Initiation of adjuvant therapy following surgical resection of pancreatic ductal adenocarcinoma (PDAC): Are patients from rural, remote areas disadvantaged?

abstract：BACKGROUND:In the United States, pulmonary adenocarcinomas have recently replaced squamous cell carcinomas as the most frequent type of lung cancer encountered. The incidence of pulmonary adenocarcinoma continued to increase worldwide. METHOD:To determine the roles of the transforming growth factor-beta 1 (TGF-beta 1)...

journal_title：Journal of surgical oncology

authors： Takanami I,Tanaka F,Hashizume T,Kodaira S

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Small lung adenocarcinomas are detected more frequently than in the past. However, the clinicopathologic characteristics and prognostic significance of EGFR/p53 mutations in these tumors remains unclear. METHODS:We evaluated the correlation of EGFR/p53 mutations with clinicopathologic charact...

journal_title：Journal of surgical oncology

authors： Lin MW,Wu CT,Shih JY,Chang YL,Yang PC

更新日期：2014-08-01 00:00:00

abstract：:Up to 50% of patients with colorectal cancer will develop metastatic disease in the liver. While surgical extirpation remains the best option for long-term survival, several complementary modalities such as laparoscopy, radiofrequency ablation, and microwave coagulation have gained wide acceptance as primary and adjun...

journal_title：Journal of surgical oncology

authors： Rocha FG,D'Angelica M

更新日期：2010-12-15 00:00:00

abstract：:Intrahepatic cholangiocarcinoma (iCCA) is the second most common primary hepatic cancer in the United States. Currently, curative treatment involves aggressive surgery. Chemotherapy and radiation treatments have been used for unresectable tumors with some success. Optimizing the use of current and developing novel mul...

journal_title：Journal of surgical oncology

authors： Simo KA,Halpin LE,McBrier NM,Hessey JA,Baker E,Ross S,Swan RZ,Iannitti DA,Martinie JB

更新日期：2016-01-01 00:00:00

abstract：:A review of our 247 patients with adenocarcinoma of the lung revealed the overall five year survival rate to be only 0.81%. Lung resection offers the chance of cure if the lesion is peripherally located and without lymph node involvement. Direct chest wall invasion by tumor is not contraindication to surgery. Radiatio...

journal_title：Journal of surgical oncology

authors： Marabella P,Takita H

更新日期：1975-01-01 00:00:00

abstract：:The T N M staging system created by a surgeon in the 1950s continues to be a major benchmark for assessing long-term outcomes in adult solid tumors. Although several major changes have occurred in this anatomical staging system, the tenets of TNM staging remain constant. Recently molecular markers and biologic modifie...

journal_title：Journal of surgical oncology

authors： Greene FL

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:An increasing proportion of patients are presenting with colorectal cancer at an early age. A proportion of these occur with genetic syndromes; however the majority present as sporadic. The purpose of this study is to investigate the prognosis and treatment of young patients with sporadic metastatic colorect...

journal_title：Journal of surgical oncology

authors： Smith JD,Lowery MA,Fell D,Gallagher DJ,Nash GM,Kemeny NE

更新日期：2016-04-01 00:00:00

abstract：:Five patients with breast cancer and malignant melanoma are reported. Two patients had a third primary malignancy. In 4 out of 5 patients the breast tumor was the initial tumor discovered, and in 4 out of 5 the second tumor evolved metachronously. No specific carcinogenic factor could be established. The low malignanc...

journal_title：Journal of surgical oncology

authors： Lokich JJ

更新日期：1975-01-01 00:00:00

abstract：:During the years 1975-1988, twenty lung cancer patients with symptomatic pericardial effusion were treated conservatively at our center. Echocardiography demonstrated small pericardial effusion in 2 patients, medium size effusion in 3 patients and large amount of fluid in 15 patients. Fifteen patients developed cardia...

journal_title：Journal of surgical oncology

authors： Edoute Y,Malberger E,Kuten A,Moscovitcz M,Ben-Haim SA

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:MicroRNAs (miRNAs) are small, noncoding RNAs that are involved in carcinogenesis through postranscriptional gene regulatory activity. Few studies have focused on the detection of miR-21 in serum rather than in tissue. The current study aimed to measure serum miR-21 expression levels and to eva...

journal_title：Journal of surgical oncology

authors： Menéndez P,Padilla D,Villarejo P,Palomino T,Nieto P,Menéndez JM,Rodríguez-Montes JA

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVES:To investigate predictors of occult nipple-areolar complex (NAC) involvement in patients with carcinoma in situ (CIS) and to validate an online probability calculator (CancerMath; www.lifemath.net/cancer/breastcancer/nipplecalc/index.php). METHODS:Mastectomized patients with CIS (n = 104) were retrospective...

journal_title：Journal of surgical oncology

authors： Hwang H,Park S,Koo JS,Park HS,Kim SI,Cho YU,Park BW,Yoon JH,Kim MJ,Kim EK

更新日期：2017-12-01 00:00:00

abstract：:Of 134 patients with thymoma, 79 (59%) also had myasthenia gravis (MG). The thymoma with MG differed from that in the absence of MG in the following aspects: The ratio of lymphocytes to epithelial cells in the tumor was larger, the polygonal cell type was more prominent (i.e., in 83% of the MG patients this cell type ...

journal_title：Journal of surgical oncology

authors： Monden Y,Uyama T,Taniki T,Hashimoto J,Fujii Y,Nakahara K,Kawashima Y,Masaoka A

更新日期：1988-07-01 00:00:00

abstract：:Between January 1, 1968 and December 31, 1978, 42 patients with malignant lesions involving the major salivary glands were seen at the Medical College of Virginia. A 60% 2-year survival and a 42% 5-year survival were noted. Histologic type was the major determinant of survival. Symptoms other than a painless mass, a l...

journal_title：Journal of surgical oncology

authors： Lawrence WT,Lawrence W Jr

更新日期：1981-01-01 00:00:00

abstract：:A patient with squamous cell carcinoma of the esophagus developed fatal aortoesophageal (AE) fistula following a preoperative course of combined chemotherapy plus radiation therapy. This is the first reported case of AE fistula following preoperative chemoradiotherapy. This complication is potentially correctable if s...

journal_title：Journal of surgical oncology

authors： Gabrail NY,Harrison BR,Sunwoo YC

更新日期：1991-11-01 00:00:00

abstract：PURPOSE:The aim of this study was to determine which clinicopathological factors influenced the long-term survival after potentially curative resection of patients with colon cancer having fewer than 12 retrieved lymph nodes. METHODS:Prospective data were collected from 179 patients who had fewer than 12 resected lymp...

journal_title：Journal of surgical oncology

authors： Huh JW,Kim CH,Kim HR,Kim YJ

更新日期：2012-02-01 00:00:00

abstract：:Depending on the local extension of primary non-small cell lung cancer (NSCLC) and invaded T4 structure(s), 49 patients underwent complete (CR, n = 14) or palliative (PR, n = 13) resection of exploratory thoracotomy (ET, n = 22) between January 1982 and June 1988. Thoracic radiotherapy (TR) was given to all patients r...

journal_title：Journal of surgical oncology

authors： Macchiarini P,Silvano G,Janni A,Mussi A,Chella A,Angeletti CA

更新日期：1991-08-01 00:00:00

abstract：:Interleukin-2 and hyperthermia have been used individually to treat a variety of tumors in both experimental and human trials. Combined adoptive immunotherapy and hyperthermia is an exciting new line of investigation. Previous work in our laboratory has shown that combined local hyperthermia and rIL-2 therapy can sign...

journal_title：Journal of surgical oncology

authors： Geehan DM,Fabian DF,Lefor AT

更新日期：1993-07-01 00:00:00

abstract：:A retrospective study was made of 38 myosarcomas of the small and large intestines (34 leiomyosarcomas and 4 malignant leiomyoblastomas). Endoenteric, small, and noninvasive tumors were successfully treated by simple wedge excision, cautery snare removal, or segmental bowel resection with a high 5-yr cure rate of 86% ...

journal_title：Journal of surgical oncology

authors： Shiu MH,Farr GH,Egeli RA,Quan SH,Hajdu SI

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Reports of clinicopathological features and prognosis in patients with mucinous gastric carcinoma (MGC) are conflicting. The aim was to describe the clinicopathological features and prognosis of patients with MGC in comparison with nonmucinous gastric carcinoma (NMGC). METHODS:We reviewed the...

journal_title：Journal of surgical oncology

authors： Zhang M,Zhu GY,Zhang HF,Gao HY,Han XF,Xue YW

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Only a few surgeons with much experience of laparoscopic surgery perform laparoscopy-assisted total gastrectomy (LATG), because of its technical difficulty and concern about subsequent complications. The aim of this study was to evaluate the technical feasibility and safety of LATG as compared ...

journal_title：Journal of surgical oncology

authors： Lee SE,Ryu KW,Nam BH,Lee JH,Kim YW,Yu JS,Cho SJ,Lee JY,Kim CG,Choi IJ,Kook MC,Park SR,Kim MJ,Lee JS

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Prone extralevator abdominoperineal excision of the rectum (ELAPE) has been introduced to improve the circumferential resection margins (CRM) compared with traditional APER. OBJECTIVE:We present short-term results achieved with prone ELAPE preceded by neoadjuvant chemoradiotherapy during the last 5 years of...

journal_title：Journal of surgical oncology

authors： Gravante G,Miah A,Mann CD,Stephenson JA,Gani MA,Sharpe D,Norwood M,Boyle K,Miller A,Hemingway D

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Neoadjuvant chemotherapy (nCMT) has been increasingly used in advanced gastric cancer (GC). However, the prognostic impact of tumor response remains unclear. This study aimed to evaluate if tumor response at the primary site and lymph nodes (LN) correlate with survival in GC patients after nCMT...

journal_title：Journal of surgical oncology

authors： Pereira MA,Ramos MFKP,Dias AR,Cardili L,Ribeiro RRE,Charruf AZ,de Castria TB,Zilberstein B,Ceconello I,Avancini Ferreira Alves V,Ribeiro U Jr,de Mello ES

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:To clarify optimal treatment guidelines for residual or local recurrence after endoscopic resection (ER). METHODS:Eighty-six patients underwent gastrectomy due to incomplete ER and local recurrence after ER. The pathological findings of ER and gastrectomy specimens were analyzed. RESULTS:The...

journal_title：Journal of surgical oncology

authors： Song KY,Hyung WJ,Kim HH,Han SU,Cho GS,Ryu SW,Lee HJ,Kim MC,Korean Laparoscopic Gastrointestinal Surgery Study (KLASS) Group.

更新日期：2008-07-01 00:00:00

abstract：:The data on 62 patients with germinal testicular tumors seen at King Faisal Specialist Hospital and Research Centre between January 1977 and June 1983 were analyzed to determine the epidemiologic and clinical characteristics of the disease in Saudi Arabia. Fifty-seven patients were Saudis. The geographic distribution ...

journal_title：Journal of surgical oncology

authors： el-Senoussi MA,Bissada NK,el-Akkad S,Bedikian AY,Morcos R,Bull C

更新日期：1987-05-01 00:00:00

abstract：:To search for possible untoward effects of ethanol injection into a malignant tumor, a series of experiments was carried out using the model of RBT-1 carcinoma. Ten days after the inoculation of RBT-1 carcinoma into the rat liver, the animals were separated into three groups: Group A, ethanol injection during relaparo...

journal_title：Journal of surgical oncology

authors： Ikeda Y,Matsumata T,Adachi E,Nishizaki T,Sugimachi K

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The purpose of this study was to compare the complications and functional outcome associated with the use of an irradiated allograft-implant composite or a bone-ingrowth modular tumor prosthesis for replacement of the knee joint after resection of a bone sarcoma from the distal femur or proxim...

journal_title：Journal of surgical oncology

authors： Wunder JS,Leitch K,Griffin AM,Davis AM,Bell RS

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:Gastric cancer (GC) in Israel remains incompletely characterized. The aim of this study was to define the clinical and pathological characteristics of GC in Israel and to compare them to the general Western population. PATIENTS AND METHODS:This is a retrospective analysis of 461 consecutive GC patients trea...

journal_title：Journal of surgical oncology

authors： Dreznik A,Purim O,Idelevich E,Kundel Y,Sulkes J,Sulkes A,Brenner B

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Brain metastasis is a rare but dismal event in sarcomas. However, the pattern of occurrence and the prognostic factors associated with post-brain metastasis survival (PBMS) are not yet well-characterized. METHODS:Sarcoma patients treated at one institute within 10-year period were retrospectiv...

journal_title：Journal of surgical oncology

authors： Chou YS,Liu CY,Chen WM,Chen TH,Chen PC,Wu HT,Shiau CY,Wu YC,Liu CL,Chao TC,Tzeng CH,Wong TT,Yen CC

更新日期：2011-12-01 00:00:00

abstract：:A patient with a feminizing malignant Leydig cell tumor is presented. Hormonal assays revealed increased production of prolactin, estradiol, and total estrogens. Eleven years after the onset of his disease he remains clinically well. ...

journal_title：Journal of surgical oncology

authors： Shapiro CM,Sankovitch A,Yoon WJ

更新日期：1984-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Uncertainty exists about the value of cancer therapy in patients aged 90 years and older. Because of the relative paucity of these patients, as well as the possibility of selection bias in any one institution, the use of a large, total population-based cancer registry was employed. METHODS:Th...

journal_title：Journal of surgical oncology

authors： Saltzstein SL,Behling CA

更新日期：2002-11-01 00:00:00