Abstract:
BACKGROUND:Limb salvage is viable in the majority of patients with malignant bone tumors, but especially in case of extensive tumors and bad soft tissue conditions, it is challenging in upper extremity. OBJECTIVES/METHOD:The clinical and radiological results of 21 patients, who had free vascularized fibular grafts (VFG), for diaphyseal (14), and epipyseal (7) defect reconstruction of the upper extremity, are presented. The indications for VFG were resection after osteosarcoma (9 cases), Ewings sarcoma (9 cases), chondrosarcoma (1 case), rhabdomyosarcoma (1 case), and 1 case of fibrous dysplasia. The 20 malignant tumors were staged as follows: 2a (1), 2b (18), 3 (1). The mean follow-up was 43.6 months (min 6.0-max 131.9). Functional results were described and graded quantitatively according to the MSTS-score. RESULTS:Results were satisfactory with regard to pain, emotional acceptance, manual dexterity, and function. Lifting ability was decreased in two patients. Hypertrophy index was 31% (min 13%-max 71%). Main complications were fracture (5), pseudoarthrosis (4), prolonged wound healing (4), temporary nerve irritation (2), and deep infection (1). Re-operation was required in eight patients (12 operations). CONCLUSION:VFG offers a good possibility for biological reconstruction of large skeletal defects, with an acceptable complication and re-operation rate. When conservative treatment of complications was not successful, further surgery led to recovery in the majority of cases.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Gebert C,Hillmann A,Schwappach A,Hoffmann Ch,Hardes J,Kleinheinz J,Gosheger Gdoi
10.1002/jso.20326subject
Has Abstractpub_date
2006-08-01 00:00:00pages
114-27issue
2eissn
0022-4790issn
1096-9098journal_volume
94pub_type
杂志文章abstract::Surgical procedures for breast cancer were compared in 468 cases with in-situ and 4,967 cases with invasive lesions. The cases were obtained from the Michigan Cancer Foundation Registry, a Surveillance, Epidemiology, and End Results (SEER) participant, and were incident-resident cases diagnosed from 1973-1978. For sin...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930200207
更新日期:1982-06-01 00:00:00
abstract::A totally implantable venous access system is described which greatly improved the ability to gain long-term venous access in selected patients. The external jugular approach has been demonstrated to be a safe and simple technique. The only major problem associated with the implantable venous access system was the dev...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930370413
更新日期:1988-04-01 00:00:00
abstract:BACKGROUND:The aim of this study is to describe the influence of geography, socio-economic development, and demographic shift on the trends in global incidence, mortality, and prevalence of liver cancer (LC). METHODS:Data (2012-2030) relating to LC and demographic shifts based on WHO regions and HDI areas were extract...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24518
更新日期:2017-04-01 00:00:00
abstract::Remote access approaches for thyroid surgery using surgical incisions placed outside the neck, including the axillary, chest and the retro-auricular region have gained interest due to the social stigmatization of young females with a visible neck scar. These novel approaches have been reported to be safe and feasible ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.23955
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Fibrolamellar carcinoma (FLC) presents in young, otherwise-healthy individuals. This study examined recurrence and survival characteristics after surgical resection for FLC by utilizing an international multi-institutional database. METHODS:Consecutive patients undergoing hepatectomy for FLC ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23658
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Laparoscopy-assisted total gastrectomy (LATG) has not gained popularity due to the technical difficulty of esophagojejunostomy (EJ) and the high incidence of EJ-related complications. Herein, we compared two types of EJ for Roux-en-Y reconstruction to determine whether semi-end-to-end (SETE) EJ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24637
更新日期:2017-08-01 00:00:00
abstract::Anastomotic complications are responsible for significant morbidity and mortality following esophagectomy for cancer. Conflicting reports exist regarding the superiority of hand-sewn versus stapled techniques. This systematic review identified eight randomized clinical trials examining this issue. None of the studies ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.21510
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND:Giant cell tumor of bone (GCTB) is an aggressive benign bone tumor with poor prognosis whose neoplastic component is stromal cells (SCs). Tumor stem-like cells (TSCs) have been demonstrated as precursors for tumor genesis and growth. The aim of this study is to identify TSCs in GCTB. METHODS:Stro-1(+) and S...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23151
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The aim of this study was to analyze the stage migration and survival of endometrial cancer by the revised FIGO 2008 staging system compared with the 1988 staging system. METHODS:A total of 355 patients with endometrial cancer, who underwent complete surgical staging, were enrolled. We compar...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23203
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:We performed a retrospective analysis to assess the influence of different prognostic factors, including the International Prognostic Index (IPI), that can predict the outcome in patients with primary large bowel lymphoma (Stage IE) treated with combined therapy (surgery followed by chemothera...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.10103
更新日期:2002-06-01 00:00:00
abstract:BACKGROUND:The aim of this study was to analyze the potential utilization of external jugular vein (EJV) cutdown approach for totally implantable venous access device (TIVAD) placement. METHODS:This is a prospective, non-randomized, observational, uni-institutional study. All patients (n = 451) were first subjected to...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21341
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Some schwannomas in the central nervous system may demonstrate relatively aggressive behavior in pathological findings and clinical course. We evaluate the diagnostic values of telomerase activity and telomere length in the clinicopathological behavior of schwannomas. METHODS:Thirty surgical ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.10139
更新日期:2002-10-01 00:00:00
abstract::A patient with metastasizing glucagonoma producing multiple molecular forms of glucagon is reported. The patient responded to symptomatic treatment with a somatostatin analogue (SMS 201-995). Glucagonoma tumour cells were studied in two tissue culture systems: intraocular transplants of immunosuppressed rats and long-...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930440313
更新日期:1990-07-01 00:00:00
abstract:INTRODUCTION:Low-heat treated autograft may have an advantage over allograft in that they provide a size-matched and biologically compatible graft. MATERIALS AND METHODS:We compared the graft survival and complications between the low-heat treated autografts (n = 13) and allografts (17) for intercalary reconstruction ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23727
更新日期:2014-12-01 00:00:00
abstract::A new simplified system for updating a cancer registry has been developed in the Biostatistics Department of Roswell Park Memorial Institute. It was designed to serve the needs of maintaining a registry for a cooperative cancer research group. The Data-Update Procedure at a Remote Terminal (DUPART) system has general ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930070508
更新日期:1975-01-01 00:00:00
abstract::DNA ploidy of tumor cells and the degree of infiltration of dendritic cells were determined in 93 gastric cancer tissue specimens, and the mechanisms of tumor-host interaction on the prognosis were investigated. DNA ploidy patterns were grouped into low and high ploidy, and the degree of infiltration of dendritic cell...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930520402
更新日期:1993-04-01 00:00:00
abstract::In this review, we aim to assess the current state of science in relation to the integration of patient-generated health data (PGHD) and patient-reported outcomes (PROs) into routine clinical care with a focus on surgical oncology populations. We will also describe the critical role of artificial intelligence and mach...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.26232
更新日期:2021-01-01 00:00:00
abstract::A patient with a feminizing malignant Leydig cell tumor is presented. Hormonal assays revealed increased production of prolactin, estradiol, and total estrogens. Eleven years after the onset of his disease he remains clinically well. ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930270203
更新日期:1984-10-01 00:00:00
abstract::Three patients with unresectable malignant retroperitoneal tumors that invaded and perforated the distal duodenum presented with sepsis unresponsive to antibiotics. A technique of proximal side-to-side duodenojejunostomy with stapled occlusion of the distal duodenum resulted in successful diversion and immediate resol...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930260410
更新日期:1984-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The volume-outcome relationship is well recognized. We sought to investigate this relationship in retroperitoneal sarcoma (RPS) surgery. METHODS:Non-metastatic RPS cases from 2004 to 2014 in the National Cancer Database were analyzed. Hospitals in the top 10th percentile for volume were defin...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24710
更新日期:2017-11-01 00:00:00
abstract:INTRODUCTION:National Comprehensive Cancer Network guidelines recommend that sentinel lymph node biopsy (SLNB) be discussed with patients with thin melanoma at higher risk for lymph node metastasis (T1b or T1a with positive deep margins, lymphovascular invasion, or high mitotic index). We examined the association betwe...
journal_title:Journal of surgical oncology
pub_type: 临床试验,杂志文章
doi:10.1002/jso.26225
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:Malignant hip lesions can be managed operatively by intramedullary (IM) nail fixation and hemiarthroplasty. METHODS:A retrospective review was performed on 86 patients who underwent hemiarthroplasty (n = 22) or IM nail fixation (n = 64) for prophylactic treatment of impending pathologic fracture due to mali...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24792
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:HER family is an attractive target for the treatment of esophageal cancer. The clinical relevance of HER-4 has not been yet characterized. METHODS:The expression of HER-4 was immunohistochemically examined in 61 surgically resected esophageal squamous cell carcinomas (ESCC), and the prognostic significance ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20892
更新日期:2008-01-01 00:00:00
abstract::The aim of this study was to establish the role of estrogen receptor (ER) and progesterone receptor (PgR) as prognostic indicators for early recurrence and survival. In all, among breast cancer patients, 166 patients who had undergone radical or extended radical mastectomy were studied. These patients were treated wit...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930390207
更新日期:1988-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Several tumor-related antigen peptides that are recognized by autologous cytolytic T cells (CTL) have been reported. However, most human solid tumors, including gastric carcinoma, are only weakly immunogenic. In this study, we focused on interleukin (IL)-12 and interferon-gamma (IFN-gamma) as ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9098(199801)67:1<11::aid-jso3>3
更新日期:1998-01-01 00:00:00
abstract::A 38-year-old woman with early stage invasive breast cancer was treated with wide excision of the tumor, axillary lymph node dissection, and breast irradiation. Three years later, she gave birth to a normal baby. She attempted breast feeding and had full lactation from the untreated breast. The irradiated breast under...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930460214
更新日期:1991-02-01 00:00:00
abstract::Mice with intravesical urothelial tumors (MBT-2) were challenged with E coli inoculated intravesically. Adherence of bacteria measured at 15 min or persistent infection at 24 h was significantly greater in the tumor-bearing bladders than in normal non-tumor-bearing mice. The tumor-bearing portion of the bladder contai...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930230405
更新日期:1983-08-01 00:00:00
abstract:BACKGROUND:Randomized controlled trials have demonstrated comparable survival outcomes for short-course (SCRT) and long-course neoadjuvant radiotherapy (LCRT) in patients with rectal cancer. METHODS:Using the National Cancer Data Base (2004-2015), a propensity score was used to match 188 patients with rectal cancer re...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25355
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Among several long-term effects, people treated for cancer may experience an altered appearance. Our study aims to identify how visible body changes following surgical treatment affect the life and identity of primary bone sarcoma survivors 3-10 years after diagnosis. A qualitative, phenomenol...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24138
更新日期:2016-02-01 00:00:00
abstract::In order to determine whether current programs for the management of metastatic breast cancer have led to improved patient survival, we determined the median survival times for five-year intervals of 849 patients admitted to the City of Hope National Medical Center with metastatic breast cancer from 1955 to 1980. Surv...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930480304
更新日期:1991-11-01 00:00:00