Abstract:
BACKGROUND:CD109, a TGF-β co-receptor, is reported to be preferentially expressed during the early stages of tumorigenesis in several carcinoma types. Myxofibrosarcoma is one of the most common soft-tissue sarcomas found in elderly patients. This study aimed to elucidate the impact of CD109 expression in myxofibrosarcoma on prognosis and recurrence. METHODS:Immunohistochemical staining for CD109 was performed on archival specimens from 37 patients. The Fisher exact test was used to evaluate association between CD109 expression and other clinicopathological features. Survival analysis was performed using Kaplan-Meier curves, and the prognostic significance was evaluated using the log-rank test. Multivariate analysis of factors was performed using Cox regression analysis. RESULTS:CD109 overexpression was significantly associated with surgical stage and distant metastasis (P = 0.00499, and 0.011, respectively). The frequency of CD109 overexpression was approximately 10% and CD109 overexpression was significantly associated with decreased overall survival (P = 0.004). Five-year overall survival rates 77% and 0% for CD109-negative and CD109-positive patients, respectively. In multivariate analysis, CD109 overexpression was the only independent risk factor for poor outcome (P = 0.02; hazard ratio, 10.64; 95% confidence interval, 1.47-76.91). CONCLUSIONS:Immunohistochemical CD109 expression in myxofibrosarcoma was associated with poor prognosis.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Emori M,Tsukahara T,Murata K,Sugita S,Sonoda T,Kaya M,Soma T,Sasaki M,Nagoya S,Hasegawa T,Wada T,Sato N,Yamashita Tdoi
10.1002/jso.23934subject
Has Abstractpub_date
2015-06-01 00:00:00pages
975-9issue
8eissn
0022-4790issn
1096-9098journal_volume
111pub_type
杂志文章abstract::The tumor registry of a community hospital has been reviewed, and 60 patients with untreated colon and rectal cancer have been identified. Thirty-four patients were black and 26 patients were white. Sixty-five percent of black patients had specified colonic lesions primarily distributed in the right colon and proximal...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930290314
更新日期:1985-07-01 00:00:00
abstract::The use of plasma albumin (ALB), transferrin (TFN), prealbumin (TBPA), retinol-binding protein (RBP), triceps skin fold (TSF), and midarm muscle circumference (MAMC) as determinants of response to nutritional therapy (TPN) was investigated in 40 cancer patients during preoperative TPN. Thirty-one patients received 90%...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930290306
更新日期:1985-07-01 00:00:00
abstract::A malignant mesenchymoma consisting of nerve sheath sarcoma and liposarcoma occurred in the right median nerve of a 29-year-old man who did not have stigmata of von Recklinghausen neurofibromatosis. It produced pain at the affected part, referred pain to the palm, and weakness of muscles supplied by branches of this n...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930250214
更新日期:1984-02-01 00:00:00
abstract::Biopsies from 61 women with breast cancer were assessed for various histological features. These results were statistically analyzed for associations of gross tumor size, patient age, stage of disease, tumor hormone receptor status, with accepted systems of nuclear and histological grading for differentiation. Tumors ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930310109
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Interleukin (IL)-1α and hepatocyte growth factor (HGF) play an important role in pancreatic cancer proliferation, angiogenesis, and invasiveness. The aim of this study was to investigate the cooperative role of HGF and IL-1α in metastatic processes promoted by interactions between pancreatic c...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21530
更新日期:2010-10-01 00:00:00
abstract::Among catecholamine synthesizing enzymes, phenylethanolamine-N-methyltransferase (PNMT) exists only in adrenal and extra-adrenal pheochromocytoma has been believed not to produce adrenaline. However, adrenaline production is clinically active in some extra-adrenal cases. To investigate this controversy, the localizati...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930570312
更新日期:1994-11-01 00:00:00
abstract::The use of preoperative imaging has become routine for many reconstructive microsurgeons to help localize perforators for planning of microvascular free flaps. However, with advancements in imaging technology, perforator mapping represents only one potential benefit as virtual planning and medical modeling, and flap t...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.25194
更新日期:2018-10-01 00:00:00
abstract::About one third of leiomyosarcomas of the gastrointestinal tract do develop metastasis; and nearly 90% of the metastasis are intra-abdominal. It is said that leiomyosarcoma rarely involves regional nodes, although two series reported 8% of leiomyosarcomas of the stomach and 7% of the small intestines had nodal metasta...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930150403
更新日期:1980-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Brain metastasis is a rare but dismal event in sarcomas. However, the pattern of occurrence and the prognostic factors associated with post-brain metastasis survival (PBMS) are not yet well-characterized. METHODS:Sarcoma patients treated at one institute within 10-year period were retrospectiv...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.22011
更新日期:2011-12-01 00:00:00
abstract::A unique epileptic patient with intracranial neoplasm is reported in which a meningioma with lipomatous and osseous components was found associated with cerebral arteriovenous malformation at the same location in the right frontal lobe. The development of the leptomeningeal neoplasm may have been influenced by the und...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930260109
更新日期:1984-05-01 00:00:00
abstract::Prophylactic intravesical chemotherapy (IVC) reduces recurrence rates of superficial transitional cell carcinoma (TCC) of the urinary bladder. The patient cohort existed of 86 individuals (stage TaN0M0 or T1N0M0) superficial carcinoma of various grades of malignancy. Following initial transuretheral resection or diagn...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930600310
更新日期:1995-11-01 00:00:00
abstract::Dramatic improvements in morbidity and mortality rates following liver resections have been reported in the past decade. Consequently, the indications for hepatectomy are becoming more liberal. Many techniques of liver resection with or without vascular clamping have been reported with excellent clinical results. Tota...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/(sici)1096-9098(199909)72:1<50::aid-jso14>
更新日期:1999-09-01 00:00:00
abstract::We investigated the incidence of thyroid nodules in female uremic patients on maintenance hemodialysis using a high-frequency sonographic scanner. In 47 (21.0%) of the 224 female normal controls and 33 (55.0%) of the 60 female patients, thyroid nodules were detected. The difference in these incidences between controls...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930540405
更新日期:1993-12-01 00:00:00
abstract::Radiation therapy (RT) is an important modality in cancer treatment. However, the general perception is that melanoma is radio-resistant. High quality clinical trials are helping to establish the place of RT in select scenarios of advanced disease at primary, regional, and distant sites. New RT techniques need to be i...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.23509
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The therapeutic role of systematic lymph node dissection (LND) remains unclear in advanced epithelial ovarian cancer (EOC), especially during interval debulking surgery (IDS) performed after neoadjuvant chemotherapy (NAC). We analyzed the therapeutic and prognostic roles of systematic LND in ad...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24669
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:Esophageal cancer is increasingly recognized in younger patients. We compared clinicopathological characteristics, treatment, and survival of patients aged ≤50 years with patients aged >50 years diagnosed with esophageal cancer in the Netherlands. METHODS:From the nationwide Netherlands Cancer Registry we i...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23533
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND:Gastric cancer (GC) in Israel remains incompletely characterized. The aim of this study was to define the clinical and pathological characteristics of GC in Israel and to compare them to the general Western population. PATIENTS AND METHODS:This is a retrospective analysis of 461 consecutive GC patients trea...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.22078
更新日期:2012-03-01 00:00:00
abstract::A case of desmoid tumor of 17 years' duration associated with cystosarcoma phyllodes of 17 months' duration is presented. Good initial response to radiation therapy of the desmoid tumor was shown. Poor response of cytosarcoma phyllodes to radiation therapy was noted. A comparison between the similarities and differenc...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930080107
更新日期:1976-01-01 00:00:00
abstract:BACKGROUND:The majority of breast cancer patients in Mexico are treated through the public health system and >80% receive adjuvant chemotherapy. The aim of this prospective study was to characterize the impact of the Oncotype DX assay on adjuvant therapy decision making and the confidence in those decisions amongst pub...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23794
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The purpose of this study was to find out the risk factors associated with non-sentinel lymph node metastasis and determine the incidence of non-sentinel lymph node metastasis according to risk groups in sentinel lymph node (SLN)-positive endometrial cancer patients. METHODS:Patients who unde...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.26310
更新日期:2020-12-01 00:00:00
abstract::Follicular thyroid carcinoma, initially presenting as spinal cord compression due to metastatic lesions, is a less reported event. We present two cases of well-differentiated thyroid carcinoma that led to spinal cord compression. A thorough search of the literature revealed only five similar cases. We summarize the cl...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/(sici)1096-9098(199803)67:3<186::aid-jso8>
更新日期:1998-03-01 00:00:00
abstract::This paper reports on two patients, who both were under treatment for osteosarcoma of the femur. Treatment consisted of chemotherapy, resection of the tumour, and reconstruction with an endoprosthesis . Both patients sustained an epiphyseal fracture on two occasions after a minor trauma. Careful observations of the x-...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930260110
更新日期:1984-05-01 00:00:00
abstract::A patient with squamous cell carcinoma of the esophagus developed fatal aortoesophageal (AE) fistula following a preoperative course of combined chemotherapy plus radiation therapy. This is the first reported case of AE fistula following preoperative chemoradiotherapy. This complication is potentially correctable if s...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930480316
更新日期:1991-11-01 00:00:00
abstract::A patient-specific 3-dimensional printed model (3DPM) of a woman with breast cancer was created. Mastectomy was favored as BCS would necessitate significant breast size alteration due to the extent of disease. After review of the 3D printed model, the patient and surgeon agreed on breast-conserving surgery. Use of pat...
journal_title:Journal of surgical oncology
pub_type:
doi:10.1002/jso.25680
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:Positron emission tomography/computed tomography (PET/CT) scanning is commonly used for the preoperative staging of patients with at least intermediate thickness (>1 mm) melanomas. Its role in staging at initial diagnosis for clinically asymptomatic patients is not yet established. METHODS:We examined recor...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23549
更新日期:2014-06-01 00:00:00
abstract::The choice of palliative therapy in patients with carcinoma of the lower esophagus and cardia is mainly between irradiation and surgery. The present report is a retrospective analysis of 40 consecutive patients who recovered after resection of the tumor. The operation was considered to be palliative in all patients. T...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930320402
更新日期:1986-08-01 00:00:00
abstract::We report a case of adenocarcinoma arising in a focus of heterotopic pancreas, occurring in the stomach of a 52-year-old man. The patient presented with gastric outlet obstruction. Radiographic studies revealed thickening of the gastric wall, but endoscopy failed to reveal a mucosal abnormality. A 50% distal gastrecto...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.20087
更新日期:2004-07-15 00:00:00
abstract::There are a number of retroperitoneal pathologies that may be confused with adrenal tumors. It is important to suspect and recognize these conditions as their management and work up might be different than adrenal tumors. This review will go in to the differential diagnosis and unique features of these conditions. A m...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.23133
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:Local recurrence (LR) of sacral chordoma is a difficult problem and the mortality risk associated with LR remains poorly described. The purpose of this study was to evaluate the risk of mortality in patients with LR and determine if patient age is associated with mortality. METHODS:A total of 218 patients (...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25774
更新日期:2019-11-22 00:00:00
abstract::Analysis of functional status of 197 breast cancer patients three years after curative radical mastectomy indicated a cumulative probability of disability of 25%, whereas the probability of death regardless of prior disability was 40.5%. Analysis of functional status by patient characteristics indicated that nonwhites...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930110408
更新日期:1979-01-01 00:00:00