Targeted therapy in sarcomas other than GIST tumors.

Abstract:

:Non-GIST soft tissue sarcomas are a heterogeneous grouping of mesenchymal tumors that comprise less than 1% of adult malignancies. Treatment continues to be based on cytotoxic chemotherapy regimens. However, characterization of the molecular pathway deregulations that drive these tumors has led to the emergence of more customized treatment options. In this review, we focus on the multitude of molecular inhibitors targeting angiogenesis and cell cycle pathways being tested in clinical trials.

journal_name

J Surg Oncol

authors

Sborov D,Chen JL

doi

10.1002/jso.23802

subject

Has Abstract

pub_date

2015-04-01 00:00:00

pages

632-40

issue

5

eissn

0022-4790

issn

1096-9098

journal_volume

111

pub_type

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