New intraoperative brachytherapy techniques for positive or close surgical margins.

Abstract:

:Tumors attached or adjacent to critical structures can often not be completely resected or resected with adequate surgical margins. Sites involving major blood vessels, the paravertebral spaces, or critical abdominal structures often present technical difficulties for standard brachytherapy procedures using I-125 or Ir-192 implants. These techniques allow for a high-dose delivery to the tumor bed with minimal normal tissue toxicity. A relatively simple and accurate method is described using I-125 seeds in Vicryl suture threaded through Gelfoam. These permanent implant procedures with radioactive I-125 seeds effectively treat small residual tumors or suspicious margins where standard brachytherapy techniques may be unsatisfactory and technically difficult to perform.

journal_name

J Surg Oncol

authors

Nori D,Bains M,Hilaris BS,Harrison L,Fass D,Peretz T,Donath D,Fuks Z

doi

10.1002/jso.2930420112

subject

Has Abstract

pub_date

1989-09-01 00:00:00

pages

54-9

issue

1

eissn

0022-4790

issn

1096-9098

journal_volume

42

pub_type

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