Combining independently effective anticancer agents may not augment the independent antitumor effects: a study using human digestive organ cancer xenograft lines in nude mice.

abstract：BACKGROUND AND OBJECTIVES:Accumulating epidemiological and molecular evidence suggests that inflammation is an important component in the etiology of PCa. Macrophage migration inhibitory factor (MIF) plays an important role in the pro- and anti-inflammatory response to infection. This study is aimed at investigating th...

journal_title：Journal of surgical oncology

authors： Ding GX,Zhou SQ,Xu Z,Feng NH,Song NH,Wang XJ,Yang J,Zhang W,Wu HF,Hua LX

更新日期：2009-08-01 00:00:00

abstract：:A case of spine metastasis of basal cell carcinoma and review of the literature are presented. The treatment approach is discussed. ...

journal_title：Journal of surgical oncology

authors： Weshler Z,Leviatan A,Peled I,Wexler M

更新日期：1984-01-01 00:00:00

abstract：:Munchausen's syndrome is a chronic factitious disorder characterized by frequent hospitalizations, self-inflicted injuries, and dramatic medical histories. People with this condition assume the role of a sick patient and submit to unnecessary invasive, painful, and even dangerous medical procedures. In review of the l...

journal_title：Journal of surgical oncology

authors： Bruns AD,Fishkin PA,Johnson EA,Lee YT

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:We evaluated whether electrothermal bipolar coagulation (Ligasure) for pelvic exenterations decreases operative morbidity. METHODS:All cases of pelvic exenterations, for all malignancies, performed at Moffitt Cancer Center from 1999 to 2008, were identified through retrospective review of medical records. E...

journal_title：Journal of surgical oncology

authors： Bansal N,Roberts WS,Apte SM,Lancaster JM,Wenham RM

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:The object of the current study was to review the outcomes of hepatic resection for hepatocellular carcinoma (HCC) ≥ 10 cm. METHODS:Between 1995 and 2007, fifty-three patients with HCC ≥ 10 cm underwent hepatic resection, and clinical data were compared to those of patients with non-surgical treatment (n = ...

journal_title：Journal of surgical oncology

authors： Yamashita Y,Taketomi A,Shirabe K,Aishima S,Tsuijita E,Morita K,Kayashima H,Maehara Y

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Unresectable tumors of the pancreatic head are encountered in up to 20% of patients taken for resection. The objective of this study was to evaluate the complications and outcome associated with palliative surgical procedures to help guide management decisions in these patients. METHODS:Patients with pancre...

journal_title：Journal of surgical oncology

authors： Spanheimer PM,Cyr AR,Liao J,Johlin FC,Hoshi H,Howe JR,Mezhir JJ

更新日期：2014-06-01 00:00:00

abstract：:A 65-year-old man presented with supraclavicular, mediastinal, and retroperitoneal lymphadenopathy clinically thought to be due to malignant lymphoma. Biopsy of a supraclavicular lymph node revealed metastatic adenocarcinoma positive for prostatic-specific antigen. This site of the primary tumor was confirmed by needl...

journal_title：Journal of surgical oncology

authors： Liel Y,Biderman A,Biran C,Katz M,Sacks M

更新日期：1987-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Uncertainty exists about the value of cancer therapy in patients aged 90 years and older. Because of the relative paucity of these patients, as well as the possibility of selection bias in any one institution, the use of a large, total population-based cancer registry was employed. METHODS:Th...

journal_title：Journal of surgical oncology

authors： Saltzstein SL,Behling CA

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:To determine the prognostic factors and to rationalize adjuvant therapy, the clinicopathologic data of patients with a stage II colon cancer were analyzed retrospectively. PATIENTS AND METHODS:A total of 392 patients underwent potentially curative resection at the Kurume University Hospital between 1982 and...

journal_title：Journal of surgical oncology

authors： Ogata Y,Murakami H,Sasatomi T,Ishibashi N,Mori S,Ushijima M,Akagi Y,Shirouzu K

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:We retrospectively evaluated the impact of postoperative complications on long-term outcomes after curative resection for colorectal cancer (CRC), using propensity-score analysis (PSA). PATIENTS AND METHODS:We reviewed data from 673 consecutive patients with stage I to III CRC, who underwent curative resecti...

journal_title：Journal of surgical oncology

authors： Miyamoto Y,Hiyoshi Y,Tokunaga R,Akiyama T,Daitoku N,Sakamoto Y,Yoshida N,Baba H

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:We present the long-term functional results of a new technique for bladder substitution after cystectomy for bladder cancer in women. METHODS:Between 1991 and 1995, 10 women underwent radical cystectomy for bladder cancer with a new technique. We created a detubularized rectosigmoid neobladde...

journal_title：Journal of surgical oncology

authors： Mearini E,Mearini L,Zucchi A,Costantini E,Goracci G,Porena M

更新日期：2000-05-01 00:00:00

abstract：:Efforts in lung cancer screening with chest X-ray (CXR) and sputum cytology in the 1970s and 1980s were negative. In the ensuing decade, the early lung cancer action project (ELCAP), and the Mayo screening study showed the promise of low-dose CT. These and other studies led to the National lung screening study (NLST),...

journal_title：Journal of surgical oncology

authors： Midthun DE,Jett JR

更新日期：2013-10-01 00:00:00

abstract：:A case of desmoid tumor of 17 years' duration associated with cystosarcoma phyllodes of 17 months' duration is presented. Good initial response to radiation therapy of the desmoid tumor was shown. Poor response of cytosarcoma phyllodes to radiation therapy was noted. A comparison between the similarities and differenc...

journal_title：Journal of surgical oncology

authors： Abadir R

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:Few studies have focused on distribution of lymph node metastasis. The aim of this study is to evaluate the prognostic significance of the location of involved lymph nodes in patients with advanced mid or low rectal cancer. METHODS:We defined proximal lymph node involvement (PLNp) as superior rectal and inf...

journal_title：Journal of surgical oncology

authors： Kim JS,Sohn DK,Park JW,Kim DY,Chang HJ,Choi HS,Oh JH

更新日期：2011-10-01 00:00:00

abstract：UNLABELLED:BACKGROUND AND OBJECTS: Matrix degradation, which is a critical event in the process of tumor invasion and metastasis, is considered to be caused by the action of proteolytic enzymes. METHODS:We examined the gelatinolytic activity of matrix metalloproteinase (MMP)-9, and the activity of active and inactive ...

journal_title：Journal of surgical oncology

authors： Kondo K,Kinoshita H,Ishikura H,Miyoshi T,Hirose T,Matsumori Y,Monden Y

更新日期：2001-03-01 00:00:00

abstract：:Extended lymphadenectomy has been proposed for loco-regional control of pancreatic adenocarcinoma. While retrospective series suggested a benefit, subsequent prospective trials have not shown a survival benefit. Methods to improve loco-regional control of pancreatic body/tail cancer have not been extensively investiga...

journal_title：Journal of surgical oncology

authors： Rupp CC,Linehan DC

更新日期：2009-03-15 00:00:00

abstract：:Cancer patients undergoing surgery often present with unusual and challenging problems. Their age and the fact that they are often chronically ill place them at increased surgical risk. In many instances the need for surgical intervention is crucial to the extent that risk-assessment becomes an academic issue, especia...

journal_title：Journal of surgical oncology

authors： Ewer MS,Ali MK

更新日期：1990-07-01 00:00:00

abstract：:The growth of knowledge and complexity now seen in General Surgery, has led to the sub-specialization of the discipline. Although it is considered by some to have led to the fragmentation of General Surgery and the erosion of the specialty as we know it today, others would argue that it has and will continue to lead t...

journal_title：Journal of surgical oncology

authors： Pasieka JL

更新日期：2005-03-01 00:00:00

abstract：:Breast cancers from 53 patients were explanted in culture, and 39 with two-year or more follow-up and documentable tissue forms of cancer in culture (histoculture) are the subject of this report. Clinicopathologic findings have been correlated with dynamic aspects of the cancers in short-term histocultures, including ...

journal_title：Journal of surgical oncology

authors： Sherwin RP,Richters A,Yellin AE,Donovan AJ

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:F-18 fluorodeoxyglucose-positron emission tomography (FDG-PET) has been used for diagnosis and staging of malignant diseases. However, the prognostic significance of FDG uptake on PET had not been sufficiently evaluated in patients with biliary carcinoma. METHODS:We performed a retrospective ...

journal_title：Journal of surgical oncology

authors： Furukawa H,Ikuma H,Asakura K,Uesaka K

更新日期：2009-11-01 00:00:00

abstract：:A total of 144 patients with advanced sarcomas were entered into a randomized prospective protocol with four treatment arms utilizing different combinations of chemotherapeutic agents. Of these, 120 patients (83%) were judged acceptable. Treatment 1: actinomycin-D (Act-D), 0.01 mg/kg IV, days 1--5; phenylalanine must...

journal_title：Journal of surgical oncology

authors： Cruz AB Jr,Thames EA Jr,Aust JB,Metter G,Ramirez G,Fletcher WS,Altman SJ,Frelick RW,Hill GJ 2nd

更新日期：1979-01-01 00:00:00

abstract：:Fibrosarcoma is a rare primary malignant tumor of the mediastinum. Three cases are presented with different presenting symptoms and clinical manifestations. Thoracotomy with biopsy of the mass is the only method for arriving at a definitive histologic diagnosis. ...

journal_title：Journal of surgical oncology

authors： Barua NR,Patel AR,Takita H,Jennings EC

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:X-linked inhibitor of apoptosis protein (XIAP) is a member of the inhibitor of apoptosis family of proteins and deregulation of XIAP can result in tumorigenicity. The objective of this study was to evaluate the prognostic significance of XIAP expression in colorectal cancer (CRC). METHODS:RT-PCR was perform...

journal_title：Journal of surgical oncology

authors： Xiang G,Wen X,Wang H,Chen K,Liu H

更新日期：2009-12-15 00:00:00

abstract：BACKGROUND:Locally advanced colon cancer can result in serious clinical conditions unless treated appropriately. The aim of this study was to examine the feasibility of en bloc resection and the significance of depth of invasion by analyzing the outcomes of the procedure in colon cancer invading adjacent organs. METHO...

journal_title：Journal of surgical oncology

authors： Oh SY,Kim YB,Paek OJ,Suh KW

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Cytoreductive surgery (CRS) and hyperthermic intra-peritoneal chemotherapy (HIPEC) treatment of colorectal peritoneal metastases (PM) is an established treatment alternative. The study aim was, first, to investigate the outcome of high-volume disease defined by the peritoneal cancer index (PCI) 20; second, t...

journal_title：Journal of surgical oncology

authors： Cashin PH,Dranichnikov F,Mahteme H

更新日期：2014-08-01 00:00:00

abstract：:We reviewed the literature concerning the effect of extended lymph node dissection on survival in patients with gastrointestinal cancer. Most retrospective and/or prospective nonrandomized comparative studies have claimed that extended lymph node dissection significantly improves survival rate in patients with esophag...

journal_title：Journal of surgical oncology

authors： Noguchi M,Miyazaki I

更新日期：1997-05-01 00:00:00

abstract：:Fifty-four patients with advanced upper gastrointestinal cancer were assessed for their nutritional status prior to any form of therapy. Anthropometric parameters--weight loss, arm muscle circumference, skin-fold thickness--and biochemical parameters--serum albumin and delayed cutaneous hypersensitivity reactions to p...

journal_title：Journal of surgical oncology

authors： Singh G,Khanna NN

更新日期：1985-08-01 00:00:00

abstract：:Perineural invasion is associated with tumor spreading and an unfavorable prognosis in a variety of cancers. Recently, neural cell adhesion molecule (NCAM) has been reported to be affinitive to neural tissues, which suggests some relationship between NCAM and perineural invasion. This study was designed to elucidate t...

journal_title：Journal of surgical oncology

authors： Seki H,Tanaka J,Sato Y,Kato Y,Umezawa A,Koyama K

更新日期：1993-06-01 00:00:00

abstract：:A patient-specific 3-dimensional printed model (3DPM) of a woman with breast cancer was created. Mastectomy was favored as BCS would necessitate significant breast size alteration due to the extent of disease. After review of the 3D printed model, the patient and surgeon agreed on breast-conserving surgery. Use of pat...

journal_title：Journal of surgical oncology

authors： Santiago L,Adrada BE,Caudle AS,Clemens MW,Black DM,Arribas EM

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Heme oxygenase-1 (HO-1) correlates with aggressive tumor behavior and chemotherapy resistance in pancreatic cancer (PC). We evaluated the prognostic value of the basal transcription controlling germ line GTn repeat polymorphism (GTn) in the promoter region of the HO-1 gene in PC. PATIENTS AND METHODS:We det...

journal_title：Journal of surgical oncology

authors： Vashist YK,Uzungolu G,Kutup A,Gebauer F,Koenig A,Deutsch L,Zehler O,Busch P,Kalinin V,Izbicki JR,Yekebas EF

更新日期：2011-09-01 00:00:00