The relevance of a staging laparotomy for Hodgkin's disease in India.

Abstract:

:A retrospective analysis of 328 cases of Hodgkin's Disease (HD) subjected to a staging laparotomy at the Tata Memorial Hospital, Bombay, India, from 1974 to 1986 was undertaken to assess its relevance to our setup. Eighty percent of the patients were from clinical stages (CS) I and II, 38% with lymphocyte predominance (LP), and 41% with mixed cellularity (MC) histologies. Staging laparotomy was positive in 60% cases overall, including 50% from CS IA and IIA, 68% from CS IB and IIB, and 53% and 67%, respectively, from LP and MC histologies. Splenic involvement was seen in 54% cases. Operative complications were encountered in 2% of cases and deaths in two cases only. In view of the high propensity for abdominal spread, only selected CS IA and IIA cases would merit a staging laparotomy within which, nearly 50% cases with a negative yield could be offered radical segmental irradiation alone for cure. The majority of our patients would, however, require combination therapy.

journal_name

J Surg Oncol

authors

Dinshaw KA,Pande SC,Shrivastava SK,Gonsalves MA,Advani SH,Gopal R,Shrikhande SS,Desouza LJ,Jagannath P,Desai PB

doi

10.1002/jso.2930490110

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

39-44

issue

1

eissn

0022-4790

issn

1096-9098

journal_volume

49

pub_type

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