Abstract:
BACKGROUND:Open extended cholecystectomy (O-EC) has long been the recommended treatment for resectable gallbladder cancer (GBC), while the minimally-invasive approach for EC (MIS-EC) remains controversial. Our aim was to analyze overall survival of GBC patients treated with MIS-EC vs O-EC at the national level. METHODS:A retrospective review of the National Cancer Database of patients with resectable GBC (2010-2016) and treated with either MIS-EC or O-EC was performed. Overall survival (OS) was compared by the surgical approach. RESULTS:A total of 680 patients were identified, of whom 235 (34.6%) underwent MIS-EC. There were no differences in the rates of positive margins between MIS-EC and O-EC (14% vs 19%, respectively; P = .278), and in the mean lymph node yield (6.54 vs 6.66, respectively; P = .914). The median survival following MIS-EC was significantly higher than that of O-EC (39 vs 26 months; P = .048). After stratification by pathological stage and after adjustment, there was no significant difference in OS between the groups (HR = 0.9, 95% CI, 0.6-1.5). CONCLUSION:In this large national cohort, MIS-EC oncologic outcomes were noninferior to the O-EC. Proficiency with MIS techniques, proper patient selection, and referral to specialized centers may allow a greater benefit from this treatment modality.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
AlMasri S,Nassour I,Tohme S,Adam MA,Hoehn RS,Bartlett DL,Lee KK,Zureikat AH,Paniccia Adoi
10.1002/jso.26062subject
Has Abstractpub_date
2020-06-12 00:00:00eissn
0022-4790issn
1096-9098pub_type
杂志文章abstract::Fibrosarcoma is a rare primary malignant tumor of the mediastinum. Three cases are presented with different presenting symptoms and clinical manifestations. Thoracotomy with biopsy of the mass is the only method for arriving at a definitive histologic diagnosis. ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930120103
更新日期:1979-01-01 00:00:00
abstract::Radioimmunoassay for serum carcinoembryonic antigen (CEA) was performed in 49 colonic cancer patients. The test results were positive in 42 patients (85.7%) in whom tumor was present at the time of assay. Preoperatively, CEA level suggested the extent and the prognosis of the disease. Strongly positive CEA test result...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930120206
更新日期:1979-01-01 00:00:00
abstract:PURPOSE:The aims of the study were to estimate the frequency of epiphora and to identify factors associated with epiphora after orbital-sparing maxillectomy via modified Weber-Ferguson incision with lower blepharoplasty (OSOSM-MWFILB). METHODS:We performed a retrospective cohort study enrolling a sample derived from t...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.26408
更新日期:2021-02-01 00:00:00
abstract::The realm of cancer chemotherapy is complex and often conflicting. The massive use of cytotoxic agents during the past 25 years has now reached a point where major decisions have to be made. The respective roles of regional techniques, systemic therapy for metastatic disease and adjuvant cytotoxic chemotherapy, all ne...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930300411
更新日期:1985-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Recent studies have disclosed the presence of somatic mutations in the epidermal growth factor receptor (EGFR) gene in non-small cell lung cancers (NSCLC), and susceptibility to the EGFR tyrosine kinase inhibitor (gefitinib) was determined by the presence of mutations in the kinase domain of t...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20426
更新日期:2006-01-01 00:00:00
abstract::A review of our 247 patients with adenocarcinoma of the lung revealed the overall five year survival rate to be only 0.81%. Lung resection offers the chance of cure if the lesion is peripherally located and without lymph node involvement. Direct chest wall invasion by tumor is not contraindication to surgery. Radiatio...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930070306
更新日期:1975-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Microsatellite instability (MSI) in gastric cancer (GC) is associated with older age. We present the clinicopathological results of younger and older patients with MSI GC. METHODS:We analyzed 472 patients with GC. MSI analysis was done on fresh frozen tissue using five quasimonomorphic mononu...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24513
更新日期:2017-03-01 00:00:00
abstract::Reconstructive procedures following chest wall resection pose a special surgical challenge. With modern surgical technique, a wide range of reconstructive options are at the surgeon's disposal and, hence it is imperative that the appropriate procedure be selected in a given patient. A total of 64 patients underwent re...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930550311
更新日期:1994-03-01 00:00:00
abstract::For 38 consecutive patients presenting with breast masses we compared accuracy of diagnosis, before biopsy, of the techniques of clinical examination, bilateral xeromammography, and aspiration cytology with a 10-cc syringe and a 22-gauge needle. Of the 38 patients, nine had carcinoma and 29 had benign breast disease. ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930120409
更新日期:1979-12-01 00:00:00
abstract:INTRODUCTION:Irreversible electroporation (IRE) has shown promise for ablation of lesions in proximity to vital structures in the preclinical setting. This study aims to evaluate the safety and efficacy of IRE for hepatic tumors in the clinical setting. METHODS:An IRB approved prospective registry of patients undergoi...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23280
更新日期:2013-04-01 00:00:00
abstract::Diffuse large cell lymphoma is frequently localized at the time of presentation, but the aggressive natural history of the disease in most patients has suggested that extensive and intensive radiation and/or chemotherapy is necessary to control this disease. We describe a patient who has remained free of disease for 2...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930210116
更新日期:1982-09-01 00:00:00
abstract::In 1976 Stewart et al. (Annals of the New York Academy of Sciences 277:436-466) reported the effectiveness of adjuvant specific active immunotherapy of lung carcinoma in improving the postoperative survival of stage I lung carcinoma patients in a phase II study using lung carcinoma-associated antigen (TAA) and complet...
journal_title:Journal of surgical oncology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/jso.2930460104
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Small lung adenocarcinomas are detected more frequently than in the past. However, the clinicopathologic characteristics and prognostic significance of EGFR/p53 mutations in these tumors remains unclear. METHODS:We evaluated the correlation of EGFR/p53 mutations with clinicopathologic charact...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23628
更新日期:2014-08-01 00:00:00
abstract::Infertility because of testicular damage is a distressing problem for survivors of cancer chemotherapy. We have previously described a cytoprotective effect of temporary testicular circulatory isolation (TCI) during doxorubicin administration in the rat. In this report we define the relationship between duration of TC...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930390410
更新日期:1988-12-01 00:00:00
abstract::Until recent years, the prognosis for breast cancer in pregnancy and lactation was regarded as grave. The current new data suggest that pregnant women with early breast carcinoma may be treated in the same way as nonpregnant women without affecting pregnancy. However, women with breast cancer in their first trimester ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930210310
更新日期:1982-11-01 00:00:00
abstract::Fluorescence-guided surgery can enhance the surgeon's ability to achieve a complete oncologic resection. There are a number of tumor-specific probes being developed with many preclinical mouse models to evaluate their efficacy. The current review discusses the different preclinical mouse models in the setting of probe...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.25150
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND AND METHOD:The association between margin width and ipsilateral breast tumour recurrence (IBTR, defined as invasive recurrence) was investigated in a population-based nationwide cohort of 11,900 patients undergoing breast-conserving therapy for invasive cancer. RESULTS:The median follow-up was 4.9 years. Th...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24224
更新日期:2016-05-01 00:00:00
abstract::Distribution of Leu-7+ cells in cancer tissues and regional lymph nodes was immunohistochemically examined to estimate the role of NK cells in colorectal cancer patients. Leu-7+ cells were rarely observed both in the primary and distant metastatic lesions, but the number of these cells was large in the germinal center...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930450406
更新日期:1990-12-01 00:00:00
abstract::Leiomyosarcoma of the colon is a rare neoplasm. It is widely known that primary malignant lesions may present either simultaneously (synchronous tumor) or at different times (metachronous tumor). The incidence of metachronous colonic mucosal carcinoma is generally considered to range from 3 to 5%. Metachronous leiomyo...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930320403
更新日期:1986-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Transcription factor Snail1 is a key inducer of epithelial-mesenchymal transition (EMT), a biological process implicated in the cancer progression and metastasis. The aim of the study was to investigate Snail1 expression in DCIS found on breast biopsy and assess its predictive value for the fi...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24708
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Curative hepatic resection (CHR) was a modality that provides possibility of long-term survival for hepatocellular carcinoma (HCC). So far, prognostic factors of male patients with HCC after CHR remain unclear. Purposes of the present study were to identify these factors and to compare them wi...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20678
更新日期:2007-03-15 00:00:00
abstract:INTRODUCTION:Mucinous adenocarcinoma is a subtype of colonic adenocarcinoma associated with worse survival compared to nonmucinous adenocarcinoma. Prior studies on the effect of chemotherapy on survival in mucinous adenocarcinoma have shown mixed results. The aim of this study is to evaluate the effect of chemotherapy ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25705
更新日期:2019-12-01 00:00:00
abstract::A patient-specific 3-dimensional printed model (3DPM) of a woman with breast cancer was created. Mastectomy was favored as BCS would necessitate significant breast size alteration due to the extent of disease. After review of the 3D printed model, the patient and surgeon agreed on breast-conserving surgery. Use of pat...
journal_title:Journal of surgical oncology
pub_type:
doi:10.1002/jso.25680
更新日期:2019-11-01 00:00:00
abstract::38 specimens of benign breast tissue from young women and 92 primary breast carcinomas were evaluated for tritiated thymidine ([3H]TdR) labeling index (TLI) by in vitro pulse labeling. The TLI on nonneoplastic, terminal breast ducts was significantly higher during the latter half than during the first half of the mens...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930080212
更新日期:1976-01-01 00:00:00
abstract:PURPOSE:To investigate the significance of palliative gastrectomy for different types of metastatic gastric cancer patients displaying peritoneal dissemination, hepatic metastasis, distant lymph node metastasis occurring locally during late-stage disease, and multi-organ metastases. METHODS:We performed a retrospectiv...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23158
更新日期:2012-12-01 00:00:00
abstract::Leiomyoma of the rectum and anal canal is an unusual clinical entity. Generally, it does not produce any clinical signs and in most cases it is discovered incidentally in the course of routine rectal examination. The clinical presentation, diagnosis, and surgical treatment are described in two presented cases of anal ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930330210
更新日期:1986-10-01 00:00:00
abstract::An esophagogastric anastomotic leak, especially in the mediastinum or the chest, is a life-threatening complication of surgery for cancer of the esophagus. Of 617 patients who underwent esophageal resection and esophagogastric anastomosis between January 1980 and December 1989, 39 (6.32%) had anastomotic leakage; of t...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930490307
更新日期:1992-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Blue nevi are benign pigmented dermal lesions that can mimic cutaneous melanoma in appearance. Cellular components may infiltrate subcutaneous tissue. We present a complex case of cellular blue nevus (CBN) to demonstrate the ambiguous clinical appearance of these lesions and to provide an appr...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/1096-9098(200008)74:4<278::aid-jso7>3.0.co
更新日期:2000-08-01 00:00:00
abstract::The T N M staging system created by a surgeon in the 1950s continues to be a major benchmark for assessing long-term outcomes in adult solid tumors. Although several major changes have occurred in this anatomical staging system, the tenets of TNM staging remain constant. Recently molecular markers and biologic modifie...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.23704
更新日期:2014-10-01 00:00:00
abstract::Palliative care (PC) seeks to improve the quality of life for patients facing serious illness. Several oncology organizations have guidelines about PC, reflecting the need to integrate PC into standard oncology care. Many surgical patients do not receive PC despite the need for these services and established surgical ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.25449
更新日期:2019-07-01 00:00:00