Abstract:
:Among catecholamine synthesizing enzymes, phenylethanolamine-N-methyltransferase (PNMT) exists only in adrenal and extra-adrenal pheochromocytoma has been believed not to produce adrenaline. However, adrenaline production is clinically active in some extra-adrenal cases. To investigate this controversy, the localization of catecholamine synthesizing enzymes was studied by immunohistochemical staining in extra-adrenal and adrenal cases. The results showed that PNMT was expressed not only in many cases of adrenal pheochromocytoma, but also in extra-adrenal pheochromocytoma. It is suspected that little adrenaline production in extra-adrenal cases is attributable to a lack of a good environment for the activation of PNMT by a high concentration of glucocorticoids.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Funahashi H,Imai T,Tanaka Y,Tobinaga J,Wada M,Matsuyama T,Tsukamura K,Yamada F,Takagi H,Narita Tdoi
10.1002/jso.2930570312subject
Has Abstract,Author List Incompletepub_date
1994-11-01 00:00:00pages
196-200issue
3eissn
0022-4790issn
1096-9098journal_volume
57pub_type
杂志文章abstract:BACKGROUND AND OBJECTIVES:Pheochromocytoma (PHEO) and paraganglioma (PGL) are rare tumors. Aims of this study were to describe and to compare demographic, clinical, pathologic, and survival characteristics of malignant PHEO and PGL. METHODS:Patients were identified in SEER, 1988-2009. Analyses included chi-square, ANO...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23297
更新日期:2013-05-01 00:00:00
abstract::A specific red cell adhesion test was done in 243 patients with carcinoma of the cervix uteri and showed the presence of isoantigens in only 27.16% of the patients with infiltrating squamous cell carcinoma. There was a gradual loss of isoantigens during the development of carcinoma. The test can be usefully employed i...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930160111
更新日期:1981-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:ERCP prior to pancreaticoduodenectomy is unnecessary in select patients. When performed, it should be in conjunction with endoscopic ultrasound (EUS) to increase diagnostic sensitivity and allow for metal stent placement. The aim of this study was to determine differences in endoscopic practic...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24191
更新日期:2016-05-01 00:00:00
abstract::Xenografts of a human pancreatic carcinoma cell line, HPC-YS, which reacted with the monoclonal antibody (MAb) A7, were used to investigate the in vivo localization of radioiodinated MAb A7 after intraperitoneal injection. MAb A7 localized to the tumor 4 days and 8 days after injection with a tissue/blood ratio of 1.4...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930500309
更新日期:1992-07-01 00:00:00
abstract::Involvement of nose and maxilla by fibrosarcoma is extremely rare. Only a few cases of fibrosarcoma arising in this region are reported in the world literature. Two cases of fibrosarcoma are described, and the literature relating to this disease entity is briefly reviewed. Salient features helping in the diagnosis and...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930150109
更新日期:1980-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Neoadjuvant protocols in the management of upper extremity sarcoma have improved local control rates but have been associated with high complication rates. We present a refinement of the Eilber protocol using judicious preoperative chemoradiation, limb salvage surgery, and flap coverage to ach...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20629
更新日期:2007-02-01 00:00:00
abstract::This article reviews immediate and delayed breast reconstruction with prosthetic implants, and the effect of irradiation therapy. Despite widespread use of breast conserving surgery for early breast cancer, many breast cancer patients still undergo mastectomy. Some of these patients choose breast reconstruction. Over ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.20484
更新日期:2006-11-01 00:00:00
abstract::Forty-four consecutive cases of "early gastric cancer" were studied according to the macroscopic classification proposed by the Japanese Gastroenterological and Endoscopy Society and further analyzed in terms of growth patterns. The tumours were then classified into the small mucosal type, the superficially spreading ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930510211
更新日期:1992-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Prolonged air leaks (PAL) are the most frequent complication after lobectomy for non-small cell lung cancer, even in case of minimally invasive approaches. We developed a novel score to identify high-risk patients for PAL during minimally invasive lobectomy. METHODS:A dedicated database was c...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25289
更新日期:2018-12-01 00:00:00
abstract::The use of preoperative imaging has become routine for many reconstructive microsurgeons to help localize perforators for planning of microvascular free flaps. However, with advancements in imaging technology, perforator mapping represents only one potential benefit as virtual planning and medical modeling, and flap t...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.25194
更新日期:2018-10-01 00:00:00
abstract::High-quality data support multiple clinical benefits of integrating palliative care into routine oncology care. Though these data come largely from the medical oncology literature, data from surgical oncology populations support similar associations between palliative care integration and improved clinical outcomes, a...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.25454
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The genetic alterations involved in extrahepatic bile duct (EHBD) cancer are poorly understood. Our aim was to identify aberrations of the K-ras, p53, and APC genes in EHBD cancer. METHODS:We investigated aberrations of these genes in 52 EHBD cancers using polymerase chain reaction (PCR) sing...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9098(200003)73:3<158::aid-jso9>
更新日期:2000-03-01 00:00:00
abstract::The hanging liver maneuver is a useful technique to guide the transection of liver parenchyma by lifting a tape passed between the anterior surface of the inferior vena cava and the liver. Modified hanging liver maneuvers have been described in different types of liver resection. Surgical resection of hilar cholangioc...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24154
更新日期:2016-03-01 00:00:00
abstract::The aim of this study was to investigate the compound 4-nitro-1-cyclohexyl-3-ethoxy-2-oxo-3-pyrroline (NOPYE) and some related compounds for skin sensitization in guinea pigs, as the first step in a search for more effective skin sensitizers for immunotherapy of cutaneous tumors. In guinea pigs, NOPYE and NOPYE-L-alan...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930130209
更新日期:1980-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Certain tumor-related factors like thickness increases the risk of nodal metastasis and may affect survival in patients with oral tongue cancers. The objective of this study is to identify those tumor-related prognostic predictors that can potentially influence decision for adjuvant radiothera...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23583
更新日期:2014-06-01 00:00:00
abstract::Intra-abdominal visceral sarcomas are a rare group of mesenchymal tumors that require the use of distinct surgical principles and a multidisciplinary approach in order to optimize treatment. Surgery remains the only potentially curative treatment. Management and outcomes vary for the different sarcomas arising from vi...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23803
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:Heme oxygenase-1 (HO-1) correlates with aggressive tumor behavior and chemotherapy resistance in pancreatic cancer (PC). We evaluated the prognostic value of the basal transcription controlling germ line GTn repeat polymorphism (GTn) in the promoter region of the HO-1 gene in PC. PATIENTS AND METHODS:We det...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21926
更新日期:2011-09-01 00:00:00
abstract::In our previous study on liposome-mediated transfection of the human interferon-beta (HuIFN-beta) gene into subcutaneously implanted human gliomas in nude mice, we found that HuIFN-beta was produced and secreted by the tumor cells and that the growth of solid tumors was completely inhibited. The present study investig...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930590207
更新日期:1995-06-01 00:00:00
abstract:BACKGROUND:We sometimes encounter hepatocellular carcinoma (HCC) with a central scar and a scalloped tumor margin resembling focal nodular hyperplasia (FNH) in macroscopic appearance. The fibrolamellar variant sometimes shows this appearance; however, this type of HCC can be clearly differentiated from fibrolamellar va...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20615
更新日期:2006-12-01 00:00:00
abstract::The aim of the present study was to demonstrate the practicality of intraoperative fine needle aspiration (FNA) cytology of pancreatic lesions in 43 patients. The indication for performing this procedure was to determine the nature of pancreatic masses. Conclusive cytologic diagnoses were reached in 41 patients who re...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930460407
更新日期:1991-04-01 00:00:00
abstract::The results of treatment with intracavitary bleomycin are reported in twenty patients with a malignant pleural effusion and five patients with malignant ascites. The control rate was 17/20 (85%) patients with malignant pleural effusions and 3/5 (60%) patients with malignant ascites. Toxicities were minimal with fever ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930160312
更新日期:1981-01-01 00:00:00
abstract::Pancreatic cancer is a highly lethal malignancy that often presents at an advanced stage. Surgical resection can prolong survival and offers the only potential for cure. However, pancreatectomy is associated with significant morbidity and mortality. This article reviews perioperative outcomes, post-resection long-term...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.23744
更新日期:2014-10-01 00:00:00
abstract::Seventy tumors of invasive ductal carcinoma of the breast were examined for p53 alteration by the RT-PCR-SSCP method. Sixty-five samples (92.9%) were investigated in the regions of codons 101-200 and 201-300. In total, 16 samples (24.6%) showed p53 gene alteration. We found that p53 gene alteration showed a correlatio...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930560110
更新日期:1994-05-01 00:00:00
abstract:BACKGROUND:Extrapleural pneumonectomy for malignant pleural mesothelioma is considered an aggressive procedure, but symptomatic and quality of life changes are unknown. METHODS:Between 1997 and 2004, 16 consecutive patients underwent extrapleural pneumonectomy for mesothelioma followed by chemo-radiotherapy. Tumor-rel...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21261
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Immune status in the peritoneal cavity of patients with gastric cancer remains largely unknown. To clarify the clinical significance of the host immune response within the peritoneal cavity, we examined the levels of interferon-gamma (IFN-gamma), a type 1 cytokine, and interleukin-10 (IL-10), ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.1131
更新日期:2001-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Tumor markers are a clinical tool frequently used in oncology in association with other clinical and radiologic information. For gastrointestinal cancer, carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA 19-9) tumor markers have found selected clinical application. The use of th...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20107
更新日期:2004-09-15 00:00:00
abstract:BACKGROUND AND OBJECTIVES:To determine the prognostic significance of the colposcopic tumor size in the management of cervical cancer. METHODS:Clinicopathological analysis was performed in 751 consecutive patients with stage IB squamous cervical cancer who were surgically treated in a single institute. The colposcopic...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/1096-9098(200102)76:2<133::aid-jso1024>3.0
更新日期:2001-02-01 00:00:00
abstract::Colorectal cancer progression originates when accumulated genetic and epigenetic alterations cause genomic instability and a malignant phenotype. Subsequent molecular pathway deregulation leads to histopathologic changes that are clinically evident as aberrant crypt foci (ACF) and visualized by high-magnification chro...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.21106
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVE:We retrospectively evaluated the impact of postoperative complications on long-term outcomes after curative resection for colorectal cancer (CRC), using propensity-score analysis (PSA). PATIENTS AND METHODS:We reviewed data from 673 consecutive patients with stage I to III CRC, who underwent curative resecti...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25961
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Recent changes in adjuvant therapies improved the prognosis of metastatic colorectal cancers. Curative resection may be considered, even for both pulmonary and hepatic metastases, but prognostic factors are not well identified. METHODS:From 1995 to 2010, 69 patients had curative resection of pulmonary metas...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23385
更新日期:2013-09-01 00:00:00