Abstract：
:This study tested whether sole neurobiological or sociodynamic explanations of alcohol dependence altered respondents' attitudes toward alcohol-dependent patients. We investigated the effect of information leaflets on 444 participants: one group received an information leaflet with a biological explanation of AD; the other received a leaflet with a sole sociodynamic explanation of AD. A third, control group did not receive any leaflet. Afterwards, all three groups completed a questionnaire regarding their attitudes toward ADPs and their opinions of the underlying causes of AD. We found a significant group difference with regard to participants' agreement with a neurobiological explanation of AD. Moreover, respondents in the neurobiological intervention group considered the characteristics of ADP to be significantly more positive than those in the sociodynamic group. Furthermore, they were significantly less likely to accept AD as a self-inflicted disease. Correlation analysis revealed associations between accepting the sociodynamic disease model and all of the stigmatization dimensions tested in our questionnaire. In summary, stigmatization toward ADP was closely associated with the agreement with sociodynamic origins of AD in this study.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Heberlein A,Schuster R,Ziert Y,Opfermann B,Bleich S,Hillemacher Tdoi
10.1016/j.psychres.2013.12.040subject
Has Abstractpub_date
2014-03-30 00:00:00pages
766-70issue
3eissn
0165-1781issn
1872-7123pii
S0165-1781(13)00834-2journal_volume
215pub_type
杂志文章abstract：:Screening for psychiatric disorders may be hampered by traditional measures that increase participant burden and elicit negative responses via denial and social desirability biases. This study examined the utility of a wellbeing measure to identify psychopathology and suicide risk in adolescent participants. 1,579 stu...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.07.034
更新日期：2018-10-01 00:00:00
abstract：:We examined the associations of current alcohol consumption with brain morphometric measures in a healthy, community-dwelling cohort. Cranial T1-weighted 3D-structural MRI scans were obtain in 383 adults (men=211) aged 60-64 years, randomly selected form the larger PATH Through Life study. Voxel-based morphometric ana...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2007.08.009
更新日期：2008-05-30 00:00:00
abstract：:Some, but not all studies have reported that a single dose of benzodiazepine affects growth hormone (GH) and cortisol secretion in healthy volunteers. The majority of studies that found GH elevations after benzodiazepine administration did not use placebo trials. The present placebo-controlled investigation determined...
journal_title：Psychiatry research
pub_type： 临床试验,杂志文章
doi：10.1016/0165-1781(86)90014-4
更新日期：1986-08-01 00:00:00
abstract：:The study reported herein explored the comprehension of metaphor and irony in schizophrenia during remission, and examined the role of IQ and a theory of mind. Performance of 29 Schizophrenic patients in remission and 22 healthy controls was compared on metaphor and irony comprehension tasks and first- and second-orde...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2006.04.002
更新日期：2008-01-15 00:00:00
abstract：:Energy metabolism and immunity are characterized as abnormal in schizophrenia. Because these two systems are highly coordinated, we measured expression of prototypic obesogenic and immunogenic genes in freshly harvested PBMC from controls and participants with schizophrenia. We report significant increases in PPARγ, S...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2014.11.007
更新日期：2015-01-30 00:00:00
abstract：:MIR137, a brain expressed miRNA, has been identified as a top novel susceptibility gene for schizophrenia (SZ). 230 healthy participants completed the Stroop test and were genotyped for a functional Variable Number Tandem Repeat (VNTR) in MIR137 gene. MIR137 VNTR genotypes were associated with differences in Stroop fa...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2016.01.006
更新日期：2016-02-28 00:00:00
abstract：:While social anhedonia is a promising indicator of vulnerability to schizophrenia, it remains uncertain whether anhedonia is a core feature of schizotypy or merely a secondary associated characteristic. This issue was examined by comparing dimensional scores on schizophrenia spectrum personality disorder symptoms deri...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2006.06.002
更新日期：2007-01-15 00:00:00
abstract：:In order to investigate electroencephalographic (EEG) biomarkers of auditory processing for schizophrenia, we studied a group with a well known high-risk profile: patients with 22q11.2 deletion syndrome (22q11 DS) have a 30% risk of developing schizophrenia during adulthood. We performed high-density EEG source imagin...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2012.09.002
更新日期：2013-05-30 00:00:00
abstract：:Jumping to conclusions (JTC) is defined as a tendency to make decisions based on insufficient information. JTC has been reported in patients with psychosis, but the mechanisms of this cognitive bias remain unknown. The main aim of our study was to investigate the relationship between JTC and neuropsychological functio...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2019.01.035
更新日期：2019-03-01 00:00:00
abstract：:Several lines of evidence suggest that lactate metabolism may be altered in panic disorder. We recently reported exaggerated increases in serum lactate in panic patients following hyperventilation during glucose infusion. In the current study, lactate metabolism was stimulated by hyperventilation following glucose ing...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(91)90020-p
更新日期：1991-09-01 00:00:00
abstract：:In this study, we investigated whether polymorphisms of the dopamine D4 receptor (DRD4) gene were associated with psychotic symptomatology rather than with a unique diagnosis such as schizophrenia. A number of association studies between the DRD4 gene 48 bp-VNTR polymorphism at exon 3 and psychotic disorders have been...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2006.12.011
更新日期：2007-12-03 00:00:00
abstract：:Resting state functional magnetic resonance imaging (fMRI) was used to measure whole brain functional connectivity within specific networks hypothesised to be more affected in dementia with Lewy bodies (DLB) (a disease characterised by prominent attentional deficits, spontaneous motor features of parkinsonism and depr...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2014.06.004
更新日期：2014-09-30 00:00:00
abstract：:Several studies have demonstrated that patients with schizophrenia are impaired in recognizing emotions from facial expressions and in appreciating other people's mental states--the latter commonly referred to as 'theory of mind.' The question as to how social cognitive skills relate to patients' actual social behavio...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2004.10.007
更新日期：2005-02-28 00:00:00
abstract：:Recent studies have implicated dopamine and the basal ganglia circuits in the pathophysiology of social phobia. Twenty-two patients who met DSM-III-R criteria for social phobia and 22 age- and sex-matched control subjects underwent magnetic resonance imaging (MRI). MRI was performed with a 1.5 Tesla General Electric S...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(94)90118-x
更新日期：1994-04-01 00:00:00
abstract：:Most investigators have measured binding of 3H-imipramine to platelet membranes, but some of the preparations may have contained varying proportions of intracellular protein because of contamination with incompletely lysed platelets. Since binding to membranes has been expressed with reference to the amount of protein...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(88)90070-4
更新日期：1988-11-01 00:00:00
abstract：:A range of executive function (EF) deficits have been associated with Borderline Personality (BPD), a disorder characterized by high rates of suicide. However, the role of EF and suicide risk in BPD has not been examined. This exploratory study compared working memory, Stroop interference, motor inhibition (SSRT) and ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2011.10.008
更新日期：2012-03-30 00:00:00
abstract：:Evidence on mental illness stigma abounds yet little is known about public perceptions of intellectual disability. This study examined causal beliefs about intellectual disability and schizophrenia and how these relate to awareness of the condition and social distance. UK lay people aged 16+(N=1752), in response to vi...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2016.06.019
更新日期：2016-09-30 00:00:00
abstract：:Childhood adversity is associated with a range of mental disorders, functional impairment and higher health care costs in adulthood. In this study we evaluated if childhood adversity was predictive of adverse clinical and functional outcomes and health care costs in a sample of patients at ultra-high risk (UHR) for de...
journal_title：Psychiatry research
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.psychres.2016.11.014
更新日期：2017-01-01 00:00:00
abstract：:Major depressive disorder (MDD) is associated with abnormalities in emotional/cognitive processing and low reward sensitivity. The habenula has a pivotal role in these processes that may contribute to depression. However, there has been little research on the abnormal connectivity between the habenula and whole brain ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2020.112837
更新日期：2020-01-31 00:00:00
abstract：:This study examines the relationships between internalized stigma, psychological well-being, and subjective well-being in a sample of people with mental illness. We conducted a cross-sectional study with 213 outpatients from the Spanish public social care network. The results showed that (a) internalized stigma was si...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2015.06.029
更新日期：2015-08-30 00:00:00
abstract：:We developed a semiautomatic method termed "cortical circumferential profiling" for objective analysis of cerebral cortex function in emission tomographic neuroimaging studies. This method treats cortex as a continuous ring near the outer brain edge. A computer algorithm samples the cortex at 60 contiguous, equiangula...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0925-4927(91)90008-e
更新日期：1991-11-01 00:00:00
abstract：:In Chinese adolescents exposed to the Wenchuan earthquake, we used the Children's Revised Impact of Event Scale (CRIES) as the screening tool, and Post-traumatic Cognitions Inventory (PTCI) and the Social Support Rating Scale (SSRS) were used to assess the cognitive status and their social supports, to evaluate the pr...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2010.12.016
更新日期：2011-10-30 00:00:00
abstract：:Catechol-O-methyltransferase (COMT) is a candidate gene for the pathogenesis of some psychiatric disorders. The aim of this study is to examine the role of the COMT gene Val158Met polymorphism on the clinical aspects of bipolar disorder including symptomatology and therapeutic response. This study comprised 144 unrela...
journal_title：Psychiatry research
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.psychres.2008.09.011
更新日期：2010-01-30 00:00:00
abstract：:Higher electromyographic (EMG) activity levels of corrugator and zygomatic face muscles have been reported to be pretreatment predictors of better clinical outcome in depressed patients. We tested this possibility in 29 drug-free, rigorously diagnosed subjects by measuring low-level EMG activity of corrugator and zygo...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(84)90082-9
更新日期：1984-12-01 00:00:00
abstract：:Previous work suggests that iomazenil (formerly known as Ro 16-0154) is a useful ligand for static imaging of the benzodiazepine (BZ) receptor with single photon emission computed tomography (SPECT). The present study evaluated the feasibility of dynamic SPECT imaging of cerebral radioactivity following intravenous [1...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0925-4927(92)90001-k
更新日期：1992-08-01 00:00:00
abstract：:In the present study the defense styles were assessed in heroin dependent inpatients to verify whether they used less adaptive defense mechanisms compared to healthy controls and to evaluate if immature defense styles are related with childhood traumas, while controlling the effect of age, temperament and character on...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2012.07.026
更新日期：2012-12-30 00:00:00
abstract：:This article illustrates how Exploratory Data Analysis (EDA) can complement conventional statistical methods in evaluating psychiatric tests. Using one recent EDA computer program, we evaluated the ability of repeated psychiatric screening tests (the General Health Questionnaire [GHQ]) to predict medical and psychiatr...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(91)90009-e
更新日期：1991-10-01 00:00:00
abstract：:To study different aspects of regional pre-synaptic brain (123)I-beta-CIT uptake on serotonin and dopamine re-uptake sites in drug-free suicide attempters in comparison with age- and sex matched control subjects, single photon emission computed tomography (SPECT) measurements were analysed for regional serotonin re-up...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2006.06.001
更新日期：2006-12-01 00:00:00
abstract：:Patients with borderline personality disorder (BPD) suffer from various impairments in emotional functioning such as affective instability, inappropriate anger and unstable relationships. These deficits may influence two fundamental motivational systems, the behavioral inhibition system (BIS) and behavioral activation...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2014.04.027
更新日期：2014-08-15 00:00:00
abstract：:This study describes 17 publicly available cases of animal hoarding, a special manifestation of hoarding disorder. The cases, which included court documents, animal service documents, photographs, and newspaper clippings, were reviewed by Masters-level clinicians and a veterinarian in private practice. The veterinaria...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.12.127
更新日期：2019-02-01 00:00:00
