Abstract:
:A retrospective study was made of 38 myosarcomas of the small and large intestines (34 leiomyosarcomas and 4 malignant leiomyoblastomas). Endoenteric, small, and noninvasive tumors were successfully treated by simple wedge excision, cautery snare removal, or segmental bowel resection with a high 5-yr cure rate of 86% (12/14). Exo-enteric tumors often invaded adjacent structures or perforated into the peritoneal cavity. Extensive resection procedures, including pancreaticoduodenectomy, abdominoperineal resection, and pelvic exenteration salvaged only 13% (2/16) of these patients. Three clinicopathologic factors adversely affected prognosis: i) tumor size greater than 5 cm in diameter, ii) extra-intestinal invasion or free perforation, and iii) high histopathologic grade of malignancy. The presence of none, one, two, or three of these adverse factors gave decreasing 5-yr survival rates of 100, 44, 31, and 0%, respectively. These observations suggest use of a multimodal treatment program that may minimize treatment failure from local as well as distant disease.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Shiu MH,Farr GH,Egeli RA,Quan SH,Hajdu SIdoi
10.1002/jso.2930240116subject
Has Abstractpub_date
1983-09-01 00:00:00pages
67-72issue
1eissn
0022-4790issn
1096-9098journal_volume
24pub_type
杂志文章abstract::We retrospectively studied the relationship between nutritional status as indicated by the presence or absence of the cutaneous delayed hypersensitivity response and treatment-related morbidity, disease recurrence, and survival at 2 years in 67 consecutive patients with head and neck carcinoma. Serial nutritional asse...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930550110
更新日期:1994-01-01 00:00:00
abstract:PURPOSE:We assessed which classification of lymph node metastasis better predicted outcomes in patients with colorectal carcinoma. METHODS:We identified 318 patients (176 men) with stage III colon cancer who underwent curative resection. The number of LNs dissected, LNR, and disease-free survival time, were analyzed. ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21273
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to determine the patient reasoning behind treatment choice after palliative surgical consultation. METHODS:Patients undergoing palliative surgical consultation were prospectively enrolled in this observational cohort study (11/2009-5/2011) and administered an open-ended questio...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23215
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:The benefit of adjuvant chemotherapy for patients with locally advanced rectal cancer who have received neoadjuvant concurrent chemoradiation therapy (CCRT) and undergone curative resection remains unclear. METHODS:This study was a retrospective review of prospectively collected data. Patients with locally ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23835
更新日期:2015-03-15 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The use of antibiotic prophylaxis for soft tissue sarcoma resection varies widely while little evidence on this topic exists. The aim of this study was to determine the impact of antibiotic prophylaxis on the occurrence of wound infections. METHODS:A single institutional retrospective cohort ...
journal_title:Journal of surgical oncology
pub_type: 临床试验,杂志文章
doi:10.1002/jso.26188
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Increased activity of Src has been found in several human cancers, and often is associated with poor clinical outcome. The present study aimed to determine whether Src activity is increased in gastrointestinal stromal tumors (GIST), and whether it correlates with established tumor or patient characteristics ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23544
更新日期:2014-05-01 00:00:00
abstract::Fifty-four patients with advanced upper gastrointestinal cancer were assessed for their nutritional status prior to any form of therapy. Anthropometric parameters--weight loss, arm muscle circumference, skin-fold thickness--and biochemical parameters--serum albumin and delayed cutaneous hypersensitivity reactions to p...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930290417
更新日期:1985-08-01 00:00:00
abstract::Esophageal small cell carcinoma is a highly aggressive disease, and no effective treatment has yet been reported. We present here two cases of esophageal small cell carcinoma preoperatively treated with a combination of hyperthermia, irradiation, and an intravenous infusion of cis-diammine-dichloroplatinum (CDDP). The...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930590115
更新日期:1995-05-01 00:00:00
abstract:BACKGROUND:A tracheobronchial injury is an uncommon complication of an esophagectomy. Differences in outcomes may exist for patients with injuries detected intraoperatively and postoperatively. METHODS:A retrospective review was performed for patients who underwent an esophagectomy for cancer at Jackson Memorial Hospi...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23577
更新日期:2014-06-01 00:00:00
abstract::Colorectal cancer progression originates when accumulated genetic and epigenetic alterations cause genomic instability and a malignant phenotype. Subsequent molecular pathway deregulation leads to histopathologic changes that are clinically evident as aberrant crypt foci (ACF) and visualized by high-magnification chro...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.21106
更新日期:2008-09-01 00:00:00
abstract::Most solid tumors have now been reported to contain stem cell-like cells called cancer stem cells (CSCs). These cells are endowed with high tumorigenic capacity and may be the cells that drive tumor formation, maintain tumor homeostasis, and mediate tumor metastasis. Since these self-renewing cancer cells may be the s...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.21806
更新日期:2011-05-01 00:00:00
abstract:BACKGROUND:This retrospective study was conducted to compare the treatment and quality of life (QOL) results between radical surgery and definitive chemoradiotherapy (CRT) for stage II-III carcinoma of the esophagus. METHODS:Between 2000 and 2009, 128 consecutive patients were selected for this study in which 72 were ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21361
更新日期:2009-11-01 00:00:00
abstract::In order to determine whether current programs for the management of metastatic breast cancer have led to improved patient survival, we determined the median survival times for five-year intervals of 849 patients admitted to the City of Hope National Medical Center with metastatic breast cancer from 1955 to 1980. Surv...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930480304
更新日期:1991-11-01 00:00:00
abstract::Correlations between levels of tissue polypeptide antigen (TPA) in serum and histologic stage or progression of cancer were studied in 94 patients with gastric cancer. Levels of TPA in serum from patients with cancerous invasion into the vein of the stomach wall (v-invasion) were elevated in parallel to the progressio...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930410214
更新日期:1989-06-01 00:00:00
abstract::The clinicopathologic features of 118 granular cell tumors (GCT) encountered at two affiliated hospitals were reviewed. A total of 110 patients were affected over this 32-year period of study (71 men, 39 women), and in 5% GCT were multiple. Patients ranged in age from 16 to 58 years (average 32 years) and were symptom...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930130405
更新日期:1980-01-01 00:00:00
abstract::Between 1985 and 1991, we randomly assigned 77 women over the age of 70 years with stage I-3a breast cancer to undergo a modified radical mastectomy or tumour excision followed by tamoxifen. Median follow-up was 45 months. Patients treated by tumour excision and tamoxifen had a significantly better survival (P = 0.04)...
journal_title:Journal of surgical oncology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/jso.2930590304
更新日期:1995-07-01 00:00:00
abstract::A case of desmoid tumor of 17 years' duration associated with cystosarcoma phyllodes of 17 months' duration is presented. Good initial response to radiation therapy of the desmoid tumor was shown. Poor response of cytosarcoma phyllodes to radiation therapy was noted. A comparison between the similarities and differenc...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930080107
更新日期:1976-01-01 00:00:00
abstract::Microsurgical techniques have revolutionized pharyngolaryngeal reconstruction. Free flap reconstruction with the free jejunal flap enables one stage reconstruction with minimal morbidity and mortality. This review will examine indications, operative technique, postoperative management, and expected outcomes for the hy...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.20483
更新日期:2006-11-01 00:00:00
abstract:OBJECTIVES:To investigate predictors of occult nipple-areolar complex (NAC) involvement in patients with carcinoma in situ (CIS) and to validate an online probability calculator (CancerMath; www.lifemath.net/cancer/breastcancer/nipplecalc/index.php). METHODS:Mastectomized patients with CIS (n = 104) were retrospective...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24768
更新日期:2017-12-01 00:00:00
abstract::Three patients treated with bilateral subcutaneous mastectomies and implants for fibrocystic disease or carcinoma in situ subsequently developed invasive breast carcinoma. These cases emphasize that subcutaneous mastectomy does not prevent the development of breast cancer. If the circumstances in an individual patient...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930260313
更新日期:1984-07-01 00:00:00
abstract::Over the last decade, the use of neoadjuvant chemo-radiation has been an integral part of the care of patients with locally advanced rectal cancer. However, emerging data are beginning to challenge the current treatment paradigm of neoadjuvant chemo-radiation followed by radical resection and subsequent adjuvant chemo...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.24267
更新日期:2016-09-01 00:00:00
abstract::A retrospective analysis was performed of 20 patients with Ewing's sarcoma treated by combined modality therapy, consisting of surgery, radiotherapy, and chemotherapy. Fourteen patients (70%) achieved complete remission and 5 patients (25%) were in partial remission at the end of treatment. One patient (5%) failed to ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930480110
更新日期:1991-09-01 00:00:00
abstract:BACKGROUND:Reconstruction after excision of the humeral malignancy is a challenging issue for the reconstructive surgeon. The combined use of a fibular flap and allograft can provide a reliable reconstructive option. This article describes the authors' experience with this technique for the treatment of segmental bone ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21922
更新日期:2011-09-01 00:00:00
abstract::Fifteen malignant melanomas were subjected to chromosomal analysis, in order to determine whether the number of chromosomes in a tumor cell could be correlated to a clinical prognosis. The protocol involved a direct technique which utilized a Colcemid blockade of spindle formation in mitosis to allow study of metaphas...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930110107
更新日期:1979-01-01 00:00:00
abstract::Xenografts of a human pancreatic carcinoma cell line, HPC-YS, which reacted with the monoclonal antibody (MAb) A7, were used to investigate the in vivo localization of radioiodinated MAb A7 after intraperitoneal injection. MAb A7 localized to the tumor 4 days and 8 days after injection with a tissue/blood ratio of 1.4...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930500309
更新日期:1992-07-01 00:00:00
abstract::Retroperitoneal sarcomas (RPS) frequently involve major vessels, which either originate from them or secondarily encase or invade them. In this field, major vascular resections result in increased morbidity. However, survival does not seem to be affected by the need for vascular resection or by this higher morbidity. ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.24920
更新日期:2018-01-01 00:00:00
abstract::Between 1979 and 1993, 665 Japanese patients with advanced gastric cancer underwent surgery at our hospital. These patients were divided into two groups, consisting of 102 patients with Borrmann type IV carcinoma, and the remaining 563 patients with all other types of gastric carcinoma, which were then compared clinic...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930580208
更新日期:1995-02-01 00:00:00
abstract::The records of 30 patients with primary gastric lymphoma and a minimum of 5 years of follow-up were reviewed and clinical and pathologic prognostic factors analyzed. The overall 5-year survival was 40% (median 23 months). No significant relationship between surgical and patient age, sex, duration of symptoms, macrosco...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930540306
更新日期:1993-11-01 00:00:00
abstract::Neoadjuvant systemic breast cancer therapy is the administration of systemic therapy to eligible breast cancer patients prior to surgery. This treatment modality was developed out of necessity to downstage inoperable tumors, but it has evolved into a tool for breast conservation surgery. The neoadjuvant approach is al...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.21696
更新日期:2011-03-15 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Hyaluronic acid binding protein 1 (HABP1), a family of proteins interacting with hyaluronan (HA), had been associated with cell adhesion and tumor invasion. The aim of this study was to investigate the correlation between clinicopathologic factors and patient survival time with the expression ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21329
更新日期:2009-10-01 00:00:00