Abstract:
:DNA nuclear content and PCNA index (proportion of PCNA reactive cells) have been studied by flow cytometry in eight pancreatic lesions producing hyperinsulinemic hypoglycemia to assess DNA ploidy and tumoral growth fraction. Adult nesidioblastosis had a diploid DNA index, two adenomas were near diploid, and four of the adenomas and the carcinoma were aneuploid. The median value of PCNA index (6.056% +/- 6.76) was significantly correlated (P < 0.05) with the mean tumor diameter (2.43 cm +/- 1.96). Tumors with a PCNA index < 6.056% showed a diameter less than the mean tumoral diameter and a benign clinical course. Tumors with PCNA index > 6.056% generally displayed a diameter bigger than the mean tumoral diameter, being associated with lymph node metastases in one case. The authors conclude that nuclear DNA and PCNA index cytometric studies are useful parameters to assess the biological behavior of pancreatic lesions producing hyperinsulinemic hypoglycemia.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Losada J,Sarria R,Fernandez Val JF,Lopez Ariztegui MAdoi
10.1002/jso.2930590105subject
Has Abstractpub_date
1995-05-01 00:00:00pages
14-7issue
1eissn
0022-4790issn
1096-9098journal_volume
59pub_type
杂志文章abstract:BACKGROUND:Pathological staging and regression grading may affect the clinical outcome in rectal carcinoma patients treated with neoadjuvant chemoradiation (NACRT). Oncocytic change (OC) has also been described in the residual tumor. This study assesses the correlation of degree of pathological response and OC with cli...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.22073
更新日期:2012-02-01 00:00:00
abstract::A 57-year-old man first noted tender subcutaneous nodules on his extremities and abdomen. Six months later symptoms of insulin hypersecretion became evident and hyperinsulinemia was documented. An exploratory laparotomy revealed an islet cell tumor measuring 12 cm in diameter extending anteriorly from head of the panc...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930160402
更新日期:1981-01-01 00:00:00
abstract::Prevention of cancer is now divided into primary and secondary prevention. Primary prevention is that set of interventions that keeps a cancerous process from ever developing and includes health counseling and education, environmental controls. and product safety as examples. Secondary prevention is that set of interv...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930180302
更新日期:1981-01-01 00:00:00
abstract:BACKGROUND:Extrapleural pneumonectomy for malignant pleural mesothelioma is considered an aggressive procedure, but symptomatic and quality of life changes are unknown. METHODS:Between 1997 and 2004, 16 consecutive patients underwent extrapleural pneumonectomy for mesothelioma followed by chemo-radiotherapy. Tumor-rel...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21261
更新日期:2009-09-01 00:00:00
abstract::A totally implantable venous access system is described which greatly improved the ability to gain long-term venous access in selected patients. The external jugular approach has been demonstrated to be a safe and simple technique. The only major problem associated with the implantable venous access system was the dev...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930370413
更新日期:1988-04-01 00:00:00
abstract::A case of leiomyosarcoma arising from the dartos muscle of the scrotum is described. Review of the literature reveals only eight other cases, and aspects of management of these and our case are discussed. ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.2930340309
更新日期:1987-03-01 00:00:00
abstract::The circumferential resection of the trachea with end-to-end anastomosis is a well-established clinical procedure. Still, some problems remain to be solved, such as the choice of optimal suture material. Dogs are primarily used for experimental work in this field, but are difficult to obtain. This operation was perfor...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930370114
更新日期:1988-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:There is paucity of studies on the predictors of bladder cancer (BC) management costs. We aimed to determine predictors of costs associated with radical cystectomy (RC) for BC. METHODS:We conducted a retrospective analysis in a cohort of 2,759 patients who underwent RC for BC between 2000 and...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24132
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:To describe the use of the mastoid skull post of a surgical image guidance system for image guided surgery and intraoperative navigation of the nasopharynx. This adaptation overcomes the limitations of a headset frame or head clamp and can be applied to open and closed surgery of the nasal cav...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21005
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The single-arm ROSiA study evaluated frontline bevacizumab for advanced ovarian cancer. We explored how discordant surgically and radiologically assessed postoperative residual disease affects outcomes. METHODS:After debulking surgery, 1021 patients received 4 to 8 cycles of carboplatin-pacli...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25647
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Peritoneal papillary serous carcinoma (PPSC) is histologically and clinically similar to stage III-IV ovarian papillary serous carcinoma (OPSC). The purpose of this study was to investigate the clinical findings, treatment, and outcome of PPSC patients compared with stage III-IV OPSC patients....
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9098(199807)68:3<173::aid-jso8>
更新日期:1998-07-01 00:00:00
abstract:INTRODUCTION:Many surgeons use the "10% rule" to define whether a lymph node is a sentinel node (SLN) when staging malignant melanoma. However, this increases the number of SLN removed and the time and cost of the procedure. We examined the impact of raising this threshold on the accuracy of the procedure. METHODS:We ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20729
更新日期:2007-06-15 00:00:00
abstract:OBJECTIVES:To identify the prognostic implications of human papillomavirus (HPV)-related cell cycle marker profiles in patients who have received a transoral lateral oropharyngectomy (TLO) as a primary treatment for tonsillar squamous cell carcinoma (TSCC). PATIENTS AND METHODS:Immunohistochemical profiles of HPV-rela...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23672
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:It has been estimated that approximately 5% of middle and low rectal adenocarcinomas are amenable to local therapy. However, these treatment modalities are limited by their failure to identify and treat regional nodal metastases. METHODS:This study was undertaken to evaluate the role of tumor...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9098(199802)67:2<99::aid-jso5>3
更新日期:1998-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The median of pO2 values in tumor measured by Eppendorf "Histograph" with a needle-type electrode has been used as a prognostic indicator in cancer patients. However, it is not established that a pretreatment measured pO2 value can be used as a universal predictor of local control probability,...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9098(199709)66:1<30::aid-jso7>3
更新日期:1997-09-01 00:00:00
abstract::Depending on the local extension of primary non-small cell lung cancer (NSCLC) and invaded T4 structure(s), 49 patients underwent complete (CR, n = 14) or palliative (PR, n = 13) resection of exploratory thoracotomy (ET, n = 22) between January 1982 and June 1988. Thoracic radiotherapy (TR) was given to all patients r...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930470402
更新日期:1991-08-01 00:00:00
abstract::With the rapid uptake of the robotic approach in gynecologic surgery, a thorough understanding of the technology, including its uses and limitations, is critical to maximize patient outcomes and safety. This review discusses the role of training modalities and development of curricula for robotic surgery. Furthermore,...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.24006
更新日期:2015-12-01 00:00:00
abstract::In patients with stage I Clark's level III and IV malignant melanoma (MM), recurrence rates of 30-60% can be expected after resection of the primary lesion. If metastatic disease could be detected early and treated in such patients, survival might be prolonged. Ninety patients (37 males and 53 females) with newly diag...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930350304
更新日期:1987-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Variants of CD44 have been proposed to be important in promoting tumor progression and metastasis. We attempted to determine the expression of CD44v6 product in advanced gastric cancer and to evaluate its prognostic value. METHODS:The expression of CD44v6 was analyzed immunohistochemically in...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.10082
更新日期:2002-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:We performed a retrospective analysis to assess the influence of different prognostic factors, including the International Prognostic Index (IPI), that can predict the outcome in patients with primary large bowel lymphoma (Stage IE) treated with combined therapy (surgery followed by chemothera...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.10103
更新日期:2002-06-01 00:00:00
abstract:BACKGROUND:Leiomyosarcoma of the inferior vena cava (IVC) is a rare tumor which presents a unique surgical challenge. We present a series of six cases of leiomyosarcoma resection performed with IVC reconstruction. METHODS:Retrospective chart review was performed for patients undergoing initial operative resection of p...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.23798
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Hepatocellular carcinoma (HCC) is one of the most malignant cancers in the world. The effect of preoperative transarterial chemoembolization (TACE) for resectable HCC is still controversial and cost-associated treatments are unknown. METHODS:We retrospectively compared clinical outcomes and resource utiliza...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21248
更新日期:2009-05-01 00:00:00
abstract::A specific red cell adhesion test was done in 243 patients with carcinoma of the cervix uteri and showed the presence of isoantigens in only 27.16% of the patients with infiltrating squamous cell carcinoma. There was a gradual loss of isoantigens during the development of carcinoma. The test can be usefully employed i...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930160111
更新日期:1981-01-01 00:00:00
abstract:BACKGROUND:Open extended cholecystectomy (O-EC) has long been the recommended treatment for resectable gallbladder cancer (GBC), while the minimally-invasive approach for EC (MIS-EC) remains controversial. Our aim was to analyze overall survival of GBC patients treated with MIS-EC vs O-EC at the national level. METHOD...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.26062
更新日期:2020-06-12 00:00:00
abstract::The records of 111 consecutive cases of carcinoma of the breast were reviewed and yielded 66 patients who had undergone liver scanning and determination of the serum alkaline phosphatase (alk p'tase), lactic dehydrogenase (LDH), and serum glutamic oxaloacetic transaminase (SGOT). Four of the 66 patients (6.1%) had a f...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930130313
更新日期:1980-01-01 00:00:00
abstract::Twenty-six patients with esophageal carcinoma at stage pT4 underwent esophagectomy with lymph node dissection leaving part of the tumor in adjacent organs. Several plastic catheters were fixed to the tumor bed and led to the outside of the thorax for postoperative brachytherapy. Using these catheters, the patients und...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/(SICI)1096-9098(199607)62:3<214::AID-JSO12
更新日期:1996-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Desmoplastic melanoma (DM) is a rare variant of cutaneous melanoma. Our goal was to study the surgical management of DM, identify prognostic factors, and impact of treatment options. METHODS:Patients with DM (n = 1,735) were identified from the Surveillance, Epidemiology, and End Results data...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21778
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:Skip metastasis to mediastinal lymph nodes is a well-known phenomenon in non-small cell lung cancer (NSCLC). Little is reported in the literature about its clinical importance. It is still under discussion whether any prognostic differences exist between resected NSCLC with either skip metastases or continuo...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.10219
更新日期:2003-04-01 00:00:00
abstract::Correlations between levels of tissue polypeptide antigen (TPA) in serum and histologic stage or progression of cancer were studied in 94 patients with gastric cancer. Levels of TPA in serum from patients with cancerous invasion into the vein of the stomach wall (v-invasion) were elevated in parallel to the progressio...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930410214
更新日期:1989-06-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Only a few surgeons with much experience of laparoscopic surgery perform laparoscopy-assisted total gastrectomy (LATG), because of its technical difficulty and concern about subsequent complications. The aim of this study was to evaluate the technical feasibility and safety of LATG as compared ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21345
更新日期:2009-10-01 00:00:00