Abstract：
BACKGROUND:Local recurrence (LR) of sacral chordoma is a difficult problem and the mortality risk associated with LR remains poorly described. The purpose of this study was to evaluate the risk of mortality in patients with LR and determine if patient age is associated with mortality. METHODS:A total of 218 patients (144 male, 69 female; mean age 59 ± 15 years) with sacrococcygeal chordomas were reviewed. Cumulative incidence functions and competing risks for death due to disease and nondisease mortality were employed to analyze mortality trends following LR. RESULTS:The 10-year overall survival (OS) was 55%. Patients with LR had 44% 10-year OS, similar to patients without (59%; P = .38). The 10-year OS between those less than 55 compared with ≥55 years were similar (69% vs 48%; P = .52). The 10-year death due to disease was worse in patients with LR compared with those without (44% vs 84%; P < .001). In patients without LR, patients ≥55 years were 1.6-fold more likely to experience death due to other causes. CONCLUSIONS:Patients with an LR are more likely to die due to disease. Advanced patient age was associated with higher all-cause mortality following resection of sacral chordoma. LR of chordoma was associated with increased disease-specific mortality, regardless of age.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Houdek MT,Hevesi M,Schwab JH,Yaszemski MJ,Griffin AM,Healey JH,Ferguson PC,Hornicek FJ,Boland PJ,Sim FH,Rose PS,Wunder JSdoi
10.1002/jso.25774subject
Has Abstractpub_date
2019-11-22 00:00:00eissn
0022-4790issn
1096-9098pub_type
杂志文章abstract：:Maximum diameter, tumour volume, and inflammatory response of host tissue in 282 surgical specimens with primary carcinoma of the bronchus were measured. Cell type, pT- and pN-stage, maximum diameter and volume of the primaries, and inflammatory response of host tissue were analyzed in respect to survival of the patie...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.2930360203
更新日期：1987-10-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:We assessed the optimal extent of lymph node dissection and the effect of splenectomy in patients with proximal gastric cancer. METHOD:Recurrence and survival rates were compared between 881 patients with proximal gastric cancer who underwent modified radical lymphadenectomy and 3,098 patient...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.21137
更新日期：2008-12-01 00:00:00
abstract：:The journey of gastrinomas had its beginnings in 1955 when Zollinger and Ellison published their seminal paper (Zollinger and Ellison, Ann Surg 1955; 142: 709-723). The evolution of the diagnosis and management of this syndrome has paralleled many important advances in medicine, including the development of various di...
journal_title：Journal of surgical oncology
pub_type： 历史文章,杂志文章,评审
doi：10.1002/jso.21359
更新日期：2009-10-01 00:00:00
abstract：INTRODUCTION:Adult intussusception is rare. Most general and colorectal surgeons are unfamiliar with its etiology and optimal management. PATIENTS AND METHODS:Patients older than 16 years and diagnosed with intestinal intussusception between January 1990 and June 2006 were retrospectively reviewed. Data related to pre...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.21117
更新日期：2008-11-01 00:00:00
abstract：:Malignant bowel obstruction (MBO) is a common problem for patients with advanced malignancy, especially colorectal and ovarian cancers. Symptoms include pain, bloating, nausea and vomiting, and inability to eat. Treatment options consist of a wide range of surgical and nonsurgical interventions (medications, endoscopi...
journal_title：Journal of surgical oncology
pub_type： 杂志文章,评审
doi：10.1002/jso.25451
更新日期：2019-07-01 00:00:00
abstract：PURPOSE:Imatinib mesylate (IM) demonstrates substantial efficacy in most patients with metastatic gastrointestinal stromal tumors (GISTs). However, progression of GIST eventually develops and emerges as a challenge. To assess the role of surgery in the multidisciplinary management of GISTs, we studied the surgical outc...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.21630
更新日期：2010-11-01 00:00:00
abstract：BACKGROUNDS AND OBJECTIVES:The aim of this study was to describe the epidemiology and treatment of skin adnexal carcinoma (SAC) in the Netherlands and to identify prognostic factors for survival in patients with SAC. METHODS:We used population-based nationwide data from the Netherlands Cancer Registry with cases diagn...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.23331
更新日期：2013-06-01 00:00:00
abstract：:This report describes the findings of an extra-adrenal paraganglioma and chondroma of the lung in an elderly man. Tissue analysis of the paraganglioma showed a high level of catecholamines, as well as the presence of somatostatin and small amounts of other peptide hormones. Immunoperoxidase staining demonstrated the d...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.2930350205
更新日期：1987-06-01 00:00:00
abstract：:The majority of patients with pulmonary metastases from primary soft tissue sarcomas have peripheral lesions that can be removed by wedge excision. A subset of these patients, however, present with, or develop, clinically significant endobronchial metastases. These patients require a preoperative evaluation that inclu...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.2930320305
更新日期：1986-07-01 00:00:00
abstract：:From August 1979 to May 1986, various brachytherapy techniques were applied at Memorial Sloan Kettering Cancer Center (MSKCC) in an adjuvant setting with/without surgery and external radiation therapy in the management of advanced malignant melanoma. Thirty-three patients underwent brachytherapy procedures. The patien...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.2930430407
更新日期：1990-04-01 00:00:00
abstract：BACKGROUND:Skip metastasis to mediastinal lymph nodes is a well-known phenomenon in non-small cell lung cancer (NSCLC). Little is reported in the literature about its clinical importance. It is still under discussion whether any prognostic differences exist between resected NSCLC with either skip metastases or continuo...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.10219
更新日期：2003-04-01 00:00:00
abstract：:A case of qualitative platelet dysfunction following cancer chemotherapy is documented. Besides the numerical reduction defect, there appear to be functional changes in the platelets leading to bleeding diathesis. The present case was thoroughly evaluated, and it was observed that there is suppression of the platelet ...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.2930250308
更新日期：1984-03-01 00:00:00
abstract：OBJECTIVES:To investigate predictors of occult nipple-areolar complex (NAC) involvement in patients with carcinoma in situ (CIS) and to validate an online probability calculator (CancerMath; www.lifemath.net/cancer/breastcancer/nipplecalc/index.php). METHODS:Mastectomized patients with CIS (n = 104) were retrospective...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.24768
更新日期：2017-12-01 00:00:00
abstract：:A massive lymphatic leak developed following radical retroperitoneal lymph node dissection for recurrent extragonadal seminoma. Chylous ascites persisted for over 3 months, with an average daily external drainage of 1.5 liters, and was successfully treated with a peritoneovenous shunt. ...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.2930360315
更新日期：1987-11-01 00:00:00
abstract：:A comparative study of alpha-fetoprotein (AFP) and carcinoembryonic antigen (CEA) in serum was made by radioimmunoassay in 66 patients with pancreatobiliary disease with and without obstructive jaundice. biliary concentrations of these proteins were assayed in 12 patients with benign and 7 patients with malignant dise...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.2930190411
更新日期：1982-04-01 00:00:00
abstract：:Whole breast reconstruction using autologous tissue is the gold standard in many regions of the world. Reasons include breast replacement with native skin and fat, ability to shape and mold the tissue into a breast, no foreign materials are necessary, and it lasts forever when successful. There are now many options fo...
journal_title：Journal of surgical oncology
pub_type： 杂志文章,评审
doi：10.1002/jso.24208
更新日期：2016-06-01 00:00:00
abstract：:A totally implantable venous access system is described which greatly improved the ability to gain long-term venous access in selected patients. The external jugular approach has been demonstrated to be a safe and simple technique. The only major problem associated with the implantable venous access system was the dev...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.2930370413
更新日期：1988-04-01 00:00:00
abstract：BACKGROUND:Limb salvage is viable in the majority of patients with malignant bone tumors, but especially in case of extensive tumors and bad soft tissue conditions, it is challenging in upper extremity. OBJECTIVES/METHOD:The clinical and radiological results of 21 patients, who had free vascularized fibular grafts (VF...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.20326
更新日期：2006-08-01 00:00:00
abstract：BACKGROUND:Prone extralevator abdominoperineal excision of the rectum (ELAPE) has been introduced to improve the circumferential resection margins (CRM) compared with traditional APER. OBJECTIVE:We present short-term results achieved with prone ELAPE preceded by neoadjuvant chemoradiotherapy during the last 5 years of...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.24257
更新日期：2016-07-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:We performed a retrospective analysis to assess the influence of different prognostic factors, including the International Prognostic Index (IPI), that can predict the outcome in patients with primary large bowel lymphoma (Stage IE) treated with combined therapy (surgery followed by chemothera...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.10103
更新日期：2002-06-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Tumor thickness is considered the single most important predictor of survival in clinically localized malignant melanoma. A recent study found tumor volume a more sensitive predictor of survival than thickness. Volume measurement, however, is complicated, time consuming, and based on biologica...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/(sici)1096-9098(199810)69:2<83::aid-jso7>3
更新日期：1998-10-01 00:00:00
abstract：:The expression of intercellular adhesion molecule-1 (ICAM-1) was investigated in frozen sections obtained from 40 resected liver specimens of patients with hepatocellular carcinoma using immunoperoxidase techniques and immunoelectron microscopy. ICAM-1 was expressed in 80% of the HCC specimens on the membrane of cance...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.2930530410
更新日期：1993-08-01 00:00:00
abstract：:Fibronectin (FN) was investigated in 75 stroma from lung adenocarcinoma patients. Distribution of FN was classified into three patterns based on immunohistochemical evidence: dense, moderate, and sparse distribution. The incidence of the sparse pattern in both stage I and stage III disease was significantly greater in...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.2930430208
更新日期：1990-02-01 00:00:00
abstract：INTRODUCTION:Breast conservative surgery (BCS) and sentinel lymph node biopsy (SLNB) after neoadjuvant treatment (NAT) is safe and effective for selected patients. This aim of this study is to evaluate the impact of anatomic site of response on outcomes and to assess the real population who may benefit from nonsurgical...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.26236
更新日期：2021-01-01 00:00:00
abstract：PURPOSE:The aims of the study were to estimate the frequency of epiphora and to identify factors associated with epiphora after orbital-sparing maxillectomy via modified Weber-Ferguson incision with lower blepharoplasty (OSOSM-MWFILB). METHODS:We performed a retrospective cohort study enrolling a sample derived from t...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.26408
更新日期：2021-02-01 00:00:00
abstract：:Between 1989 and 1991, 150 patients with ovarian cancer were treated with chemotherapy, including cisplatin, in the Tokai Ovarian Tumor Study Group. Of these patients, 25 underwent cytoreductive surgery with lymphadenectomy, including removal of either pelvic or para-aortic lymph nodes, and 36 underwent both lymphaden...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.2930600403
更新日期：1995-12-01 00:00:00
abstract：:Twenty gastrointestinal lipomata in 18 patients are reviewed: 15 located in the colon, 3 in the distal ileum, one in the duodenum, and one in the stomach. They were found most frequently in European-born, elderly women and presented with variable abdominal symptomatology. Four lipomata were removed during endoscopy, t...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.2930470307
更新日期：1991-07-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:miR-301a is significantly overexpressed in many cancers. However, its expression and biological role in gastric cancer remain poorly understood. We investigated microRNA-301a (miR-301a) expression in gastric cancer and determined its effects on cancer cell behavior and its clinical significanc...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.23374
更新日期：2013-09-01 00:00:00
abstract：:Retroperitoneal sarcoma (RPS) patients can have variable of outcomes after surgery. The chance to recur locally or at distant sites varies according to tumor grade, histologic subtype, and other patient- and tumor-related characteristics. The relative contribution of each prognostic variable on the oncological outcome...
journal_title：Journal of surgical oncology
pub_type： 杂志文章,评审
doi：10.1002/jso.24903
更新日期：2018-01-01 00:00:00
abstract：:The efficacy of killing small cell lung cancer (SCLC) cells at the G1, S, and G2-M phase of the cell-cycle by a new 111In-bleomycin complex (111In-BLMC) was investigated. SCLC cells (N417, H526, H209) were synchronized by double thymidine block and assessed by DNA content with flow cytometry, and the period for the ma...
journal_title：Journal of surgical oncology
pub_type： 杂志文章
doi：10.1002/jso.2930400203
更新日期：1989-02-01 00:00:00
