Carcinoembryonic antigen (CEA) as prognostic marker in colonic cancer.

Abstract:

:Radioimmunoassay for serum carcinoembryonic antigen (CEA) was performed in 49 colonic cancer patients. The test results were positive in 42 patients (85.7%) in whom tumor was present at the time of assay. Preoperatively, CEA level suggested the extent and the prognosis of the disease. Strongly positive CEA test results in such patients correlated with metastatic tumors and poor prognosis. Postoperatively, a positive result for serum CEA indicated presence of residual tumor, while negative results did not exclude residual tumor. Periodic CEA determination in the patients who have undergone resection of colonic cancer may detect tumor recurrence that is at a treatable stage. The data show that patients in whom the immediate postoperative CEA concentration returns to normal have a much lower incidence of recurrent cancer of the colon than patients whose CEA level remains elevated.

journal_name

J Surg Oncol

authors

Alsabti E

doi

10.1002/jso.2930120206

subject

Has Abstract

pub_date

1979-01-01 00:00:00

pages

127-9

issue

2

eissn

0022-4790

issn

1096-9098

journal_volume

12

pub_type

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