Abstract:
BACKGROUND AND OBJECTIVES:Soft tissue sarcomas of the head and neck (STSHN) comprise a rare group of malignancies. Our objective is to determine the utility of soft tissue sarcoma staging systems within the head and neck, and to validate an individualized soft tissue sarcoma nomogram within head and neck primary sites. METHODS:Previously-untreated patients with STSHN diagnosed and treated between 1982 and 2012 were eligible (n = 319, median follow-up 46 months). Clinical variables were extracted from a prospectively-maintained database. The performance of AJCC/UICC and MSK staging systems and a soft tissue sarcoma-specific nomogram were assessed. RESULTS:Four-year overall survival (OS), disease specific survival (DSS), and recurrence-free survival (RFS) were 72%, 76%, and 71%, respectively. AJCC/UICC and MSK staging systems accurately stratified outcomes (OS, DSS, and RFS; P < 0.001 for all comparisons). The nomogram stratified outcomes by quartile (P < 0.001), and predicted risk of death at 4, 8 and 12 years (P < 0.001). Concordance indices for overall survival for the AJCC/UICC system, MSK system, and the nomogram were 0.71, 0.70, and 0.78, respectively. CONCLUSIONS:Oncologic outcomes among groups of patients with STSHN can be accurately predicted using both the AJCC/UICC and MSK staging systems. A soft tissue sarcoma-specific nomogram provides reliable, individualized prognostic information for patients with STSHN.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Shuman AG,Brennan MF,Palmer FL,Kuk D,Moraco N,Singer S,Shah JP,Patel SGdoi
10.1002/jso.23868subject
Has Abstractpub_date
2015-05-01 00:00:00pages
690-5issue
6eissn
0022-4790issn
1096-9098journal_volume
111pub_type
杂志文章abstract::The sentinel node (SN) is defined as the first draining node from the primary lesion and it has proven to be a good indicator of the metastatic status of regional lymph nodes in solid tumors. In the past 5 years, the validity of SN concept for gastric cancer has been demonstrated by a number of single institutional st...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.20220
更新日期:2005-06-01 00:00:00
abstract:PURPOSE:We assessed which classification of lymph node metastasis better predicted outcomes in patients with colorectal carcinoma. METHODS:We identified 318 patients (176 men) with stage III colon cancer who underwent curative resection. The number of LNs dissected, LNR, and disease-free survival time, were analyzed. ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21273
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:To determine the prognostic significance of the colposcopic tumor size in the management of cervical cancer. METHODS:Clinicopathological analysis was performed in 751 consecutive patients with stage IB squamous cervical cancer who were surgically treated in a single institute. The colposcopic...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/1096-9098(200102)76:2<133::aid-jso1024>3.0
更新日期:2001-02-01 00:00:00
abstract:BACKGROUND:Randomized controlled trials have demonstrated comparable survival outcomes for short-course (SCRT) and long-course neoadjuvant radiotherapy (LCRT) in patients with rectal cancer. METHODS:Using the National Cancer Data Base (2004-2015), a propensity score was used to match 188 patients with rectal cancer re...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25355
更新日期:2019-03-01 00:00:00
abstract::We studied survival and prognostic factors in all cases of hepatocellular carcinoma seen at a Midwestern teaching hospital from 1947 through 1986. Of the 70 cases, 56 were diagnosed during life and 14 at autopsy. There were 47 males and 23 females with age at diagnosis ranging from 14 to 88. Median survival for the 56...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930450409
更新日期:1990-12-01 00:00:00
abstract::A prospective randomized phase III trial was carried out at Songklanagarind Hospital from August 1988 to December 1990. The objectives of the study were to evaluate the effect of chemotherapy regimen in squamous cell carcinoma of the esophagus and to determine whether induction chemotherapy improves symptom-free perio...
journal_title:Journal of surgical oncology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/jso.2930560314
更新日期:1994-07-01 00:00:00
abstract::Cryotechnology is currently used for both treatment and diagnosis of breast disease. Due to the natural analgesic effect of cold, cryoablation is potentially more patient-friendly than other technologies which raise tissue temperature. Freezing produces a predictable volume of necrosis and is easily observed and contr...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.20201
更新日期:2005-04-01 00:00:00
abstract::Supernatant fluids from three human cultured cell lines, K562, NALM-1, and Daudi, all isolated from patients with lymphoreticular malignancies, were tested for suppressive activity toward normal lymphocytes in vitro. It was found that the K562 line elaborated material which effectively suppressed the response of norma...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930230106
更新日期:1983-05-01 00:00:00
abstract:INTRODUCTION:Alpha-fetoprotein (AFP) has a valuable role in postoperative surveillance for hepatocellular carcinoma (HCC) recurrence. The utility of pretreatment or baseline AFP remains controversial. The present study hypothesized that elevated baseline AFP levels are associated with worse overall survival in HCC pati...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24742
更新日期:2017-12-01 00:00:00
abstract::To compare toxicity and efficacy of both salvage prostatectomy and salvage radiotherapy for prostate cancer a retrospective analysis was conducted. Thirty-two and 41 patients were treated with external beam radiotherapy or prostatectomy for cT1c-T2 prostate cancer later requiring salvage surgery or radiotherapy. Salva...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20967
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:It is unclear if a specific strategy for simultaneous treatment of primary thymic neoplasms and pleural metastases confers benefit for Masaoka stage IVA disease. We reviewed our experience with thymic neoplasms with concurrent pleural metastases to identify factors influencing outcomes. METHO...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25981
更新日期:2020-09-01 00:00:00
abstract::The records of 111 consecutive cases of carcinoma of the breast were reviewed and yielded 66 patients who had undergone liver scanning and determination of the serum alkaline phosphatase (alk p'tase), lactic dehydrogenase (LDH), and serum glutamic oxaloacetic transaminase (SGOT). Four of the 66 patients (6.1%) had a f...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930130313
更新日期:1980-01-01 00:00:00
abstract:BACKGROUND:Cytoreductive surgery (CRS) and hyperthermic intra-peritoneal chemotherapy (HIPEC) treatment of colorectal peritoneal metastases (PM) is an established treatment alternative. The study aim was, first, to investigate the outcome of high-volume disease defined by the peritoneal cancer index (PCI) 20; second, t...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23610
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND:Hepatic arterial infusion chemotherapy (HAIC) has been recognized as one of the effective treatments for patients with hepatic metastatic tumor. However it is difficult to perform HAIC in the long term without complications. This report describes the laparotomic approach using the side holed catheter, which ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20283
更新日期:2005-08-01 00:00:00
abstract:BACKGROUND:The three-delays model describes delays in seeking, reaching, and receiving care for vulnerable populations needing treatment. The dominant delay for patients with gastric adenocarcinoma (GAC) is unknown. We aimed to define patients with GAC who reached and received care at our regional safety-net hospital (...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25299
更新日期:2019-01-01 00:00:00
abstract::Ten patients with Stage III-IV ovarian adenocarcinoma were treated with the drug combination etoposide (VP-16) plus cisplatin (DDP). All patients were in relapse following prior vigorous, uninterrupted treatment with three or more lines of chemotherapy that included (1) courses of weekly 1-mg/kg single-agent DDP, (2) ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930320112
更新日期:1986-05-01 00:00:00
abstract::We studied the influence of surgical trauma to the iliac bone on the implantation of I.V. injected tumor cells, which formed tumor in the surgical wounds of 27/84 mice (32%). None of these mice or nonsurgical mice developed tumor in the opposite or uninjured pelvic bone (P < 0.0001). When different numbers (10(5), 5 x...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930560311
更新日期:1994-07-01 00:00:00
abstract:OBJECTIVE:We investigate the neutrophil to lymphocyte ratio (NLR) as a potential prognostic factor for patients undergoing curative liver resection for colorectal liver metastasis (CRLM). METHODS:We identified patients who underwent liver resection, via our prospectively accumulated surgical database at the Royal Mars...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23845
更新日期:2015-03-15 00:00:00
abstract::Of 134 patients with thymoma, 79 (59%) also had myasthenia gravis (MG). The thymoma with MG differed from that in the absence of MG in the following aspects: The ratio of lymphocytes to epithelial cells in the tumor was larger, the polygonal cell type was more prominent (i.e., in 83% of the MG patients this cell type ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930380305
更新日期:1988-07-01 00:00:00
abstract::Mucin-producing tumors of the pancreas (MPT) are characterized by the production of much mucin and a benign course after surgical treatment. We examined 16 cases of MPT and 20 cases of "common" pancreatic duct cell carcinomas (DCC) in regard to K-ras and p53 mutations. The mutations were detected by constant denaturan...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930550205
更新日期:1994-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Tumor thickness is considered the single most important predictor of survival in clinically localized malignant melanoma. A recent study found tumor volume a more sensitive predictor of survival than thickness. Volume measurement, however, is complicated, time consuming, and based on biologica...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9098(199810)69:2<83::aid-jso7>3
更新日期:1998-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Hyaluronic acid binding protein 1 (HABP1), a family of proteins interacting with hyaluronan (HA), had been associated with cell adhesion and tumor invasion. The aim of this study was to investigate the correlation between clinicopathologic factors and patient survival time with the expression ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21329
更新日期:2009-10-01 00:00:00
abstract::A jaundiced patient due to inoperable bile duct carcinoma was treated by a combination of surgery, radiotherapy, and chemotherapy. At the operation an intra-abdominal, extra-choledochal bypass of the tumor was performed with a T-tube obstruction 10 months after diagnosis, and no evidence of malignancy was seen. The T-...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930130308
更新日期:1980-01-01 00:00:00
abstract:BACKGROUND:Retroperitoneal lymphangiomatosis (RL) is a rare form of primary lymphedema featuring aberrant retroperitoneal lymphatic proliferation. It causes recurrent cellulitis, repeated interventions, and poor life quality. This study aimed to investigate proper diagnositc criteria and surgical outcomes for RL with e...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25514
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Alterations in mitochondrial DNA have been identified in a number of solid tumor types, including gastric, head and neck, breast, colorectal, lung, and bladder carcinomas. Recently, a homopolymeric C stretch (D310) located within the noncoding D-loop of the mitochondrial genome was identified and described a...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.10202
更新日期:2003-03-01 00:00:00
abstract::Early postoperative intraperitoneal chemotherapy (EPIC) and intraoperative peritoneal hypertermic chemotherapy (IPHC) are used in addition with cytoreductive surgery to treat with curative intent peritoneal carcinomatosis arising from colorectal adenocarcinomas. Three patients with such a disease were treated with per...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20267
更新日期:2005-07-01 00:00:00
abstract::A 29-year-old female was diagnosed with a symptomatic, extra-abdominal desmoid tumor during the first trimester of pregnancy. Computerized tomography (CT) and transabdominal ultrasound (US) noted a mass within the left rectus sheath measuring up to 15 cm in greatest diameter, with mild compression of the uterus. Preop...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20189
更新日期:2005-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:This analysis aims to evaluate the value of early surveillance within 6 months after resection for stage II/III colorectal cancer (CRC). METHODS:Patients with stage II/III CRC who received surgery with curative intent for CRC were included. CT scans of the chest, abdomen, and pelvis performed...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23432
更新日期:2013-12-01 00:00:00
abstract::Mice with intravesical urothelial tumors (MBT-2) were challenged with E coli inoculated intravesically. Adherence of bacteria measured at 15 min or persistent infection at 24 h was significantly greater in the tumor-bearing bladders than in normal non-tumor-bearing mice. The tumor-bearing portion of the bladder contai...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930230405
更新日期:1983-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The most common cause of failure in large segment bone allografts used for oncologic reconstruction is allograft fracture. Reinforcement with pressurized intramedullary cement may improve the mechanical properties of allografts. METHODS:We reviewed the prospectively collected records of 45 pa...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.10316
更新日期:2003-12-01 00:00:00