Abstract:
:Six hundred sixty-eight patients with tumours of the larynx were treated by radiotherapy. The patients had stage T1 N0 M0 to T4 N3 M0 disease. Patients with T1 N0 M0 disease (273) had an excellent long-term survival (90%) as did those with T2 N0 M0 disease (142), whose 5-year survival was 70%. Patients with more advanced disease but no nodal spread did not respond as readily to radiotherapy; the 5-year survival was 40%. All patients were treated using a parallel pair set-up 6 X 6 cm lateral neck fields. A more aggressive radiotherapy regime to a larger tissue volume to include microscopic spread to lymph nodes may improve survival of locally advanced disease.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Robertson AG,Boyle P,Deuchars F,Robertson Cdoi
10.1002/jso.2930350402subject
Has Abstractpub_date
1987-08-01 00:00:00pages
217-22issue
4eissn
0022-4790issn
1096-9098journal_volume
35pub_type
杂志文章abstract:BACKGROUND AND OBJECTIVES:The aim of this study was to evaluate the role of indocyanine green (ICG) fluorescence imaging (FI) for the ex vivo detection of metastatic lymph nodes (LNs) in advanced stage ovarian cancer (AOC). METHODS:Paraffin-embedded LNs from patients included in a previous ICG-FI study (Protocol NCT01...
journal_title:Journal of surgical oncology
pub_type: 临床试验,杂志文章
doi:10.1002/jso.25263
更新日期:2018-12-01 00:00:00
abstract::Due to the close spatial relationship of head and neck and skull base tumors to numerous normal anatomical structures, conventional photon radiation therapy can be associated with significant acute and long-term treatment-related toxicities. Superior dose localization properties of proton radiation therapy allow small...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.21013
更新日期:2008-06-15 00:00:00
abstract:OBJECTIVES:Gasless transaxillary endoscopic thyroidectomy offers a distinct advantage over the conventional open operation because it leaves no visible neck scar. Indications have expanded with the development of new surgical techniques and instruments. However, because of the two-dimensional view and the nonflexible i...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.22106
更新日期:2012-06-01 00:00:00
abstract::Giant cell tumor of bone is a challenging surgical problem due to its mostly aggressive growth with tendency to recur locally, to develop in rare instances pulmonary metastases without histologic evidence of malignant changes, and due to its potential to dedifferentiate into a frankly malignant tumor in a limited numb...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930570408
更新日期:1994-12-01 00:00:00
abstract::A retrospective analysis of 328 cases of Hodgkin's Disease (HD) subjected to a staging laparotomy at the Tata Memorial Hospital, Bombay, India, from 1974 to 1986 was undertaken to assess its relevance to our setup. Eighty percent of the patients were from clinical stages (CS) I and II, 38% with lymphocyte predominance...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930490110
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND AND METHOD:The association between margin width and ipsilateral breast tumour recurrence (IBTR, defined as invasive recurrence) was investigated in a population-based nationwide cohort of 11,900 patients undergoing breast-conserving therapy for invasive cancer. RESULTS:The median follow-up was 4.9 years. Th...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24224
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Arterial resection (AR) has traditionally been considered as a contraindication to pancreatic resection for locally advanced pancreatic adenocarcinoma. The objective was to evaluate if pancreatic resection with AR was worthwhile. METHODS:Between January 1990 and December 2008 the records of 2...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21769
更新日期:2011-01-01 00:00:00
abstract::Until recent years, the prognosis for breast cancer in pregnancy and lactation was regarded as grave. The current new data suggest that pregnant women with early breast carcinoma may be treated in the same way as nonpregnant women without affecting pregnancy. However, women with breast cancer in their first trimester ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930210310
更新日期:1982-11-01 00:00:00
abstract::Pedicled and free composite flaps derived from the thoracodorsal artery system, including the latissimus dorsi-rib (LD-R) and the serratus anterior-rib (SA-R) osteo-muscular or osteo-myocutaneous flaps, are potential options to address head and neck, thorax, upper and lower extremity bone, and soft tissue defects' rec...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25579
更新日期:2019-09-01 00:00:00
abstract::Follicular thyroid carcinoma, initially presenting as spinal cord compression due to metastatic lesions, is a less reported event. We present two cases of well-differentiated thyroid carcinoma that led to spinal cord compression. A thorough search of the literature revealed only five similar cases. We summarize the cl...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/(sici)1096-9098(199803)67:3<186::aid-jso8>
更新日期:1998-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Long noncoding RNAs (lncRNAs) play key roles in carcinoma metastasis. We aimed to investigate lncRNA LINC01133 in oral squamous cell carcinoma (OSCC) metastasis. METHODS:The RNA levels of LINC01133 and growth and differentiation factor 15 (GDF15) in tissue samples from OSCC patients, and OSCC...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25278
更新日期:2018-12-01 00:00:00
abstract::Brachytherapy, the direct application of a radioactive isotope into the tumor bed, delivers a high dose to the tumor as compared to the surrounding normal tissue. Interstitial brachytherapy, the placement of the isotope into a tumor bed where no lumen exists, has been described but is utilized infrequently in clinical...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/(sici)1096-9098(199801)67:1<60::aid-jso13>
更新日期:1998-01-01 00:00:00
abstract::Microsurgical techniques have revolutionized pharyngolaryngeal reconstruction. Free flap reconstruction with the free jejunal flap enables one stage reconstruction with minimal morbidity and mortality. This review will examine indications, operative technique, postoperative management, and expected outcomes for the hy...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.20483
更新日期:2006-11-01 00:00:00
abstract:OBJECTIVE:To determine whether serum prealbumin levels are associated with long-term survival after hepatectomy in patients with primary hepatocellular carcinoma(HCC). METHODS:A consecutive sample of 526 patients with HCC who underwent potentially curative hepatectomy from August 2007 to August 2010 was retrospectivel...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25378
更新日期:2019-05-01 00:00:00
abstract::Interleukin-2 and hyperthermia have been used individually to treat a variety of tumors in both experimental and human trials. Combined adoptive immunotherapy and hyperthermia is an exciting new line of investigation. Previous work in our laboratory has shown that combined local hyperthermia and rIL-2 therapy can sign...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930530310
更新日期:1993-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:MicroRNAs (miRNAs) are small, noncoding RNAs that are involved in carcinogenesis through postranscriptional gene regulatory activity. Few studies have focused on the detection of miR-21 in serum rather than in tissue. The current study aimed to measure serum miR-21 expression levels and to eva...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23415
更新日期:2013-11-01 00:00:00
abstract::A patient with metastasizing glucagonoma producing multiple molecular forms of glucagon is reported. The patient responded to symptomatic treatment with a somatostatin analogue (SMS 201-995). Glucagonoma tumour cells were studied in two tissue culture systems: intraocular transplants of immunosuppressed rats and long-...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930440313
更新日期:1990-07-01 00:00:00
abstract::The incidence of anastomotic leakage after esophagectomy for cancer and reconstruction with the stomach was analyzed with respect to the presence of coexistent atrophic chronic gastritis (ACG). Of a total of 28 operated esophageal cancer patients with ACG, 6 patients developed an anastomotic leak at the cervical esoph...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930510107
更新日期:1992-09-01 00:00:00
abstract::Most solid tumors have now been reported to contain stem cell-like cells called cancer stem cells (CSCs). These cells are endowed with high tumorigenic capacity and may be the cells that drive tumor formation, maintain tumor homeostasis, and mediate tumor metastasis. Since these self-renewing cancer cells may be the s...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.21806
更新日期:2011-05-01 00:00:00
abstract:BACKGROUND:Leiomyosarcoma of the inferior vena cava (IVC) is a rare tumor which presents a unique surgical challenge. We present a series of six cases of leiomyosarcoma resection performed with IVC reconstruction. METHODS:Retrospective chart review was performed for patients undergoing initial operative resection of p...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.23798
更新日期:2015-03-01 00:00:00
abstract::Oncoplastic surgery combines plastic surgical techniques with sound surgical oncologic principles. The goal is to completely excise the cancer, with wide surgical margins while maintaining or improving cosmesis. For large, poorly defined, or unfavorably situated tumors, standard lumpectomies may lead to unacceptable c...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.23641
更新日期:2014-07-01 00:00:00
abstract::The data on 62 patients with germinal testicular tumors seen at King Faisal Specialist Hospital and Research Centre between January 1977 and June 1983 were analyzed to determine the epidemiologic and clinical characteristics of the disease in Saudi Arabia. Fifty-seven patients were Saudis. The geographic distribution ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930350109
更新日期:1987-05-01 00:00:00
abstract:OBJECTIVES:To identify the prognostic implications of human papillomavirus (HPV)-related cell cycle marker profiles in patients who have received a transoral lateral oropharyngectomy (TLO) as a primary treatment for tonsillar squamous cell carcinoma (TSCC). PATIENTS AND METHODS:Immunohistochemical profiles of HPV-rela...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23672
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The aim of this study was to evaluate the expression and prognostic roles of human ether à go-go related gene (hERG1) potassium channels in resected esophageal squamous cell carcinoma. METHODS:Expression of hERG1 protein and mRNA was detected by immunohistochemistry and reverse transcription ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20891
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Lymph node involvement is common in thyroid cancer, but the system of staging does not consider the histological features of lymph node metastases. We conducted a meta-analysis to investigate the prognostic role of extranodal extension (ENE) in thyroid cancer patients. METHODS:We ran PubMed a...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,meta分析,评审
doi:10.1002/jso.24070
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:This study aims to investigate the surgical outcomes observed in robotic transperitoneal aortic lymphadenectomy (AL) in gynecological cancer patients. METHODS:Retrospective data were collected and analyzed on 71 patients undergoing robotic surgical procedures for gynecological cancers, includi...
journal_title:Journal of surgical oncology
pub_type: 临床试验,杂志文章
doi:10.1002/jso.25335
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Neoadjuvant protocols in the management of upper extremity sarcoma have improved local control rates but have been associated with high complication rates. We present a refinement of the Eilber protocol using judicious preoperative chemoradiation, limb salvage surgery, and flap coverage to ach...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20629
更新日期:2007-02-01 00:00:00
abstract::A case report is presented giving the first detailed description of a benign common duct stricture occurring in a patient receiving hepatic artery infusion of FUDR for metastatic colon cancer. It is postulated that the stricture results from a combination of drug toxicity, and hypoxemia of the duct, with the lesion oc...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930310113
更新日期:1986-01-01 00:00:00
abstract::Most surgical oncologists receive exposure to clinical studies in their fellowships; however they receive little if any practical knowledge as to how to become a clinical researcher. This article will provide a broad introduction to setting up a community based surgical oncology research program with emphasis on the p...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.21780
更新日期:2011-09-01 00:00:00
abstract::Thyroidectomy is a common surgical procedure. The results of some clinical trials suggest that routine drainage does not offer advantages, but the evidence is not strong either in favor of or against this intervention. The effect of routine drainage compared to no drainage in patients subject to thyroidectomy was meas...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,meta分析,评审
doi:10.1002/jso.20821
更新日期:2007-09-01 00:00:00