Abstract:
BACKGROUND AND OBJECTIVES:The use of antibiotic prophylaxis for soft tissue sarcoma resection varies widely while little evidence on this topic exists. The aim of this study was to determine the impact of antibiotic prophylaxis on the occurrence of wound infections. METHODS:A single institutional retrospective cohort study was performed on patients who underwent truncal or extremity soft tissue sarcoma resection. The use of antibiotic prophylaxis was assessed and univariate and multivariate analysis of predictors of wound infections was performed. RESULTS:Nine hundred and fifty-eight patients could be included. Thirty-two percent of patients had no antibiotic prophylaxis, 44% of patients received single-shot prophylaxis, and 24% of patients received single-shot plus continued antibiotic treatment. Wound infections occurred in 140 patients (15%). Independent risk factors for wound infections upon multivariate analysis were obesity, high American Society of Anesthesiologists (ASA) status, high tumor size and grade, operation time over 120 minutes, and other complications. Antibiotic prophylaxis could not be identified as a protective factor in univariate or multivariate analysis. CONCLUSIONS:A favorable effect of antibiotic prophylaxis on the occurrence of wound infections could not be observed. Although more studies on this subject are needed, our data do not support the general use of antibiotic prophylaxis for soft tissue sarcoma resection.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Dadras M,Koepp P,Wagner JM,Wallner C,Sogorski A,Lehnhardt M,Harati K,Behr Bdoi
10.1002/jso.26188subject
Has Abstractpub_date
2020-12-01 00:00:00pages
1685-1692issue
8eissn
0022-4790issn
1096-9098journal_volume
122pub_type
临床试验,杂志文章abstract:BACKGROUND AND OBJECTIVES:The optimal extent of lymphadenectomy in patients with esophageal cancer is controversial. This study aimed to examine the therapeutic value of lymph node (LN) dissection for each LN station in patients with esophageal squamous cell carcinoma (ESCC) who receive neoadjuvant chemotherapy. METHO...
journal_title:Journal of surgical oncology
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abstract:BACKGROUND AND OBJECTIVES:To compare 3-year clinical outcomes of radiofrequency ablation (RFA) targeting 5- or 10-mm margins for small hepatocellular carcinomas (HCCs) in cirrhotic patients. METHODS:In total, 96 cirrhotic patients with a small solitary HCC (diameter ≤3 cm) were included in this prospective trial (ChiC...
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abstract:BACKGROUND:Receptor-binding cancer antigen expressed on SiSO cells (RCAS1) has been reported to act as a ligand for a receptor present on normal peripheral lymphocytes and to induce apoptotic cell death. We aimed to elucidate the significance of RCAS1 expression in human esophageal squamous cell carcinomas (ESCC). MET...
journal_title:Journal of surgical oncology
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abstract::A 38-year-old woman with early stage invasive breast cancer was treated with wide excision of the tumor, axillary lymph node dissection, and breast irradiation. Three years later, she gave birth to a normal baby. She attempted breast feeding and had full lactation from the untreated breast. The irradiated breast under...
journal_title:Journal of surgical oncology
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doi:10.1002/jso.2930460214
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journal_title:Journal of surgical oncology
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doi:10.1002/jso.23835
更新日期:2015-03-15 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Malignant mesothelioma is a lethal disease. Aggressive multimodality treatment protocols are reportedly associated with improved survival, but the apparent survival benefits may simply reflect patient selection and the variable natural history of this malignancy. Before embarking on our own pr...
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journal_title:Journal of surgical oncology
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journal_title:Journal of surgical oncology
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abstract:OBJECTIVE:Gastrointestinal stromal tumors (GISTs) occur rarely in the duodenum. The characteristics of duodenal GIST have not been well clarified. The aim of this study is to clarify the characteristics and surgical prognosis of patients with primary duodenal GIST. METHODS:Data of patients with surgically treated prim...
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journal_title:Journal of surgical oncology
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journal_title:Journal of surgical oncology
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更新日期:2013-07-01 00:00:00
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journal_title:Journal of surgical oncology
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更新日期:2015-05-01 00:00:00
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journal_title:Journal of surgical oncology
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更新日期:2011-09-01 00:00:00
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journal_title:Journal of surgical oncology
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更新日期:2019-03-01 00:00:00
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journal_title:Journal of surgical oncology
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更新日期:2007-06-15 00:00:00
abstract::The relationship between prior cholecystectomy and right-sided colon cancer was evaluated in a case-control study. The study population comprised 267 women with right-sided colon cancer (cases) and 268 women with left-sided colon cancer (controls). All patients were white females, aged between 40 and 69 years, and reg...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930300103
更新日期:1985-09-01 00:00:00
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journal_title:Journal of surgical oncology
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journal_title:Journal of surgical oncology
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journal_title:Journal of surgical oncology
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journal_title:Journal of surgical oncology
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更新日期:2011-07-01 00:00:00
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journal_title:Journal of surgical oncology
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abstract::Prognostic significance of blood vessel invasion in carcinoma of the female breast has been evaluated by study of 242 cases of radical mastectomy done at the Tata Memorial Hospital. The significance of axillary node involvement with the disease has been simultaneously evaluated. In the absence of blood vessel invasion...
journal_title:Journal of surgical oncology
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abstract::We report a case of pancreatic sarcoidosis in a patient with radiographic and clinical findings suggestive of pancreatic cancer. Clinically apparent involvement of the pancreas is uncommon in patients with known sarcoidosis and is distinctly unusual as the initial presentation of disease. Sarcoid involvement of the pa...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
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更新日期:1993-10-01 00:00:00
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更新日期:2009-10-01 00:00:00