Relationships between histology, monoclonal antibody reactivity, and prognosis in breast cancer.

Abstract:

:Infiltrating ductal carcinoma of the breast is histologically heterogeneous and may be subdivided into three main types (A, B, and C) which correlate with the likelihood of long-term survival. Examples of each type were tested against three monoclonal antibodies (H59, H71, and H72) prepared against the breast cancer cell line ZR-75-1. The reaction patterns of type B tumors were significantly different from those of types A and C with antibodies H59 and H71, but not with H72. Thus, the reactivity to these monoclonal antibodies, and presumably the antigen composition of the tumor cells, correlates with the histologic appearances and probability of long-term survival.

journal_name

Hum Pathol

journal_title

Human pathology

authors

Yuan D,Dawson PJ

doi

10.1016/s0046-8177(87)80375-1

subject

Has Abstract

pub_date

1987-11-01 00:00:00

pages

1097-100

issue

11

eissn

0046-8177

issn

1532-8392

pii

S0046-8177(87)80375-1

journal_volume

18

pub_type

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