Abstract:
BACKGROUND AND OBJECTIVES:D2-40 staining has been reported to be useful for both identifying lymphatic vessel invasion (LVI) and counting lymphatic vessel density (LVD) in various cancers. The aim of this study was to clarify the prognostic significance of D2-40 staining in patients with esophageal squamous cell carcinoma (ESCC). METHODS:A total of 159 consecutive patients with ESCC who underwent an esophagectomy with lymph node dissection were eligible. LVI was diagnosed by both hematoxylin-eosin (LVI-HE) and D2-40 staining (LVI-D2-40) in the largest central sections of the entire tumors, while both the intratumoral and peritumoral LVD were counted by D2-40 staining. The correlation between the prognosis and clinicopathological factors was investigated. RESULTS:An univariate analysis revealed that tumor invasion beyond the muscularis propria, lymph node metastasis (LNM), LVI-HE, LVI-D2-40, high intratumoral LVD, and blood vessel invasion correlated with worse patients' prognosis (P < 0.05). A multivariate analysis revealed LNM to be the only independent prognostic factor in all cases (P = 0.0083). On the other hand, when the prognostic factors of 83 patients without LNM were investigated, LVI-D2-40 was revealed to be the only independent prognostic factor (P = 0.048). CONCLUSIONS:LVI detected by D2-40 staining was an independent prognostic factor in patients with node-negative ESCC.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Imamura Y,Watanabe M,Nagai Y,Baba Y,Hirashima K,Karashima R,Iwatsuki M,Yoshida N,Kinoshita K,Kurashige J,Iyama K,Baba Hdoi
10.1002/jso.22079subject
Has Abstractpub_date
2012-03-01 00:00:00pages
277-83issue
3eissn
0022-4790issn
1096-9098journal_volume
105pub_type
杂志文章abstract:BACKGROUND AND OBJECTIVES:Uncertainty exists about the value of cancer therapy in patients aged 90 years and older. Because of the relative paucity of these patients, as well as the possibility of selection bias in any one institution, the use of a large, total population-based cancer registry was employed. METHODS:Th...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.10160
更新日期:2002-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Ocular melanoma has a predilection for liver metastases. Systemic treatment is ineffective and the optimal regional therapy approach is poorly defined. Isolated hepatic perfusion (IHP) with melphalan has emerged as a viable treatment option, however a subset of patients are not candidates for ...
journal_title:Journal of surgical oncology
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doi:10.1002/jso.24984
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abstract:BACKGROUND AND OBJECTIVES:Immunohistochemical methods were used to study Tenascin (TN) expression in invasive duct cell carcinoma (IDCC) of the breast and its established prognostic factors. METHODS:We studied 115 patients with IDCC. The mean patient age was 62 years; all tumors were graded according to Scarf-Bloom an...
journal_title:Journal of surgical oncology
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abstract::At present, limb-sparing surgery is the most appropriate and acceptable treatment available for sarcomas of the extremities, although the right balance between conservative therapy and maximum efficacy has yet to be found. A better knowledge of prognostic factors may help in planning the appropriate strategy for each ...
journal_title:Journal of surgical oncology
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doi:10.1002/(SICI)1096-9098(199609)63:1<3::AID-JSO2>3.
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abstract:INTRODUCTION:National Comprehensive Cancer Network guidelines recommend that sentinel lymph node biopsy (SLNB) be discussed with patients with thin melanoma at higher risk for lymph node metastasis (T1b or T1a with positive deep margins, lymphovascular invasion, or high mitotic index). We examined the association betwe...
journal_title:Journal of surgical oncology
pub_type: 临床试验,杂志文章
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abstract::Australia has the world's highest incidence of skin cancer. Despite excellent prevention and early diagnosis education programs and an increasing percentage of the population with darker and more UV tolerant skins, skin cancer remains a major and expensive community medical problem. However, primary and secondary prev...
journal_title:Journal of surgical oncology
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abstract:BACKGROUND:Adrenal venous sampling (AVS) is the definitive evaluation for primary aldosteronism (PA). Pre-AVS cross-sectional imaging does not reduce the need for AVS. The goal of this study was to examine whether performing AVS prior to imaging could decrease the use of imaging in the evaluation of PA at a high volume...
journal_title:Journal of surgical oncology
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abstract:BACKGROUND AND OBJECTIVES:This analysis aims to evaluate the value of early surveillance within 6 months after resection for stage II/III colorectal cancer (CRC). METHODS:Patients with stage II/III CRC who received surgery with curative intent for CRC were included. CT scans of the chest, abdomen, and pelvis performed...
journal_title:Journal of surgical oncology
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更新日期:2013-12-01 00:00:00
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更新日期:1987-02-01 00:00:00
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journal_title:Journal of surgical oncology
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更新日期:2010-10-01 00:00:00
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journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
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更新日期:2018-08-01 00:00:00
abstract:INTRODUCTION:We sought to validate the commonly used prognostic models and staging systems for intrahepatic cholangiocarcinoma (ICC) in a large multi-center patient cohort. METHODS:The overall (OS) and disease free survival (DFS) prognostic discriminatory ability of various commonly used models were assessed in a larg...
journal_title:Journal of surgical oncology
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journal_title:Journal of surgical oncology
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journal_title:Journal of surgical oncology
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更新日期:1994-04-01 00:00:00
abstract::Whole breast reconstruction using autologous tissue is the gold standard in many regions of the world. Reasons include breast replacement with native skin and fat, ability to shape and mold the tissue into a breast, no foreign materials are necessary, and it lasts forever when successful. There are now many options fo...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
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更新日期:2016-06-01 00:00:00
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journal_title:Journal of surgical oncology
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journal_title:Journal of surgical oncology
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journal_title:Journal of surgical oncology
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journal_title:Journal of surgical oncology
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更新日期:2015-06-01 00:00:00
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更新日期:2009-03-15 00:00:00
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journal_title:Journal of surgical oncology
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更新日期:2020-12-01 00:00:00
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journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9098(199705)65:1<3::aid-jso2>3.
更新日期:1997-05-01 00:00:00
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journal_title:Journal of surgical oncology
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更新日期:1992-06-01 00:00:00
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journal_title:Journal of surgical oncology
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更新日期:1979-01-01 00:00:00
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journal_title:Journal of surgical oncology
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