Abstract:
INTRODUCTION:Low-heat treated autograft may have an advantage over allograft in that they provide a size-matched and biologically compatible graft. MATERIALS AND METHODS:We compared the graft survival and complications between the low-heat treated autografts (n = 13) and allografts (17) for intercalary reconstruction of malignant bone tumors. Average age was 25 years with follow-up of 6.6 years (1.8-12.5). For low-heat treatment, the resected bone was treated in saline at 65°C for 30 min. Nineteen grafts were fixed with plates and 13 with intramedullary nails. RESULTS:Until last follow-up, five low-heat treated autografts (38%) and one allograft (6%) had been removed, with allografts showing a trend toward better survival on Kaplan-Meier analysis (P = 0.293). Complications were more common in low-heat treated autograft group [10/13 (77%) vs. 8/17 (47%), P = 0.098)]. Low-heat-treated autograft resulted in significantly higher rate of nonunion [11/26 (42%) vs. 5/34 (15%), P = 0.017] and required higher number of operations to treat nonunion (P = 0.004). Rates of graft fracture [3/13 (23%) vs. 2/17 (12%), P = 0.713)] or infection [2/13 (15%) vs. 1/17 (6%), P = 0.565)] were similar. CONCLUSION:Our data suggest that intercalary allograft has better survival and fewer complications than the low-heat treated autograft.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Han I,Kim JH,Cho HS,Kim HSdoi
10.1002/jso.23727subject
Has Abstractpub_date
2014-12-01 00:00:00pages
823-7issue
7eissn
0022-4790issn
1096-9098journal_volume
110pub_type
杂志文章abstract:BACKGROUND:Gallbladder adenocarcinoma is often incidentally identified following cholecystectomy. We hypothesized that intraoperative bile spillage would be a negative prognostic factor. METHODS:A retrospective review of patients treated at a cancer center with histologically confirmed gallbladder adenocarcinoma, 2009...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25617
更新日期:2019-09-01 00:00:00
abstract::The results of treatment with intracavitary bleomycin are reported in twenty patients with a malignant pleural effusion and five patients with malignant ascites. The control rate was 17/20 (85%) patients with malignant pleural effusions and 3/5 (60%) patients with malignant ascites. Toxicities were minimal with fever ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930160312
更新日期:1981-01-01 00:00:00
abstract::Palliative care (PC) seeks to improve the quality of life for patients facing serious illness. Several oncology organizations have guidelines about PC, reflecting the need to integrate PC into standard oncology care. Many surgical patients do not receive PC despite the need for these services and established surgical ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.25449
更新日期:2019-07-01 00:00:00
abstract::The aim of this study was to establish the role of estrogen receptor (ER) and progesterone receptor (PgR) as prognostic indicators for early recurrence and survival. In all, among breast cancer patients, 166 patients who had undergone radical or extended radical mastectomy were studied. These patients were treated wit...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930390207
更新日期:1988-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:We evaluated the clinicopathological associations and prognostic implications of promyelocytic leukemia gene (PML) expressions in patients with esophageal squamous cell carcinomas (ESCC) receiving primary surgery. METHODS:Expression patterns of PML and tumor protein 53 (TP53) of 132 cases of ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21855
更新日期:2011-06-01 00:00:00
abstract::Responsiveness of experimental chemotherapy on human cancer xenografts in nude mice was directly compared with clinical response to the same chemotherapy in their donor patients. These xenografts were 1 line of rectal cancer (H-26), two lines of gastric cancer (H-08 and H-22), and 1 line of breast cancer (H-62). Exper...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930150304
更新日期:1980-01-01 00:00:00
abstract:BACKGROUND:Studies for patients with pelvic chondrosarcomas are limited. This study determines the outcome of patients with pelvic chondrosarcomas, and whether there is any association with tumors' grade, type, stage, margins and pelvic location. MATERIALS AND METHODS:We retrospectively studied 215 patients with pelvi...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23351
更新日期:2013-07-01 00:00:00
abstract::In this review, we aim to assess the current state of science in relation to the integration of patient-generated health data (PGHD) and patient-reported outcomes (PROs) into routine clinical care with a focus on surgical oncology populations. We will also describe the critical role of artificial intelligence and mach...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.26232
更新日期:2021-01-01 00:00:00
abstract::Inflammatory carcinoma of the breast is rare and lethal. Since the early 1940s, operation except for biopsy has been contraindicated in patients with inflammatory breast cancer. Results with radiotherapy alone and with radiotherapy and chemotherapy are reviewed. Results of treating patients with initial chemotherapy a...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930230408
更新日期:1983-08-01 00:00:00
abstract::RLV-A serum activity was measured by the agar colony assay to determine the effect of this erythroid dyscrasia on the granulopoietic humoral regulator, colony stimulating factor (CSF). In general, the sera of early, midstage and terminal animals not given endotoxin had high cluster forming properties compared to norma...
journal_title:Journal of surgical oncology
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doi:10.1002/jso.2930130312
更新日期:1980-01-01 00:00:00
abstract:INTRODUCTION:Patients with Stage IV melanoma have limited therapeutic options with few long-term survivors. Our goal was to study the impact of metastasectomy on survival in these patients. METHODS:Patients with Stage IV melanoma were identified from the Surveillance, Epidemiology, and End Results (SEER) database (198...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21903
更新日期:2011-08-01 00:00:00
abstract:INTRODUCTION:We report our institutional experience with extrahepatic metastasectomy (EM) in a cohort of hepatocellular carcinoma (HCC) patients with focus on predictors of survival. METHODS:All patients diagnosed with metastatic HCC from 2001 to 2014 were retrospectively reviewed to identify those who underwent EM wi...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24340
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:The aim of the present study was to evaluate the histopathological characteristics of gastric submucosal tumors (SMTs) according to their location. METHODS:A retrospective analysis of a prospective database of 151 consecutive patients who underwent surgery for gastric SMTs between 2001 and 2009 was performe...
journal_title:Journal of surgical oncology
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doi:10.1002/jso.21771
更新日期:2011-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Small lung adenocarcinomas are detected more frequently than in the past. However, the clinicopathologic characteristics and prognostic significance of EGFR/p53 mutations in these tumors remains unclear. METHODS:We evaluated the correlation of EGFR/p53 mutations with clinicopathologic charact...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23628
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Re-excision surgery is undertaken to obtain clear margins after breast-conserving surgery (BCS) for localized breast cancer. This study examines patient and tumor characteristics related to re-excision surgery in the universal-access Military Health System (MHS). METHODS:Retrospective analysi...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25788
更新日期:2019-11-29 00:00:00
abstract::Metastasis to the breast is uncommon, with an incidence of 0.5-3%. Alveolar soft part sarcoma is rare, accounting for < 1% of malignant soft tissue tumors, which are themselves unusual. Excluding contralateral breast and hematologic malignant disease, the primary lesion in most cases of metastasis to the breast is mel...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/(SICI)1096-9098(199602)61:2<159::AID-JSO13
更新日期:1996-02-01 00:00:00
abstract::Microsurgical techniques have revolutionized pharyngolaryngeal reconstruction. Free flap reconstruction with the free jejunal flap enables one stage reconstruction with minimal morbidity and mortality. This review will examine indications, operative technique, postoperative management, and expected outcomes for the hy...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.20483
更新日期:2006-11-01 00:00:00
abstract::Esophageal small cell carcinoma is a highly aggressive disease, and no effective treatment has yet been reported. We present here two cases of esophageal small cell carcinoma preoperatively treated with a combination of hyperthermia, irradiation, and an intravenous infusion of cis-diammine-dichloroplatinum (CDDP). The...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930590115
更新日期:1995-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:To evaluate the impact of plasminogen activator (PA) system genes, including urokinase plasminogen activator (uPA), uPA receptor (uPAR), and plasminogen activator inhibitor-1 (PAI-1) gene polymorphisms in patients with the cervical neoplasia. METHODS:In total, 336 blood samples were collected...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23072
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:Randomized controlled trials have demonstrated comparable survival outcomes for short-course (SCRT) and long-course neoadjuvant radiotherapy (LCRT) in patients with rectal cancer. METHODS:Using the National Cancer Data Base (2004-2015), a propensity score was used to match 188 patients with rectal cancer re...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25355
更新日期:2019-03-01 00:00:00
abstract::To define more precisely the prognostic index for patients with primary carcinoma of the gallbladder in Taiwan, we retrospectively reviewed the data of 74 patients with gallbladder carcinoma treated over a period of 15 years, from 1979 to 1993. Of these patients, 75% had Nevin stage V gallbladder cancer. The most comm...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/(SICI)1096-9098(199601)61:1<49::AID-JSO11>
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:To evaluate the predicting value of the epidermal growth factor receptor (EGFR) for survival in patients with head and neck cancer (HNC). METHODS:Data were collected from studies comparing overall survival (OS) or progression-free survival (PFS) in patients with higher or lower EGFR levels. S...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,meta分析
doi:10.1002/jso.23406
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:The role of postmastectomy radiation therapy (PMRT) after neoadjuvant chemotherapy (NAC) and mastectomy is unclear, especially in patients that have post-treatment tumor negative axillary nodes (ypN0). METHODS:The National Cancer Data Base was used to identify women that had PMRT after NAC and mastectomy fo...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24551
更新日期:2017-05-01 00:00:00
abstract::Patients undergoing neoadjuvant therapy for esophageal cancer are at a high risk for malnutrition due to the effects of chemoradiation, dysphagia, and malignancy induced cachexia. Preparation for esophagectomy requires careful assessment of nutritional risk and adequate supplementation as indicated. Supplementation vi...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.21289
更新日期:2009-07-01 00:00:00
abstract::To evaluate the benefit of R2 gastrectomy for gastric cancer in Japanese patients over 80 years of age, data on 93 patients who underwent gastrectomy between 1967 and 1989 were collected retrospectively from charts filed in the Kyushu University Hospital and two affiliated national hospitals. Of 93 patients, 62 had a ...
journal_title:Journal of surgical oncology
pub_type: 临床试验,杂志文章
doi:10.1002/jso.2930480213
更新日期:1991-10-01 00:00:00
abstract::Locally recurrent cancer of the rectum has been under-recognized as a complication, although it affects up to 40% of patients treated with surgery alone. Even in the best centers, rates average 25%. While radiotherapy may reduce recurrence, it is now apparent that total mesorectal excision is the most effective modali...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/(sici)1096-9098(200001)73:1<47::aid-jso12>
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVES:To identify the prognostic implications of human papillomavirus (HPV)-related cell cycle marker profiles in patients who have received a transoral lateral oropharyngectomy (TLO) as a primary treatment for tonsillar squamous cell carcinoma (TSCC). PATIENTS AND METHODS:Immunohistochemical profiles of HPV-rela...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23672
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The study of pathology and prognosis for patients with ovarian tumors of low malignant potential (LMP) has been well documented. The treatment, particularly the secondary surgery, for recurrent disease is less documented. This study was conducted to investigate the role of secondary surgical c...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20280
更新日期:2005-07-01 00:00:00
abstract:OBJECTIVES:To investigate predictors of occult nipple-areolar complex (NAC) involvement in patients with carcinoma in situ (CIS) and to validate an online probability calculator (CancerMath; www.lifemath.net/cancer/breastcancer/nipplecalc/index.php). METHODS:Mastectomized patients with CIS (n = 104) were retrospective...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24768
更新日期:2017-12-01 00:00:00
abstract::Cell surface sialic acid levels were compared for monocytes and macrophages obtained from normal volunteers and breast cancer patients. Equal quantities of sialic acid were found on the monocytes obtained from normal volunteers and breast cancer patients. Approximately 60% more cell surface sialic acid was found on th...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930220203
更新日期:1983-02-01 00:00:00