Consolidation hyperthermic intraperitoneal chemotherapy using paclitaxel in patients with epithelial ovarian cancer.

Abstract:

BACKGROUND:We evaluated the efficacy and feasibility of hyperthermic intraperitoneal chemotherapy (HIPEC) using paclitaxel as consolidation therapy in patients with epithelial ovarian cancer. METHODS:Between November 1999 and January 2004, 18 patients with a negative second-look and 1 patient with positive peritoneal cytology only with stage Ic-IIIc epithelial ovarian cancer received consolidation intra-operative HIPEC using paclitaxel. The HIPEC was performed with open-abdomen technique, using 6 L of lactated Ringer's solution containing paclitaxel 175 mg/m(2), for 90 min in hyperthermic phase (43-44 degrees C). The survival rates were compared with 24 patients treated with conventional therapy (control group). RESULTS:The 8-year progression-free survival rates were 63.16% in the HIPEC-paclitaxel group and 29.17% in the control group (P = 0.027). The 8-year overall survival rates were 84.21% in the HIPEC-paclitaxel group and 25.00% in the control group (P = 0.0004). The time interval between initial treatment and HIPEC was statistically significant with respect to progression-free and overall survival in the HIPEC-paclitaxel group. CONCLUSION:HIPEC with paclitaxel during 2nd-look laparotomy is feasible and relatively safe and showed a good effect on survival. In patients with epithelial ovarian cancer who have a complete pathologic response, HIPEC with paclitaxel should be considered as a consolidation treatment option.

journal_name

J Surg Oncol

authors

Kim JH,Lee JM,Ryu KS,Lee YS,Park YG,Hur SY,Lee KH,Lee SH,Kim SJ

doi

10.1002/jso.21448

subject

Has Abstract

pub_date

2010-02-01 00:00:00

pages

149-55

issue

2

eissn

0022-4790

issn

1096-9098

journal_volume

101

pub_type

临床试验,杂志文章
  • Laparoscopic resection for Bismuth type III and IV hilar cholangiocarcinoma: How to improve the radicality without direct palpation.

    abstract:BACKGROUND:Open surgery for hilar cholangiocarcinoma (HCCA) has already been widely reported and analyzed. However, the laparoscopic technique for treating HCCA remains controversial because of the lack of radicality and poor assessment of the resectability of hilar structures without direct palpation. The aim of this ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.25739

    authors: Feng F,Cao X,Liu X,Qin J,Zhang S,Li Q,Liu J

    更新日期:2019-12-01 00:00:00

  • Gastric cancer: biology and clinical manifestations in Israel.

    abstract:BACKGROUND:Gastric cancer (GC) in Israel remains incompletely characterized. The aim of this study was to define the clinical and pathological characteristics of GC in Israel and to compare them to the general Western population. PATIENTS AND METHODS:This is a retrospective analysis of 461 consecutive GC patients trea...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.22078

    authors: Dreznik A,Purim O,Idelevich E,Kundel Y,Sulkes J,Sulkes A,Brenner B

    更新日期:2012-03-01 00:00:00

  • Neoplasms in skin and subcutis over the breast, simulating breast neoplasms: case reports and literature review.

    abstract::Twenty cases of neoplasms in skin and subcutaneous tissue over the breast were reviewed. There were 17 women, from 15 to 70 years of age, and three men, from 25 to 66 years of age. Among the benign skin neoplasms, superficial leiomyoma, granular cell tumor, and eccrine acrospiroma were misdiagnosed clinically as prima...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930310312

    authors: Ilie B

    更新日期:1986-03-01 00:00:00

  • The role of adjuvant chemotherapy in stage II and III mucinous colon cancer.

    abstract:INTRODUCTION:Mucinous adenocarcinoma is a subtype of colonic adenocarcinoma associated with worse survival compared to nonmucinous adenocarcinoma. Prior studies on the effect of chemotherapy on survival in mucinous adenocarcinoma have shown mixed results. The aim of this study is to evaluate the effect of chemotherapy ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.25705

    authors: Fields AC,Lu P,Goldberg J,Irani J,Bleday R,Melnitchouk N

    更新日期:2019-12-01 00:00:00

  • Outcome after reconstruction of proximal femoral tumors: A systematic review.

    abstract::Tumor resection followed by reconstruction with a proximal femoral endoprosthesis or an allograft-prosthesis composite are the two main alternatives for treatment of proximal femoral malignancies. This review describes the revision rate, implant survival, limb salvage rate, and function. Overall revision rates are hig...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,meta分析

    doi:10.1002/jso.25297

    authors: Janssen SJ,Langerhuizen DWG,Schwab JH,Bramer JAM

    更新日期:2019-01-01 00:00:00

  • Profunda artery perforator flap for isolated vulvar defect reconstruction after oncological resection.

    abstract:UNLABELLED:Isolated vulvar reconstruction using profunda artery-based perforator flaps have good functional as well as quality of life restoration. Surgical techniques, complications, and final evaluation using questionnaires are presented. BACKGROUND:Vulvar reconstruction remains a great challenge to reconstructive s...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.24233

    authors: Chang TN,Lee CH,Lai CH,Wu CW,Chang CS,Cheng MH,Huang JJ

    更新日期:2016-06-01 00:00:00

  • Adjuvant external beam radiation for medullary thyroid carcinoma.

    abstract:BACKGROUND:Adjuvant radiation is rarely used to treat medullary thyroid carcinoma (MTC). We hypothesized that external beam radiation therapy (EBRT) would improve overall survival (OS) in MTC patients. METHODS:The Surveillance, Epidemiology, and End Results (SEER) database identified patients who underwent total thyro...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.21557

    authors: Martinez SR,Beal SH,Chen A,Chen SL,Schneider PD

    更新日期:2010-08-01 00:00:00

  • Alveolar soft part sarcoma metastatic to the breast.

    abstract::Metastasis to the breast is uncommon, with an incidence of 0.5-3%. Alveolar soft part sarcoma is rare, accounting for < 1% of malignant soft tissue tumors, which are themselves unusual. Excluding contralateral breast and hematologic malignant disease, the primary lesion in most cases of metastasis to the breast is mel...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/(SICI)1096-9098(199602)61:2<159::AID-JSO13

    authors: Hanna NN,O'Donnell K,Wolfe GR

    更新日期:1996-02-01 00:00:00

  • Fractal heterogeneity of peripheral blood flow: implications for hematogenous metastases.

    abstract:BACKGROUND AND OBJECTIVES:To determine how inhomogeneities in blood perfusion might affect the number of metastases that develop within an individual with cancer. METHODS:Experiments with lung metastases in mice, involving 320 treatment groups and 3165 mice, were reviewed. Inhomogeneities in the distribution of metast...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/1096-9098(200006)74:2<116::AID-JSO7>3.0.CO

    authors: Kendal WS

    更新日期:2000-06-01 00:00:00

  • An unusual late radiotherapy-related complication requiring surgery in anal canal carcinoma.

    abstract::We herein describe an unusual late radiation-related complication requiring surgery in a 60-year-old male affected by anal epidermoid carcinoma. The patient presented with obstructed defecation and ulcerated perianal lesions. The perianal biopsies were positive for anal squamous carcinoma. Transanal diagnostic investi...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/1096-9098(200006)74:2<167::AID-JSO17>3.0.C

    authors: Cicchini C,Stazi A,Ciardi A,Ghini C,Indinnimeo M

    更新日期:2000-06-01 00:00:00

  • Safety of rectum anastomosis after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.

    abstract:BACKGROUND AND OBJECTIVES:In highly selected patients with peritoneal carcinomatosis, cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) can be an aggressive but worthwhile treatment regimen. Resection of the rectosigmoid is frequently performed with CRS. The aim of the study wa...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.25189

    authors: von Breitenbuch P,Piso P,Schlitt HJ

    更新日期:2018-09-01 00:00:00

  • Lactation following conservation surgery and radiotherapy for breast cancer.

    abstract::A 38-year-old woman with early stage invasive breast cancer was treated with wide excision of the tumor, axillary lymph node dissection, and breast irradiation. Three years later, she gave birth to a normal baby. She attempted breast feeding and had full lactation from the untreated breast. The irradiated breast under...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930460214

    authors: Varsos G,Yahalom J

    更新日期:1991-02-01 00:00:00

  • Surgical management in metastatic gastrointestinal stromal tumor (GIST) patients after imatinib mesylate treatment.

    abstract:PURPOSE:Imatinib mesylate (IM) demonstrates substantial efficacy in most patients with metastatic gastrointestinal stromal tumors (GISTs). However, progression of GIST eventually develops and emerges as a challenge. To assess the role of surgery in the multidisciplinary management of GISTs, we studied the surgical outc...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.21630

    authors: Yeh CN,Chen TW,Tseng JH,Liu YY,Wang SY,Tsai CY,Chiang KC,Hwang TL,Jan YY,Chen MF

    更新日期:2010-11-01 00:00:00

  • Combining independently effective anticancer agents may not augment the independent antitumor effects: a study using human digestive organ cancer xenograft lines in nude mice.

    abstract::Five human digestive organ cancer xenograft lines were subcutaneously transplanted in nude mice, and 7 anticancer agents (ACAs) were intravenously administered singly or in combinations at 4 times the standard clinical doses. Cisplatin (P) was effective in 4 lines and 5-fluorouracil (F) was effective in 3 lines. A tot...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930480408

    authors: Nio Y,Tseng CC,Tsubono M,Kawabata K,Masai Y,Shiraishi T,Fukumoto M,Tobe T

    更新日期:1991-12-01 00:00:00

  • Granular cell tumor: a clinicopathologic study of 110 patients.

    abstract::The clinicopathologic features of 118 granular cell tumors (GCT) encountered at two affiliated hospitals were reviewed. A total of 110 patients were affected over this 32-year period of study (71 men, 39 women), and in 5% GCT were multiple. Patients ranged in age from 16 to 58 years (average 32 years) and were symptom...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930130405

    authors: Lack EE,Worsham GF,Callihan MD,Crawford BE,Klappenbach S,Rowden G,Chun B

    更新日期:1980-01-01 00:00:00

  • Spindle cell mucoepidermoid carcinoma of submandibular gland.

    abstract::A malignant tumor of the submandibular gland was found to consist predominately of spindle cell elements that initially suggested a primary sarcoma. Further examination revealed that the spindled malignant cells were derived from a high-grade mucoepidermoid carcinoma. ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930310116

    authors: Love GL,Sarma DP

    更新日期:1986-01-01 00:00:00

  • Nutritional management during neoadjuvant therapy for esophageal cancer.

    abstract::Patients undergoing neoadjuvant therapy for esophageal cancer are at a high risk for malnutrition due to the effects of chemoradiation, dysphagia, and malignancy induced cachexia. Preparation for esophagectomy requires careful assessment of nutritional risk and adequate supplementation as indicated. Supplementation vi...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.21289

    authors: Bower MR,Martin RC 2nd

    更新日期:2009-07-01 00:00:00

  • Semi-end-to-end esophagojejunostomy after laparoscopy-assisted total gastrectomy better reduces stricture and leakage than the conventional end-to-side procedure: A retrospective study.

    abstract:BACKGROUND AND OBJECTIVE:Laparoscopy-assisted total gastrectomy (LATG) has not gained popularity due to the technical difficulty of esophagojejunostomy (EJ) and the high incidence of EJ-related complications. Herein, we compared two types of EJ for Roux-en-Y reconstruction to determine whether semi-end-to-end (SETE) EJ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.24637

    authors: Duan W,Liu K,Fu X,Shen X,Chen J,Su C,Yu P,Zhao Y

    更新日期:2017-08-01 00:00:00

  • Incorporating resident/fellow training into a robotic surgery program.

    abstract::With the rapid uptake of the robotic approach in gynecologic surgery, a thorough understanding of the technology, including its uses and limitations, is critical to maximize patient outcomes and safety. This review discusses the role of training modalities and development of curricula for robotic surgery. Furthermore,...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.24006

    authors: Vetter MH,Green I,Martino M,Fowler J,Salani R

    更新日期:2015-12-01 00:00:00

  • Activation of matrix metalloproteinase-2 is correlated with invasiveness in thymic epithelial tumors.

    abstract:UNLABELLED:BACKGROUND AND OBJECTS: Matrix degradation, which is a critical event in the process of tumor invasion and metastasis, is considered to be caused by the action of proteolytic enzymes. METHODS:We examined the gelatinolytic activity of matrix metalloproteinase (MMP)-9, and the activity of active and inactive ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.1030

    authors: Kondo K,Kinoshita H,Ishikura H,Miyoshi T,Hirose T,Matsumori Y,Monden Y

    更新日期:2001-03-01 00:00:00

  • Variability of heating patterns in animals by magnetic induction hyperthermia.

    abstract::In a test of electromagnetic induction hyperthermia to deep viscera of a live dog model, we found that heating was not uniform to any depth, but was quite variable. In general, there was a thermal gradient between peripheral and central portions of the transposed spleen of about 1 degree C. Though heat generation with...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930290204

    authors: Storm FK,Christensen DA,Olch AJ,Silberman AW,Roe DJ,Harrison WH,Elliott RS,Morton DL

    更新日期:1985-06-01 00:00:00

  • Appraisal of disease-specific benefits of minimally invasiveness in surgery of breast cancer liver metastases.

    abstract:BACKGROUND:The primary endpoint of this study is to analyze short term benefit of laparoscopic approach (minimally invasive liver surgery [MILS]) over the open techniques in patients submitted to surgery for breast cancer liver metastases (BCLM) within a disease-specific perspective. MATERIAL AND METHODS:A group of 30...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.25702

    authors: Ratti F,Serenari M,Zanello M,Prosperi E,Cipriani F,Ercolani G,Jovine E,Cescon M,Aldrighetti L

    更新日期:2019-12-01 00:00:00

  • Therapeutic value of lymph node dissection for esophageal squamous cell carcinoma after neoadjuvant chemotherapy.

    abstract:BACKGROUND AND OBJECTIVES:The optimal extent of lymphadenectomy in patients with esophageal cancer is controversial. This study aimed to examine the therapeutic value of lymph node (LN) dissection for each LN station in patients with esophageal squamous cell carcinoma (ESCC) who receive neoadjuvant chemotherapy. METHO...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.23965

    authors: Miyata H,Yamasaki M,Makino T,Miyazaki Y,Takahashi T,Kurokawa Y,Nakajima K,Takiguchi S,Mori M,Doki Y

    更新日期:2015-07-01 00:00:00

  • Ethanol injection therapy in RBT-1 carcinoma of the rat liver evokes enhancement of metastasis.

    abstract::To search for possible untoward effects of ethanol injection into a malignant tumor, a series of experiments was carried out using the model of RBT-1 carcinoma. Ten days after the inoculation of RBT-1 carcinoma into the rat liver, the animals were separated into three groups: Group A, ethanol injection during relaparo...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930540105

    authors: Ikeda Y,Matsumata T,Adachi E,Nishizaki T,Sugimachi K

    更新日期:1993-09-01 00:00:00

  • Immunotherapy and whole-body hyperthermia as combined modality treatment of a subcutaneous murine sarcoma.

    abstract::Interleukin-2 and hyperthermia have been used individually to treat a variety of tumors in both experimental and human trials. Combined adoptive immunotherapy and hyperthermia is an exciting new line of investigation. Previous work in our laboratory has shown that combined local hyperthermia and rIL-2 therapy can sign...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930530310

    authors: Geehan DM,Fabian DF,Lefor AT

    更新日期:1993-07-01 00:00:00

  • Detubularized rectosigmoid neobladder in women after cystectomy for bladder cancer.

    abstract:BACKGROUND AND OBJECTIVES:We present the long-term functional results of a new technique for bladder substitution after cystectomy for bladder cancer in women. METHODS:Between 1991 and 1995, 10 women underwent radical cystectomy for bladder cancer with a new technique. We created a detubularized rectosigmoid neobladde...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/1096-9098(200005)74:1<49::aid-jso12>3.0.co

    authors: Mearini E,Mearini L,Zucchi A,Costantini E,Goracci G,Porena M

    更新日期:2000-05-01 00:00:00

  • Modified radical lymphadenectomy without splenectomy in patients with proximal gastric cancer: comparison with standard D2 lymphadenectomy for distal gastric cancer.

    abstract:BACKGROUND AND OBJECTIVES:We assessed the optimal extent of lymph node dissection and the effect of splenectomy in patients with proximal gastric cancer. METHOD:Recurrence and survival rates were compared between 881 patients with proximal gastric cancer who underwent modified radical lymphadenectomy and 3,098 patient...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.21137

    authors: Cheong O,Kim BS,Yook JH,Oh ST,Park YK,Ryu SY

    更新日期:2008-12-01 00:00:00

  • Hepatocellular carcinoma with a central scar and a scalloped tumor margin resembling focal nodular hyperplasia in macroscopic appearance.

    abstract:BACKGROUND:We sometimes encounter hepatocellular carcinoma (HCC) with a central scar and a scalloped tumor margin resembling focal nodular hyperplasia (FNH) in macroscopic appearance. The fibrolamellar variant sometimes shows this appearance; however, this type of HCC can be clearly differentiated from fibrolamellar va...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.20615

    authors: Yamamoto M,Ariizumi S,Yoshitoshi K,Saito A,Nakano M,Takasaki K

    更新日期:2006-12-01 00:00:00

  • Local treatment with electrochemotherapy of superficial angiosarcomas: Efficacy and safety results from a multi-institutional retrospective study.

    abstract:BACKGROUND:Angiosarcoma is an aggressive vascular neoplasm with a high propensity for local recurrence. Electrochemotherapy is an emerging skin-directed therapy, exerting prominent cytotoxic activity, and antivascular effects. Its efficacy in angiosarcoma has not been investigated. METHODS:This multicenter retrospecti...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.24287

    authors: Guida M,Campana LG,Curatolo P,Strippoli S,Bonadies A,Grilz G,Cabula C,Rotunno R,Bucher S,Solari N,Santoriello A,Valpione S,Rossi CR

    更新日期:2016-08-01 00:00:00

  • Early postoperative outcomes among patients with delayed surgeries after preoperative positive test for SARS-CoV-2: A case-control study from a single institution.

    abstract:BACKGROUND:There are limited data on surgical complications for patients that have delayed surgery after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We aimed to analyze the surgical outcomes of patients submitted to surgery after recovery from SARS-CoV-2 infection. METHODS:Asymptomatic pati...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.26377

    authors: Baiocchi G,Aguiar S Jr,Duprat JP,Coimbra FJF,Makdissi FB,Vartanian JG,Zequi SC,Gross JL,Nakagawa SA,Yazbek G,Diniz TP,Gonçalves BT,Zurstrassen CE,Campos HGDA,Joaquim EHG,França E Silva IA,Kowalski LP

    更新日期:2021-01-11 00:00:00