Abstract:
BACKGROUND AND OBJECTIVES:Tall cell (TCV), columnar cell (CCV), insular (IC), diffuse sclerosing (DSPTC) and solid/trabecular are uncommon subtypes of thyroid cancer, which have generally been described in case reports or small series in the world literature. Due to the rarity of these thyroid cancers, their clinical behavior remains incompletely understood. The aim of this review was to pool the currently available clinical information regarding these uncommon thyroid cancers so as to gain a better understanding of their clinical aspects and natural history. METHODS:A computer-aided search of MEDLINE (1966-2001, PUBMED website) and CINAHL (1982-2001) databases was performed, as well as a review of the reference section of each primary study was done. All cases of TCV, CCV, DSPTC, solid/trabecular, and IC described in the English medical literature were identified. For the subtypes DSPTC, TCV, and IC, clinical data from the published case series were combined in a weighted analysis. Weighting was based on the number of cases per series. For the CCV and the solid/trabecular variant, due to the small number of cases, raw figures for the clinical features were obtained. RESULTS:DSPTC (n = 65) appeared to have a tendency for intra-thyroidal extension (40%) and a high propensity for nodal metastates (68%). The mean overall tumor related mortality was similar to well differentiated thyroid cancer (WDTC) at only 2% at 8 years follow-up. The solid/trabecular variant was seen in 37% of the radiation induced thyroid tumors of the Chernobyl accident. It had a high propensity for extrathyroidal extension, and cervical lymph node metastases were found in up to 83% of patients. Unlike WDTC, TCV (n = 209) was a more aggressive tumor, associated with distant metastases in 22% of cases and had a mean tumor related mortality of 16%. The histological diagnosis of TCV was a poor prognostic factor regardless of patient age or tumor size. The CCV (n = 41) had a high overall mortality rate of 32%. When encapsulated, however, CCV had an excellent prognosis similar to that found in WDTC. In contrast, CCV tumors that were not encapsulated had extrathyroidal spread in 67% and had distant metastases in 87% of patients. The variant of IC (n = 213) appeared to be an aggressive subtype of thyroid cancer. The mean loco-regional recurrence and/or distant metastases rate was 64% and tumor related mortality was high at 32%. CONCLUSIONS:DSPTC, TCV, CCV, and IC are thyroid cancer subtypes, which have a biological aggressiveness, which appear to be intermediate between that of WDTC and poorly differentiated anaplastic thyroid cancer. J. Surg. Oncol. 2004;86:44-54.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Sywak M,Pasieka JL,Ogilvie Tdoi
10.1002/jso.20044subject
Has Abstractpub_date
2004-04-01 00:00:00pages
44-54issue
1eissn
0022-4790issn
1096-9098journal_volume
86pub_type
杂志文章,评审abstract::Six hundred sixty-eight patients with tumours of the larynx were treated by radiotherapy. The patients had stage T1 N0 M0 to T4 N3 M0 disease. Patients with T1 N0 M0 disease (273) had an excellent long-term survival (90%) as did those with T2 N0 M0 disease (142), whose 5-year survival was 70%. Patients with more advan...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930350402
更新日期:1987-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Immune status in the peritoneal cavity of patients with gastric cancer remains largely unknown. To clarify the clinical significance of the host immune response within the peritoneal cavity, we examined the levels of interferon-gamma (IFN-gamma), a type 1 cytokine, and interleukin-10 (IL-10), ...
journal_title:Journal of surgical oncology
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doi:10.1002/jso.1131
更新日期:2001-10-01 00:00:00
abstract::Supernatant fluids from three human cultured cell lines, K562, NALM-1, and Daudi, all isolated from patients with lymphoreticular malignancies, were tested for suppressive activity toward normal lymphocytes in vitro. It was found that the K562 line elaborated material which effectively suppressed the response of norma...
journal_title:Journal of surgical oncology
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doi:10.1002/jso.2930230106
更新日期:1983-05-01 00:00:00
abstract:BACKGROUNDS AND OBJECTIVES:The aim of this study was to describe the epidemiology and treatment of skin adnexal carcinoma (SAC) in the Netherlands and to identify prognostic factors for survival in patients with SAC. METHODS:We used population-based nationwide data from the Netherlands Cancer Registry with cases diagn...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23331
更新日期:2013-06-01 00:00:00
abstract::Seventy tumors of invasive ductal carcinoma of the breast were examined for p53 alteration by the RT-PCR-SSCP method. Sixty-five samples (92.9%) were investigated in the regions of codons 101-200 and 201-300. In total, 16 samples (24.6%) showed p53 gene alteration. We found that p53 gene alteration showed a correlatio...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930560110
更新日期:1994-05-01 00:00:00
abstract::A case of prostatic adenocarcinoma metastasizing to the epididymis is described, and the literature is reviewed. ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.2930240416
更新日期:1983-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Hepatic arterial infusion (HAI) chemotherapy offers improved hepatic control for liver metastases from colon cancer. Optimal catheter insertion requires an adequate gastroduodenal artery (GDA). Limited data exists on using saphenous vein grafts (SVG) as conduits when native vasculature is inad...
journal_title:Journal of surgical oncology
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doi:10.1002/jso.20890
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Arterial resection (AR) has traditionally been considered as a contraindication to pancreatic resection for locally advanced pancreatic adenocarcinoma. The objective was to evaluate if pancreatic resection with AR was worthwhile. METHODS:Between January 1990 and December 2008 the records of 2...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21769
更新日期:2011-01-01 00:00:00
abstract::We studied the influence of surgical trauma to the iliac bone on the implantation of I.V. injected tumor cells, which formed tumor in the surgical wounds of 27/84 mice (32%). None of these mice or nonsurgical mice developed tumor in the opposite or uninjured pelvic bone (P < 0.0001). When different numbers (10(5), 5 x...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930560311
更新日期:1994-07-01 00:00:00
abstract::Two synchronous primary lung carcinomas presenting bilaterally are rare. Their presentation, predisposing factors, and treatment are similar to those of single lung carcinomas. The authors present the first reported case known to them of three synchronous primary lung carcinomas involving both lungs. These tumors fulf...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930340408
更新日期:1987-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Gastric cancer recurrence after curative surgery remains high. Although no preoperative marker of gastric cancer progression after radical gastrectomy exists, recent studies suggest that C-reactive protein (CRP) is associated with cancer progression. Our study evaluated the significance of pre...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.22129
更新日期:2012-03-15 00:00:00
abstract::Giant cell tumor of bone is a challenging surgical problem due to its mostly aggressive growth with tendency to recur locally, to develop in rare instances pulmonary metastases without histologic evidence of malignant changes, and due to its potential to dedifferentiate into a frankly malignant tumor in a limited numb...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930570408
更新日期:1994-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Stage II colon cancer is primarily a surgical disease. Only a still not well-defined subset of patients may benefit from postoperative adjuvant chemotherapy. The relationship between adjuvant chemotherapy and survival after relapse is furthermore still not definitely explored in this group of ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25798
更新日期:2019-12-11 00:00:00
abstract:PURPOSE:The aims of the study were to estimate the frequency of epiphora and to identify factors associated with epiphora after orbital-sparing maxillectomy via modified Weber-Ferguson incision with lower blepharoplasty (OSOSM-MWFILB). METHODS:We performed a retrospective cohort study enrolling a sample derived from t...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.26408
更新日期:2021-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Re-excision surgery is undertaken to obtain clear margins after breast-conserving surgery (BCS) for localized breast cancer. This study examines patient and tumor characteristics related to re-excision surgery in the universal-access Military Health System (MHS). METHODS:Retrospective analysi...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25788
更新日期:2019-11-29 00:00:00
abstract:BACKGROUND:Recurrent pleomorphic adenoma (PA) of the parotid gland is a challenging surgical issue with controversy regarding management and long term outcome. METHODS:All patients who were operated for recurrent PA of the parotid gland between the years 1991 and 2013 were reviewed. Patient demographics, clinicopathol...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24392
更新日期:2016-11-01 00:00:00
abstract::DNA nuclear content and PCNA index (proportion of PCNA reactive cells) have been studied by flow cytometry in eight pancreatic lesions producing hyperinsulinemic hypoglycemia to assess DNA ploidy and tumoral growth fraction. Adult nesidioblastosis had a diploid DNA index, two adenomas were near diploid, and four of th...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930590105
更新日期:1995-05-01 00:00:00
abstract::Patients with advanced glottic cancer, in whom there is extensive subglottic disease and/or low cervical lymph node metastasis, have a high incidence of recurrence in and about the tracheal stoma. Stoma recurrences can be prevented by immediate postoperative megavoltage radiotherapy when the stoma is included in the i...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930070303
更新日期:1975-01-01 00:00:00
abstract::The sentinel node (SN) is defined as the first draining node from the primary lesion and it has proven to be a good indicator of the metastatic status of regional lymph nodes in solid tumors. In the past 5 years, the validity of SN concept for gastric cancer has been demonstrated by a number of single institutional st...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.20220
更新日期:2005-06-01 00:00:00
abstract::A 29-year-old female was diagnosed with a symptomatic, extra-abdominal desmoid tumor during the first trimester of pregnancy. Computerized tomography (CT) and transabdominal ultrasound (US) noted a mass within the left rectus sheath measuring up to 15 cm in greatest diameter, with mild compression of the uterus. Preop...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20189
更新日期:2005-02-01 00:00:00
abstract::Retroperitoneal sarcomas (RPS) frequently involve major vessels, which either originate from them or secondarily encase or invade them. In this field, major vascular resections result in increased morbidity. However, survival does not seem to be affected by the need for vascular resection or by this higher morbidity. ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.24920
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The therapeutic role of systematic lymph node dissection (LND) remains unclear in advanced epithelial ovarian cancer (EOC), especially during interval debulking surgery (IDS) performed after neoadjuvant chemotherapy (NAC). We analyzed the therapeutic and prognostic roles of systematic LND in ad...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24669
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:Little data regarding the selection of nonsurgical therapies for localized intrahepatic cholangiocarcinoma (ICC) are available. METHODS:A cohort of nonsurgically managed patients with American Joint Commission on Cancer clinical stage I/II ICC in the United States from 2004 to 2013 were identified in the Na...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25736
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Destructive metastatic lesions about the acetabulum result in pain and functional limitations. We assessed whether periacetabular reconstruction (PAR) improves quality of life by examining outcome measures of pain, function, and mobility. METHODS:Thirty-seven patients with a mean follow-up of 23....
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21440
更新日期:2010-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:We performed a retrospective analysis to assess the influence of different prognostic factors, including the International Prognostic Index (IPI), that can predict the outcome in patients with primary large bowel lymphoma (Stage IE) treated with combined therapy (surgery followed by chemothera...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.10103
更新日期:2002-06-01 00:00:00
abstract::Thirty-eight cases of advanced upper gastrointestinal cancer were assessed for their immune status prior to any form of therapy. Cell-mediated immunity, as tested by absolute lymphocyte count, T-cell count and delayed cutaneous hypersensitivity reactions to purified protein derivative and phytohemagglutinin showed sev...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930290113
更新日期:1985-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The study of pathology and prognosis for patients with ovarian tumors of low malignant potential (LMP) has been well documented. The treatment, particularly the secondary surgery, for recurrent disease is less documented. This study was conducted to investigate the role of secondary surgical c...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20280
更新日期:2005-07-01 00:00:00
abstract::Most solid tumors have now been reported to contain stem cell-like cells called cancer stem cells (CSCs). These cells are endowed with high tumorigenic capacity and may be the cells that drive tumor formation, maintain tumor homeostasis, and mediate tumor metastasis. Since these self-renewing cancer cells may be the s...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.21806
更新日期:2011-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Two staged tissue expander-implant with acellular dermal matrix (TE/I + ADM) and deep inferior epigastric perforator (DIEP) flap are the most common implant and autologous methods of reconstruction in the U.S. Implant-based techniques are disproportionally more popular, partially due to its pr...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
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更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:Immunoreactivity for p53 tumor suppressor gene product is commonly found in human malignancies and some premalignant lesions, but its role in cancer development and its value as a marker of tumor biologic behavior is still unclear. OBJECTIVES:This study was undertaken to assess p53 immunoexpression in esoph...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9098(199705)65:1<3::aid-jso2>3.
更新日期:1997-05-01 00:00:00