Abstract:
:Cancer patients undergoing surgery often present with unusual and challenging problems. Their age and the fact that they are often chronically ill place them at increased surgical risk. In many instances the need for surgical intervention is crucial to the extent that risk-assessment becomes an academic issue, especially for those patients whose only reasonable chance for either cure or palliation of unbearable disease is surgery. However, the internist's role in these situations often has preoperative, intraoperative, and postoperative ramifications. Preoperatively, the internist assesses operative risk and intervenes, when possible, to reduce the likelihood of surgical complications. Patients who clearly cannot survive surgery may be identified and channeled to other treatment modalities. Intraoperatively, the internist may be called upon to help with the management of acute organ failure, cardiac arrest, or vascular collapse. Following surgery, the internist may help by managing cardiopulmonary problems and treating infectious complications. The critical care internist is therefore an important member of the perioperative team and often provides valuable expertise, which can help to identify and treat problems expediently.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Ewer MS,Ali MKdoi
10.1002/jso.2930440312subject
Has Abstractpub_date
1990-07-01 00:00:00pages
185-90issue
3eissn
0022-4790issn
1096-9098journal_volume
44pub_type
杂志文章,评审abstract:BACKGROUND:Angiosarcoma is an aggressive vascular neoplasm with a high propensity for local recurrence. Electrochemotherapy is an emerging skin-directed therapy, exerting prominent cytotoxic activity, and antivascular effects. Its efficacy in angiosarcoma has not been investigated. METHODS:This multicenter retrospecti...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24287
更新日期:2016-08-01 00:00:00
abstract::For extremity soft tissue sarcomas, limb salvage is now standard of care. The extent of surgical margins is balanced with functionality of the resected limb. Although negative margins are the goal, the necessary width is unclear. Additional considerations for margin adequacy include presence of anatomic barriers such ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.24112
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND:Mutation of the KRAS oncogene (mKRAS) in colorectal cancer has been associated with aggressive tumor biology, resistance to epidermal growth factor inhibitors, and decreased overall survival (OS). The aim of the current study was to analyze the association of mKRAS with pathologic complete response (pCR) and...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.26244
更新日期:2021-01-01 00:00:00
abstract::Infertility because of testicular damage is a distressing problem for survivors of cancer chemotherapy. We have previously described a cytoprotective effect of temporary testicular circulatory isolation (TCI) during doxorubicin administration in the rat. In this report we define the relationship between duration of TC...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930390410
更新日期:1988-12-01 00:00:00
abstract::For 38 consecutive patients presenting with breast masses we compared accuracy of diagnosis, before biopsy, of the techniques of clinical examination, bilateral xeromammography, and aspiration cytology with a 10-cc syringe and a 22-gauge needle. Of the 38 patients, nine had carcinoma and 29 had benign breast disease. ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930120409
更新日期:1979-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:This study assessed the outcomes of Yttrium-90 (90 Y) radiation segmentectomy for hepatic metastases unamenable to resection or ablation. MATERIALS AND METHODS:Over 6 years, 36 patients with 53 tumors underwent segmental radioembolization. Patients were not candidates for surgical resection o...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,多中心研究
doi:10.1002/jso.26223
更新日期:2021-01-01 00:00:00
abstract::Tumor-associated antigen(s) from a specimen of human malignant melanoma and from spent culture medium of a melanoma cell line were extracted and purified. The incidence of antibody activity to these antigens, in sera from cancer patients with neoplasms of various histologic types, was higher (65--83%) than normal dono...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930130112
更新日期:1980-01-01 00:00:00
abstract::Since February, 1977, 735 patients having a history of receiving radiation therapy for benign conditions of the head and neck areas during infancy and childhood were examined in a thyroid screening program, and 159 patients were found to have palpable thyroid nodules. These patients had thyroid function tests and indi...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930140316
更新日期:1980-01-01 00:00:00
abstract::"Taking less treating better" has been one of the major improvements of breast cancer surgery in the last four decades. The application of this principle translates into equivalent survival of breast cancer conserving treatment (BCT) when compared to mastectomy, with a better cosmetic outcome. While it is relatively e...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.23596
更新日期:2014-07-01 00:00:00
abstract::Fibrosarcoma is a rare primary malignant tumor of the mediastinum. Three cases are presented with different presenting symptoms and clinical manifestations. Thoracotomy with biopsy of the mass is the only method for arriving at a definitive histologic diagnosis. ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930120103
更新日期:1979-01-01 00:00:00
abstract:AIMS:Establish oncologic safety using 50 Gy to sterilize tumor bearing bone before reimplantation in primary diaphyseal high grade extremity tumors, determine extracorporeal radiotherapy (ECRT) graft survival, and analyze factors that affect union at osteotomy sites. MATERIALS AND METHODS:Seventy non metastatic patien...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25092
更新日期:2018-07-01 00:00:00
abstract::The sentinel node (SN) is defined as the first draining node from the primary lesion and it has proven to be a good indicator of the metastatic status of regional lymph nodes in solid tumors. In the past 5 years, the validity of SN concept for gastric cancer has been demonstrated by a number of single institutional st...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.20220
更新日期:2005-06-01 00:00:00
abstract::Intra-abdominal visceral sarcomas are a rare group of mesenchymal tumors that require the use of distinct surgical principles and a multidisciplinary approach in order to optimize treatment. Surgery remains the only potentially curative treatment. Management and outcomes vary for the different sarcomas arising from vi...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23803
更新日期:2015-04-01 00:00:00
abstract::Intrapancreatic extension of pancreatic duct cell carcinoma in 19 resectable cases was evaluated by both hematoxylin and eosin (H&E) staining and quick immunostaining using antibodies against cancer-associated antigens--e.g., CA19-9, DUPAN 2, and CEA--on the intraoperative frozen-section biopsy during the course of la...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930400105
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Desmoplastic melanoma (DM) is a rare variant of cutaneous melanoma. Our goal was to study the surgical management of DM, identify prognostic factors, and impact of treatment options. METHODS:Patients with DM (n = 1,735) were identified from the Surveillance, Epidemiology, and End Results data...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21778
更新日期:2011-02-01 00:00:00
abstract::Two unusual presentations of perforated mucoid adenocarcinoma of the appendix are described. One patient presented with a large periappendicular abscess that extended into the gluteal region, the other with a retroperitoneal abscess and abscesses in the right flank and groin. Recognition of the source of the abscess m...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930250409
更新日期:1984-04-01 00:00:00
abstract::Fresh homogenized mammary gland adenocarcinoma (C3HBA) material was subcutaneously inoculated in the anterior right thigh of transplant host mice (C3H/HeJ). When tumors were palpable, the mice were separated into three groups. The test group received biweekly intratumoral injections of Mycobacterium ulcerans filtrate ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930110210
更新日期:1979-01-01 00:00:00
abstract:BACKGROUND:In this non-randomized study we aimed to assess the efficacy of the addition of low molecular weight heparin (LMWH) to gemcitabine (GEM) plus cisplatinum (CDDP) combination chemotherapy on survival by prevention of thromboembolic complications in patients with advanced pancreatic cancer (APC). PATIENTS AND ...
journal_title:Journal of surgical oncology
pub_type: 临床试验,杂志文章
doi:10.1002/jso.20728
更新日期:2007-05-01 00:00:00
abstract::This is a retrospective study of 462 patients who had masectomy and axillary dissection for carcinoma of the breast during 1971-1980. Actuarial analysis of relapse rates up to 5 years showed that the extent of involvement of axillary lymph nodes was the most important prognostic factor. Among patients without any axil...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930270109
更新日期:1984-09-01 00:00:00
abstract::A case of symptomatic granular cell tumor of the esophagus is described. Another 32 cases collected from the English literature are analyzed. The reported cases have occurred mostly in women of less than 50 years of age presenting with dysphagia. Excision of the lesion is curative. ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930330409
更新日期:1986-12-01 00:00:00
abstract::Mice with intravesical urothelial tumors (MBT-2) were challenged with E coli inoculated intravesically. Adherence of bacteria measured at 15 min or persistent infection at 24 h was significantly greater in the tumor-bearing bladders than in normal non-tumor-bearing mice. The tumor-bearing portion of the bladder contai...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930230405
更新日期:1983-08-01 00:00:00
abstract::This report reviews the methods and goals of treatment of gastrointestinal stromal tumor (GIST), the most common mesenchymal tumor of the gastrointestinal tract. GISTs express CD117, which serves as an immunohistochemical diagnostic marker. Surgical excision is the definitive treatment for all primary GISTs greater th...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.21030
更新日期:2008-12-15 00:00:00
abstract:BACKGROUND:The Goldilocks mastectomy procedure involves local contouring of completely autologous breast tissue created by preserving and de-epithelializing the residual mastectomy flaps. The purpose of this study was to provide outcomes data for 96-Goldilocks mastectomy procedures analyzing indications, complications,...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25465
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:Some cases of mass-forming intrahepatic cholangiocarcinoma (ICC) are diagnosed as hepatocellular carcinoma (HCC) based on preoperative imaging and clinical findings. We investigated the backgrounds of such cases. METHODS:Sixty-seven patients with mass-forming ICC underwent surgery from 1980 to 2002. Twenty-...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20091
更新日期:2004-08-01 00:00:00
abstract::From 1974 to 1985, 161 patients were followed by at least one colonoscopy following a polypectomy for an adenomatous polyp. These patients had had a previous curative resection performed for colorectal carcinoma. The median follow-up time after surgery was 54 months. A polyp within 65 cm from the anal verge or from a ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930380204
更新日期:1988-06-01 00:00:00
abstract::Serum copper levels (SCL) have been done in 106 patients of squamous cell carcinoma of the cervix and in 15 cases of local recurrences. The mean SCL has been significantly elevated in them in comparison to controls (P less than 0.001). The SCL falls to near normal range following successful therapy. There is a trend t...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930220313
更新日期:1983-03-01 00:00:00
abstract::Treatment of gastric cancer has evolved with the advent of randomized trials demonstrating chemotherapeutic agents with efficacy in advanced disease. Level I evidence supports delivering chemotherapy in the neoadjuvant setting; the data shows improvement in progression-free and overall survival. A clinical response to...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.21483
更新日期:2010-03-15 00:00:00
abstract:BACKGROUND:Peritonectomy combined with perioperative intraperitoneal chemotherapy is a successful treatment option for patients with peritoneal dissemination of appendiceal and colorectal malignancy. Despite its efficacy, recurrences remain a common problem. METHODS:Patients with peritoneal dissemination from appendic...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21084
更新日期:2008-09-15 00:00:00
abstract::Depending on the local extension of primary non-small cell lung cancer (NSCLC) and invaded T4 structure(s), 49 patients underwent complete (CR, n = 14) or palliative (PR, n = 13) resection of exploratory thoracotomy (ET, n = 22) between January 1982 and June 1988. Thoracic radiotherapy (TR) was given to all patients r...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930470402
更新日期:1991-08-01 00:00:00
abstract::Lymph node status is not part of the staging system for cervical cancer, but provides important information for prognosis and treatment. This article reviews the incidence and patterns of lymph node metastasis, and the issues surrounding surgical assessment of lymph nodes. The preoperative assessment of lymph nodes by...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.21199
更新日期:2009-03-15 00:00:00