SCL/Tal-1 expression in T-acute lymphoblastic leukemia: an immunohistochemical and genotypic study.

abstract：:CD10 is common in B-precursor acute lymphoblastic leukemia (ALL) but is rare in acute myeloid leukemia (AML). However, until recently, analysis for CD10 has generally required fresh or frozen tissue. 56C6 is a monoclonal antibody that is now commercially available for the detection of CD10 in routinely processed paraf...

journal_title：Human pathology

authors： Bavikatty NR,Ross CW,Finn WG,Schnitzer B,Singleton TP

更新日期：2000-09-01 00:00:00

abstract：:Pulmonary endodermal tumor resembling fetal lung describes an uncommon neoplasm of the lung which also has been referred to as pulmonary blastoma and adenocarcinoma of fetal lung type. We describe five cases which fall within a narrow band on the spectrum of pulmonary neoplasms with both epithelial and mesenchymal fea...

journal_title：Human pathology

authors： Nakatani Y,Dickersin GR,Mark EJ

更新日期：1990-11-01 00:00:00

abstract：:Infiltrating ductal carcinoma of the breast is histologically heterogeneous and may be subdivided into three main types (A, B, and C) which correlate with the likelihood of long-term survival. Examples of each type were tested against three monoclonal antibodies (H59, H71, and H72) prepared against the breast cancer c...

journal_title：Human pathology

authors： Yuan D,Dawson PJ

更新日期：1987-11-01 00:00:00

abstract：:A membrane-bound, Ca2-dependent complex of the cofactor factor Va and the enzyme factor Xa comprises the prothrombinase coagulation complex, which catalyzes the proteolytic conversion of prothrombin to thrombin. In normal hemostasis, the platelet is presumed to supply the surface membrane and thus constitutes the site...

journal_title：Human pathology

authors： Tracy PB,Mann KG

更新日期：1987-02-01 00:00:00

abstract：:We studied the histopathologic, immunohistochemical, and ultrastructural features of the extracellular matrix (ECM) in 20 immunologically defined large-cell lymphomas, including immunoblastic sarcoma of B cells (three patients), peripheral T cell lymphoma (five patients), large non-cleaved follicular center cell (FCC)...

journal_title：Human pathology

authors： McCurley TL,Gay RE,Gay S,Glick AD,Jones MR,Haralson MA,Collins RD

更新日期：1989-02-01 00:00:00

abstract：:All cases of primary breast carcinoma seen at the George Washington University Medical Center between 1971 and 1975 and between 1981 and 1986 were reviewed, and examples of pure and mixed infiltrating cribriform carcinoma (ICC) were identified. The relative frequency of ICC did not change significantly from the earlie...

journal_title：Human pathology

authors： Venable JG,Schwartz AM,Silverberg SG

更新日期：1990-03-01 00:00:00

abstract：:We studied c-erbB-2, p53, and nm23 gene products in 112 primary breast carcinomas. Fifty patients were aged 35 years or younger, and 62 were aged 36 to 50. Clinicopathological criteria including clinical stage, hormone receptor status, histological types, histological grades, and lymph node status, were reviewed. Dise...

journal_title：Human pathology

authors： Bertheau P,Steinberg SM,Merino MJ

更新日期：1998-04-01 00:00:00

abstract：:Papillary carcinoma of the breast is a variant of predominantly intraductal carcinoma characterized by a papillary growth pattern with fibrovascular support. Loss of heterozygosity (LOH) was evaluated at multiple chromosomal loci (including loci reported to show frequent genetic alterations in breast cancer) to determ...

journal_title：Human pathology

authors： Lininger RA,Park WS,Man YG,Pham T,MacGrogan G,Zhuang Z,Tavassoli FA

更新日期：1998-10-01 00:00:00

abstract：:Small-cell osteosarcoma is a rare form of osteosarcoma and often poses difficulty in differential diagnosis when tissue samples do not include any diagnostic osteoid. By light microscopy, it may be difficult to distinguish small-cell osteosarcoma from other small-cell neoplasms, especially Ewing's sarcoma and mesenchy...

journal_title：Human pathology

authors： Dickersin GR,Rosenberg AE

更新日期：1991-03-01 00:00:00

abstract：:We report three cases of follicular dendritic cell sarcoma (FDCS) showing a hitherto undescribed histological pattern consisting of nodular tumor growth associated with small B lymphocytes. FDCS tumor cells consistently showed large epithelioid features and were intermingled with small lymphocytes in the nodules in tw...

journal_title：Human pathology

authors： Lorenzi L,Lonardi S,Petrilli G,Tanda F,Bella M,Laurino L,Rossi G,Facchetti F

更新日期：2012-02-01 00:00:00

abstract：:Tissues obtained from 600 routine autopsies were studied. Mineral oil lipidosis was present in the spleen (76 per cent), liver (45 per cent), bone marrow (26 per cent), and lymph nodes; more than 50 per cent of the lymph nodes from the mesentery, porta hepatis, and mediastinum were affected. Mineral oil and its metabo...

journal_title：Human pathology

authors： Cruickshank B,Thomas MJ

更新日期：1984-08-01 00:00:00

abstract：:To investigate the expression and clinical significance of long noncoding RNA (lncRNA) in gastric cancer, we applied microarray analysis to obtain expression profiles of protein-coding genes and lncRNAs in tumor and paired adjacent nontumor tissues. We found that 41 lncRNAs were up-regulated and 31 lncRNAs were down-r...

journal_title：Human pathology

authors： Li L,Wang YY,Mou XZ,Ye ZY,Zhao ZS

更新日期：2018-08-01 00:00:00

abstract：:Three of eight female patients with cytomegalovirus disease had evidence of ovarian infection at autopsy. All three patients with ovarian lesions were postmenopausal; the remaining five were premenopausal. The lesions, which may be bilateral and may occur without evidence of cytomegalovirus infection elsewhere, are di...

journal_title：Human pathology

authors： Subietas A,Deppisch LM,Astarloa J

更新日期：1977-05-01 00:00:00

abstract：:Benign lymphocytic angiitis and granulomatosis is a T-cell lymphoproliferative disorder confined to the lung and corresponding to a low-grade angiocentric immunoproliferative lesion. Controversy remains as to whether these lesions are lymphomas. We report such a case in an 8-year-old patient with Burkitt's lymphoma in...

journal_title：Human pathology

authors： Vergier B,Capron F,Trojani M,Labouyrie E,Ferrer J,Eghbali H,Merlio JP,de Mascarel A

更新日期：1992-10-01 00:00:00

abstract：:An increase in S100 protein-positive cells has been reported in inflammatory bowel diseases, mainly Crohn disease. These cells were interpreted as myeloid-derived dendritic cells, chiefly in follicular areas. We were prompted to assess the nature of these cells in interfollicular areas of inflamed colonic mucosa in ul...

journal_title：Human pathology

authors： Mosnier JF,Jarry A,Camdessanché JP,Antoine JC,Laboisse CL

更新日期：2009-08-01 00:00:00

abstract：:Metanephric stromal tumors (MSTs) are rare renal stromal tumors that predominantly affect children. They belong to the metanephric family of tumors, along with metanephric adenofibroma and metanephric adenoma. The previous documentation of BRAF exon 15 mutations in 88% of metanephric adenomas and in isolated cases of ...

journal_title：Human pathology

authors： Marsden L,Jennings LJ,Gadd S,Yu M,Perlman EJ,Cajaiba MM

更新日期：2017-02-01 00:00:00

abstract：:Mammary analogue secretory carcinoma (MASC) is a recently described salivary gland tumor that has morphologic features similar to secretory carcinoma of the breast and that also harbors the same ETV6 translocation. Diffuse mammaglobin and S-100 immunoreactivity are used to differentiate MASC from its morphologic mimic...

journal_title：Human pathology

authors： Patel KR,Solomon IH,El-Mofty SK,Lewis JS Jr,Chernock RD

更新日期：2013-11-01 00:00:00

abstract：:Head and neck squamous cell carcinoma (HNSCC) typically affects male smokers older than 55 years. Recently, an increase in the incidence of HNSCC in young adults has been recognized, many of them nonsmokers and females. Functional inactivation of p16 is known to be a common event in HNSCC, mainly by either deletion or...

journal_title：Human pathology

authors： O'Regan EM,Toner ME,Finn SP,Fan CY,Ring M,Hagmar B,Timon C,Smyth P,Cahill S,Flavin R,Sheils OM,O'Leary JJ

更新日期：2008-03-01 00:00:00

abstract：:Gastric heterotopia of the intestinal tract can have a diverse clinicopathologic presentation, resulting in a diagnostic dilemma. We present a series of four cases, two male and two female patients with age range of 31-82 years, found in the duodenum, jejunum, and transverse colon. The most common and rather unusual c...

journal_title：Human pathology

authors： Nasir A,Amateau SK,Khan S,Simpson RW,Snover DC,Amin K

更新日期：2018-04-01 00:00:00

abstract：:Complete age-related regression of mammary epithelium, often termed postmenopausal involution, is associated with decreased breast cancer risk. However, most studies have qualitatively assessed involution. We quantitatively analyzed epithelium, stroma, and adipose tissue from histologically normal breast tissue of 454...

journal_title：Human pathology

authors： Sandhu R,Chollet-Hinton L,Kirk EL,Midkiff B,Troester MA

更新日期：2016-02-01 00:00:00

abstract：:Implementation of Grade Groups (GrGrs) has been widely accepted for reporting prostate cancer grade since the 2014 International Society of Urological Pathology consensus meeting. Despite their undisputed value for risk stratification, some GrGr are, a priori, quite heterogeneous in that they contain multiple Gleason ...

journal_title：Human pathology

authors： Acosta AM,Taplin ME,Mata DA,D'Amico AV,Hirsch MS

更新日期：2020-05-01 00:00:00

abstract：:Galectins, a family of beta-galactoside-binding animal lectins, might be involved in tumor progression. In this study, the expression patterns of galectin-1 and -3 were examined immunohistochemically in intrahepatic cholangiocarcinoma (ICC), with emphasis on its development and progression as well as its histopatholog...

journal_title：Human pathology

authors： Shimonishi T,Miyazaki K,Kono N,Sabit H,Tuneyama K,Harada K,Hirabayashi J,Kasai K,Nakanuma Y

更新日期：2001-03-01 00:00:00

abstract：:Fifty-three pure mucinous carcinomas of breast were studied, with long-term follow-up evaluation (average, 15 years) for 37. The mean age of the patients was 63 years. Long-term survival (Kaplan-Meier method) was 68 per cent, excluding non-tumor-related deaths. Median survival for the patients with fatal carcinomas wa...

journal_title：Human pathology

authors： Clayton F

更新日期：1986-01-01 00:00:00

abstract：:To obtain a better understanding of steroid metabolism associated with adrenocortical malignancy we studied steroidogenesis in nine cases of adrenocortical carcinoma (six with Cushing's syndrome, two without clinically significant adrenocortical hormonal abnormalities, and one with primary aldosteronism) by analyzing ...

journal_title：Human pathology

authors： Sasano H,Suzuki T,Nagura H,Nishikawa T

更新日期：1993-04-01 00:00:00

abstract：:Mucus-filled cystic tumors of low or borderline malignant potential, well recognized in ovary and appendix, have received little attention in the lung. We present data on 11 patients, all of whom had solitary pulmonary nodules resected in which mucus was the major histologic component. Prognosis appears good; no patie...

journal_title：Human pathology

authors： Graeme-Cook F,Mark EJ

更新日期：1991-02-01 00:00:00

abstract：:Myopericytoma is a rare, histologically distinctive tumor that shows evidence of differentiation toward perivascular myoid cells. Myopericytoma is largely considered a neoplasm of skin and soft tissues, with examples of this lesion involving visceral sites being extremely limited. We present the clinical and pathologi...

journal_title：Human pathology

authors： Lau SK,Klein R,Jiang Z,Weiss LM,Chu PG

更新日期：2010-10-01 00:00:00

abstract：:We received the clinical records and pathologic material of 20 patients with biopsy proven hepatic focal nodular hyperplasia. The majority of the patients were females of child bearing age, five of whom had a history of oral use of contraceptives. In every instance focal nodular hyperplasia was an incidental finding; ...

journal_title：Human pathology

authors： Knowles DM,Wolff M

更新日期：1976-09-01 00:00:00

abstract：:Our previous investigations of transforming growth factor types beta 1 and beta 2 (TGF beta s) showed negative or positive autocrine growth regulation of gliomas in vitro. Near-diploid gliomas were inhibited by the TGF beta s, whereas a stimulatory response correlated with progressive anaplasia and karyotypic divergen...

journal_title：Human pathology

authors： Jennings MT,Kaariainen IT,Gold L,Maciunas RJ,Commers PA

更新日期：1994-05-01 00:00:00

abstract：:We report here an exceptional pattern of atypical lentiginous melanocytic proliferation within an adenoma, leading to focal lamina propria infiltration and pulmonary metastasis, which was considered as primary colonic mucosal melanoma (MM) in a Caucasian patient. Such case illustrates the diagnosis criteria required t...

journal_title：Human pathology

authors： Furudoï A,Caumont C,Dutriaux C,Cappellen D,Goussot JF,Vergier B,Merlio C,Barberis C,Merlio JP,Gros A

更新日期：2016-02-01 00:00:00

abstract：:Thoracoamniotic shunting is the treatment of choice for management of the fetus with type 1 congenital pulmonary airway malformation. Thoracoamniotic shunting has been performed to reduce life-threatening risks such as fetal hydrops. However, caution is needed because of possible complications. Here, we report that th...

journal_title：Human pathology

authors： Matsuoka K,Hayashi S,Urano F,Zhu LJ,Okita H,Sago H,Nakazawa A

更新日期：2012-09-01 00:00:00