Nutritional support and prognosis in patients with head and neck cancer.

Abstract:

:We retrospectively studied the relationship between nutritional status as indicated by the presence or absence of the cutaneous delayed hypersensitivity response and treatment-related morbidity, disease recurrence, and survival at 2 years in 67 consecutive patients with head and neck carcinoma. Serial nutritional assessments were conducted throughout the course of combined initial antineoplastic treatment and nutritional support. The presence of cell-mediated immunity at the end of treatment was associated with a 2-year survival rate of 100%, whereas patients who were anergic at the end of treatment had a 2-year survival rate of 48% (P < 0.01). Morbidity due to surgical therapy and tumor recurrence rates were also higher in the anergic group (P < 0.01). Prognosis in head and neck cancer is based on many factors, but vigorous nutritional support during initial treatment may have some effect on morbidity, tumor recurrence, and survival time.

journal_name

J Surg Oncol

authors

Lopez MJ,Robinson P,Madden T,Highbarger T

doi

10.1002/jso.2930550110

subject

Has Abstract

pub_date

1994-01-01 00:00:00

pages

33-6

issue

1

eissn

0022-4790

issn

1096-9098

journal_volume

55

pub_type

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