Induction of antibody response to bromelain-treated mouse erythrocytes by low-density lipoproteins from chicken egg yolk.

Abstract:

:The administration of low-density lipoproteins from chicken egg yolk (EyLDL) to mice induced T-dependent antibodies against bromelain-treated mouse erythrocytes (BrMRBC). The anti-BrMRBC antibodies produced antigen specifically by EyLDL appear to be identical to the antibodies produced polyclonally by lipopolysaccharide (LPS); both antibodies reacted with the liposomes of phosphatidylcholine and showed identical idiotypic patterns. It is suggested that the anti-BrMRBC antibodies may be produced antigen specifically by exogenous antigens to be useful to the mouse. The activation of anti-BrMRBC B cells specifically by EyLDL or polyclonally by LPS resulted in neither expansion nor regression of anti-BrMRBC LPS-reactive B cells. This finding indicates that the population size of anti-BrMRBC LPS-reactive B cells is controlled independently by exogenous specific or polyclonal stimuli.

journal_name

Cell Immunol

journal_title

Cellular immunology

authors

Kawaguchi S

doi

10.1016/0008-8749(88)90195-5

subject

Has Abstract

pub_date

1988-09-01 00:00:00

pages

429-36

issue

2

eissn

0008-8749

issn

1090-2163

pii

0008-8749(88)90195-5

journal_volume

115

pub_type

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