Abstract:
BACKGROUND:Malignant hip lesions can be managed operatively by intramedullary (IM) nail fixation and hemiarthroplasty. METHODS:A retrospective review was performed on 86 patients who underwent hemiarthroplasty (n = 22) or IM nail fixation (n = 64) for prophylactic treatment of impending pathologic fracture due to malignant lesions of the hip. Cox proportional hazards and logistic regression modeling were performed to determine risk of death, fixation failure, pain relief, and return to ambulation without gait aids. RESULTS:Median survival time after surgery was 8.8 months (with no difference in survival between hemiarthroplasty and IM nail [adjusted Hazard Ratio 1.40, CI 0.72, 2.53; P = 0.31]). Hemiarthroplasty was associated with lower risk of pathologic fracture, fixation failure, or reoperation (adjusted HR 0.02, CI < 0.001, 0.48; P = 0.01). Hemiarthroplasty did not increase odds of unassisted ambulation compared to IM nail fixation (adjusted Odds Ratio [OR] 2.23, CI 0.56, 9.71; P = 0.26). The strongest predictor of postoperative ambulation was preoperative ambulation without aids (adjusted OR 28.9, CI 7.37, 161; P < 0.001). CONCLUSIONS:There is no difference in survival or likelihood of unassisted ambulation after prophylactic femoral fixation with IM nails versus hemiarthroplasty in patients with metastatic disease of proximal femur.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Lin JS,Santiago-Torres JE,Everhart JS,Zayan NE,Mayerson JL,Scharschmidt TJdoi
10.1002/jso.24792subject
Has Abstractpub_date
2017-12-01 00:00:00pages
1132-1140issue
8eissn
0022-4790issn
1096-9098journal_volume
116pub_type
杂志文章abstract:BACKGROUND AND OBJECTIVES:D2-40 staining has been reported to be useful for both identifying lymphatic vessel invasion (LVI) and counting lymphatic vessel density (LVD) in various cancers. The aim of this study was to clarify the prognostic significance of D2-40 staining in patients with esophageal squamous cell carcin...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.22079
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Argyrophilic nucleolar organizer regions (AgNORs) have been recently identified as a marker of proliferative index in various tumors. These were evaluated in 46 patients with primary breast carcinoma and were correlated with clinical prognostic parameters of breast cancer. Ten patients with be...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9098(199707)65:3<201::aid-jso10
更新日期:1997-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:We performed a retrospective analysis to assess the influence of different prognostic factors, including the International Prognostic Index (IPI), that can predict the outcome in patients with primary large bowel lymphoma (Stage IE) treated with combined therapy (surgery followed by chemothera...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.10103
更新日期:2002-06-01 00:00:00
abstract::A study was undertaken to investigate the addition of heparin and pseudomonas vaccine to BCNU in the treatment of patients with progressive malignant melanoma refractory to front-line therapeutic regimens containing DTIC. Out of 27 evaluable patients, there was one partial remission (4%), and an additional ten patient...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930160113
更新日期:1981-01-01 00:00:00
abstract::We report a case of transitional cell carcinoma of the anterior male urethra. Unlike squamous cell carcinoma of the anterior urethra, which usually requires partial penectomy, transitional cell carcinoma of this location can be managed with conservative local resection and preservation of the penis. Possible explanati...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930210212
更新日期:1982-10-01 00:00:00
abstract::In a test of electromagnetic induction hyperthermia to deep viscera of a live dog model, we found that heating was not uniform to any depth, but was quite variable. In general, there was a thermal gradient between peripheral and central portions of the transposed spleen of about 1 degree C. Though heat generation with...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930290204
更新日期:1985-06-01 00:00:00
abstract::Forty-one patients with marginally resectable stage III M0 non-small cell lung cancer (NSCLC) were entered into a study evaluating neoadjuvant cyclophosphamide, adriamycin, and cisplatin chemotherapy (CAP) followed by radiotherapy and subsequent resection. Postoperative radiotherapy and additional CAP were also admini...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930400413
更新日期:1989-04-01 00:00:00
abstract::The clinical experience is reviewed in 597 Norwegian testicular cancer patients (age range: 15-45 years) treated from 1979 to 1986. During this period, computer tomography, determination of serum AFP/HCG, and cisplatin-based chemotherapy represented the modern diagnostic and therapeutic modalities. Before orchiectomy ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.2930390110
更新日期:1988-09-01 00:00:00
abstract::The choice of palliative therapy in patients with carcinoma of the lower esophagus and cardia is mainly between irradiation and surgery. The present report is a retrospective analysis of 40 consecutive patients who recovered after resection of the tumor. The operation was considered to be palliative in all patients. T...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930320402
更新日期:1986-08-01 00:00:00
abstract::Three cases of metastatic cancer to inguinal lymph nodes from unknown primaries are presented. All three patients had exhaustive workups which produced no primary lesions. There were two cases of metastatic squamous cell carcinoma and one of melanoma. A review of the literature shows that it is unusual to have metasta...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930170107
更新日期:1981-01-01 00:00:00
abstract:BACKGROUND:In the United States, pulmonary adenocarcinomas have recently replaced squamous cell carcinomas as the most frequent type of lung cancer encountered. The incidence of pulmonary adenocarcinoma continued to increase worldwide. METHOD:To determine the roles of the transforming growth factor-beta 1 (TGF-beta 1)...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9098(199704)64:4<262::aid-jso3>
更新日期:1997-04-01 00:00:00
abstract::Robotic-assisted laparoscopy is now the most common surgical method for treatment of early-stage endometrial, cervical, and a growing number of ovarian cancers in the U.S. Para-aortic and pelvic lymphadenectomy is integral to surgical staging and subsequent treatment planning. This article reviews current staging outc...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.24005
更新日期:2015-12-01 00:00:00
abstract::Diffuse malignant peritoneal mesothelioma (DMPM) is an uncommon and locally aggressive tumor with poor prognosis. Currently, no standard therapy is available. The biology of this disease is still poorly understood. We performed a systematic search of relevant studies on clinical management and biological research of D...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.21787
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:Sentinel node biopsies (SNBs) have been clinically applied in melanoma and breast cancer for limited lymphadenectomy. However, the use of SNB remains controversial in gastric cancer due to unsatisfactory sensitivity and variability. This meta-analysis was performed to determine the sensitivity of SNB in gast...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,meta分析
doi:10.1002/jso.21995
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:Immunoreactivity for p53 tumor suppressor gene product is commonly found in human malignancies and some premalignant lesions, but its role in cancer development and its value as a marker of tumor biologic behavior is still unclear. OBJECTIVES:This study was undertaken to assess p53 immunoexpression in esoph...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9098(199705)65:1<3::aid-jso2>3.
更新日期:1997-05-01 00:00:00
abstract:INTRODUCTION:The role of adjuvant chemotherapy (AC) for synovial sarcoma (SS) is controversial. Using a large national dataset we evaluate the impact of AC on overall survival (OS) following curative-intent resection of SS. METHODS:Patients with stage I-III SS 2004-2012 undergoing resection were identified in the Nati...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24688
更新日期:2017-09-01 00:00:00
abstract:PURPOSE:The aim of this study was to determine which clinicopathological factors influenced the long-term survival after potentially curative resection of patients with colon cancer having fewer than 12 retrieved lymph nodes. METHODS:Prospective data were collected from 179 patients who had fewer than 12 resected lymp...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.22072
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:F-18 fluorodeoxyglucose-positron emission tomography (FDG-PET) has been used for diagnosis and staging of malignant diseases. However, the prognostic significance of FDG uptake on PET had not been sufficiently evaluated in patients with biliary carcinoma. METHODS:We performed a retrospective ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21356
更新日期:2009-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Whether bowel preparation utilization rates or effectiveness varies based on tumor location is unknown. METHODS:The 2012-2016 American College of Surgeons National Surgical Quality Improvement Program Colectomy Targeted participant user file was queried for patients undergoing elective colorec...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.26224
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:Surgical resection provides the only potentially curative treatment of pancreatic cancer. Neoadjuvant chemotherapy and/or radiation (NAT) is used to downstage patients with borderline resectable tumors. The objective of this study was to examine the postoperative morbidity and mortality of NAT after pancreat...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25183
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:We aim at the association of macrophage migration inhibitory factor (MIF) with neovascularization and survival of nasopharyngeal carcinoma (NPC), and determine whether MIF is a valuable prognostic predictor for NPC patients. METHODS:One hundred and forty one cases of NPC and 25 normal tissues...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21728
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Despite precipitous drop in the incidence of gastric carcinoma in Japan, it is still one of the leading causes of death associated with malignant disease. Once the contiguous organs are involved the prognosis becomes dismal. Prognostic factors governing the survival of patients with T4 gastric...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.1046
更新日期:2001-04-01 00:00:00
abstract::Prognosis of peritoneal carcinomatosis (PC) from GI tract cancers remains poor. As 30% of patients develop PC after curative surgery, prevention of PC during cancer resection would be desirable. Regarding physiopathology of PC and intraperitoneal immunology, intraoperative application of trifunctional antibodies offer...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.21338
更新日期:2009-09-15 00:00:00
abstract:BACKGROUND AND OBJECTIVES:To evaluate the predicting value of the epidermal growth factor receptor (EGFR) for survival in patients with head and neck cancer (HNC). METHODS:Data were collected from studies comparing overall survival (OS) or progression-free survival (PFS) in patients with higher or lower EGFR levels. S...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,meta分析
doi:10.1002/jso.23406
更新日期:2013-11-01 00:00:00
abstract:PURPOSE:We assessed which classification of lymph node metastasis better predicted outcomes in patients with colorectal carcinoma. METHODS:We identified 318 patients (176 men) with stage III colon cancer who underwent curative resection. The number of LNs dissected, LNR, and disease-free survival time, were analyzed. ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21273
更新日期:2009-09-01 00:00:00
abstract::Several months (an average of 12.86 months) after perineal needling of the cancerous prostate for the purpose of obtaining tissue for biopsy, a tumor nodule becomes clinically evident in the subcutaneous tissue of the perineum, at the site of the needling in 0.34% of the cases. This nodule presents the same histologic...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.2930350309
更新日期:1987-07-01 00:00:00
abstract:BACKGROUND:Adjuvant radiation is rarely used to treat medullary thyroid carcinoma (MTC). We hypothesized that external beam radiation therapy (EBRT) would improve overall survival (OS) in MTC patients. METHODS:The Surveillance, Epidemiology, and End Results (SEER) database identified patients who underwent total thyro...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21557
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND:Amongst various options of vascularized lymph node transfers, the submental flap has the lowest risk for iatrogenic lymphedema. The aim of this study was to gain insight into distribution, number, and size of lymph nodes along the mandible using computed tomography angiography (CTA). METHODS:A total of 52 C...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.26117
更新日期:2020-07-15 00:00:00
abstract::A consecutive series of 100 patients affected by gastrointestinal malignancies entered a prospective controlled study of liver metastases performed by ultrasound echography, CEA, hepatic enzymes (only alkaline phosphatase (AP) was found to be somehow significant). Laparotomic inspection and palpation were taken as obj...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930280302
更新日期:1985-03-01 00:00:00
abstract::An unusual case of Merkel cell carcinoma of the lower lip with metastasis to the submental nodes is presented. Clinical similarities and the histopathologic and prognostic differences between this tumor and basal or squamous cell carcinomas of the head and neck area are discussed and the current thoughts for treatment...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930370212
更新日期:1988-02-01 00:00:00