Isolated limb infusion as a model to test new agents to treat metastatic melanoma.

Abstract:

:The limb model of in-transit disease can expand our understanding of treating melanoma because of the ease of obtaining tissue biopsies for correlative studies and the availability of preclinical animal models that allow validation of novel therapeutic strategies. This review will focus on regional therapy for in-transit melanoma as a platform to investigate novel therapeutic approaches to improve regional disease control, and help us develop insights to more rationally design systemic therapy trials.

journal_name

J Surg Oncol

authors

Lidsky ME,Speicher PJ,Jiang B,Tsutsui M,Tyler DS

doi

10.1002/jso.23502

subject

Has Abstract

pub_date

2014-03-01 00:00:00

pages

357-65

issue

4

eissn

0022-4790

issn

1096-9098

journal_volume

109

pub_type

杂志文章,评审
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  • Transitional cell carcinoma of the anterior urethra.

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