Abstract:
INTRODUCTION:The number of incidentally discovered adrenal lesions is increasing due to the widespread use of abdominal imaging. Although most incidentalomas are benign, larger suspicious lesions will require adrenalectomy. The aim of this study is to determine the risk of malignancy in patients undergoing surgery for adrenal incidentaloma; and to compare clinical outcomes in those with adrenocortical carcinoma (ACC) based on the mode of presentation. METHODS:A retrospective study of consecutive patients who underwent adrenalectomy between 1995 and 2008 was performed. Data were retrieved from a prospectively maintained adrenal tumor database. Those with adrenal incidentaloma were selected and histopathology reviewed. All patients with ACC (presenting with symptoms or incidentally) during the same time period were identified and clinical outcomes compared. RESULTS:Adrenalectomy was performed in 274 patients of whom 73 (27%) were characterized pre-operatively as incidentaloma. Benign, non-functioning adrenocortical adenoma was the most common histopathological finding (46 patients, 63%). There was a trend (P = 0.08) towards increased survival amongst the seven patients with ACC presenting incidentally compared to the nine patients with symptomatic ACC. CONCLUSIONS:Adrenal incidentalomas have a small but important risk of malignancy. ACC presenting as incidentaloma appear to have a more favorable prognosis than symptomatic or functioning ACC.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
O'Neill CJ,Spence A,Logan B,Suliburk JW,Soon PS,Learoyd DL,Sidhu SB,Sywak MSdoi
10.1002/jso.21553subject
Has Abstractpub_date
2010-10-01 00:00:00pages
450-3issue
5eissn
0022-4790issn
1096-9098journal_volume
102pub_type
杂志文章abstract::As patients with ovarian cancer are living longer, surgeons will be faced with the management of metastatic lesions amenable to resection more frequently. We present two patients with ovarian cancer metastatic to the breast who underwent resection for their metastases, but their outcomes differed significantly. After ...
journal_title:Journal of surgical oncology
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abstract:BACKGROUND AND OBJECTIVES:Little data is currently available on the usefulness of peak-standardized uptake value (P-SUV) by positron emission tomography-computed tomography (PET-CT) in gastric cancer. The purpose of the present study was to evaluate the value of PET-CT for the preoperative evaluation of patients with g...
journal_title:Journal of surgical oncology
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abstract::For 38 consecutive patients presenting with breast masses we compared accuracy of diagnosis, before biopsy, of the techniques of clinical examination, bilateral xeromammography, and aspiration cytology with a 10-cc syringe and a 22-gauge needle. Of the 38 patients, nine had carcinoma and 29 had benign breast disease. ...
journal_title:Journal of surgical oncology
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journal_title:Journal of surgical oncology
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abstract::Oncogenes, tumor suppressor genes, and growth factors are being explored as to their role in the initiation and progression of most neoplasms, but little information exists on the expression of oncoproteins or growth factors in adenocarcinoma of the duodenum or ampulla of Vater. This report covers expressions of p53, ...
journal_title:Journal of surgical oncology
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abstract::Biopsies from 61 women with breast cancer were assessed for various histological features. These results were statistically analyzed for associations of gross tumor size, patient age, stage of disease, tumor hormone receptor status, with accepted systems of nuclear and histological grading for differentiation. Tumors ...
journal_title:Journal of surgical oncology
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abstract::During the past 53 years, 105 patients with Wilms' Tumor have been treated at the Children's Hospital of Buffalo. Prospective and retrospective staging of these cases has allowed comparison with other reported series. All-stage survival improved from 37% with operation alone to 46% with operation and planned radiother...
journal_title:Journal of surgical oncology
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journal_title:Journal of surgical oncology
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journal_title:Journal of surgical oncology
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journal_title:Journal of surgical oncology
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journal_title:Journal of surgical oncology
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journal_title:Journal of surgical oncology
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更新日期:2009-11-01 00:00:00
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journal_title:Journal of surgical oncology
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journal_title:Journal of surgical oncology
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更新日期:2020-10-01 00:00:00
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journal_title:Journal of surgical oncology
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journal_title:Journal of surgical oncology
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更新日期:2015-04-01 00:00:00
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journal_title:Journal of surgical oncology
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doi:10.1002/jso.2930190411
更新日期:1982-04-01 00:00:00
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journal_title:Journal of surgical oncology
pub_type: 杂志文章
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更新日期:1989-04-01 00:00:00
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journal_title:Journal of surgical oncology
pub_type: 杂志文章
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journal_title:Journal of surgical oncology
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journal_title:Journal of surgical oncology
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journal_title:Journal of surgical oncology
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journal_title:Journal of surgical oncology
pub_type: 临床试验,杂志文章
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journal_title:Journal of surgical oncology
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更新日期:2006-12-01 00:00:00
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journal_title:Journal of surgical oncology
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更新日期:2008-02-01 00:00:00
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journal_title:Journal of surgical oncology
pub_type: 杂志文章
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更新日期:1998-08-01 00:00:00
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journal_title:Journal of surgical oncology
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journal_title:Journal of surgical oncology
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更新日期:2005-12-15 00:00:00
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journal_title:Journal of surgical oncology
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journal_title:Journal of surgical oncology
pub_type: 杂志文章
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更新日期:1994-11-01 00:00:00