Induction of antibody response to bromelain-treated mouse erythrocytes by low-density lipoproteins from chicken egg yolk.


:The administration of low-density lipoproteins from chicken egg yolk (EyLDL) to mice induced T-dependent antibodies against bromelain-treated mouse erythrocytes (BrMRBC). The anti-BrMRBC antibodies produced antigen specifically by EyLDL appear to be identical to the antibodies produced polyclonally by lipopolysaccharide (LPS); both antibodies reacted with the liposomes of phosphatidylcholine and showed identical idiotypic patterns. It is suggested that the anti-BrMRBC antibodies may be produced antigen specifically by exogenous antigens to be useful to the mouse. The activation of anti-BrMRBC B cells specifically by EyLDL or polyclonally by LPS resulted in neither expansion nor regression of anti-BrMRBC LPS-reactive B cells. This finding indicates that the population size of anti-BrMRBC LPS-reactive B cells is controlled independently by exogenous specific or polyclonal stimuli.


Cell Immunol


Cellular immunology


Kawaguchi S




Has Abstract


1988-09-01 00:00:00














  • Haplotype-specific inhibition of homing of radiolabeled lymphocytes in experimental allergic encephalomyelitis following treatment with anti-IA antibodies.

    abstract::In vivo treatment with anti-IA antibodies has been shown to induce a haplotype-specific inhibition of EAE when the disease was following passive transfer of MBP-sensitized T cells. In order to determine the mechanism by which anti-IA antibody prevents passively transferred EAE, the homing of radiolabeled cells to the ...

    journal_title:Cellular immunology

    pub_type: 杂志文章


    authors: Sriram S,Carroll L

    更新日期:1991-06-01 00:00:00

  • Tissue macrophages as mediators of a healthy relationship with gut commensal microbiota.

    abstract::Mammals and microorganisms have evolved a complex and tightly controlled mutual relationship. This interaction grants protection and energy source for the microorganisms, and on the other hand, provides several immunologic, metabolic and physiological advantages for the host. The gastrointestinal tract (GI) harbors th...

    journal_title:Cellular immunology

    pub_type: 杂志文章,评审


    authors: Nakagaki BN,Vieira AT,Rezende RM,David BA,Menezes GB

    更新日期:2018-08-01 00:00:00

  • The absence of lymphoid suppressor cells in tumor-involved lymph nodes of patients with head and neck cancer.

    abstract::Patients with head and neck cancer often have decreased local or regional immunocompetence. Lymphocytes obtained from tumor-involved or -uninvolved lymph nodes (LNL) of these patients showed low or undetectable levels of antitumor cytotoxicity and low proliferative responses in vitro to interleukin 2 (IL2) or mitogens...

    journal_title:Cellular immunology

    pub_type: 杂志文章


    authors: Letessier EM,Sacchi M,Johnson JT,Herberman RB,Whiteside TL

    更新日期:1990-10-15 00:00:00

  • Prostaglandin E2 and IL-4 provide naive CD4+ T cells with distinct inhibitory signals for the priming of IFN-gamma production.

    abstract::We investigated the effects of prostaglandin E2 and IL-4 on the acquisition of cytokine-producing ability by naive CD4(+) T cells in human umbilical cord blood. The presence of PGE2 or IL-4 at primary stimulation inhibited the production of IFN-gamma at secondary stimulation, and the combination of these stimuli resul...

    journal_title:Cellular immunology

    pub_type: 杂志文章


    authors: Abe N,Katamura K,Shintaku N,Fukui T,Kiyomasu T,Iio J,Ueno H,Tai G,Mayumi M,Furusho K

    更新日期:1997-10-10 00:00:00

  • Characterization of endogenous Chinese hamster ovary cell surface molecules that mediate T cell costimulation.

    abstract::Chinese hamster ovary (CHO) cells are commonly used in the generation of transfectants for use in in vitro costimulation assays. However, we have noted that nontransfected CHO cells can themselves provide a low-level B7/CD28 independent costimulatory signal for CD3-mediated murine T cell activation and IL-2 production...

    journal_title:Cellular immunology

    pub_type: 杂志文章


    authors: Gaglia JL,Mattoo A,Greenfield EA,Freeman GJ,Kuchroo VK

    更新日期:2001-11-01 00:00:00

  • Alloreactive feature of HLA-DP-specific cytotoxic T-cell clone.

    abstract::The alloreactive feature of CD4+ cytotoxic T-cell clone that could specifically lyse the cells bearing DPB1*0202 sequence was described. The clone was generated from a mixed culture of peripheral blood lymphocytes derived from siblings who were HLA-A, B, C, DR, and DQ identical by serological typing and whose DNA sequ...

    journal_title:Cellular immunology

    pub_type: 杂志文章


    authors: Nishimura M,Mitsunaga S,Akaza T,Mitomi Y,Tadokoro K,Juji T

    更新日期:1994-01-01 00:00:00

  • Interleukin-2 induces apoptosis in mouse thymocytes.

    abstract::Interleukins play a role in the process of T-cell development and, like other cytokines, seem able to modulate apoptosis. Interleukin-2 has been reported to inhibit apoptotic cell death of thymocytes induced in vitro by either activation of CD3/TCR complex or treatment with glucocorticoid hormone. We demonstrate here ...

    journal_title:Cellular immunology

    pub_type: 杂志文章


    authors: Migliorati G,Nicoletti I,Pagliacci MC,D'Adamio L,Riccardi C

    更新日期:1993-01-01 00:00:00

  • Dialyzable leukocyte extract (transfer factor) in the treatment of superinfected fistulating tuberculosis of the bone.

    abstract::The effect of the addition of dialyzable leukocyte extract (DLE)(transfer factor) to tuberculostatic drugs in the treatment of superinfected fistulating tuberculosis of bones and joints was evaluated in a controlled study. Eleven patients whose disease had persisted for a mean of 20 +/- 4.8 years and had proved to be ...

    journal_title:Cellular immunology

    pub_type: 杂志文章


    authors: Zielinski CC,Savoini E,Ciotti M,Orani R,Königswieser H,Eibl MM

    更新日期:1984-03-01 00:00:00

  • Construction of hybridomas from nude mice with phenotypes of precursors of regulatory T cells. I. A model for study of development of T-cell function in immune systems.

    abstract::Functional helper and suppressor hybridomas were constructed from fractionated Type II NFR/nude mouse splenocytes which resemble precursors of T cells. After carrier priming with rabbit erythrocytes (RE), splenocytes from Type II NFR/nude mice were fractionated on nylon wool columns. Cells from two distinct fractions ...

    journal_title:Cellular immunology

    pub_type: 杂志文章


    authors: Webb GC,Misfeldt ML,Hanna EE

    更新日期:1984-12-01 00:00:00

  • Studies on phagocytosis of unopsonized rabbit erythrocytes by human monocytes.

    abstract::Monolayers of freshly isolated human monocytes are known to ingest particulate activators of the human alternative complement pathway. The ingestion of rabbit erythrocytes, ER, by human monocytes in serum-free medium was studied. The process is Mg2+-dependent and optimum phagocytic activity was obtained at approximate...

    journal_title:Cellular immunology

    pub_type: 杂志文章


    authors: Chakravarti B

    更新日期:1988-05-01 00:00:00

  • Nitric oxide suppresses IFN-gamma production in the spleen of mercuric chloride-exposed brown Norway rats.

    abstract::Recently we have shown that the generation of IFN-gamma-producing cells (IFN-gamma pc) were severely suppressed in cultures of Con A-stimulated splenocytes obtained from HgCl2-exposed BN but not Lewis rats. Since BN rats develop a TH2-biased polyclonal autoimmune syndrome upon exposure to HgCl2, whereas Lewis rats exh...

    journal_title:Cellular immunology

    pub_type: 杂志文章


    authors: van der Meide PH,de Labie MC,Botman CA,Aten J,Weening JJ

    更新日期:1995-04-01 00:00:00

  • Vaccine-mediated immunity to experimental Mycobacterium tuberculosis is not impaired in the absence of Toll-like receptor 9.

    abstract::Accumulating evidence indicates that inflammatory signals required for maximizing effector T cell generation have opposing effects on the development of memory T cell precursors. Toll-like receptor (TLR)2, and TLR9 significantly contribute to the inflammatory milieu and therefore in this study we examined whether the ...

    journal_title:Cellular immunology

    pub_type: 杂志文章


    authors: Gopalakrishnan A,Dietzold J,Salgame P

    更新日期:2016-04-01 00:00:00

  • Impact of polyunsaturated fatty acids on cytoskeletal linkage of L-selectin.

    abstract::Polyunsaturated fatty acid [omega-3 polyunsaturated fatty acids (omega-3PUFAs)] incorporation into cell membranes has been shown to have potent anti-inflammatory activity, though the mechanisms involved are only partially characterized. Here, we show that PUFA enrichment of T cell membranes decreased the overall expre...

    journal_title:Cellular immunology

    pub_type: 杂志文章


    authors: Leid JG,Jutila MA

    更新日期:2004-04-01 00:00:00

  • FK-506 and cyclosporin A inhibit highly similar signal transduction pathways in human T lymphocytes.

    abstract::This report compares the ability of cyclosporin A and FK-506 to inhibit human T cell activation triggered via cell surface molecules that utilize different intracellular processes. We stimulated highly purified peripheral blood T lymphocytes with mitogens (Con A and PHA), ionomycin + PMA, or monoclonal antibodies spec...

    journal_title:Cellular immunology

    pub_type: 杂志文章


    authors: Lin CS,Boltz RC,Siekierka JJ,Sigal NH

    更新日期:1991-04-01 00:00:00

  • Macrophage defect and inflammatory cell recruitment dysfunction in Salmonella susceptible C3H/HeJ mice.

    abstract::C3H/HeJ mice are homozygous for the Lpsd allele and, as a consequence, are hyporesponsive to all of the biological effects of bacterial lipopolysaccharide (LPS) that have been studied. These mice die in the early phase of infection when inoculated with virulent Salmonella. This susceptibility is also regulated by the ...

    journal_title:Cellular immunology

    pub_type: 杂志文章


    authors: Weinstein DL,Lissner CR,Swanson RN,O'Brien AD

    更新日期:1986-10-01 00:00:00

  • Macrophage binding of cells resistant and sensitive to contact-dependent cytotoxicity.

    abstract::We compared macrophage binding and killing of F5b cells to the binding and killing of P815 mastocytoma cells and to several other nontransformed and transformed cell lines. Formalin fixation of elicited or activated macrophages did not affect binding of F5b or 3T3 cells but did abrogate binding of P815 cells. However,...

    journal_title:Cellular immunology

    pub_type: 杂志文章


    authors: Rosenkrans CF Jr,Chapes SK

    更新日期:1991-03-01 00:00:00

  • Thymocyte maturation following interaction with thymus-derived macrophages.

    abstract::Murine C57BL/6 thymocytes were cultivated together with syngeneic thymus-derived macrophages (TDM phi) for up to 96 hr to determine whether TDM phi participate in thymocyte maturation. The expression level of H-2b and Thy-1.2 antigens served as thymocyte differentiation surface markers as analyzed by flow cytometry. I...

    journal_title:Cellular immunology

    pub_type: 杂志文章


    authors: Zeira M,Gallily R,Stein I,Giloh H

    更新日期:1991-05-01 00:00:00

  • The regulation of resistance to Schistosoma mansoni by a soluble alpha/beta TCR analog, produced by a cloned T cell hybridoma.

    abstract::Immunity to Schistosoma mansoni is regulated by an auto-anti-idiotypic network. The T cells in this network interact through soluble regulatory factors. These studies describe a soluble suppressor-inducer factor (TsiF) derived from TCR+ suppressor-inducer clone Q37. Q37 is the fusion product of CD4+ T cells derived fr...

    journal_title:Cellular immunology

    pub_type: 杂志文章


    authors: Perrin PJ,Phillips SM

    更新日期:1993-06-01 00:00:00

  • PICOT, protein kinase C theta-interacting protein, is a novel regulator of FcepsilonRI-mediated mast cell activation.

    abstract::PICOT (PKC-interacting cousin of thioredoxin) consists of one thioredoxin homology domain in the N-terminal and two tandem PICOT homology domains in the C-terminal. PICOT specifically interacts with protein kinase C theta (PKC-theta) via its thioredoxin homology domain and acts as an important modulator of T cell rece...

    journal_title:Cellular immunology

    pub_type: 杂志文章


    authors: Kato N,Motohashi S,Okada T,Ozawa T,Mashima K

    更新日期:2008-01-01 00:00:00

  • In vivo mechanisms of acquired thymic tolerance.

    abstract::Injection of antigen into the thymus of adult animals induces specific systemic tolerance, but the mechanisms of acquired thymic tolerance are not well understood. To investigate these mechanisms we used a model of intrathymic injection of ovalbumin (OVA) in BALB/c mice. We show an antigen-specific decrease in prolife...

    journal_title:Cellular immunology

    pub_type: 杂志文章


    authors: Chen W,Issazadeh S,Sayegh MH,Khoury SJ

    更新日期:1997-08-01 00:00:00

  • Lipopolysaccharide induced expression of pentraxin 3 in human neutrophils and monocyte-derived macrophages.

    abstract::Pentraxin 3 (PTX3) is a prototype protein of long pentraxin. PTX3 is produced by various cells, such as monocytes/macrophages (Mphis) in response to lipopolysaccharide (LPS) and proinflammatory signals. We performed immunoblotting, immunohistochemical staining, reverse transcriptase-polymerase chain reaction (RT-PCR),...

    journal_title:Cellular immunology

    pub_type: 杂志文章


    authors: Imamura M,Kawasaki T,Savchenko AS,Ohashi R,Jiang S,Miyamoto K,Ito Y,Iwanari H,Sagara M,Tanaka T,Hamakubo T,Kodama T,Uchiyama M,Naito M

    更新日期:2007-08-01 00:00:00

  • Atorvastatin decreases Toll-like receptor 4 expression and downstream signaling in human monocytic leukemia cells.

    abstract:PURPOSE:We aim to evaluate the effects of atorvastatin on the expression of Toll-like receptor (TLR4) protein and mRNA, and to explore their effects on TLR4-dependent downstream signaling in human monocytic leukemia (THP-1) cells. METHODS:TLR4 protein and mRNA expression, levels of NF-κB protein, and expression of TNF...

    journal_title:Cellular immunology

    pub_type: 杂志文章


    authors: Yang SS,Li R,Qu X,Fang W,Quan Z

    更新日期:2012-09-01 00:00:00

  • Adoptive transfer of resistance to murine retrovirus-induced immune suppression.

    abstract::Infection of certain strains of mice, such as C57BL/6 and C57BL/10 [B10], with LP-BM5 murine leukemia virus (MuLV) rapidly causes a profound and lethal immune suppression. The H2d congenic strain of B10, B10.D2, is resistant to disease, but B10 x B10.D2 F1 mice are susceptible, indicating that disease sensitivity is d...

    journal_title:Cellular immunology

    pub_type: 杂志文章


    authors: Gilmore GL

    更新日期:1996-04-10 00:00:00

  • Stimulator requirements for primed alloreactive T cells: macrophages and dendritic cells activate T cells across all genetic disparities.

    abstract::The cellular requirements for stimulating primed alloreactive T cells have been investigated. In vitro-primed secondary alloreactive cells, long-term lines, and Ly 1+2- noncytolytic clones which reacted with allo-H-2K, D, or Mls (M locus) antigens were tested. The data indicated that a specialized antigen-presenting c...

    journal_title:Cellular immunology

    pub_type: 杂志文章


    authors: Sunshine GH,Mitchell TJ,Czitrom AA,Edwards S,Glasebrook AL,Kelso A,MacDonald HR

    更新日期:1985-03-01 00:00:00

  • Tumor necrosis factor (TNF alpha) regulates intestinal mucus production during salmonellosis.

    abstract::Mucus production by goblet cells in the gastrointestinal tract following Salmonella typhimurium infection using a ligated ileal loop model in mice was investigated. Assessment of the morphology of the loop tissue after Salmonella challenge revealed generalized tissue inflammation, characterized by edema and an inflamm...

    journal_title:Cellular immunology

    pub_type: 杂志文章


    authors: Arnold JW,Klimpel GR,Niesel DW

    更新日期:1993-10-15 00:00:00

  • Intravital imaging of skin infections.

    abstract::Intravital imaging of cutaneous immune responses has revealed intricate links between the skin's structural properties, the immune cells that reside therein, and the carefully orchestrated migratory dynamics that enable rapid sensing and subsequent elimination of skin pathogens. In particular, the development of 2-pho...

    journal_title:Cellular immunology

    pub_type: 杂志文章,评审


    authors: Zaid A

    更新日期:2020-04-01 00:00:00

  • In vitro antitumor immune response induced by dendritic cells transduced with human livin α recombinant adenovirus.

    abstract::Transduction with recombinant, replication-defective adenoviral (rAd) vectors encoding a transgene is an efficient method for gene transfer into human dendritic cells (DCs). Livin is a good candidate for cancer immunotherapy since it is overexpressed in most common human cancers, poorly expressed in most normal adult ...

    journal_title:Cellular immunology

    pub_type: 杂志文章


    authors: Xie J,Guo X,Liu F,Luo J,Duan F,Tao X

    更新日期:2015-09-01 00:00:00

  • Effect of orexin-A on phagocytic activity of peritoneal macrophage in starved rats.

    abstract::The aim of this study was to investigate the effect of fasting-induced orexin-A (OXA) on inflammation and macrophage phagocytic activity. Fifty six male wistar rats were fasted for 36 h to stimulate OXA synthesis. In 24 rats, air pouches were induced subcutaneously in the intrascapular area. After (6 h) carrageenan in...

    journal_title:Cellular immunology

    pub_type: 杂志文章


    authors: İzgüt-Uysal VN,Gemici B,Tan R

    更新日期:2011-01-01 00:00:00

  • Intranasal delivery of cationic liposome-protamine complex mRNA vaccine elicits effective anti-tumor immunity.

    abstract::Immunization with synthetic mRNA encoding tumor-associated antigens is an emerging vaccine strategy for the treatment of cancer. In order to prevent mRNA degradation, promote antigen-presenting cells antigen presentation, and induce an anti-tumor immune response, we investigated the nasal administration of mRNA vaccin...

    journal_title:Cellular immunology

    pub_type: 杂志文章


    authors: Mai Y,Guo J,Zhao Y,Ma S,Hou Y,Yang J

    更新日期:2020-08-01 00:00:00

  • Role of macrophages as modulators but not as autonomous accessory cells in primary antibody response.

    abstract::The role of macrophages (M phi) in the in vitro primary antibody response of murine lymphocytes to sheep erythrocytes was investigated. Peritoneal M phi were activated to express Ia antigens either in vitro or in vivo. Nonactivated Ia- M phi were also examined. We observed that only Ia- M phi but also Ia+ M phi failed...

    journal_title:Cellular immunology

    pub_type: 杂志文章


    authors: Komatsubara S,Hirayama Y,Inaba K,Naito K,Yoshida K,Kawai J,Muramatsu S

    更新日期:1985-10-15 00:00:00