterized. The aim of this study was to define the clinical and pathological characteristics of GC in Israel and to compare them to the general Western population. PATIENTS AND METHODS:This is a retrospective analysis of 461 consecutive GC patients trea...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.22078

    authors: Dreznik A,Purim O,Idelevich E,Kundel Y,Sulkes J,Sulkes A,Brenner B

    更新日期:2012-03-01 00:00:00

  • Unusual origins of Pseudomyxoma peritonei.

    abstract::Pseudomyxoma peritonei is a rare neoplastic condition in that gelatinous intraperitoneal fluid collections and mucinous implants on the peritoneal surfaces and omentum are found. The pathological origin is usually an adenoma or well-differentiated adenocarcinoma of the appendix. A smaller number of cases arises from o...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/1096-9098(200012)75:4<270::aid-jso9>3.0.co

    authors: de Bree E,Witkamp A,Van De Vijver M,Zoetmulde F

    更新日期:2000-12-01 00:00:00

  • Impact of delayed care on surgical management of patients with gastric cancer in a low-resource setting.

    abstract:BACKGROUND:Gastric cancer is the fifth most common cancer in Eastern Africa. Diagnostic delays in low-resource countries result in advanced disease presentation. We describe perioperative management of gastric cancer in Rwanda. METHODS:A retrospective review of records at three hospitals was performed to identify gast...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,多中心研究

    doi:10.1002/jso.25286

    authors: Martin AN,Silverstein A,Ssebuufu R,Lule J,Mugenzi P,Fehr A,Mpunga T,Shulman LN,Park PH,Costas-Chavarri A

    更新日期:2018-12-01 00:00:00

  • A novel preoperative risk score to predict lymph node positivity for rectal neuroendocrine tumors: An NCDB analysis to guide operative technique.

    abstract:BACKGROUND/OBJECTIVE:Staging and type of resection for rectal neuroendocrine tumors (R-NETS) relies on preoperative identification of lymph node (LN) involvement. Study objective was to develop a Preoperative Rectal Stratification Score (PReSS) for LN-positivity and to assess the association of PReSS with overall survi...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.25679

    authors: Gamboa AC,Liu Y,Lee RM,Zaidi MY,Staley CA,Russell MC,Cardona K,Sullivan PS,Maithel SK

    更新日期:2019-11-01 00:00:00

  • Post-mastectomy radiation therapy and overall survival after neoadjuvant chemotherapy.

    abstract:BACKGROUND:The role of postmastectomy radiation therapy (PMRT) after neoadjuvant chemotherapy (NAC) and mastectomy is unclear, especially in patients that have post-treatment tumor negative axillary nodes (ypN0). METHODS:The National Cancer Data Base was used to identify women that had PMRT after NAC and mastectomy fo...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.24551

    authors: Kantor O,Pesce C,Singh P,Miller M,Tseng J,Wang CH,Winchester DJ,Yao K

    更新日期:2017-05-01 00:00:00

  • Historical perspectives and future directions in the surgical management of retroperitoneal sarcoma.

    abstract::Retroperitoneal sarcomas (RPS) have fascinated and intrigued physicians both past and present. Operative mortality rates were historically very high and complete resection was not possible for the majority of patients until only the last 2 decades. More recently, changes to the surgical approach and clinical decision-...

    journal_title:Journal of surgical oncology

    pub_type: 历史文章,杂志文章,评审

    doi:10.1002/jso.24888

    authors: Tseng WW,Seo HJ,Pollock RE,Gronchi A

    更新日期:2018-01-01 00:00:00

  • Tumor differentiation and histological type in human breast cancer.

    abstract::Biopsies from 61 women with breast cancer were assessed for various histological features. These results were statistically analyzed for associations of gross tumor size, patient age, stage of disease, tumor hormone receptor status, with accepted systems of nuclear and histological grading for differentiation. Tumors ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930310109

    authors: Bell CD,Stadler J,Waizbard E,Chaitchik S,Greif F

    更新日期:1986-01-01 00:00:00

  • Serological evaluation of human brain tumors using a microradioisotopic staphylococcal protein A assay.

    abstract::A microradioisotopic staphylococcal protein A assay was applied to the serological evaluation of preoperative sera from brain tumor patients. The assay was performed in Terasaki plates, and a stainless steel punch and multiholed die facilitated sample prearation. Using allogeneic astrocytoma target cells, 15/19 of the...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930140306

    authors: Cohen AM,Wood WC

    更新日期:1980-01-01 00:00:00

  • Frequent K-ras mutations and absence of p53 mutations in mucin-producing tumors of the pancreas.

    abstract::Mucin-producing tumors of the pancreas (MPT) are characterized by the production of much mucin and a benign course after surgical treatment. We examined 16 cases of MPT and 20 cases of "common" pancreatic duct cell carcinomas (DCC) in regard to K-ras and p53 mutations. The mutations were detected by constant denaturan...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930550205

    authors: Hoshi T,Imai M,Ogawa K

    更新日期:1994-02-01 00:00:00

  • Submental flap for vascularized lymph node transfer; a CTA-based study on lymph node distribution.

    abstract:BACKGROUND:Amongst various options of vascularized lymph node transfers, the submental flap has the lowest risk for iatrogenic lymphedema. The aim of this study was to gain insight into distribution, number, and size of lymph nodes along the mandible using computed tomography angiography (CTA). METHODS:A total of 52 C...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.26117

    authors: Paulus VAA,Winters H,Hummelink S,Schulten S,Ulrich DJO,Vasilic D

    更新日期:2020-07-15 00:00:00

  • Yttrium-90 radiation segmentectomy for hepatic metastases: A multi-institutional study of safety and efficacy.

    abstract:BACKGROUND AND OBJECTIVES:This study assessed the outcomes of Yttrium-90 (90 Y) radiation segmentectomy for hepatic metastases unamenable to resection or ablation. MATERIALS AND METHODS:Over 6 years, 36 patients with 53 tumors underwent segmental radioembolization. Patients were not candidates for surgical resection o...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,多中心研究

    doi:10.1002/jso.26223

    authors: Padia SA,Johnson GE,Agopian VG,DiNorcia J,Srinivasa RN,Sayre J,Shin DS

    更新日期:2021-01-01 00:00:00

  • Prognostic utility of albumin-bilirubin grade for short- and long-term outcomes following hepatic resection for intrahepatic cholangiocarcinoma: A multi-institutional analysis of 706 patients.

    abstract:BACKGROUND:The objective of the current study was to define the impact of albumin-bilirubin (ALBI) grade on short- as well as long-term outcomes among patients with intrahepatic cholangiocarcinoma (ICC). METHODS:Patients who underwent hepatectomy for ICC between 1990 and 2016 were identified using an international mul...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,多中心研究

    doi:10.1002/jso.25486

    authors: Tsilimigras DI,Hyer JM,Moris D,Sahara K,Bagante F,Guglielmi A,Aldrighetti L,Alexandrescu S,Marques HP,Shen F,Koerkamp BG,Endo I,Pawlik TM,other members of the International Intrahepatic Cholangiocarcinoma Study Group.

    更新日期:2019-08-01 00:00:00

  • Implication of telomere length as a proliferation-associated marker in schwannomas.

    abstract:BACKGROUND AND OBJECTIVES:Some schwannomas in the central nervous system may demonstrate relatively aggressive behavior in pathological findings and clinical course. We evaluate the diagnostic values of telomerase activity and telomere length in the clinicopathological behavior of schwannomas. METHODS:Thirty surgical ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.10139

    authors: Chen HJ,Cho CL,Liang CL,Lu K,Lin JW

    更新日期:2002-10-01 00:00:00

  • Performance of prognostic scores and staging systems in predicting long-term survival outcomes after surgery for intrahepatic cholangiocarcinoma.

    abstract:INTRODUCTION:We sought to validate the commonly used prognostic models and staging systems for intrahepatic cholangiocarcinoma (ICC) in a large multi-center patient cohort. METHODS:The overall (OS) and disease free survival (DFS) prognostic discriminatory ability of various commonly used models were assessed in a larg...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.24759

    authors: Buettner S,Galjart B,van Vugt JLA,Bagante F,Alexandrescu S,Marques HP,Lamelas J,Aldrighetti L,Gamblin TC,Maithel SK,Pulitano C,Margonis GA,Weiss M,Bauer TW,Shen F,Poultsides GA,Marsh JW,IJzermans JNM,Groot Koerkamp B

    更新日期:2017-12-01 00:00:00

  • Comparative analysis of imaging modalities in the preoperative assessment of nodal metastasis in esophageal cancer.

    abstract::Preoperative radiological findings of nodal status in 74 patients, using endoscopic ultrasonography (EUS), computed tomography (CT), ultrasonography (US), and magnetic resonance imaging (MRI), were compared to histopathology reports following transthoracic total esophagectomy with radical lymphadenectomy (TTE), involv...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/(SICI)1096-9098(199603)61:3<214::AID-JSO10

    authors: Chandawarkar RY,Kakegawa T,Fujita H,Yamana H,Hayabuthi N

    更新日期:1996-03-01 00:00:00

  • ERCP in potentially resectable malignant biliary obstruction is frequently unsuccessful when performed outside of a comprehensive pancreaticobiliary center.

    abstract:BACKGROUND AND OBJECTIVES:ERCP prior to pancreaticoduodenectomy is unnecessary in select patients. When performed, it should be in conjunction with endoscopic ultrasound (EUS) to increase diagnostic sensitivity and allow for metal stent placement. The aim of this study was to determine differences in endoscopic practic...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.24191

    authors: Donnan E,Bentrem DJ,Komanduri S,Mahvi DM,Keswani RN

    更新日期:2016-05-01 00:00:00

  • A single blinded randomized controlled trial comparing semi-mechanical with hand-sewn cervical anastomosis after esophagectomy for cancer (SHARE-study).

    abstract:OBJECTIVE:The aim was to compare leak rate between hand-sewn end-to-end anastomosis (ETE) and semi-mechanical anastomosis (SMA) after esophagectomy with gastric tube reconstruction. BACKGROUND DATA:The optimal surgical technique for creation of an anastomosis in the neck after esophagectomy is unclear. METHODS:Patien...

    journal_title:Journal of surgical oncology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/jso.26209

    authors: Nederlof N,Tilanus HW,de Vringer T,van Lanschot JJB,Willemsen SP,Hop WCJ,Wijnhoven BPL

    更新日期:2020-12-01 00:00:00

  • Elective neck dissection (END) and cN0 hard palate and upper gingival cancers: A National Cancer Database analysis of factors predictive of END and impact on survival.

    abstract:BACKGROUND AND OBJECTIVES:The reported risk of nodal metastasis in hard palate and upper gingival squamous cell carcinoma (SCC) has been inconsistent with inadequate consensus regarding the utility of neck dissection in the clinically negative (cN0) neck. MATERIALS AND METHODS:Using the National Cancer Database, cN0 p...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.25706

    authors: Obayemi A Jr,Cracchiolo JR,Migliacci JC,Husain Q,Rahmati R,Roman BR,Cohen MA

    更新日期:2019-12-01 00:00:00

  • Comparison of R1 and R2 gastrectomy for gastric cancer in patients over 80 years of age.

    abstract::To evaluate the benefit of R2 gastrectomy for gastric cancer in Japanese patients over 80 years of age, data on 93 patients who underwent gastrectomy between 1967 and 1989 were collected retrospectively from charts filed in the Kyushu University Hospital and two affiliated national hospitals. Of 93 patients, 62 had a ...

    journal_title:Journal of surgical oncology

    pub_type: 临床试验,杂志文章

    doi:10.1002/jso.2930480213

    authors: Korenaga D,Baba H,Kakeji Y,Orita H,Haraguchi M,Maehara Y,Saku M,Sugimachi K

    更新日期:1991-10-01 00:00:00

  • New intraoperative brachytherapy techniques for positive or close surgical margins.

    abstract::Tumors attached or adjacent to critical structures can often not be completely resected or resected with adequate surgical margins. Sites involving major blood vessels, the paravertebral spaces, or critical abdominal structures often present technical difficulties for standard brachytherapy procedures using I-125 or I...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930420112

    authors: Nori D,Bains M,Hilaris BS,Harrison L,Fass D,Peretz T,Donath D,Fuks Z

    更新日期:1989-09-01 00:00:00

  • Consensus statement on peritoneal mesothelioma.

    abstract::Diffuse malignant peritoneal mesothelioma (DMPM) has been traditionally regarded as a rapidly lethal disease. Recently, several independent prospective trials have reported improved survival with an intensive loco-regional treatment strategy including cytoreductive surgery (CRS) along with peri-operative intra-periton...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.21055

    authors: Deraco M,Bartlett D,Kusamura S,Baratti D

    更新日期:2008-09-15 00:00:00

  • Brain, the last fortress of sarcoma: similar dismal outcome but discrepancy of timing of brain metastasis in bone and soft tissue sarcoma.

    abstract:BACKGROUND AND OBJECTIVE:Brain metastasis is a rare but dismal event in sarcomas. However, the pattern of occurrence and the prognostic factors associated with post-brain metastasis survival (PBMS) are not yet well-characterized. METHODS:Sarcoma patients treated at one institute within 10-year period were retrospectiv...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.22011

    authors: Chou YS,Liu CY,Chen WM,Chen TH,Chen PC,Wu HT,Shiau CY,Wu YC,Liu CL,Chao TC,Tzeng CH,Wong TT,Yen CC

    更新日期:2011-12-01 00:00:00

  • Isolated limb perfusion in Merkel cell carcinoma offers high rate of complete response and durable local-regional control: Systematic review and institutional experience.

    abstract:INTRODUCTION:Hyperthermic isolated limb perfusion (HILP) has an established role in the management of melanoma, but its role for Merkel cell carcinoma (MCC) is less well defined. METHODS:Retrospective review of our institutional experience with HILP for MCC was conducted (2009-2015). Literature search was performed th...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.24289

    authors: Thiels CA,Gonzalez AB,Gray RJ,Jakub JW

    更新日期:2016-08-01 00:00:00