The surgeon and chemotherapy: twenty five years personal experience.

abstract：:The relationship between prior cholecystectomy and right-sided colon cancer was evaluated in a case-control study. The study population comprised 267 women with right-sided colon cancer (cases) and 268 women with left-sided colon cancer (controls). All patients were white females, aged between 40 and 69 years, and reg...

journal_title：Journal of surgical oncology

authors： Spitz MR,Russell NC,Guinee VF,Newell GR

更新日期：1985-09-01 00:00:00

abstract：BACKGROUND:Alterations in mitochondrial DNA have been identified in a number of solid tumor types, including gastric, head and neck, breast, colorectal, lung, and bladder carcinomas. Recently, a homopolymeric C stretch (D310) located within the noncoding D-loop of the mitochondrial genome was identified and described a...

journal_title：Journal of surgical oncology

authors： Tong BC,Ha PK,Dhir K,Xing M,Westra WH,Sidransky D,Califano JA

更新日期：2003-03-01 00:00:00

abstract：:Lymphoproliferative activity was assessed by 3H-thymidine incorporation in spleen cells of mammary tumor bearing BALB/c mice, mice which had their tumors surgically removed, and mice with sham surgery after stimulation in vitro with a soluble extract of syngeneic tumor antigens. Surgical removal of tumors caused an av...

journal_title：Journal of surgical oncology

authors： Laing CA,Japal KM,Baker ME

更新日期：1987-05-01 00:00:00

abstract：:The history of a patient presenting with metachronous bilateral breast cancer displaying histiocytoid features is reviewed. Although regional metastases were noted, this patient has not demonstrated an aggressive systemic disease pattern. In the past, histiocytoid breast cancer has been classified as either a lipid-ri...

journal_title：Journal of surgical oncology

authors： Eisenberg BL,Bagnall JW,Harding CT 3rd

更新日期：1986-04-01 00:00:00

abstract：:Sixteen consecutive patients entered in a prospective study of non-neurogenic soft tissue tumours had lesions in the axilla. Delayed diagnosis and inappropriate biopsy prior to referral to a surgical oncologist were frequent findings. Sarcoma and fibromatosis were diagnosed in 14 cases, and the approaches used for the...

journal_title：Journal of surgical oncology

authors： Bell RS,Ready J,Hudson A,O'Sullivan B,Mahoney J,Richards R,Davis A,Fornasier VL

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate if immunohistochemical expression and mutational status of KIT and PDGFRA in GISTs are associated with the clinical course and disease-free survival after curative resection of the primary tumor without adjuvant systemic therapy. METHODS:Paraffin-embedded tumor secti...

journal_title：Journal of surgical oncology

authors： Kern A,Görgens H,Dittert DD,Krüger S,Richter KK,Schackert HK,Saeger HD,Baretton G,Pistorius S

更新日期：2011-07-01 00:00:00

abstract：:Serum copper levels (SCL) have been done in 106 patients of squamous cell carcinoma of the cervix and in 15 cases of local recurrences. The mean SCL has been significantly elevated in them in comparison to controls (P less than 0.001). The SCL falls to near normal range following successful therapy. There is a trend t...

journal_title：Journal of surgical oncology

authors： Birdi A,Gupta S,Gambhir SS

更新日期：1983-03-01 00:00:00

abstract：OBJECTIVE:Significant controversy exists concerning the factors affecting survival after secondary cytoreduction (SCR) in recurrent ovarian cancer. This study aims to identify factors independently associated with survival after SCR. METHODS:We retrospectively retrieved 39 patients with recurrent ovarian cancer. All p...

journal_title：Journal of surgical oncology

authors： Biliatis I,Haidopoulos D,Rodolakis A,Vlachos G,Protopapas A,Thomakos N,Sergentanis T,Akrivos N,Antsaklis A

更新日期：2010-11-01 00:00:00

abstract：:A new combined cancer chemotherapy regimen of mitomycin C (MMC) and cisplatin (DDP) showed synergistic antitumor activity against human gastric cancer xenografts St-40 and SC-1-NU in BALB/c nu/nu mice. The drugs were administered intraperitoneally at doses of 2 or 4 mg/kg for MMC and 3 or 6 mg/kg for DDP, respectively...

journal_title：Journal of surgical oncology

authors： Saikawa Y,Kubota T,Kuo TH,Furukawa T,Kase S,Tanino H,Isobe Y,Watanabe M,Ishibiki K,Arimori M

更新日期：1994-08-01 00:00:00

abstract：:Radioimmunoassay for serum carcinoembryonic antigen (CEA) was performed in 49 colonic cancer patients. The test results were positive in 42 patients (85.7%) in whom tumor was present at the time of assay. Preoperatively, CEA level suggested the extent and the prognosis of the disease. Strongly positive CEA test result...

journal_title：Journal of surgical oncology

authors： Alsabti E

更新日期：1979-01-01 00:00:00

abstract：:Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasm arising in the stomach. These tumors were previously classified as smooth muscle tumors, but in recent years it has become clear that they are clinically, pathologically, and molecularly distinct from other tumors and are much more common...

journal_title：Journal of surgical oncology

authors： Heinrich MC,Corless CL

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Malignant cartilage tumors demonstrate chemotherapeutic resistance through undetermined mechanisms. P-glycoprotein is the protein product of the multiple drug resistance gene 1 (MDR-1) and confers multidrug chemotherapeutic resistance in a variety of malignancies. METHODS:MDR-1 expression was...

journal_title：Journal of surgical oncology

authors： Rosier RN,O'Keefe RJ,Teot LA,Fox EJ,Nester TA,Puzas JE,Reynolds PR,Hicks DG

更新日期：1997-06-01 00:00:00

abstract：:Diffuse malignant peritoneal mesothelioma (DMPM) is an uncommon and locally aggressive tumor with poor prognosis. Currently, no standard therapy is available. The biology of this disease is still poorly understood. We performed a systematic search of relevant studies on clinical management and biological research of D...

journal_title：Journal of surgical oncology

authors： Baratti D,Kusamura S,Deraco M

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Stages II and III rectal tumors are known as locally advanced rectal cancer (LARC) because they are characterized by a high incidence of local and distant relapses and a low probability of long-term survival. Adjuvant treatments have been advocated to ameliorate overall survival (OS), local re...

journal_title：Journal of surgical oncology

authors： Bufalari A,Boselli C,Giustozzi G,Moggi L

更新日期：2000-05-01 00:00:00

abstract：:A retrospective review to elucidate the rationale of preoperative irradiation was made on 18 carcinomas of the head of the pancreas area. After 50 Gy/25 fractions of 10 MV X-ray was given, all 18 tumors decreased from 3.3 +/- 0.8 cm to 2.0 +/- 0.7 cm. At the surgical operation, 16 patients (89%) received pancreatic re...

journal_title：Journal of surgical oncology

authors： Ishikawa O,Ohhigashi H,Teshima T,Chatani M,Inoue T,Tanaka S,Kitamura T,Wada A,Sasaki Y,Imaoka S

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Stage III malignant melanoma is a heterogeneous disease where those cases deemed marginally resectable or irresecatble are frequently incurable by surgery alone. Targeted therapy takes advantage of the high incidence of BRAF mutations in melanomas, most notably the V600E mutation. These agents...

journal_title：Journal of surgical oncology

authors： Zippel D,Markel G,Shapira-Frommer R,Ben-Betzalel G,Goitein D,Ben-Ami E,Nissan A,Schachter J,Schneebaum S

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:We evaluated the clinicopathological associations and prognostic implications of promyelocytic leukemia gene (PML) expressions in patients with esophageal squamous cell carcinomas (ESCC) receiving primary surgery. METHODS:Expression patterns of PML and tumor protein 53 (TP53) of 132 cases of ...

journal_title：Journal of surgical oncology

authors： Yen CC,Tsao YP,Chen PC,Wu YC,Liu JH,Pan CC,Liu CY,Tzeng CH,Chen PM,Chen YJ,Lin CH,Hsu WH

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Surgical resection provides the only potentially curative treatment of pancreatic cancer. Neoadjuvant chemotherapy and/or radiation (NAT) is used to downstage patients with borderline resectable tumors. The objective of this study was to examine the postoperative morbidity and mortality of NAT after pancreat...

journal_title：Journal of surgical oncology

authors： Cools KS,Sanoff HK,Kim HJ,Yeh JJ,Stitzenberg KB

更新日期：2018-09-01 00:00:00

abstract：:Fluorescence-guided surgery can enhance the surgeon's ability to achieve a complete oncologic resection. There are a number of tumor-specific probes being developed with many preclinical mouse models to evaluate their efficacy. The current review discusses the different preclinical mouse models in the setting of probe...

journal_title：Journal of surgical oncology

authors： Lwin TM,Hoffman RM,Bouvet M

更新日期：2018-08-01 00:00:00

abstract：:Surgical procedures for breast cancer were compared in 468 cases with in-situ and 4,967 cases with invasive lesions. The cases were obtained from the Michigan Cancer Foundation Registry, a Surveillance, Epidemiology, and End Results (SEER) participant, and were incident-resident cases diagnosed from 1973-1978. For sin...

journal_title：Journal of surgical oncology

authors： Albert S,Belle S,Eckert D,Swanson GM

更新日期：1982-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:We aim at the association of macrophage migration inhibitory factor (MIF) with neovascularization and survival of nasopharyngeal carcinoma (NPC), and determine whether MIF is a valuable prognostic predictor for NPC patients. METHODS:One hundred and forty one cases of NPC and 25 normal tissues...

journal_title：Journal of surgical oncology

authors： Liao B,Zhong BL,Li Z,Tian XY,Li Y,Li B

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Few studies describe quality of life (QoL) outcomes following gastrectomy for gastric cancer using a validated instrument. The gastric cancer module for the Functional Assessment of Cancer Therapy system of QoL measurement tools (FACT-Ga) was utilized to determine the changes in QoL following gastrectomy, an...

journal_title：Journal of surgical oncology

authors： Munene G,Francis W,Garland SN,Pelletier G,Mack LA,Bathe OF

更新日期：2012-03-15 00:00:00

abstract：:Between 1989 and 1991, 150 patients with ovarian cancer were treated with chemotherapy, including cisplatin, in the Tokai Ovarian Tumor Study Group. Of these patients, 25 underwent cytoreductive surgery with lymphadenectomy, including removal of either pelvic or para-aortic lymph nodes, and 36 underwent both lymphaden...

journal_title：Journal of surgical oncology

authors： Kikkawa F,Ishikawa H,Tamakoshi K,Suganuma N,Mizuno K,Kawai M,Arii Y,Tamakoshi A,Kuzuya K,Tomoda Y

更新日期：1995-12-01 00:00:00

abstract：:Prognosis of peritoneal carcinomatosis (PC) from GI tract cancers remains poor. As 30% of patients develop PC after curative surgery, prevention of PC during cancer resection would be desirable. Regarding physiopathology of PC and intraperitoneal immunology, intraoperative application of trifunctional antibodies offer...

journal_title：Journal of surgical oncology

authors： Ströhlein MA,Heiss MM

更新日期：2009-09-15 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Immunohistochemical methods were used to study Tenascin (TN) expression in invasive duct cell carcinoma (IDCC) of the breast and its established prognostic factors. METHODS:We studied 115 patients with IDCC. The mean patient age was 62 years; all tumors were graded according to Scarf-Bloom an...

journal_title：Journal of surgical oncology

authors： Iskaros BF,Hu X,Sparano JA,Fineberg SA

更新日期：1998-06-01 00:00:00

abstract：:A primary retroperitoneal dermoid cyst (benign cystic teratoma) is described in a 64-year-old male, who died postoperatively of a leaking grafted abdominal aortic aneurysm. The asymptomatic tumor, measuring 12 cm in greatest diameter, showed an extensive sclerosing lipogranulomatous reaction in its wall and wide-sprea...

journal_title：Journal of surgical oncology

authors： Honoré LH

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The aggressiveness and greater malignant potential of cancers are characterized by several biological phenomena such as accelerated growth invasiveness, and the ability to form distant metastasis. Thus, knowledge of such biological difference may be a more accurate prognosticator for cancer pa...

journal_title：Journal of surgical oncology

authors： Morinaga S,Ishiwa N,Noguchi Y,Yamamoto Y,Rino Y,Imada T,Takanashi Y,Akaike M,Sugimasa Y,Takemiya S

更新日期：2005-12-15 00:00:00

abstract：INTRODUCTION:Hyperthermic isolated limb perfusion (HILP) has an established role in the management of melanoma, but its role for Merkel cell carcinoma (MCC) is less well defined. METHODS:Retrospective review of our institutional experience with HILP for MCC was conducted (2009-2015). Literature search was performed th...

journal_title：Journal of surgical oncology

authors： Thiels CA,Gonzalez AB,Gray RJ,Jakub JW

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Angiosarcoma is an aggressive vascular neoplasm with a high propensity for local recurrence. Electrochemotherapy is an emerging skin-directed therapy, exerting prominent cytotoxic activity, and antivascular effects. Its efficacy in angiosarcoma has not been investigated. METHODS:This multicenter retrospecti...

journal_title：Journal of surgical oncology

authors： Guida M,Campana LG,Curatolo P,Strippoli S,Bonadies A,Grilz G,Cabula C,Rotunno R,Bucher S,Solari N,Santoriello A,Valpione S,Rossi CR

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Studies for patients with pelvic chondrosarcomas are limited. This study determines the outcome of patients with pelvic chondrosarcomas, and whether there is any association with tumors' grade, type, stage, margins and pelvic location. MATERIALS AND METHODS:We retrospectively studied 215 patients with pelvi...

journal_title：Journal of surgical oncology

authors： Mavrogenis AF,Angelini A,Drago G,Merlino B,Ruggieri P

更新日期：2013-07-01 00:00:00