Abstract:
PURPOSE:To explore the time and pattern of recurrence of proximal gastric cancer and estimate the risk factors and prognostic factors for it. Considering these risk factors, postoperative adjuvant therapies and follow-up program can be individualized. METHODS:The data of 135 recurrence proximal gastric cancer patients were extracted and analyzed. RESULTS:In 135 recurrence patients, the median time to recurrence was 14.0 months, 116 (85.9%) patients had recurrences within 2 years. Loco-regional recurrence was the most prevalent pattern. Hematogenous metastasis was next prevalent pattern in which the liver was the most common organ. Peritoneal recurrence occurred in 32 patients. Five patients recurred in distant lymph nodes. The deeper invasion was associated with higher incidence of hematogenous metastases and peritoneal recurrence. The histological type, depth of invasion, and lymph node metastasis were independent risk factors for overall recurrence. While, negative lymph nodes counts were another independent risk factors for early recurrence. Patients with systemic recurrence and early recurrence patients had poorer prognosis. CONCLUSION:Total gastrectomy and adequate lymph nodes dissection were rational choice of proximal gastric cancer with deeper invasion. Pathologic predictors of invasion, histological type, lymph nodes metastasis and negative lymph node counts could guide individualized, risk-oriented adjuvant treatment, and follow-up plan.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Li F,Zhang R,Liang H,Liu H,Quan Jdoi
10.1002/jso.23252subject
Has Abstractpub_date
2013-02-01 00:00:00pages
130-5issue
2eissn
0022-4790issn
1096-9098journal_volume
107pub_type
杂志文章abstract:BACKGROUND AND OBJECTIVES:Data on outcomes after liver-directed therapy for intrahepatic cholangiocarcinoma (ICC) are limited due to the rarity of the disease. We sought to define overall utilization and temporal trends of liver-directed therapy for ICC. METHODS:We identified 5,388 patients with ICC using the Surveill...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23605
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Uncertainty exists about the value of cancer therapy in patients aged 90 years and older. Because of the relative paucity of these patients, as well as the possibility of selection bias in any one institution, the use of a large, total population-based cancer registry was employed. METHODS:Th...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.10160
更新日期:2002-11-01 00:00:00
abstract:BACKGROUND:The role of surgical resection in the treatment of patients with metastatic/recurrent gastrointestinal stromal tumors (GIST) is unclear. The aim of this study was to identify preoperative factors associated with oncologic outcomes for recurrent/metastatic GIST after tyrosine kinase inhibitor (TKI) therapy. ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24988
更新日期:2018-04-01 00:00:00
abstract::Three patients treated with bilateral subcutaneous mastectomies and implants for fibrocystic disease or carcinoma in situ subsequently developed invasive breast carcinoma. These cases emphasize that subcutaneous mastectomy does not prevent the development of breast cancer. If the circumstances in an individual patient...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930260313
更新日期:1984-07-01 00:00:00
abstract::The results of treatment with intracavitary bleomycin are reported in twenty patients with a malignant pleural effusion and five patients with malignant ascites. The control rate was 17/20 (85%) patients with malignant pleural effusions and 3/5 (60%) patients with malignant ascites. Toxicities were minimal with fever ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930160312
更新日期:1981-01-01 00:00:00
abstract::Lymph node status is not part of the staging system for cervical cancer, but provides important information for prognosis and treatment. This article reviews the incidence and patterns of lymph node metastasis, and the issues surrounding surgical assessment of lymph nodes. The preoperative assessment of lymph nodes by...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.21199
更新日期:2009-03-15 00:00:00
abstract:BACKGROUND:While sub-2 cm pancreatic neuroendocrine tumors (NETs) are often observed, small bowel-NETs undergo resection and lymphadenectomy regardless of size. Aim was to define the natural history of duodenal (D-NETs), determine the role of resection, and define the factors associated with overall survival (OS) after...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25731
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:When performed at select centers, minimally invasive gastrectomy (MIG) for gastric adenocarcinoma is associated with reduced perioperative morbidity, and similar oncologic outcomes as compared to open gastrectomy (OG). Utilization of, and outcomes associated with, MIG in the United States have...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24052
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Vascularized lymph node transfer (LNT) is gaining popularity in the treatment of lymphedema. However, it is unclear whether the vascularization of transferred lymph nodes (LNs) contributes to functional improvement. High endothelial venules (HEVs) are specialized vessels that allow lymphocytes...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25365
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:We evaluated the efficacy and feasibility of hyperthermic intraperitoneal chemotherapy (HIPEC) using paclitaxel as consolidation therapy in patients with epithelial ovarian cancer. METHODS:Between November 1999 and January 2004, 18 patients with a negative second-look and 1 patient with positive peritoneal ...
journal_title:Journal of surgical oncology
pub_type: 临床试验,杂志文章
doi:10.1002/jso.21448
更新日期:2010-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:To compare 3-year clinical outcomes of radiofrequency ablation (RFA) targeting 5- or 10-mm margins for small hepatocellular carcinomas (HCCs) in cirrhotic patients. METHODS:In total, 96 cirrhotic patients with a small solitary HCC (diameter ≤3 cm) were included in this prospective trial (ChiC...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,随机对照试验
doi:10.1002/jso.24607
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:Treatment decisions for gastrointestinal stromal tumors (GIST) are frequently guided by tumor characteristics. An accurate prediction of recurrence is important to determine the benefit from targeted therapy. Our goal was to compare the concordance of three validated risk stratification schemes with observed...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23839
更新日期:2015-03-15 00:00:00
abstract::During the past 53 years, 105 patients with Wilms' Tumor have been treated at the Children's Hospital of Buffalo. Prospective and retrospective staging of these cases has allowed comparison with other reported series. All-stage survival improved from 37% with operation alone to 46% with operation and planned radiother...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930300410
更新日期:1985-12-01 00:00:00
abstract::This study details the case reports of two children who developed slipped capital femoral epiphyses (SCFE) after receiving external irradiation. The clinical and diagnostic features of postradiation SCFE are reviewed and discussed. Guidelines for the management of children who receive pelvic irradiation are presented....
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930360110
更新日期:1987-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:To determine the prognostic significance of the colposcopic tumor size in the management of cervical cancer. METHODS:Clinicopathological analysis was performed in 751 consecutive patients with stage IB squamous cervical cancer who were surgically treated in a single institute. The colposcopic...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/1096-9098(200102)76:2<133::aid-jso1024>3.0
更新日期:2001-02-01 00:00:00
abstract::A unique association between meningioma and breast cancer has recently been observed. A review of the literature reveals 33 such cases. Certain similarities exist between these two tumors. They each occur more frequently in women in the fifth and sixth decade, and pregnancy accelerates the symptoms of both entities. F...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930310309
更新日期:1986-03-01 00:00:00
abstract::A consecutive series of 100 patients affected by gastrointestinal malignancies entered a prospective controlled study of liver metastases performed by ultrasound echography, CEA, hepatic enzymes (only alkaline phosphatase (AP) was found to be somehow significant). Laparotomic inspection and palpation were taken as obj...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930280302
更新日期:1985-03-01 00:00:00
abstract:BACKGROUND:Detection of tumor cells in lymph nodes (LNs) removed during the treatment of pulmonary tumor by radical surgery is limited by the possibilities of standard histopathological methods. The goal of this study was to obtain more accurate pTNM status by a more sensitive detection of micrometastases in LNs. METH...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24826
更新日期:2018-02-01 00:00:00
abstract::We retrospectively studied the relationship between nutritional status as indicated by the presence or absence of the cutaneous delayed hypersensitivity response and treatment-related morbidity, disease recurrence, and survival at 2 years in 67 consecutive patients with head and neck carcinoma. Serial nutritional asse...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930550110
更新日期:1994-01-01 00:00:00
abstract::Locally recurrent cancer of the rectum has been under-recognized as a complication, although it affects up to 40% of patients treated with surgery alone. Even in the best centers, rates average 25%. While radiotherapy may reduce recurrence, it is now apparent that total mesorectal excision is the most effective modali...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/(sici)1096-9098(200001)73:1<47::aid-jso12>
更新日期:2000-01-01 00:00:00
abstract:UNLABELLED:BACKGROUND AND OBJECTS: Matrix degradation, which is a critical event in the process of tumor invasion and metastasis, is considered to be caused by the action of proteolytic enzymes. METHODS:We examined the gelatinolytic activity of matrix metalloproteinase (MMP)-9, and the activity of active and inactive ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.1030
更新日期:2001-03-01 00:00:00
abstract::We studied the influence of surgical trauma to the iliac bone on the implantation of I.V. injected tumor cells, which formed tumor in the surgical wounds of 27/84 mice (32%). None of these mice or nonsurgical mice developed tumor in the opposite or uninjured pelvic bone (P < 0.0001). When different numbers (10(5), 5 x...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930560311
更新日期:1994-07-01 00:00:00
abstract::Metastatic liver disease is the commonest cause of death in patients with colorectal cancer. A small proportion of these patients (10%) may be treated by surgical resection with five year survival approaching 35-40%. Alternative treatment modalities for localised hepatic disease include in situ ablative techniques tha...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/1096-9098(200101)76:1<73::aid-jso1014>3.0.
更新日期:2001-01-01 00:00:00
abstract::Among women who have undergone surgery for breast cancer, the risk of recurrence, especially distant metastases, peaks 1-2 years postsurgery. Recent clinical trial evidence suggests that initial adjuvant therapy with an aromatase inhibitor (AI) can reduce this early risk of recurrence. According to the recently update...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.21801
更新日期:2011-06-01 00:00:00
abstract::Correlations between levels of tissue polypeptide antigen (TPA) in serum and histologic stage or progression of cancer were studied in 94 patients with gastric cancer. Levels of TPA in serum from patients with cancerous invasion into the vein of the stomach wall (v-invasion) were elevated in parallel to the progressio...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930410214
更新日期:1989-06-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The objectives of this study were to investigate the role of growth factors and matrix metalloproteinases in the brain metastasis. METHODS:Tumors from 40 patients with brain metastasis (30 lung cancer, 10 breast cancer) were studied to investigate the expression-patterns of EGFR, MT1-MMP, MMP...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21296
更新日期:2009-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The reported risk of nodal metastasis in hard palate and upper gingival squamous cell carcinoma (SCC) has been inconsistent with inadequate consensus regarding the utility of neck dissection in the clinically negative (cN0) neck. MATERIALS AND METHODS:Using the National Cancer Database, cN0 p...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25706
更新日期:2019-12-01 00:00:00
abstract::This paper reports on two patients, who both were under treatment for osteosarcoma of the femur. Treatment consisted of chemotherapy, resection of the tumour, and reconstruction with an endoprosthesis . Both patients sustained an epiphyseal fracture on two occasions after a minor trauma. Careful observations of the x-...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930260110
更新日期:1984-05-01 00:00:00
abstract::Cell surface sialic acid levels were compared for monocytes and macrophages obtained from normal volunteers and breast cancer patients. Equal quantities of sialic acid were found on the monocytes obtained from normal volunteers and breast cancer patients. Approximately 60% more cell surface sialic acid was found on th...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930220203
更新日期:1983-02-01 00:00:00
abstract::Type-2 adenovirus was shown to inhibit the growth of transplantable hamster melanoma in 70% of Syrian hamsters without any injurious effect to the host. Greatest inhibition of tumor formation was seen when animals were injected with 10(6) TCD50 of adenovirus and 2.5 x 10(5) tumor cells, or 10(6) TCD50 of virus and 5.0...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930070514
更新日期:1975-01-01 00:00:00