Complications and survival associated with operative procedures in patients with unresectable pancreatic head adenocarcinoma.

Abstract:

BACKGROUND:Unresectable tumors of the pancreatic head are encountered in up to 20% of patients taken for resection. The objective of this study was to evaluate the complications and outcome associated with palliative surgical procedures to help guide management decisions in these patients. METHODS:Patients with pancreatic head adenocarcinoma taken to the operating room with curative intent who did not undergo pancreatectomy were evaluated. RESULTS:From 1997 to 2013, 50 patients were explored and found be unresectable due to M1 disease (n = 27, 54.0%) or vascular invasion (n = 23, 46.0%). Among unresectable patients, 34 (68.0%) had a palliative procedure performed including double bypass (n = 13), biliary bypass (n = 7), gastrojejunostomy (n = 5), or cholecystectomy (n = 9). Complications occurred in 22 patients (44.0%), and patients who had a palliative operation had a longer hospital stay and more major complications. Overall survival was reduced in patients treated with a palliative operation. CONCLUSIONS:Despite advancements in endoscopic palliation, operative bypasses are still commonplace in patients with unresectable pancreatic head cancer. In this study, patients treated with operative procedures had a high rate of complications without a notable improvement in outcome. These findings highlight the importance of identifying unresectable disease prior to surgery and support a selective approach to palliative operations.

journal_name

J Surg Oncol

authors

Spanheimer PM,Cyr AR,Liao J,Johlin FC,Hoshi H,Howe JR,Mezhir JJ

doi

10.1002/jso.23560

subject

Has Abstract

pub_date

2014-06-01 00:00:00

pages

697-701

issue

7

eissn

0022-4790

issn

1096-9098

journal_volume

109

pub_type

杂志文章
  • Robot-assisted retroperitoneal lymph node dissection in testicular cancer.

    abstract::Robotic surgical techniques are now being applied in the setting of retroperitoneal lymphadenectomy (RPLND) for testicular cancer. While laparoscopic RPLND has not been widely accepted, reports of robot assisted RPLND (RARPLND) are emerging. This manuscript will review the application of RPLND for testicular cancer, e...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.24018

    authors: Abdul-Muhsin HM,L'esperance JO,Fischer K,Woods ME,Porter JR,Castle EP

    更新日期:2015-12-01 00:00:00

  • Epididymal metastasis from prostatic cancer.

    abstract::A case of prostatic adenocarcinoma metastasizing to the epididymis is described, and the literature is reviewed. ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.2930240416

    authors: Sarma DP,Weiner M,Weilbaecher TG

    更新日期:1983-12-01 00:00:00

  • Cryosurgical ablation of unresectable hepatic metastases.

    abstract:BACKGROUND AND OBJECTIVES:Recent advancements in the technology of cryosurgery along with the development and refinement of intraoperative ultrasound have led to a feasible alternative for some patients with unresectable hepatic malignancy. This paper reports our first year's experience with cryosurgical ablation of un...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-9098(199808)68:4<242::aid-jso7>

    authors: Dale PS,Souza JW,Brewer DA

    更新日期:1998-08-01 00:00:00

  • Modified Harrington reconstruction for advanced periacetabular metastatic disease.

    abstract:BACKGROUND/OBJECTIVES:Destructive metastatic lesions about the acetabulum result in pain and functional limitations. We assessed whether periacetabular reconstruction (PAR) improves quality of life by examining outcome measures of pain, function, and mobility. METHODS:Thirty-seven patients with a mean follow-up of 23....

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.21440

    authors: Ho L,Ahlmann ER,Menendez LR

    更新日期:2010-02-01 00:00:00

  • Is there a role for second-look laparotomy in the management of malignant germ cell tumors of the ovary? Experience at Institut Gustave Roussy.

    abstract::The last two decades have seen great improvements in the management of patients with germ-cell tumors of the ovary. The initial treatment approach includes conservative surgery and cisplatin-based chemotherapy in most cases. At completion of chemotherapy, the role of second-look surgery remains questionable. We retros...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/(SICI)1096-9098(199605)62:1<40::AID-JSO9>3

    authors: Culine S,Lhomme C,Michel G,Leclere J,Duvillard P,Droz JP

    更新日期:1996-05-01 00:00:00

  • Mismatch repair status predicts survival after adjuvant treatment in stage II colon cancer patients.

    abstract:BACKGROUND AND OBJECTIVES:Stage II colon cancer is primarily a surgical disease. Only a still not well-defined subset of patients may benefit from postoperative adjuvant chemotherapy. The relationship between adjuvant chemotherapy and survival after relapse is furthermore still not definitely explored in this group of ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.25798

    authors: Gkekas I,Novotny J,Fabian P,Nemecek R,Palmqvist R,Strigård K,John S,Pecen L,Reginacova K,Gunnarsson U

    更新日期:2019-12-11 00:00:00

  • The intersection of tumor location and combined bowel preparation: Utilization differs but anastomotic leak risk reduction does not.

    abstract:BACKGROUND AND OBJECTIVE:Whether bowel preparation utilization rates or effectiveness varies based on tumor location is unknown. METHODS:The 2012-2016 American College of Surgeons National Surgical Quality Improvement Program Colectomy Targeted participant user file was queried for patients undergoing elective colorec...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.26224

    authors: McKenna NP,Bews KA,Colibaseanu DT,Mathis KL,Nelson H,Habermann EB

    更新日期:2021-01-01 00:00:00

  • National quality measurement using clinical indicators: the Danish National Indicator Project.

    abstract::This article describes the Danish National Indicator Project that aims to document and improve the quality of care at national level. Specific clinical indicators, standards, and prognostic factors have been developed for eight diseases (e.g. lung cancer). It has been implemented in all clinical departments in Denmark...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.21192

    authors: Mainz J,Hansen AM,Palshof T,Bartels PD

    更新日期:2009-06-15 00:00:00

  • Technique for placement of a totally implantable venous access device.

    abstract::A totally implantable venous access system is described which greatly improved the ability to gain long-term venous access in selected patients. The external jugular approach has been demonstrated to be a safe and simple technique. The only major problem associated with the implantable venous access system was the dev...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930370413

    authors: Kondi ES,Pietrafitta JJ,Barriola JA

    更新日期:1988-04-01 00:00:00

  • Validation of clinical prognostic scores for patients treated with curative-intent for recurrent colorectal liver metastases.

    abstract:BACKGROUND:Scoring systems were developed to stratify patients with colorectal liver metastases considered for liver resection into different risk groups. Such scores have never been evaluated in recurrent liver metastases. The aim of this study was to evaluate whether these scores are applicable to patients with recur...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.24959

    authors: Dupré A,Rehman A,Jones RP,Parker A,Diaz-Nieto R,Fenwick SW,Poston GJ,Malik HZ

    更新日期:2018-05-01 00:00:00

  • Adjuvant external beam radiation for medullary thyroid carcinoma.

    abstract:BACKGROUND:Adjuvant radiation is rarely used to treat medullary thyroid carcinoma (MTC). We hypothesized that external beam radiation therapy (EBRT) would improve overall survival (OS) in MTC patients. METHODS:The Surveillance, Epidemiology, and End Results (SEER) database identified patients who underwent total thyro...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.21557

    authors: Martinez SR,Beal SH,Chen A,Chen SL,Schneider PD

    更新日期:2010-08-01 00:00:00

  • Over-expression of LAPTM4B is associated with poor prognosis and chemotherapy resistance in stages III and IV epithelial ovarian cancer.

    abstract:BACKGROUND:The purpose of this study was to determine whether LAPTM4B over-expression is associated with the prognosis and chemotherapy resistance in patients with stages III and IV epithelial ovarian carcinoma, i.e., patients with peritoneal metastasis or lymph node metastasis of epithelial ovarian carcinoma. METHODS...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.21912

    authors: Yin M,Li C,Li X,Lou G,Miao B,Liu X,Meng F,Zhang H,Chen X,Sun M,Ling Q,Zhou R

    更新日期:2011-07-01 00:00:00

  • Overall survival by pattern of recurrence following curative intent surgery for colorectal liver metastasis.

    abstract:BACKGROUND:Following curative intent surgery (CIS) for colorectal liver metastasis (CRLM), patterns of recurrence and subsequent survival outcomes are not widely reported. METHODS:An institutional database (January 2002-December 2012) was reviewed to evaluate patterns of recurrence following CIS for CRLM. RESULTS:163...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.23756

    authors: Kulaylat AN,Schubart JR,Stokes AL,Bhayani NH,Wong J,Kimchi ET,O'Carroll KF,Kaifi JT,Gusani NJ

    更新日期:2014-12-01 00:00:00

  • Epiphyseal fractures in children treated for osteosarcoma of the femur with chemotherapy, tumourresection, and endoprosthesis: report of four fractures in two children.

    abstract::This paper reports on two patients, who both were under treatment for osteosarcoma of the femur. Treatment consisted of chemotherapy, resection of the tumour, and reconstruction with an endoprosthesis . Both patients sustained an epiphyseal fracture on two occasions after a minor trauma. Careful observations of the x-...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930260110

    authors: Veth RP,De Graaf SS,Den Heeten GJ,Oldhoff J,Hoekstra HJ,Schraffordt Koops H,Nielsen HK

    更新日期:1984-05-01 00:00:00

  • Safety and early efficacy of irreversible electroporation for hepatic tumors in proximity to vital structures.

    abstract:INTRODUCTION:Irreversible electroporation (IRE) has shown promise for ablation of lesions in proximity to vital structures in the preclinical setting. This study aims to evaluate the safety and efficacy of IRE for hepatic tumors in the clinical setting. METHODS:An IRB approved prospective registry of patients undergoi...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.23280

    authors: Cannon R,Ellis S,Hayes D,Narayanan G,Martin RC 2nd

    更新日期:2013-04-01 00:00:00

  • Impact of screening mammography and change in surgeons' attitudes on the pattern of primary care of breast cancer at a community hospital.

    abstract::To gauge the impact of screening mammography and opinions regarding surgical procedures on the pattern of primary surgical care of breast cancer, tumor registry statistics from 1980-81 were compared to those from 1987 at a large community hospital. Over the course of six years, there was a significant increase in the ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930450104

    authors: Goldsweig HG,O'Sullivan M

    更新日期:1990-09-01 00:00:00

  • Comparison of open and closed abdomen techniques for the delivery of intraperitoneal pemetrexed using a murine model.

    abstract:BACKGROUND AND OBJECTIVES:Pemetrexed is an appealing agent to use for cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC). However, the optimal method of pemetrexed delivery still remains undefined. Using a murine model, we compared the use of open and closed abdomen techniques on the absorptio...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.24960

    authors: Badrudin D,Sideris L,Perrault-Mercier C,Hubert J,Leblond FA,Dubé P

    更新日期:2018-05-01 00:00:00

  • Changes in the body image of bone sarcoma survivors following surgical treatment--A qualitative study.

    abstract:BACKGROUND AND OBJECTIVES:Among several long-term effects, people treated for cancer may experience an altered appearance. Our study aims to identify how visible body changes following surgical treatment affect the life and identity of primary bone sarcoma survivors 3-10 years after diagnosis. A qualitative, phenomenol...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.24138

    authors: Fauske L,Lorem G,Grov EK,Bondevik H

    更新日期:2016-02-01 00:00:00

  • Breast cancer surgery-induced immunomodulation.

    abstract:BACKGROUND AND OBJECTIVES:Surgical procedures can cause tumor cells to disseminate into the circulatory system. Although this spread of metastatic cells will be limited by immune activity, immunosuppression tends to be the main effect resulting from surgery. The objective of this study is to assess hormonal and immunol...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.21662

    authors: Boomsma MF,Garssen B,Slot E,Berbee M,Berkhof J,Meezenbroek Ede J,Slieker W,Visser A,Meijer S,Beelen RH

    更新日期:2010-11-01 00:00:00

  • Locally recurrent rectal cancer: role of composite resection of extensive pelvic tumors with strategies for minimizing risk of recurrence.

    abstract::Locally recurrent cancer of the rectum has been under-recognized as a complication, although it affects up to 40% of patients treated with surgery alone. Even in the best centers, rates average 25%. While radiotherapy may reduce recurrence, it is now apparent that total mesorectal excision is the most effective modali...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/(sici)1096-9098(200001)73:1<47::aid-jso12>

    authors: Temple WJ,Saettler EB

    更新日期:2000-01-01 00:00:00

  • Prognostic significance of distribution of lymph node metastasis in advanced mid or low rectal cancer.

    abstract:BACKGROUND:Few studies have focused on distribution of lymph node metastasis. The aim of this study is to evaluate the prognostic significance of the location of involved lymph nodes in patients with advanced mid or low rectal cancer. METHODS:We defined proximal lymph node involvement (PLNp) as superior rectal and inf...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.21966

    authors: Kim JS,Sohn DK,Park JW,Kim DY,Chang HJ,Choi HS,Oh JH

    更新日期:2011-10-01 00:00:00

  • When is hemiarthroplasty preferable to intramedullary prophylactic fixation of malignant lesions of the proximal femur?

    abstract:BACKGROUND:Malignant hip lesions can be managed operatively by intramedullary (IM) nail fixation and hemiarthroplasty. METHODS:A retrospective review was performed on 86 patients who underwent hemiarthroplasty (n = 22) or IM nail fixation (n = 64) for prophylactic treatment of impending pathologic fracture due to mali...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.24792

    authors: Lin JS,Santiago-Torres JE,Everhart JS,Zayan NE,Mayerson JL,Scharschmidt TJ

    更新日期:2017-12-01 00:00:00

  • Robotic trans-axillary and retro-auricular thyroid surgery.

    abstract::Remote access approaches for thyroid surgery using surgical incisions placed outside the neck, including the axillary, chest and the retro-auricular region have gained interest due to the social stigmatization of young females with a visible neck scar. These novel approaches have been reported to be safe and feasible ...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1002/jso.23955

    authors: Mohamed HE,Kandil E

    更新日期:2015-09-01 00:00:00

  • Pathologic fracture does not influence local recurrence and survival in high-grade extremity osteosarcoma with adequate surgical margins.

    abstract:BACKGROUND AND OBJECTIVES:The purpose of this study was to estimate the risk factors having relationships with pathologic fracture of osteosarcoma of extremities and to evaluate the role of limb salvage surgery in this group of patients. METHODS:We retrospectively analyzed 28 consecutive cases of pathologic fracture o...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.23150

    authors: Xie L,Guo W,Li Y,Ji T,Sun X

    更新日期:2012-12-01 00:00:00

  • Surgical excision margin for primary acral melanoma.

    abstract:BACKGROUND AND OBJECTIVES:This study aimed to evaluate treatment outcomes of acral melanoma (AM) based on the excision margin. METHODS:A retrospective cohort study was conducted for patients with primary AM, analyzing recurrence rates, local and in-transit recurrence-free survival (LITRFS), disease-free survival (DFS)...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.24442

    authors: Lee KT,Kim EJ,Lee DY,Kim JH,Jang KT,Mun GH

    更新日期:2016-12-01 00:00:00

  • Tumor bed implant brachytherapy for residual carcinoma after palliative esophagectomy.

    abstract::Twenty-six patients with esophageal carcinoma at stage pT4 underwent esophagectomy with lymph node dissection leaving part of the tumor in adjacent organs. Several plastic catheters were fixed to the tumor bed and led to the outside of the thorax for postoperative brachytherapy. Using these catheters, the patients und...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/(SICI)1096-9098(199607)62:3<214::AID-JSO12

    authors: Kato H,Kagami Y,Tachimori Y,Watanabe H,Ikeda H

    更新日期:1996-07-01 00:00:00

  • Factors predictive for long-term survival of male patients with hepatocellular carcinoma after curative resection.

    abstract:BACKGROUND AND OBJECTIVES:Curative hepatic resection (CHR) was a modality that provides possibility of long-term survival for hepatocellular carcinoma (HCC). So far, prognostic factors of male patients with HCC after CHR remain unclear. Purposes of the present study were to identify these factors and to compare them wi...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.20678

    authors: Zhou L,Rui JA,Wang SB,Chen SG,Qu Q,Chi TY,Wei X,Han K,Zhang N,Zhao HT

    更新日期:2007-03-15 00:00:00

  • Hospice utilization among Medicare beneficiaries dying from pancreatic cancer.

    abstract:BACKGROUND:Use of hospice services among patients with pancreatic cancer following pancreatic resection remains unknown. METHODS:Patients with pancreatic cancer who underwent resection were identified in the Medicare Standard Analytic Files. Outcomes included overall hospice use, early hospice enrollment (≥4 weeks bef...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.25623

    authors: Paredes AZ,Hyer JM,Tsilimigras DI,Mehta R,Sahara K,White S,Dillhoff ME,Ejaz A,Cloyd JM,Pawlik TM

    更新日期:2019-09-01 00:00:00

  • Limb-sparing treatment with surgery and intraoperative radiotherapy (IORT) for a second local recurrence of myxoid liposarcoma in the popliteal region, after previous surgery and high-dose radiation.

    abstract::A 46-year-old man with a second local recurrence of a myxoid liposarcoma in the fossa poplitea, after surgery and high-dose external beam radiotherapy, was successfully treated by a limb-sparing procedure combining marginal excision, intraoperative radiotherapy and reconstructive surgery. After a 48-month follow-up, t...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.2930530116

    authors: Wijffels RT,Mehta DM,Spauwen PH,Hoekstra HJ

    更新日期:1993-05-01 00:00:00

  • Patient reasoning in palliative surgical oncology.

    abstract:BACKGROUND:The purpose of this study was to determine the patient reasoning behind treatment choice after palliative surgical consultation. METHODS:Patients undergoing palliative surgical consultation were prospectively enrolled in this observational cohort study (11/2009-5/2011) and administered an open-ended questio...

    journal_title:Journal of surgical oncology

    pub_type: 杂志文章

    doi:10.1002/jso.23215

    authors: Collins LK,Goodwin JA,Spencer HJ,Guevara C,Ferrell B,McSweeney J,Badgwell BD

    更新日期:2013-03-01 00:00:00