Abstract:
:Radioimmunoassay for serum carcinoembryonic antigen (CEA) was performed in 49 colonic cancer patients. The test results were positive in 42 patients (85.7%) in whom tumor was present at the time of assay. Preoperatively, CEA level suggested the extent and the prognosis of the disease. Strongly positive CEA test results in such patients correlated with metastatic tumors and poor prognosis. Postoperatively, a positive result for serum CEA indicated presence of residual tumor, while negative results did not exclude residual tumor. Periodic CEA determination in the patients who have undergone resection of colonic cancer may detect tumor recurrence that is at a treatable stage. The data show that patients in whom the immediate postoperative CEA concentration returns to normal have a much lower incidence of recurrent cancer of the colon than patients whose CEA level remains elevated.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Alsabti Edoi
10.1002/jso.2930120206subject
Has Abstractpub_date
1979-01-01 00:00:00pages
127-9issue
2eissn
0022-4790issn
1096-9098journal_volume
12pub_type
杂志文章abstract:BACKGROUND AND OBJECTIVES:We assessed the optimal extent of lymph node dissection and the effect of splenectomy in patients with proximal gastric cancer. METHOD:Recurrence and survival rates were compared between 881 patients with proximal gastric cancer who underwent modified radical lymphadenectomy and 3,098 patient...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21137
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND:This study evaluates several tumor-related markers to examine the expression pattern of markers according to the invasiveness and histopathologic differentiation of squamous cell carcinoma and basal cell carcinoma. METHODS:Ninety-four cases of squamous cell carcinoma and 108 cases of basal cell carcinoma us...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21006
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:The primary endpoint of this study is to analyze short term benefit of laparoscopic approach (minimally invasive liver surgery [MILS]) over the open techniques in patients submitted to surgery for breast cancer liver metastases (BCLM) within a disease-specific perspective. MATERIAL AND METHODS:A group of 30...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25702
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Outcomes and recommendations regarding adjuvant therapy (AT) for stage I ampullary adenocarcinoma (AAC) are inadequately described. We sought to determine factors associated with survival and better define the impact of AT. METHODS:The NCDB was queried for stage I AAC patients undergoing rese...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25021
更新日期:2018-06-01 00:00:00
abstract:OBJECTIVES:The objective of this study is to present two series of cases of pigmented villonodular disease of joints (PVNS) treated at different periods. The 215 cases from our hospital are current (1972-2009) and those 62 from the Jaffe collection from 1920 to 1968. METHODS:By use of our computerized tumor data syste...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21835
更新日期:2011-04-01 00:00:00
abstract::Maximum diameter, tumour volume, and inflammatory response of host tissue in 282 surgical specimens with primary carcinoma of the bronchus were measured. Cell type, pT- and pN-stage, maximum diameter and volume of the primaries, and inflammatory response of host tissue were analyzed in respect to survival of the patie...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930360203
更新日期:1987-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Retinoids are metabolized in human intestinal epithelial cells to all-trans retinoic acid; however, it is unknown whether these cells express retinoid receptors, and whether sensitivity or resistance to the hormone is associated with a particular pattern of expression of retinoid-responsive ge...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9098(199711)66:3<156::aid-jso2>
更新日期:1997-11-01 00:00:00
abstract::A case of extramammary Paget's disease is reported. The distinguishing features of the case are: (1) localization of the primary lesion to the scrotum, (2) development of metastases in the absence of a recognizable underlying carcinoma, and (3) response of the systemic disease to a combination of radiation therapy and...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930380111
更新日期:1988-05-01 00:00:00
abstract::This study was done to determine why the plasma insulin remained elevated during shock. Mongrel Female dogs (12-15 kg) were depancreatized and maintained on a constant intraportal infusion of porcine insulin while they were bled to reduce and maintain the mean arterial blood pressure at 50 mm Hg for 165 min. Blood sam...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930080108
更新日期:1976-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:To identify breast-specific factors and the role of tumor, treatment, and patient-related items in influencing patient opinion on cosmesis and satisfaction after breast-conserving therapy (BCT). METHODS:Data from the randomized COBALT study was used. At 3, 12, and 36 months, 128 patients with...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,随机对照试验
doi:10.1002/jso.25012
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:In the United States, pulmonary adenocarcinomas have recently replaced squamous cell carcinomas as the most frequent type of lung cancer encountered. The incidence of pulmonary adenocarcinoma continued to increase worldwide. METHOD:To determine the roles of the transforming growth factor-beta 1 (TGF-beta 1)...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9098(199704)64:4<262::aid-jso3>
更新日期:1997-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Neoadjuvant chemotherapy (nCMT) has been increasingly used in advanced gastric cancer (GC). However, the prognostic impact of tumor response remains unclear. This study aimed to evaluate if tumor response at the primary site and lymph nodes (LN) correlate with survival in GC patients after nCMT...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25785
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The genetic alterations involved in extrahepatic bile duct (EHBD) cancer are poorly understood. Our aim was to identify aberrations of the K-ras, p53, and APC genes in EHBD cancer. METHODS:We investigated aberrations of these genes in 52 EHBD cancers using polymerase chain reaction (PCR) sing...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9098(200003)73:3<158::aid-jso9>
更新日期:2000-03-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Destructive metastatic lesions about the acetabulum result in pain and functional limitations. We assessed whether periacetabular reconstruction (PAR) improves quality of life by examining outcome measures of pain, function, and mobility. METHODS:Thirty-seven patients with a mean follow-up of 23....
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21440
更新日期:2010-02-01 00:00:00
abstract:BACKGROUND:The objective of the current study was to define the impact of albumin-bilirubin (ALBI) grade on short- as well as long-term outcomes among patients with intrahepatic cholangiocarcinoma (ICC). METHODS:Patients who underwent hepatectomy for ICC between 1990 and 2016 were identified using an international mul...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,多中心研究
doi:10.1002/jso.25486
更新日期:2019-08-01 00:00:00
abstract::Serum copper levels (SCL) have been done in 106 patients of squamous cell carcinoma of the cervix and in 15 cases of local recurrences. The mean SCL has been significantly elevated in them in comparison to controls (P less than 0.001). The SCL falls to near normal range following successful therapy. There is a trend t...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930220313
更新日期:1983-03-01 00:00:00
abstract::Dramatic improvements in morbidity and mortality rates following liver resections have been reported in the past decade. Consequently, the indications for hepatectomy are becoming more liberal. Many techniques of liver resection with or without vascular clamping have been reported with excellent clinical results. Tota...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/(sici)1096-9098(199909)72:1<50::aid-jso14>
更新日期:1999-09-01 00:00:00
abstract::A retrospective analysis was performed of 20 patients with Ewing's sarcoma treated by combined modality therapy, consisting of surgery, radiotherapy, and chemotherapy. Fourteen patients (70%) achieved complete remission and 5 patients (25%) were in partial remission at the end of treatment. One patient (5%) failed to ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930480110
更新日期:1991-09-01 00:00:00
abstract:BACKGROUND/OBJECTIVE:Staging and type of resection for rectal neuroendocrine tumors (R-NETS) relies on preoperative identification of lymph node (LN) involvement. Study objective was to develop a Preoperative Rectal Stratification Score (PReSS) for LN-positivity and to assess the association of PReSS with overall survi...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25679
更新日期:2019-11-01 00:00:00
abstract::Retroperitoneal sarcomas (RPS) frequently involve major vessels, which either originate from them or secondarily encase or invade them. In this field, major vascular resections result in increased morbidity. However, survival does not seem to be affected by the need for vascular resection or by this higher morbidity. ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.24920
更新日期:2018-01-01 00:00:00
abstract::Prognostic significance of blood vessel invasion in carcinoma of the female breast has been evaluated by study of 242 cases of radical mastectomy done at the Tata Memorial Hospital. The significance of axillary node involvement with the disease has been simultaneously evaluated. In the absence of blood vessel invasion...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930090613
更新日期:1977-01-01 00:00:00
abstract:BACKGROUND/AIMS:We compared overall survival (OS) of patients with a solitary large (>5 cm) hepatocellular carcinoma (HCC) treated surgically or by transarterial chemoembolization (TACE). METHODS:The archived records of HCC patients registered at the Korean Central Cancer Registry from 2003 through 2005 (registry A, n...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24519
更新日期:2017-03-01 00:00:00
abstract::In vivo skin tests using multiple recall and primary antigens such as dinitrochlorobenzine (DNCB) have established that there is decreased cellular-mediated immune response in patients with squamous cell carcinomas of the head and neck. In vitro testing of lymphocytes using blastogenic mitogens as a measure of lymphoc...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930090111
更新日期:1977-01-01 00:00:00
abstract::Lymph node status is not part of the staging system for cervical cancer, but provides important information for prognosis and treatment. This article reviews the incidence and patterns of lymph node metastasis, and the issues surrounding surgical assessment of lymph nodes. The preoperative assessment of lymph nodes by...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.21199
更新日期:2009-03-15 00:00:00
abstract:BACKGROUND AND OBJECTIVES:To evaluate the efficacy of preoperative ultrasound (US) scanning in identifying lymph node metastasis before sentinel node biopsy (SNB), we conducted a prospective study on 125 patients with primary cutaneous melanoma (CM). METHODS:We prospectively enrolled 125 patients with >1 mm thick CM a...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.10248
更新日期:2003-06-01 00:00:00
abstract::The T N M staging system created by a surgeon in the 1950s continues to be a major benchmark for assessing long-term outcomes in adult solid tumors. Although several major changes have occurred in this anatomical staging system, the tenets of TNM staging remain constant. Recently molecular markers and biologic modifie...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.23704
更新日期:2014-10-01 00:00:00
abstract::A large number of adrenal tumors are now identified either incidentally or associated with a metastatic workup for cancer. While the vast majority of these lesions are benign, those that prove to be primary or secondary cancers are traditionally treated with surgical resection. A wide variety of alternative, less inva...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.23191
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:In patients undergoing total mesorectal excision (TME), the clinical variables most relevant to anastomotic recurrence have not been identified. We evaluated factors associated with anastomotic recurrence in patients undergoing TME and the impact of a reduced distal margin on anastomotic recurrence. METHODS...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21166
更新日期:2009-01-01 00:00:00
abstract::Cancer registries are sources of epidemiological, patterns-of-care, and outcome data for local, regional, state, and national studies of patients with cancer. Since 1976, these registries have formed a voluntary network of contributors to annual patient care studies under the aegis of the National Cancer Data Committe...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930580304
更新日期:1995-03-01 00:00:00
abstract:INTRODUCTION:The Siewert classification has been used to plan treatment for tumours of the gastro-oesophageal junction since its proposal in the 1980s. The purpose of this study was to assess its continued relevance by evaluating whether there were differences in the biology and clinical characteristics of adenocarcino...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23484
更新日期:2014-03-01 00:00:00