Abstract:
:Most surgical oncologists receive exposure to clinical studies in their fellowships; however they receive little if any practical knowledge as to how to become a clinical researcher. This article will provide a broad introduction to setting up a community based surgical oncology research program with emphasis on the practical issues necessary to be successful. Topics to be discussed include choosing appropriate studies, setting up the team, IRB issues, financial concerns, helpful hints for enrolling patients, and much more. Getting a program going can seem daunting but ultimately will be very rewarding for both the surgeon and their patients.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Beitsch P,Huber Tdoi
10.1002/jso.21780subject
Has Abstractpub_date
2011-09-01 00:00:00pages
447-51issue
4eissn
0022-4790issn
1096-9098journal_volume
104pub_type
杂志文章,评审abstract::We report a case of pancreatic sarcoidosis in a patient with radiographic and clinical findings suggestive of pancreatic cancer. Clinically apparent involvement of the pancreas is uncommon in patients with known sarcoidosis and is distinctly unusual as the initial presentation of disease. Sarcoid involvement of the pa...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.2930540215
更新日期:1993-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Neoadjuvant chemotherapy (nCMT) has been increasingly used in advanced gastric cancer (GC). However, the prognostic impact of tumor response remains unclear. This study aimed to evaluate if tumor response at the primary site and lymph nodes (LN) correlate with survival in GC patients after nCMT...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25785
更新日期:2020-04-01 00:00:00
abstract::A longitudinal osteotomy of lateral sacrum for malignant iliac tumors using modified threadwire saw is conducted. This procedure issignificantly wide, rapid and safe. ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20646
更新日期:2007-03-01 00:00:00
abstract::Responsiveness of experimental chemotherapy on human cancer xenografts in nude mice was directly compared with clinical response to the same chemotherapy in their donor patients. These xenografts were 1 line of rectal cancer (H-26), two lines of gastric cancer (H-08 and H-22), and 1 line of breast cancer (H-62). Exper...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930150304
更新日期:1980-01-01 00:00:00
abstract::A case of vulvar carcinoma with 0.5 mm of invasion treated by radical wide local excision only, which later developed ipsilateral inguinal lymph node recurrence, is presented. This represents the least amount of invasion reported resulting in inguinal lymph node metastasis. Review of the literature of stage I vulvar c...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930540418
更新日期:1993-12-01 00:00:00
abstract::Patients with peritoneal carcinomatosis (PC) from colorectal origin may undergo cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) as a curative approach. One major prognostic factor that affects survival is completeness of cytoreduction. Molecular Fluorescence Guided Surgery (MFGS) is ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.25106
更新日期:2018-08-01 00:00:00
abstract::The relationship of acute appendicitis occurring previous to cancer in colon and rectum was studied in the consecutive records of 561 patients, of 40 years of age and older, operated upon with an appendectomy because of acute appendicitis. Sixteen (2.9%) of these patients were readmitted within three years because of ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930200105
更新日期:1982-05-01 00:00:00
abstract::Among women who have undergone surgery for breast cancer, the risk of recurrence, especially distant metastases, peaks 1-2 years postsurgery. Recent clinical trial evidence suggests that initial adjuvant therapy with an aromatase inhibitor (AI) can reduce this early risk of recurrence. According to the recently update...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.21801
更新日期:2011-06-01 00:00:00
abstract::From 1974 to 1985, 161 patients were followed by at least one colonoscopy following a polypectomy for an adenomatous polyp. These patients had had a previous curative resection performed for colorectal carcinoma. The median follow-up time after surgery was 54 months. A polyp within 65 cm from the anal verge or from a ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930380204
更新日期:1988-06-01 00:00:00
abstract::A total of 144 patients with advanced sarcomas were entered into a randomized prospective protocol with four treatment arms utilizing different combinations of chemotherapeutic agents. Of these, 120 patients (83%) were judged acceptable. Treatment 1: actinomycin-D (Act-D), 0.01 mg/kg IV, days 1--5; phenylalanine must...
journal_title:Journal of surgical oncology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/jso.2930110406
更新日期:1979-01-01 00:00:00
abstract::The present study has investigated whether Kaposi's sarcoma (KS) in Nigeria is associated with infection with the AIDS virus variously called human T-cell lymphotropic virus type III (HTLV-III), lymphadenopathy/AIDS virus (LAV), and AIDS-associated retrovirus (ARV). Serum samples from 40 KS patients, 30 patients with ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930370303
更新日期:1988-03-01 00:00:00
abstract:BACKGROUND:Evidence regarding the prognostic value of perineural invasion (PNI) in oral squamous cell carcinoma (OSCC) and whether PNI alone warrants consideration of adjuvant therapy is controversial. We evaluated whether histopathological sub-categorization of PNI improves risk stratification. METHODS:PNI was evalua...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23821
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Soft tissue sarcomas of the head and neck (STSHN) comprise a rare group of malignancies. Our objective is to determine the utility of soft tissue sarcoma staging systems within the head and neck, and to validate an individualized soft tissue sarcoma nomogram within head and neck primary sites....
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23868
更新日期:2015-05-01 00:00:00
abstract::Three patients with unresectable malignant retroperitoneal tumors that invaded and perforated the distal duodenum presented with sepsis unresponsive to antibiotics. A technique of proximal side-to-side duodenojejunostomy with stapled occlusion of the distal duodenum resulted in successful diversion and immediate resol...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930260410
更新日期:1984-08-01 00:00:00
abstract:BACKGROUND:Locally advanced colon cancer can result in serious clinical conditions unless treated appropriately. The aim of this study was to examine the feasibility of en bloc resection and the significance of depth of invasion by analyzing the outcomes of the procedure in colon cancer invading adjacent organs. METHO...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21165
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:There is currently debate about the optimal timing and frequency of mammography follow-up after breast-conserving therapy (BCT). The purpose of this study was to determine if 6-month intervals for the first 2 years following BCT offer benefit over annual screening. METHODS:Three hundred ninet...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23298
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The single-arm ROSiA study evaluated frontline bevacizumab for advanced ovarian cancer. We explored how discordant surgically and radiologically assessed postoperative residual disease affects outcomes. METHODS:After debulking surgery, 1021 patients received 4 to 8 cycles of carboplatin-pacli...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25647
更新日期:2019-09-01 00:00:00
abstract::Twenty-two inflammatory, benign, or malignant parotid lesions were studied by means of the specific red cell adherence test (SRCA), a modification of the Coombs' mixed cell agglutination reaction. In 22 normal parotid tissues the acinar structures were devoid of red cell agglutination, but it was present in ductal epi...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930240306
更新日期:1983-11-01 00:00:00
abstract::Although the radioreceptor method is widely used for estrogen receptor assay in human tissue, it has several limitations and a number of alternative methods are being explored. An immunohistochemical method of estrogen receptor assay using a specific antibody to estradiol has been proposed as a suitable alternative. T...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930330206
更新日期:1986-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Uncertainty exists about the value of cancer therapy in patients aged 90 years and older. Because of the relative paucity of these patients, as well as the possibility of selection bias in any one institution, the use of a large, total population-based cancer registry was employed. METHODS:Th...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.10160
更新日期:2002-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:In highly selected patients with peritoneal carcinomatosis, cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) can be an aggressive but worthwhile treatment regimen. Resection of the rectosigmoid is frequently performed with CRS. The aim of the study wa...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25189
更新日期:2018-09-01 00:00:00
abstract::The main objective of this study was to differentiate between lymph nodes infiltrated by estrogen receptor-positive (ER+) and estrogen receptor-negative (ER-) breast carcinoma. Lymph nodes were obtained from 40 postmenopausal cancer patients, 10 from each disease stage. Six patients from each group had estrogen recept...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930400107
更新日期:1989-01-01 00:00:00
abstract::Leiomyosarcoma of the colon is a rare neoplasm. It is widely known that primary malignant lesions may present either simultaneously (synchronous tumor) or at different times (metachronous tumor). The incidence of metachronous colonic mucosal carcinoma is generally considered to range from 3 to 5%. Metachronous leiomyo...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930320403
更新日期:1986-08-01 00:00:00
abstract:INTRODUCTION:The Siewert classification has been used to plan treatment for tumours of the gastro-oesophageal junction since its proposal in the 1980s. The purpose of this study was to assess its continued relevance by evaluating whether there were differences in the biology and clinical characteristics of adenocarcino...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23484
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:One of the reasons for the poor prognosis of pancreatic carcinoma is the difficulty of obtaining an early diagnosis of pancreatic carcinoma. One possibility is the application of radioimmunoscintigraphy using radiolabeled monoclonal antibodies (Mabs). METHODS:We labeled chimeric (human/mouse) Fab fragments ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.10311
更新日期:2003-11-01 00:00:00
abstract:BACKGROUND:Rapid genetic counseling and testing (RGCT) in newly diagnosed high-risk breast cancer (BC) patients may influence surgical treatment decisions. To successfully integrate RGCT in practice, knowledge of professionals', and patients' attitudes toward RGCT is essential. METHODS:Between 2008 and 2010, we perfor...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24763
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVE:To propose a distinct anatomical classification for the superior thyroid pole that may serve as a surgical landmark and could help reduce complications in thyroid surgery. MATERIALS AND METHODS:A comprehensive anatomical study based on existing literature and surgical observations. RESULTS:The proposed supe...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23950
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:The aim of this study is to describe the influence of geography, socio-economic development, and demographic shift on the trends in global incidence, mortality, and prevalence of liver cancer (LC). METHODS:Data (2012-2030) relating to LC and demographic shifts based on WHO regions and HDI areas were extract...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24518
更新日期:2017-04-01 00:00:00
abstract::A case of renal cell carcinoma arising in a horseshoe kidney and presenting with a pathologic fracture of humerus is reported. Relevant literature is discussed. ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930260116
更新日期:1984-05-01 00:00:00
abstract::Three patients treated with bilateral subcutaneous mastectomies and implants for fibrocystic disease or carcinoma in situ subsequently developed invasive breast carcinoma. These cases emphasize that subcutaneous mastectomy does not prevent the development of breast cancer. If the circumstances in an individual patient...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930260313
更新日期:1984-07-01 00:00:00