Abstract:
BACKGROUND:Studies for patients with pelvic chondrosarcomas are limited. This study determines the outcome of patients with pelvic chondrosarcomas, and whether there is any association with tumors' grade, type, stage, margins and pelvic location. MATERIALS AND METHODS:We retrospectively studied 215 patients with pelvic chondrosarcomas. All patients had biopsy and histological diagnosis of their tumors followed by limb salvage or amputation. We staged patients using the Musculoskeletal Tumor Society system. We performed a univariate and multivariate analysis of the survival to death, local recurrence and metastasis with respect to grade, type (central vs. peripheral), stage, margins, and pelvic location, and the survival to death of patients with and without local recurrence. RESULTS:Grade was the most important univariate and multivariate predictor of the survival of the patients. Dedifferentiation was associated with significantly lower overall survival. Peripheral chondrosarcomas predicted survival only in the univariate analysis. Surgical margins predicted local recurrence only in the multivariate analysis. Periacetabular location was associated with lower survival to death and local recurrence. The occurrence of local recurrence compromises the overall survival. CONCLUSION:Grade was the most important predictor of the overall survival of patients with chondrosarcomas of the pelvis.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Mavrogenis AF,Angelini A,Drago G,Merlino B,Ruggieri Pdoi
10.1002/jso.23351subject
Has Abstractpub_date
2013-07-01 00:00:00pages
19-27issue
1eissn
0022-4790issn
1096-9098journal_volume
108pub_type
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journal_title:Journal of surgical oncology
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abstract::A rare case of metastatic malignant melanoma of unknown primary origin in a 49-year-old woman is reported. The swelling, localized in the right inguinal region, was partially immovable and associated with progressively increasing pain. Initial diagnosis was set by needle aspiration cytology and was confirmed postopera...
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更新日期:1984-03-01 00:00:00
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journal_title:Journal of surgical oncology
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更新日期:2001-01-01 00:00:00
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更新日期:2008-01-01 00:00:00
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更新日期:2019-11-29 00:00:00
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更新日期:2011-12-01 00:00:00
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journal_title:Journal of surgical oncology
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