Appraisal of disease-specific benefits of minimally invasiveness in surgery of breast cancer liver metastases.

Abstract:

BACKGROUND:The primary endpoint of this study is to analyze short term benefit of laparoscopic approach (minimally invasive liver surgery [MILS]) over the open techniques in patients submitted to surgery for breast cancer liver metastases (BCLM) within a disease-specific perspective. MATERIAL AND METHODS:A group of 30 patients who underwent laparoscopic liver resection for BCLM constituted the Study group (MILS group) and was matched in a ratio of 1:2 with patients who underwent open surgery for BCLM (Open group, constituting the Control group). RESULTS:MILS approach resulted in a statistically significant lower blood loss (150 vs 300 mL; P < .05). The rate of postoperative complications was similar (13.3% and 16.6% in the MILS and Open groups, respectively). MILS approach was associated with a shorter length of postoperative stay (4 ± 2 days) compared with the Open group (7 ± 3 days), allowing a faster return to adjuvant treatments. Both MILS and open groups showed adequate oncological radicality, with comparable long-term results. CONCLUSION:MILS approach to BCLM represents the optimal instrument to obtain an adequate disease clearance in the selected group of patients candidates to surgery: the type of procedure (minor resections for limited hepatic disease) and characteristics of patients contribute to enhance the feasibility and the benefits of the laparoscopic technique.

journal_name

J Surg Oncol

authors

Ratti F,Serenari M,Zanello M,Prosperi E,Cipriani F,Ercolani G,Jovine E,Cescon M,Aldrighetti L

doi

10.1002/jso.25702

subject

Has Abstract

pub_date

2019-12-01 00:00:00

pages

1169-1176

issue

7

eissn

0022-4790

issn

1096-9098

journal_volume

120

pub_type

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