Results of multimodal therapy in Ewing's sarcoma: a retrospective analysis of 20 patients.

Abstract:

:A retrospective analysis was performed of 20 patients with Ewing's sarcoma treated by combined modality therapy, consisting of surgery, radiotherapy, and chemotherapy. Fourteen patients (70%) achieved complete remission and 5 patients (25%) were in partial remission at the end of treatment. One patient (5%) failed to respond to combined modality therapy. The overall 5 year actuarial survival was 64% and the disease free survival, 55%. Persistent or recurrent disease occurred in 8 patients (40%); one of them was salvaged by surgery and chemotherapy. Site and extent of primary lesion were prognosticators of patients' outcome. One patient developed radiation-related-sequelae. The efficacy of aggressive management consisting of wide surgery, radiotherapy and intermittent high dose chemotherapy is discussed.

journal_name

J Surg Oncol

authors

Ben-Arush M,Kuten A,Perez-Nahum M,Cohen Y,Bialik V

doi

10.1002/jso.2930480110

subject

Has Abstract

pub_date

1991-09-01 00:00:00

pages

51-5

issue

1

eissn

0022-4790

issn

1096-9098

journal_volume

48

pub_type

杂志文章
  • Epidemiology and clinical characteristics of testicular tumors in Saudi Arabia: King Faisal Specialist Hospital and Research Centre experience.

    abstract::The data on 62 patients with germinal testicular tumors seen at King Faisal Specialist Hospital and Research Centre between January 1977 and June 1983 were analyzed to determine the epidemiologic and clinical characteristics of the disease in Saudi Arabia. Fifty-seven patients were Saudis. The geographic distribution ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930350109

    authors: el-Senoussi MA,Bissada NK,el-Akkad S,Bedikian AY,Morcos R,Bull C

    更新日期:1987-05-01 00:00:00

  • Glutathione and phospholipid depletion of liver tumors after arterial ischemia.

    abstract::Breakdown of membrane phospholipids is a causative event leading to irreversible cell injury after ischemia and reperfusion insults, which might be one mechanism leading to liver tumor cell death after repeated arterial ischemia as well. After 2 hr of hepatic dearterialization followed by 30 min of reperfusion tumor p...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/(SICI)1096-9098(199604)61:4<284::AID-JSO11

    authors: Wang LQ,Persson BG,Xu N,Seidegård J,Jeppsson B,Bengmark S

    更新日期:1996-04-01 00:00:00

  • ABO (H) cell surface antigens in benign and malignant parotid neoplasms.

    abstract::Twenty-two inflammatory, benign, or malignant parotid lesions were studied by means of the specific red cell adherence test (SRCA), a modification of the Coombs' mixed cell agglutination reaction. In 22 normal parotid tissues the acinar structures were devoid of red cell agglutination, but it was present in ductal epi...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930240306

    authors: Woltering EA,Tuttle SE,James AG,Sharma HM

    更新日期:1983-11-01 00:00:00

  • Cytodiagnosis of soft tissue tumors.

    abstract::The only acceptable definitive diagnosis of a soft tissue mass is histologic or cytologic examination. In recent years, fine-needle aspiration cytology is used in more and more centers for diagnosis of soft tissue masses. We studied 196 aspiration cytologies performed on soft tissue lesions. Out of these, in 48 cases ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930370307

    authors: Oland J,Rosen A,Reif R,Sayfan J,Orda R

    更新日期:1988-03-01 00:00:00

  • Identification of preoperative factors associated with outcomes following surgical management of intra-abdominal recurrent or metastatic GIST following neoadjuvant tyrosine kinase inhibitor therapy.

    abstract:BACKGROUND:The role of surgical resection in the treatment of patients with metastatic/recurrent gastrointestinal stromal tumors (GIST) is unclear. The aim of this study was to identify preoperative factors associated with oncologic outcomes for recurrent/metastatic GIST after tyrosine kinase inhibitor (TKI) therapy. ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.24988

    authors: Roland CL,Bednarski BK,Watson K,Torres KE,Cormier JN,Wang WL,Lazar AJ,Somaiah N,Hunt KK,Feig BW

    更新日期:2018-04-01 00:00:00

  • p53 protein immunoexpression in esophageal squamous cell carcinoma and adjacent epithelium.

    abstract:BACKGROUND:Immunoreactivity for p53 tumor suppressor gene product is commonly found in human malignancies and some premalignant lesions, but its role in cancer development and its value as a marker of tumor biologic behavior is still unclear. OBJECTIVES:This study was undertaken to assess p53 immunoexpression in esoph...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-9098(199705)65:1<3::aid-jso2>3.

    authors: Chaves P,Pereira AD,Pinto A,Oliveira AG,Queimado L,Gloria L,Cardoso P,Mira FC,Soares J

    更新日期:1997-05-01 00:00:00

  • Improved survival after pulmonary resection of metastatic colorectal carcinoma.

    abstract::While hepatic resection of metastatic colorectal carcinoma is accepted as effective in selected patients, resection of metastases to other solid organs has not gained wide acceptance. We retrospectively reviewed the records of 49 patients who had resection of isolated pulmonary (18 patients) and hepatic (31 patients) ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930430303

    authors: Sauter ER,Bolton JS,Willis GW,Farr GH,Sardi A

    更新日期:1990-03-01 00:00:00

  • Modern reconstructive techniques for abdominal wall defects after oncologic resection.

    abstract::Resection of abdominal wall tumors often leaves patients with debilitating soft tissue defects. Modern reconstructive techniques can be used to restore abdominal wall integrity. In this article, we present an overview of preoperative patient evaluation, analysis of the defect, surgical planning, and the spectrum of av...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.23824

    authors: Khansa I,Janis JE

    更新日期:2015-04-01 00:00:00

  • Macrophage-mediated tumor cytotoxicity: role of macrophage surface sialic acid.

    abstract::Cell surface sialic acid levels were compared for monocytes and macrophages obtained from normal volunteers and breast cancer patients. Equal quantities of sialic acid were found on the monocytes obtained from normal volunteers and breast cancer patients. Approximately 60% more cell surface sialic acid was found on th...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930220203

    authors: Cameron DJ

    更新日期:1983-02-01 00:00:00

  • Nodal stage of stage III colon cancer: the impact of metastatic lymph node ratio.

    abstract:PURPOSE:We assessed which classification of lymph node metastasis better predicted outcomes in patients with colorectal carcinoma. METHODS:We identified 318 patients (176 men) with stage III colon cancer who underwent curative resection. The number of LNs dissected, LNR, and disease-free survival time, were analyzed. ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.21273

    authors: Park IJ,Choi GS,Jun SH

    更新日期:2009-09-01 00:00:00

  • Assessing cosmetic results after breast conserving surgery.

    abstract::"Taking less treating better" has been one of the major improvements of breast cancer surgery in the last four decades. The application of this principle translates into equivalent survival of breast cancer conserving treatment (BCT) when compared to mastectomy, with a better cosmetic outcome. While it is relatively e...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.23596

    authors: Cardoso MJ,Oliveira H,Cardoso J

    更新日期:2014-07-01 00:00:00

  • Impact of specific modes of circumferential resection margin involvement in rectal cancer local recurrence: A retrospective study.

    abstract:PURPOSE:To compare the local recurrence rate and overall survival between patients with circumferential resection margin (CRM) involvement by direct tumor spread and by a tumor within a lymph node. METHODS:A total of 776 patients diagnosed with rectal cancer underwent rectal resection. Patients with CRM involvement by...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.25252

    authors: Suárez J,Goicoetxea A,Gómez ML,Jiménez G,Llanos MC,Jiménez J,Montes B,de Miguel M

    更新日期:2018-12-01 00:00:00

  • Modified radical lymphadenectomy without splenectomy in patients with proximal gastric cancer: comparison with standard D2 lymphadenectomy for distal gastric cancer.

    abstract:BACKGROUND AND OBJECTIVES:We assessed the optimal extent of lymph node dissection and the effect of splenectomy in patients with proximal gastric cancer. METHOD:Recurrence and survival rates were compared between 881 patients with proximal gastric cancer who underwent modified radical lymphadenectomy and 3,098 patient...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.21137

    authors: Cheong O,Kim BS,Yook JH,Oh ST,Park YK,Ryu SY

    更新日期:2008-12-01 00:00:00

  • Clinicopathologic characteristics and prognosis of mucinous gastric carcinoma.

    abstract:BACKGROUND AND OBJECTIVES:Reports of clinicopathological features and prognosis in patients with mucinous gastric carcinoma (MGC) are conflicting. The aim was to describe the clinicopathological features and prognosis of patients with MGC in comparison with nonmucinous gastric carcinoma (NMGC). METHODS:We reviewed the...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.21533

    authors: Zhang M,Zhu GY,Zhang HF,Gao HY,Han XF,Xue YW

    更新日期:2010-07-01 00:00:00

  • Nutritional status in advanced upper gastrointestinal cancer.

    abstract::Fifty-four patients with advanced upper gastrointestinal cancer were assessed for their nutritional status prior to any form of therapy. Anthropometric parameters--weight loss, arm muscle circumference, skin-fold thickness--and biochemical parameters--serum albumin and delayed cutaneous hypersensitivity reactions to p...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930290417

    authors: Singh G,Khanna NN

    更新日期:1985-08-01 00:00:00

  • A cardiogastric fistula after gastric tube interposition. A case report and review of literature.

    abstract::A patient is presented with massive hematemesis caused by a fistula between the left cardiac atrium and a gastric tube interposition, which was constructed after esophagectomy for esophageal cancer 3 years earlier. ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.20432

    authors: Schouten van der Velden AP,Ruers TJ,Bonenkamp JJ

    更新日期:2007-01-01 00:00:00

  • Synovial sarcoma of the abdominal wall: a case report and study of its fine structure.

    abstract::A case of synovial sarcoma in the abdominal wall of a 50-year-old Iraq female is reported. The ultrastructure of the tumor has been studied. Eight other cases of synovial sarcoma in the abdominal wall which reported in the English literature up to 1978 have been reviewed. Synovial sarcomas in the abdominal wall tend t...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930180403

    authors: Al-Dewachi HS,Sangal BC,Zakaria MA

    更新日期:1981-01-01 00:00:00

  • Local recurrence rate of fine-needle aspiration biopsy in primary high-grade sarcomas.

    abstract:BACKGROUND:Fine-needle aspiration biopsy (FNAB) is an emerging technique for diagnosis of bone and soft tissue lesions. While multiple studies have demonstrated efficacy, cost-effectiveness, and convenience, none have attempted to determine if the modality leads to an increased rate of local recurrence. Our objective w...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.21552

    authors: Kaffenberger BH,Wakely PE Jr,Mayerson JL

    更新日期:2010-06-01 00:00:00

  • Prognostic utility of albumin-bilirubin grade for short- and long-term outcomes following hepatic resection for intrahepatic cholangiocarcinoma: A multi-institutional analysis of 706 patients.

    abstract:BACKGROUND:The objective of the current study was to define the impact of albumin-bilirubin (ALBI) grade on short- as well as long-term outcomes among patients with intrahepatic cholangiocarcinoma (ICC). METHODS:Patients who underwent hepatectomy for ICC between 1990 and 2016 were identified using an international mul...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,多中心研究

    doi:10.1002/jso.25486

    authors: Tsilimigras DI,Hyer JM,Moris D,Sahara K,Bagante F,Guglielmi A,Aldrighetti L,Alexandrescu S,Marques HP,Shen F,Koerkamp BG,Endo I,Pawlik TM,other members of the International Intrahepatic Cholangiocarcinoma Study Group.

    更新日期:2019-08-01 00:00:00

  • Radiation therapy for advanced and metastatic melanoma.

    abstract::Radiation therapy (RT) is an important modality in cancer treatment. However, the general perception is that melanoma is radio-resistant. High quality clinical trials are helping to establish the place of RT in select scenarios of advanced disease at primary, regional, and distant sites. New RT techniques need to be i...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.23509

    authors: Fogarty GB,Hong A

    更新日期:2014-03-01 00:00:00

  • Postoperative complications are associated with poor survival outcome after curative resection for colorectal cancer: A propensity-score analysis.

    abstract:OBJECTIVE:We retrospectively evaluated the impact of postoperative complications on long-term outcomes after curative resection for colorectal cancer (CRC), using propensity-score analysis (PSA). PATIENTS AND METHODS:We reviewed data from 673 consecutive patients with stage I to III CRC, who underwent curative resecti...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.25961

    authors: Miyamoto Y,Hiyoshi Y,Tokunaga R,Akiyama T,Daitoku N,Sakamoto Y,Yoshida N,Baba H

    更新日期:2020-08-01 00:00:00

  • Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: Technical considerations and the learning curve.

    abstract::Over the past decade, there has been a considerable increase in the utilization of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) in the management of patients with peritoneal metastases. This is due to improved safety and favorable oncologic outcomes, including curative potential. C...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.25939

    authors: Vining CC,Izquierdo F,Eng OS,Turaga KK

    更新日期:2020-07-01 00:00:00

  • Comparative analysis of imaging modalities in the preoperative assessment of nodal metastasis in esophageal cancer.

    abstract::Preoperative radiological findings of nodal status in 74 patients, using endoscopic ultrasonography (EUS), computed tomography (CT), ultrasonography (US), and magnetic resonance imaging (MRI), were compared to histopathology reports following transthoracic total esophagectomy with radical lymphadenectomy (TTE), involv...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/(SICI)1096-9098(199603)61:3<214::AID-JSO10

    authors: Chandawarkar RY,Kakegawa T,Fujita H,Yamana H,Hayabuthi N

    更新日期:1996-03-01 00:00:00

  • Introduction: Role of palliative care for the surgical patient.

    abstract::Palliative care (PC) seeks to improve the quality of life for patients facing serious illness. Several oncology organizations have guidelines about PC, reflecting the need to integrate PC into standard oncology care. Many surgical patients do not receive PC despite the need for these services and established surgical ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.25449

    authors: Fahy BN

    更新日期:2019-07-01 00:00:00

  • Comparison of open and closed abdomen techniques for the delivery of intraperitoneal pemetrexed using a murine model.

    abstract:BACKGROUND AND OBJECTIVES:Pemetrexed is an appealing agent to use for cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC). However, the optimal method of pemetrexed delivery still remains undefined. Using a murine model, we compared the use of open and closed abdomen techniques on the absorptio...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.24960

    authors: Badrudin D,Sideris L,Perrault-Mercier C,Hubert J,Leblond FA,Dubé P

    更新日期:2018-05-01 00:00:00

  • Rapid and accurate method for delineating cancer lesions in laparoscopic colectomy using activated carbon injection.

    abstract::The aim of our study was to evaluate the clinical efficacy of preoperative injection of activated carbon in delineation of cancer location in laparoscopic colectomy. Activated carbon particles were injected during endoscopy into the normal colonic wall surrounding cancer lesions in five cases of early colon cancer, pr...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930580107

    authors: Kitamura K,Yamane T,Oyama T,Shimotsuma M,Hagiwara A,Yamaguchi T,Sawai K,Takahashi T

    更新日期:1995-01-01 00:00:00

  • Serological evaluation of human brain tumors using a microradioisotopic staphylococcal protein A assay.

    abstract::A microradioisotopic staphylococcal protein A assay was applied to the serological evaluation of preoperative sera from brain tumor patients. The assay was performed in Terasaki plates, and a stainless steel punch and multiholed die facilitated sample prearation. Using allogeneic astrocytoma target cells, 15/19 of the...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930140306

    authors: Cohen AM,Wood WC

    更新日期:1980-01-01 00:00:00

  • National quality measurement using clinical indicators: the Danish National Indicator Project.

    abstract::This article describes the Danish National Indicator Project that aims to document and improve the quality of care at national level. Specific clinical indicators, standards, and prognostic factors have been developed for eight diseases (e.g. lung cancer). It has been implemented in all clinical departments in Denmark...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.21192

    authors: Mainz J,Hansen AM,Palshof T,Bartels PD

    更新日期:2009-06-15 00:00:00

  • Autologous transfusions for cancer patients undergoing elective ablative surgery.

    abstract::Patients who have cancer are exposed to the adverse consequences of blood transfusions, such as transmissible diseases. This study presents an examination of a program of autologous blood deposit for cancer patients undergoing elective surgical procedures. Over a 3-year period, 235 patients deposited 388 units of auto...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930430106

    authors: Lichtiger B,Huh YO,Armintor M,Fischer HE

    更新日期:1990-01-01 00:00:00

  • Indications and techniques for robotic pelvic and para-aortic lymphadenectomy in gynecologic oncology.

    abstract::Robotic-assisted laparoscopy is now the most common surgical method for treatment of early-stage endometrial, cervical, and a growing number of ovarian cancers in the U.S. Para-aortic and pelvic lymphadenectomy is integral to surgical staging and subsequent treatment planning. This article reviews current staging outc...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.24005

    authors: Wisner KP,Gupta S,Ahmad S,Holloway RW

    更新日期:2015-12-01 00:00:00