Neoadjuvant therapy of locally advanced gastric cancer.

Abstract:

:Treatment of gastric cancer has evolved with the advent of randomized trials demonstrating chemotherapeutic agents with efficacy in advanced disease. Level I evidence supports delivering chemotherapy in the neoadjuvant setting; the data shows improvement in progression-free and overall survival. A clinical response to therapy is associated with improved R0 resection rates, pathologic response, and outcome in patients with locally advanced disease. Early assessment of metabolic response to therapy can potentially be utilized to tailor treatment.

journal_name

J Surg Oncol

authors

Mezhir JJ,Tang LH,Coit DG

doi

10.1002/jso.21483

subject

Has Abstract

pub_date

2010-03-15 00:00:00

pages

305-14

issue

4

eissn

0022-4790

issn

1096-9098

journal_volume

101

pub_type

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