Abstract:
BACKGROUND:Leiomyosarcoma of the inferior vena cava (IVC) is a rare tumor which presents a unique surgical challenge. We present a series of six cases of leiomyosarcoma resection performed with IVC reconstruction. METHODS:Retrospective chart review was performed for patients undergoing initial operative resection of primary leiomyosarcoma with IVC reconstruction, at a tertiary care center. RESULTS:Between 2005-2013, six patients underwent resection with reconstruction. Half were female, and the mean age at presentation was 57 ± 15.4 years. Three patients required en bloc resection with adjacent organs. Three patients were resected on venovenous bypass, and one on cardiopulmonary bypass. Three underwent IVC patch repair (bovine pericardium, n = 2; saphenous vein, n = 1), and three had IVC reconstruction with graft (Dacron, n = 1; PTFE, n = 1; aortic homograft, n = 1). All achieved grossly negative margins. Median disease-free survival was 34 months (IQR 7-52 months), and median disease-specific survival was 51 months (IQR 20-108). Five year disease-free and disease-specific survival rates were 30% and 66.7%, respectively. CONCLUSIONS:Leiomyosarcomas of the IVC present a technical challenge to the surgeon. Careful preoperative workup and a collaborative team consisting of experienced cardiac and vascular surgeons and surgical oncologists can allow for a safe and successful operation despite extensive tumor involvement.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Wachtel H,Jackson BM,Bartlett EK,Karakousis GC,Roses RE,Bavaria JE,Fraker DLdoi
10.1002/jso.23798subject
Has Abstractpub_date
2015-03-01 00:00:00pages
328-33issue
3eissn
0022-4790issn
1096-9098journal_volume
111pub_type
杂志文章,评审abstract::Carcinoma of the lung should be considered in the search for an unknown primary lesion when there is evidence of cervical lymph node involvement. Of 1,686 patients with a final diagnosis of bronchogenic carcinoma seen during a 10-year period at the University of Louisville Hospitals, 26 presented one or more clinicall...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930090513
更新日期:1977-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:In this study, we identified matrix metalloproteinase (MMP)-2 and 9 expression in exophytic papilloma (EP), inverted papilloma (IP) with dysplasia, IP with carcinoma, and invasive squamous cell carcinoma (SCC). We also compared the presence of MMP-2 and 9 with human papilloma virus (HPV) infec...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20386
更新日期:2006-01-01 00:00:00
abstract::Infertility because of testicular damage is a distressing problem for survivors of cancer chemotherapy. We have previously described a cytoprotective effect of temporary testicular circulatory isolation (TCI) during doxorubicin administration in the rat. In this report we define the relationship between duration of TC...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930390410
更新日期:1988-12-01 00:00:00
abstract:OBJECTIVES:To investigate the immunoreactivity of TTF-1 and PAX8 in neuroendocrine carcinoma of thymic (TNEC) and pulmonary origins (PNEC), and whether their immunophenotyping could be used to distinguish between NEC of the two sites, as well as prognosis of patients with TNEC. METHODS:Twenty-two cases of TNEC and 20 ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24393
更新日期:2016-11-01 00:00:00
abstract::Twenty-nine patients with advanced refractory breast cancer were treated with cisplatin 20 mg/m2/d and VP-16 100 mg/d for 5 days every 3-4 weeks. Ten patients received mitomycin C 10 mg/m2 every 6 weeks additionally. Partial response was obtained in 10 of 26 evaluable patients (38%). The response rates for the group t...
journal_title:Journal of surgical oncology
pub_type: 临床试验,杂志文章
doi:10.1002/jso.2930500411
更新日期:1992-08-01 00:00:00
abstract::Pancreatic cancer is a highly lethal malignancy that often presents at an advanced stage. Surgical resection can prolong survival and offers the only potential for cure. However, pancreatectomy is associated with significant morbidity and mortality. This article reviews perioperative outcomes, post-resection long-term...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.23744
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:To compare 3-year clinical outcomes of radiofrequency ablation (RFA) targeting 5- or 10-mm margins for small hepatocellular carcinomas (HCCs) in cirrhotic patients. METHODS:In total, 96 cirrhotic patients with a small solitary HCC (diameter ≤3 cm) were included in this prospective trial (ChiC...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,随机对照试验
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更新日期:2017-06-01 00:00:00
abstract::The ability to redefine risk factors and to predict prognosis in patients with malignant melanoma at the time they manifest nodal metastasis can be a benefit to the patient emotionally and to the physician therapeutically. A retrospective review of 1,273 patients with stage II malignant melanoma was performed at our i...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930390302
更新日期:1988-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:This study assessed the outcomes of Yttrium-90 (90 Y) radiation segmentectomy for hepatic metastases unamenable to resection or ablation. MATERIALS AND METHODS:Over 6 years, 36 patients with 53 tumors underwent segmental radioembolization. Patients were not candidates for surgical resection o...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,多中心研究
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更新日期:2021-01-01 00:00:00
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journal_title:Journal of surgical oncology
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更新日期:2019-09-01 00:00:00
abstract::The classical concepts pertaining to the natural history of mammary carcinoma and its treatment must be reviewed if survival rate is to be improved. By the time diagnosis is established, a fair amount of cases of carcinoma of the breast present distant, clinically undetectable micrometastases, which will not be affect...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930140211
更新日期:1980-01-01 00:00:00
abstract:BACKGROUND:Amongst various options of vascularized lymph node transfers, the submental flap has the lowest risk for iatrogenic lymphedema. The aim of this study was to gain insight into distribution, number, and size of lymph nodes along the mandible using computed tomography angiography (CTA). METHODS:A total of 52 C...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
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更新日期:2020-07-15 00:00:00
abstract:BACKGROUND AND OBJECTIVES:In highly selected patients with peritoneal carcinomatosis, cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) can be an aggressive but worthwhile treatment regimen. Resection of the rectosigmoid is frequently performed with CRS. The aim of the study wa...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
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更新日期:2018-09-01 00:00:00
abstract::Munchausen's syndrome is a chronic factitious disorder characterized by frequent hospitalizations, self-inflicted injuries, and dramatic medical histories. People with this condition assume the role of a sick patient and submit to unnecessary invasive, painful, and even dangerous medical procedures. In review of the l...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.2930560219
更新日期:1994-06-01 00:00:00
abstract:BACKGROUND:Long-term results of the ESPAC-3 trial suggest that while completing adjuvant therapy (AT) is necessary after resection of pancreatic ductal adenocarcinoma (PDAC), early initiation (within 8 weeks) may not be associated with improved overall survival (OS). The primary aim of this study was to evaluate the OS...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24314
更新日期:2016-09-01 00:00:00
abstract::The complications of percutaneous intraarterial infusion chemotherapy of the head-and-neck-cancer patient has dampened enthusiasm for this approach. A totally implantable infusion pump system circumvents many of these complications and will in the long term enhance the opportunity to expand upon the advantages of infu...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930210213
更新日期:1982-10-01 00:00:00
abstract::Patients with advanced glottic cancer, in whom there is extensive subglottic disease and/or low cervical lymph node metastasis, have a high incidence of recurrence in and about the tracheal stoma. Stoma recurrences can be prevented by immediate postoperative megavoltage radiotherapy when the stoma is included in the i...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930070303
更新日期:1975-01-01 00:00:00
abstract::Metastatic colorectal cancer (mCRC) continues to show poor outcomes, with many patients exhausting effective standard-of-care therapy. To explore the current landscape of clinical trials for mCRC, we reviewed over 600 clinical trials that are currently ongoing for mCRC patients. Immunotherapeutic agents form approxima...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.25441
更新日期:2019-04-01 00:00:00
abstract::A 46-year-old man with a second local recurrence of a myxoid liposarcoma in the fossa poplitea, after surgery and high-dose external beam radiotherapy, was successfully treated by a limb-sparing procedure combining marginal excision, intraoperative radiotherapy and reconstructive surgery. After a 48-month follow-up, t...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930530116
更新日期:1993-05-01 00:00:00
abstract::Matrix metalloproteinases (MMPs) are a group of at least 26 enzymes that facilitate cellular invasion via the degradation of the extracellular matrix. Specifically, the ability to degrade collagen types III and I is important in tumor invasion and metastasis. Over expression of the MMP-1 gene has been shown to correla...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20100
更新日期:2004-09-01 00:00:00
abstract:BACKGROUND:CD109, a TGF-β co-receptor, is reported to be preferentially expressed during the early stages of tumorigenesis in several carcinoma types. Myxofibrosarcoma is one of the most common soft-tissue sarcomas found in elderly patients. This study aimed to elucidate the impact of CD109 expression in myxofibrosarco...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23934
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Tumors of the splenic flexure (TSF) can be associated with metastatic lymph nodes (LN) along the left colic pedicle, but also along the superior mesenteric vessels. We aimed to detail the anatomical distribution of metastatic LNs in patients undergoing elective subtotal colectomy for TSF. MET...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
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更新日期:2018-11-01 00:00:00
abstract:OBJECTIVE:To propose a distinct anatomical classification for the superior thyroid pole that may serve as a surgical landmark and could help reduce complications in thyroid surgery. MATERIALS AND METHODS:A comprehensive anatomical study based on existing literature and surgical observations. RESULTS:The proposed supe...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23950
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:Minimally invasive and functional therapy represents an inevitable trend in breast surgery. Improved visualization during mastoscopic axillary lymph node dissection (MALND) realizes a clear exposure of axillary anatomy, but it differs from a general laparoscopic operation. There are some challenges in techni...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21080
更新日期:2008-08-01 00:00:00
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journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21440
更新日期:2010-02-01 00:00:00
abstract::Five patients with breast cancer and malignant melanoma are reported. Two patients had a third primary malignancy. In 4 out of 5 patients the breast tumor was the initial tumor discovered, and in 4 out of 5 the second tumor evolved metachronously. No specific carcinogenic factor could be established. The low malignanc...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930070305
更新日期:1975-01-01 00:00:00
abstract::We studied 148 colorectal adenocarcinomas to clarify any correlation between HLA-DR antigen expression on tumor cells and histopathological features. Paraffin sections of formalin-fixed tissues were stained with HLA-DR antigen using the indirect immunoperoxidase technique. All the tumor tissues were divided into two g...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930590407
更新日期:1995-08-01 00:00:00
abstract::An unusual case of Merkel cell carcinoma of the lower lip with metastasis to the submental nodes is presented. Clinical similarities and the histopathologic and prognostic differences between this tumor and basal or squamous cell carcinomas of the head and neck area are discussed and the current thoughts for treatment...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930370212
更新日期:1988-02-01 00:00:00
abstract::The primary modality of treatment for a localized soft tissue sarcoma is surgical resection. Adjuvant or neoadjuvant radiation helps reduce the rate of local recurrence. The rate of limb preserving resection is 94% in our series. Local recurrence can be re-excised in 95% of the patients, with limb preservation in 90%....
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
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更新日期:2010-06-15 00:00:00
abstract::We report here on two female patients who had permanent pacemakers implanted in their chests and who developed carcinoma of the breast subsequently. An association is suspected between the breast cancer and the pacemaker, which is implanted in an area which borders with the mammary gland or is even right within it. Th...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930110103
更新日期:1979-01-01 00:00:00