Abstract:
OBJECTIVES:To investigate predictors of occult nipple-areolar complex (NAC) involvement in patients with carcinoma in situ (CIS) and to validate an online probability calculator (CancerMath; www.lifemath.net/cancer/breastcancer/nipplecalc/index.php). METHODS:Mastectomized patients with CIS (n = 104) were retrospectively selected. Clinicopathology and preoperative mammography, ultrasound, and magnetic resonance imaging (MRI) findings were analyzed. RESULTS:Histopathological NAC-positivity was confirmed in 20 (19.2%) patients. Short nipple-tumor distance and suspicious extension to the nipple by mammography were significant but ultrasound was not significant to predict NAC involvement. NAC-positive cases had MRI findings of shorter nipple-tumor distance in both the early and delayed phases. Multivariable regression model showed age >50 years and shorter tumor-nipple distance on the delay phase of MRI were statistically significant predictors of NAC involvement. Area under the receiver operating characteristics curve (AUC) was 0.618 when calculated by CancerMath; however, an AUC of 0.954 was achieved when distance and age were applied together as predictor. CONCLUSIONS:Mammographic and MRI findings were significant for predicting NAC involvement, with distance of the tumor from the nipple in delay phase MRI the most significant predictor of NAC involvement. Therefore, breast MRI could be beneficial for planning nipple-sparing mastectomy in patients with CIS.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Hwang H,Park S,Koo JS,Park HS,Kim SI,Cho YU,Park BW,Yoon JH,Kim MJ,Kim EKdoi
10.1002/jso.24768subject
Has Abstractpub_date
2017-12-01 00:00:00pages
1046-1055issue
8eissn
0022-4790issn
1096-9098journal_volume
116pub_type
杂志文章abstract::While hepatic resection of metastatic colorectal carcinoma is accepted as effective in selected patients, resection of metastases to other solid organs has not gained wide acceptance. We retrospectively reviewed the records of 49 patients who had resection of isolated pulmonary (18 patients) and hepatic (31 patients) ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930430303
更新日期:1990-03-01 00:00:00
abstract:BACKGROUND:Local recurrence (LR) after radical nephrectomy (RN) for kidney cancer is uncommon. Our objectives were to analyse characteristics and therapeutic options of LR after RN and to identify survival prognostic factors. MATERIALS AND METHODS:From a multi-institutional retrospective database, we identified 72 pat...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,多中心研究
doi:10.1002/jso.23473
更新日期:2014-02-01 00:00:00
abstract::The relationship between prior cholecystectomy and right-sided colon cancer was evaluated in a case-control study. The study population comprised 267 women with right-sided colon cancer (cases) and 268 women with left-sided colon cancer (controls). All patients were white females, aged between 40 and 69 years, and reg...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930300103
更新日期:1985-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Surgical procedures can cause tumor cells to disseminate into the circulatory system. Although this spread of metastatic cells will be limited by immune activity, immunosuppression tends to be the main effect resulting from surgery. The objective of this study is to assess hormonal and immunol...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21662
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The aim of this study was to evaluate the expression and prognostic roles of human ether à go-go related gene (hERG1) potassium channels in resected esophageal squamous cell carcinoma. METHODS:Expression of hERG1 protein and mRNA was detected by immunohistochemistry and reverse transcription ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20891
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Scoring systems were developed to stratify patients with colorectal liver metastases considered for liver resection into different risk groups. Such scores have never been evaluated in recurrent liver metastases. The aim of this study was to evaluate whether these scores are applicable to patients with recur...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24959
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:At present, the majority of outcome studies of survival of hepatocellular carcinoma (HCC) post-liver resection (post-LR) present actuarial survival data, which often results in overestimation of survival. We sought to evaluate the actual 10-year survival post-LR for HCC and identify variables that are associ...
journal_title:Journal of surgical oncology
pub_type: 临床试验,杂志文章
doi:10.1002/jso.26259
更新日期:2021-01-01 00:00:00
abstract::Two unusual presentations of perforated mucoid adenocarcinoma of the appendix are described. One patient presented with a large periappendicular abscess that extended into the gluteal region, the other with a retroperitoneal abscess and abscesses in the right flank and groin. Recognition of the source of the abscess m...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930250409
更新日期:1984-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Curative hepatic resection (CHR) was a modality that provides possibility of long-term survival for hepatocellular carcinoma (HCC). So far, prognostic factors of male patients with HCC after CHR remain unclear. Purposes of the present study were to identify these factors and to compare them wi...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20678
更新日期:2007-03-15 00:00:00
abstract::The use of preoperative imaging has become routine for many reconstructive microsurgeons to help localize perforators for planning of microvascular free flaps. However, with advancements in imaging technology, perforator mapping represents only one potential benefit as virtual planning and medical modeling, and flap t...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.25194
更新日期:2018-10-01 00:00:00
abstract:PURPOSE:To investigate the significance of palliative gastrectomy for different types of metastatic gastric cancer patients displaying peritoneal dissemination, hepatic metastasis, distant lymph node metastasis occurring locally during late-stage disease, and multi-organ metastases. METHODS:We performed a retrospectiv...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23158
更新日期:2012-12-01 00:00:00
abstract::In 1976 Stewart et al. (Annals of the New York Academy of Sciences 277:436-466) reported the effectiveness of adjuvant specific active immunotherapy of lung carcinoma in improving the postoperative survival of stage I lung carcinoma patients in a phase II study using lung carcinoma-associated antigen (TAA) and complet...
journal_title:Journal of surgical oncology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/jso.2930460104
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Some cases of mass-forming intrahepatic cholangiocarcinoma (ICC) are diagnosed as hepatocellular carcinoma (HCC) based on preoperative imaging and clinical findings. We investigated the backgrounds of such cases. METHODS:Sixty-seven patients with mass-forming ICC underwent surgery from 1980 to 2002. Twenty-...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20091
更新日期:2004-08-01 00:00:00
abstract:PURPOSE:To compare the local recurrence rate and overall survival between patients with circumferential resection margin (CRM) involvement by direct tumor spread and by a tumor within a lymph node. METHODS:A total of 776 patients diagnosed with rectal cancer underwent rectal resection. Patients with CRM involvement by...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25252
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:Sentinel node biopsies (SNBs) have been clinically applied in melanoma and breast cancer for limited lymphadenectomy. However, the use of SNB remains controversial in gastric cancer due to unsatisfactory sensitivity and variability. This meta-analysis was performed to determine the sensitivity of SNB in gast...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,meta分析
doi:10.1002/jso.21995
更新日期:2011-11-01 00:00:00
abstract:OBJECTIVE:To determine whether the presence of prostate stem cell antigen (PSCA) mRNA in peripheral blood can predict biochemical recurrence (BCR) after radical prostatectomy in patients with high-risk prostate cancer. METHODS:High-risk disease was defined based on the presence of any one of the following three risk f...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21445
更新日期:2010-02-01 00:00:00
abstract::Primary lymphoma of bone (PLB) is an uncommon clinical entity and a rare presentation of non-Hodgkin's lymphoma. At the Tata Memorial Hospital, over a period of 10 years from 1976 to 1985, 39 cases with a diagnosis of PLB were seen. Twenty-seven cases completed the prescribed treatment and were evaluable for treatment...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930440408
更新日期:1990-08-01 00:00:00
abstract::Lymphedema is a common condition frequently seen in cancer patients who have had lymph node dissection +/- radiation treatment. Traditional management is mainly non-surgical and unsatisfactory. Surgical treatment has relied on excisional techniques in the past. Physiologic operations have more recently been devised to...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.24337
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:The aim of this study was to analyze the potential utilization of external jugular vein (EJV) cutdown approach for totally implantable venous access device (TIVAD) placement. METHODS:This is a prospective, non-randomized, observational, uni-institutional study. All patients (n = 451) were first subjected to...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21341
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:Studies for patients with pelvic chondrosarcomas are limited. This study determines the outcome of patients with pelvic chondrosarcomas, and whether there is any association with tumors' grade, type, stage, margins and pelvic location. MATERIALS AND METHODS:We retrospectively studied 215 patients with pelvi...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23351
更新日期:2013-07-01 00:00:00
abstract:INTRODUCTION:Patients with Stage IV melanoma have limited therapeutic options with few long-term survivors. Our goal was to study the impact of metastasectomy on survival in these patients. METHODS:Patients with Stage IV melanoma were identified from the Surveillance, Epidemiology, and End Results (SEER) database (198...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21903
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Remifentanil infusion is used as an intraoperative anesthetic for thyroidectomy, but has been associated with acute opioid tolerance and hyperalgesia. A national shortage of remifentanil provided an opportunity to study postoperative pain in patients undergoing thyroidectomy. METHODS:Retrospe...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25746
更新日期:2019-12-01 00:00:00
abstract::Mice with intravesical urothelial tumors (MBT-2) were challenged with E coli inoculated intravesically. Adherence of bacteria measured at 15 min or persistent infection at 24 h was significantly greater in the tumor-bearing bladders than in normal non-tumor-bearing mice. The tumor-bearing portion of the bladder contai...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930230405
更新日期:1983-08-01 00:00:00
abstract:OBJECTIVES:To develop and validate a nomogram to estimate the pretest probability of malignancy in Chinese patients with solid solitary pulmonary nodule (SPN). MATERIALS AND METHODS:A primary cohort of 1798 patients with pathologically confirmed solid SPNs after surgery was retrospectively studied at five institutions...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,多中心研究
doi:10.1002/jso.24704
更新日期:2017-11-01 00:00:00
abstract::Do age, associated diseases, general state, or the stage of tumor determine the operability of breast cancer in the elderly? Risk factors are studied on the basis of data on 465 patients over 70 years of age who had breast cancer surgery between 1977 and 1986. Operative mortality of patients is analyzed, and according...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930410108
更新日期:1989-05-01 00:00:00
abstract::A case of symptomatic granular cell tumor of the esophagus is described. Another 32 cases collected from the English literature are analyzed. The reported cases have occurred mostly in women of less than 50 years of age presenting with dysphagia. Excision of the lesion is curative. ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930330409
更新日期:1986-12-01 00:00:00
abstract:BACKGROUND:Local recurrence (LR) of sacral chordoma is a difficult problem and the mortality risk associated with LR remains poorly described. The purpose of this study was to evaluate the risk of mortality in patients with LR and determine if patient age is associated with mortality. METHODS:A total of 218 patients (...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25774
更新日期:2019-11-22 00:00:00
abstract::We studied 148 colorectal adenocarcinomas to clarify any correlation between HLA-DR antigen expression on tumor cells and histopathological features. Paraffin sections of formalin-fixed tissues were stained with HLA-DR antigen using the indirect immunoperoxidase technique. All the tumor tissues were divided into two g...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930590407
更新日期:1995-08-01 00:00:00
abstract::Fresh homogenized mammary gland adenocarcinoma (C3HBA) material was subcutaneously inoculated in the anterior right thigh of transplant host mice (C3H/HeJ). When tumors were palpable, the mice were separated into three groups. The test group received biweekly intratumoral injections of Mycobacterium ulcerans filtrate ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930110210
更新日期:1979-01-01 00:00:00
abstract::The poor outcome associated with surgical resection alone for most patients with locoregional esophageal cancer has generated intensive investigation of combined-modality treatment approaches that include systemic chemotherapy. This review discusses the current role of chemotherapy in the treatment of patients with ad...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.20364
更新日期:2005-12-01 00:00:00