Dysplasia and early carcinoma in inflammatory bowel disease and colorectal adenomas.

abstract：:(90)Yttrium (Therasphere) microspheres administered via hepatic artery are a valuable option for treatment of hepatocellular carcinoma. This therapy targets tumor nodules while largely sparing hepatic parenchyma. This retrospective study examines liver explants from 13 adult patients with hepatocellular carcinoma who ...

journal_title：Human pathology

authors： Nalesnik MA,Federle M,Buck D,Fontes P,Carr BI

更新日期：2009-01-01 00:00:00

abstract：:Laminin and collagen have been studied in several tumor types and their immunomorphological expression correlated with tumor morphogenesis, local invasiveness, and metastatic behavior. In a series of 53 cases of pleomorphic adenomas (PA) and 16 cases of carcinomas ex-pleomorphic adenoma (Ca ex-PA), we investigated by ...

journal_title：Human pathology

authors： Félix A,Rosa JC,Fonseca I,Cidadão A,Soares J

更新日期：1999-08-01 00:00:00

abstract：:To increase awareness of the possible coexistence of an ovarian and breast carcinoma in a BRCA1 mutation carrier, we describe a patient with primary ovarian cancer who developed distant metastases after 3 years and again after 6 years. Surprisingly, at that time an occult breast carcinoma was identified to be the orig...

journal_title：Human pathology

authors： Kuenen-Boumeester V,Den Bakker M,Dinjens WN,Seynaeve C

更新日期：2004-05-01 00:00:00

abstract：:Intraprostatic spermatozoa (IS) have been demonstrated in only 2 articles in the literature reporting on postmortem prostates. Intraprostatic spermatozoa have not been previously described in radical prostatectomies. This is the first study that describes the presence of IS in radical prostatectomies with prostatic ca...

journal_title：Human pathology

authors： Chen X,Zhao J,Salim S,Garcia FU

更新日期：2006-03-01 00:00:00

abstract：:Soft tissue myoepithelial tumors, a recently defined entity, include benign and malignant lesions showing a considerable morphological and immunohistochemical heterogeneity. EWSR1 rearrangements are well recognized in this tumor type, and some of the partner genes have been identified. Herein we describe a soft tissue...

journal_title：Human pathology

authors： Flucke U,Mentzel T,Verdijk MA,Slootweg PJ,Creytens DH,Suurmeijer AJ,Tops BB

更新日期：2012-05-01 00:00:00

abstract：:The presence and morphology of high-grade prostatic intraepithelial neoplasia (H-PIN) was blindly evaluated in 40 totally embedded radical prostatectomy specimens of patients with prostate cancer randomized to either a 3 (n = 18) or 6 months (n = 22) combined androgen blockade regimen before surgery. In 5 cases, neo-a...

journal_title：Human pathology

authors： van der Kwast TH,Labrie F,Tetu B

更新日期：1999-12-01 00:00:00

abstract：:We have previously reported that MUC2 apomucin was highly expressed in noninvasive tumors of the pancreas (intraductal papillary tumor [IdPT]) and liver (bile duct cystadenocarcinoma [BdCC]), which show more favorable outcomes than invasive carcinomas. In contrast, MUC2 was rarely expressed in invasive carcinomas of t...

journal_title：Human pathology

authors： Yonezawa S,Sueyoshi K,Nomoto M,Kitamura H,Nagata K,Arimura Y,Tanaka S,Hollingsworth MA,Siddiki B,Kim YS,Sato E

更新日期：1997-03-01 00:00:00

abstract：:Medical culture espouses patient interaction based on detached concern, where emotional attachment to patients is attenuated to preserve objectivity. The body is viewed as nonliving matter in motion. Alternatively, the cadaver may be considered a gift. To receive so awesome a gift is an extraordinary privilege; acknow...

journal_title：Human pathology

authors： Sukol RB

更新日期：1995-07-01 00:00:00

abstract：:Ewing sarcoma (ES) is an aggressive malignant small round cell tumor that arises in bone or soft tissue of adolescents and young adults. A characteristic molecular finding in ES is EWSR1 gene fusion with ETS (erythroblast transformation-specific) family genes including FLI1 (~90%) and ERG (>5%). Here we report our exp...

journal_title：Human pathology

authors： Warren M,Weindel M,Ringrose J,Venable C,Reyes A,Terashima K,Rao P,Chintagumpala M,Hicks MJ,Lopez-Terrada D,Lu XY

更新日期：2013-10-01 00:00:00

abstract：:Previous studies indicated that microRNA (miR)-675 and its precursor lncRNA H19 were both overexpressed in glioma tissues, and H19 might play an oncogenic role. To investigate the involvement of miR-675 in gliomas and its underlying mechanisms, we here collected candidate target genes of miR-675-5p from miRTarBase (ht...

journal_title：Human pathology

authors： Zheng Y,Lu X,Xu L,Chen Z,Li Q,Yuan J

更新日期：2017-11-01 00:00:00

abstract：:Of the approximately 635 residents in each year of pathology training, about 165 are already meeting the Pathology Board's proposed requirement for a fifth year of resident training. The cost of a fifth year of training for the other 470 residents is estimated to be approximately $20 million. Options for avoiding this...

journal_title：Human pathology

authors： Colloton JW

更新日期：1984-08-01 00:00:00

abstract：:Tumor budding (TB) in colorectal carcinoma (CRC) is related to epithelial-mesenchymal transition and has been recently characterized as an indicator of poor prognosis along with lymphovascular tumor emboli, perineural invasion, and an infiltrative growth pattern. Mutations in the genes of the Ras-mitogen-activated pro...

journal_title：Human pathology

authors： Jang S,Hong M,Shin MK,Kim BC,Shin HS,Yu E,Hong SM,Kim J,Chun SM,Kim TI,Choi KC,Ko YW,Kim JW

更新日期：2017-07-01 00:00:00

abstract：:Twelve cases of pure adenoid cystic carcinoma of the breast were reviewed. Patients ranged in age from 34 to 69 years. Seven carcinomas were in the right breast, and five in the left; five of the 12 were located in the central region of the breast, five in the upper outer quadrant, and the two in the upper inner and l...

journal_title：Human pathology

authors： Ro JY,Silva EG,Gallager HS

更新日期：1987-12-01 00:00:00

abstract：:We report the clinical, histologic, and genetic findings of concurrent neuroblastoma and nephroblastoma in an infant with Fanconi's anemia (FA). Both tumors had characteristic chromosomal aberrations. In particular, the neuroblastoma showed a gain of chromosome 17q, considered an important factor for prognosis. But un...

journal_title：Human pathology

authors： Bissig H,Staehelin F,Tolnay M,Avoledo P,Richter J,Betts D,Bruder E,Kühne T

更新日期：2002-10-01 00:00:00

abstract：:A comparative study of the immunohistochemical (Stem cell leukemia/T-cell acute leukemia [SCL/TAL-1] protein expression) and genotypic (deletions in the SCL/tal-1 gene) findings in T-acute lymphoblastic leukemia (T-ALL) is presented. Formalin-fixed tissue from 50 cases of T-ALL were stained with a novel monoclonal ant...

journal_title：Human pathology

authors： Chetty R,Pulford K,Jones M,Mathieu-Mahul D,Close P,Hussein S,Pallesen G,Ralfkiaer E,Stein H,Gatter K

更新日期：1995-09-01 00:00:00

abstract：:The mucin profile of 24 endoscopic biopsies of heterotopic gastric mucosa (HGM) of the upper esophagus in adults and a control group of ten cases of Meckel's diverticula containing heterotopic gastric mucosa were studied with two combined histochemical methods: alcian blue pH 2.5/PAS and high iron diamine/alcian blue ...

journal_title：Human pathology

authors： Bogomoletz WV,Geboes K,Feydy P,Nasca S,Ectors N,Rigaud C

更新日期：1988-11-01 00:00:00

abstract：:Isolated submandibular adenopathy developed in a patient who had subacute erythroleukemia. Lymph node biopsy revealed a proliferation of immature cells and scattered foci of dyserythropoietic normoblasts. Since a review of the literature revealed no detailed description of an erythroleukemic lymph node infiltrate, a h...

journal_title：Human pathology

authors： Keifer J,Zaino R,Ballard JO

更新日期：1984-11-01 00:00:00

abstract：:Two cystic lesions that were lined by pseudostratified ciliated columnar epithelium containing goblet cells are described. Both lesions were found in the subarachnoid space between the vertebrobasilar arterial system and the brainstem. One cyst was an incidental finding in a patient who died of orbital phycomycosis. T...

journal_title：Human pathology

authors： Schelper RL,Kagan-Hallet KS,Huntington HW

更新日期：1986-04-01 00:00:00

abstract：:Extratubal secondary trophoblastic implants (ESTI) are a rare complication of conservative laparoscopic procedures for tubal ectopic pregnancies. These implants present with persistent beta-hCG titers postoperatively and are probably the result of disruption of the ectopic pregnancy at salpingostomy or morcellation of...

journal_title：Human pathology

authors： Doss BJ,Jacques SM,Qureshi F,Ramirez NC,Lawrence WD

更新日期：1998-02-01 00:00:00

abstract：:Rhabdomyomas are rare tumors that usually arise within the heart, orocervical, or vulvovaginal regions. The cardiac tumors have a characteristic immature morphology, occur often in association with tuberous sclerosis, and are regarded as hamartomas rather than true neoplasms. The histogenesis of the extracardiac tumor...

journal_title：Human pathology

authors： Zwick DL,Livingston K,Clapp L,Kosnik E,Yates A

更新日期：1989-04-01 00:00:00

abstract：:Explants from paraspinal muscles of patients with scoliosis were cultured in Millipore diffusion chambers placed in peritoneal cavities of mice. Three and four weeks of incubation produced a predominantly myogenic growth. Cell counts done on paraffin sections and on dissociated cells from the chambers showed that expl...

journal_title：Human pathology

authors： Yarom R,Carmy O,Robin GC,More R

更新日期：1981-07-01 00:00:00

abstract：:Four cases of radiation cystitis that caused diagnostic difficulty because of an epithelial proliferation with architectural complexity and reactive cytologic atypia are described. The patients, 2 male, 2 female, were from 43 to 77 years of age. Two presented with hematuria. Cystoscopy disclosed abnormalities in 3 pat...

journal_title：Human pathology

authors： Baker PM,Young RH

更新日期：2000-06-01 00:00:00

abstract：:Insulin-like growth factor II messenger RNA (mRNA)-binding protein 3 (IMP3) is an oncofetal protein that promotes tumor progression and metastasis in a number of malignancies. However, the clinical significance of IMP3 expression in squamous cell carcinoma (SCC) of the uterine cervix is unclear. In this study, the cor...

journal_title：Human pathology

authors： Wei Q,Yan J,Fu B,Liu J,Zhong L,Yang Q,Zhao T

更新日期：2014-11-01 00:00:00

abstract：:Adamantinoma of long bones is a rare skeletal tumor of unknown origin with epithelial and fibrous elements. The ill-defined distinction between the two components in some cases earlier led to the assumption that these might be derived from the same (mesenchymal) stem cell. In this study, we investigated the distributi...

journal_title：Human pathology

authors： Hazelbag HM,Van den Broek LJ,Fleuren GJ,Taminiau AH,Hogendoorn PC

更新日期：1997-02-01 00:00:00

abstract：:Encapsulated thyroid tumors of follicular cell origin with high-grade features (EFHG) are unusual neoplasms. In current classification schemes, they are called atypical adenomas or follicular, papillary, or poorly differentiated carcinoma. When noninvasive, EFHG create a major therapeutic/diagnostic dilemma stemming f...

journal_title：Human pathology

authors： Rivera M,Ricarte-Filho J,Patel S,Tuttle M,Shaha A,Shah JP,Fagin JA,Ghossein RA

更新日期：2010-02-01 00:00:00

abstract：:A 61-year-old woman was admitted to the hospital because of general fatigue. Laboratory examinations showed hyponatremia, plasma hypo-osmolarity, and inappropriate increased concentration of the plasma antidiuretic hormone (ADH) in the presence of concentrated urine. Magnetic resonance imaging revealed a mass lesion i...

journal_title：Human pathology

authors： Asada Y,Marutsuka K,Mitsukawa T,Kuribayashi T,Taniguchi S,Sumiyoshi A

更新日期：1996-05-01 00:00:00

abstract：:Spindle cell carcinoma (SpCC) is uncommon, with a predilection for the upper aerodigestive tract. Its histogenesis has not been resolved, although most authors support the sarcomatoid carcinoma concept. Ploidy analysis and proliferation indices have not been reported for laryngeal SpCCs. The authors examined the patho...

journal_title：Human pathology

authors： Lewis JE,Olsen KD,Sebo TJ

更新日期：1997-06-01 00:00:00

abstract：:Inflammatory bowel disease-associated colorectal carcinomas (IBD-CRCs) develop in a background of chronic inflammation, and thus, the molecular landscape of these tumors likely differs from that of sporadic colorectal cancer. To add to emerging data on molecular alterations present in these tumors, we analyzed our ins...

journal_title：Human pathology

authors： Alpert L,Yassan L,Poon R,Kadri S,Niu N,Patil SA,Mujacic I,Montes D,Galbo F,Wurst MN,Zhen CJ,Cohen RD,Rubin DT,Pekow JR,Weber CR,Xiao SY,Hart J,Segal J,Setia N

更新日期：2019-07-01 00:00:00

abstract：:An immunohistochemical survey of X-linked inhibitor of apoptosis (XIAP) expression in mammary carcinoma was performed. XIAP, the most potent of the inhibitor of apoptosis family of caspase inhibitors, has been linked to tumor aggressiveness and therapeutic resistance in several malignancies and is considered an attrac...

journal_title：Human pathology

authors： Jaffer S,Orta L,Sunkara S,Sabo E,Burstein DE

更新日期：2007-06-01 00:00:00

abstract：:AT-rich interactive domain 1A (ARID1A) is tumor suppressor gene that interacts with BRG1 adenosine triphosphatase to form a SWI/SNF chromatin remodeling protein complex. Inactivation of ARID1A has been described in several neoplasms, including epithelial ovarian and endometrial carcinomas, and has been correlated with...

journal_title：Human pathology

authors： Faraj SF,Chaux A,Gonzalez-Roibon N,Munari E,Ellis C,Driscoll T,Schoenberg MP,Bivalacqua TJ,Shih IeM,Netto GJ

更新日期：2014-11-01 00:00:00