Abstract：
BACKGROUND:Rapid genetic counseling and testing (RGCT) in newly diagnosed high-risk breast cancer (BC) patients may influence surgical treatment decisions. To successfully integrate RGCT in practice, knowledge of professionals', and patients' attitudes toward RGCT is essential. METHODS:Between 2008 and 2010, we performed a randomized clinical trial evaluating the impact of RGCT. Attitudes toward and experience with RGCT were assessed in 265 patients (at diagnosis, 6- and 12-month follow-up) and 29 medical professionals (before and after the recruitment period). RESULTS:At 6-month follow-up, more patients who had been offered RGCT felt they had been actively involved in treatment decision-making than patients who had been offered usual care (67% vs 48%, P = 0.06). Patients who received DNA-test results before primary surgery reported more often that RGCT influenced treatment decisions than those who received results afterwards (P < 0.01). Eighty-seven percent felt that genetic counseling and testing (GCT) should preferably take place between diagnosis and surgery. Most professionals (72%) agreed that RGCT should be routinely offered to eligible patients. Most patients (74%) and professionals (85%) considered surgeons the most appropriate source for referral. CONCLUSIONS:RGCT is viewed as helpful for newly diagnosed high-risk BC patients in choosing their primary surgery and should be offered routinely by surgeons.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Wevers MR,Aaronson NK,Bleiker EMA,Hahn DEE,Brouwer T,van Dalen T,Theunissen EB,van Ooijen B,de Roos MA,Borgstein PJ,Vrouenraets BC,Vriens E,Bouma WH,Rijna H,Vente JP,Kuenen MA,van der Sanden-Melis J,Witkamp AJ,Rutgersdoi
10.1002/jso.24763subject
Has Abstractpub_date
2017-12-01 00:00:00pages
1029-1039issue
8eissn
0022-4790issn
1096-9098journal_volume
116pub_type
杂志文章abstract：BACKGROUND:Recurrent pleomorphic adenoma (PA) of the parotid gland is a challenging surgical issue with controversy regarding management and long term outcome. METHODS:All patients who were operated for recurrent PA of the parotid gland between the years 1991 and 2013 were reviewed. Patient demographics, clinicopathol...
journal_title：Journal of surgical oncology
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更新日期：2016-11-01 00:00:00
abstract：OBJECTIVE:Significant controversy exists concerning the factors affecting survival after secondary cytoreduction (SCR) in recurrent ovarian cancer. This study aims to identify factors independently associated with survival after SCR. METHODS:We retrospectively retrieved 39 patients with recurrent ovarian cancer. All p...
journal_title：Journal of surgical oncology
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更新日期：2010-11-01 00:00:00
abstract：:Although the radioreceptor method is widely used for estrogen receptor assay in human tissue, it has several limitations and a number of alternative methods are being explored. An immunohistochemical method of estrogen receptor assay using a specific antibody to estradiol has been proposed as a suitable alternative. T...
journal_title：Journal of surgical oncology
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doi：10.1002/jso.2930330206
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abstract：:Do age, associated diseases, general state, or the stage of tumor determine the operability of breast cancer in the elderly? Risk factors are studied on the basis of data on 465 patients over 70 years of age who had breast cancer surgery between 1977 and 1986. Operative mortality of patients is analyzed, and according...
journal_title：Journal of surgical oncology
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doi：10.1002/jso.2930410108
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abstract：BACKGROUND:A person-centered approach to co-decision-making using tailored information respects each woman's preferences and may heighten breast reconstruction satisfaction. METHODS:Women seeking breast reconstruction underwent initial and follow-up consultations wherein suitable options were discussed, and take-away ...
journal_title：Journal of surgical oncology
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更新日期：2014-12-01 00:00:00
abstract：:Thirty-five consecutive patients underwent en bloc resection of cardia cancer without thoracotomy. All tumors were adenocarcinoma. The operative procedure involved wide resection of the peri-hiatal diaphragm, dissection of the upper abdominal and lower mediastinal lymph nodes, and resection of the stomach including a ...
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更新日期：2012-12-01 00:00:00
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journal_title：Journal of surgical oncology
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更新日期：2017-11-01 00:00:00
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journal_title：Journal of surgical oncology
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更新日期：2018-06-01 00:00:00
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journal_title：Journal of surgical oncology
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更新日期：2008-01-01 00:00:00
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更新日期：1988-10-01 00:00:00
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更新日期：2020-09-01 00:00:00
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journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.21084
更新日期：2008-09-15 00:00:00
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journal_title：Journal of surgical oncology
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doi：10.1002/jso.2930290417
更新日期：1985-08-01 00:00:00
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journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.2930080212
更新日期：1976-01-01 00:00:00
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journal_title：Journal of surgical oncology
pub_type： 杂志文章,评审
doi：10.1002/jso.23798
更新日期：2015-03-01 00:00:00
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journal_title：Journal of surgical oncology
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doi：10.1002/jso.23672
更新日期：2014-09-01 00:00:00
abstract：:A new simplified system for updating a cancer registry has been developed in the Biostatistics Department of Roswell Park Memorial Institute. It was designed to serve the needs of maintaining a registry for a cooperative cancer research group. The Data-Update Procedure at a Remote Terminal (DUPART) system has general ...
journal_title：Journal of surgical oncology
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doi：10.1002/jso.2930070508
更新日期：1975-01-01 00:00:00
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更新日期：2006-02-01 00:00:00
abstract：:Neoadjuvant systemic breast cancer therapy is the administration of systemic therapy to eligible breast cancer patients prior to surgery. This treatment modality was developed out of necessity to downstage inoperable tumors, but it has evolved into a tool for breast conservation surgery. The neoadjuvant approach is al...
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更新日期：2019-07-01 00:00:00
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更新日期：2019-08-01 00:00:00
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journal_title：Journal of surgical oncology
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doi：10.1002/jso.24287
更新日期：2016-08-01 00:00:00
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journal_title：Journal of surgical oncology
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更新日期：2019-11-22 00:00:00
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journal_title：Journal of surgical oncology
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更新日期：1984-05-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Long noncoding RNAs (lncRNAs) play key roles in carcinoma metastasis. We aimed to investigate lncRNA LINC01133 in oral squamous cell carcinoma (OSCC) metastasis. METHODS:The RNA levels of LINC01133 and growth and differentiation factor 15 (GDF15) in tissue samples from OSCC patients, and OSCC...
journal_title：Journal of surgical oncology
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doi：10.1002/jso.25278
更新日期：2018-12-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:When performed at select centers, minimally invasive gastrectomy (MIG) for gastric adenocarcinoma is associated with reduced perioperative morbidity, and similar oncologic outcomes as compared to open gastrectomy (OG). Utilization of, and outcomes associated with, MIG in the United States have...
journal_title：Journal of surgical oncology
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doi：10.1002/jso.24052
更新日期：2015-11-01 00:00:00
abstract：:Prognostic significance of blood vessel invasion in carcinoma of the female breast has been evaluated by study of 242 cases of radical mastectomy done at the Tata Memorial Hospital. The significance of axillary node involvement with the disease has been simultaneously evaluated. In the absence of blood vessel invasion...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.2930090613
更新日期：1977-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:The effects of isolated metastatic node dissection in the para-aortic region have not been established in colorectal cancer (CRC). The authors undertook to evaluate the role of para-aortic lymph node (PALN) dissection in CRC with isolated PALN metastasis. METHODS:Between January 1993 and Marc...
journal_title：Journal of surgical oncology
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更新日期：2010-01-01 00:00:00
