Where will the resources for the fifth year come from?

abstract：:In the present study the clinical and pathological evolution of a reactive-like B-cell lymphoproliferative disorder with an unusually high content of T cells is described. Immunogenotypic analysis showed that the same phenotypically atypical B-cell clone, characterized by the unusual presence of an immunoglobulin (Ig)...

journal_title：Human pathology

authors： Dolcetti R,De Re V,Carbone A,De Vita S,Gloghini A,Tirelli U,Pasquotti B,Boiocchi M

更新日期：1995-03-01 00:00:00

abstract：:Retroperitoneal cysts are uncommon diseases, and benign nonneoplastic Müllerian cysts are extremely rare among the known cases. We report a case of a 35-year-old woman with a retroperitoneal Müllerian cyst with the tubal type of epithelium. The patient presented with a large (20 cm in diameter), palpable abdominal mas...

journal_title：Human pathology

authors： Konishi E,Nakashima Y,Iwasaki T

更新日期：2003-02-01 00:00:00

abstract：:Except for post-transfusion hepatitis (PTH), the transmission of disease by blood transfusion appears to be very limited. There are only a few case reports documenting the transmission of malaria and other parasitic diseases, syphilis, or bacterial infections. The ability to eradicate PTH will depend on the developmen...

journal_title：Human pathology

authors： Kahn RA

更新日期：1983-03-01 00:00:00

abstract：:A 15 year old girl presented with a painful desquamative rash, fever, and profound hypotension. Despite antimicrobial therapy and intensive supportive measures, she died 80 hours after admission. The premortem skin biopsy and autopsy findings, which included subepidermal edema and blister formation, subacute vasculiti...

journal_title：Human pathology

authors： Abdul-Karim FW,Lederman MM,Carter JR,Hewlett EL,Newman AJ,Greene BM

更新日期：1981-01-01 00:00:00

abstract：:Although the histologic appearance of pure testicular teratomas (PTTs) is similar in children and adults, the prognosis is dramatically different. Prepubertal PTTs are rare, with a benign clinical course, whereas the adult cases typically have malignant outcomes. Chromosome 12p abnormalities are seen in most adult tes...

journal_title：Human pathology

authors： Cornejo KM,Cheng L,Church A,Wang M,Jiang Z

更新日期：2016-03-01 00:00:00

abstract：:Acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) generally confers poor prognosis; however, the clinical outcome remains heterogeneous. We sought to further stratify this subentity of AML by performing a retrospective analysis of 179 adult patients with AML-MRC diagnosed at our institution. Based o...

journal_title：Human pathology

authors： Jiang G,Capo-Chichi JM,Liu A,Atenafu EG,Guo R,Tierens A,Minden MD,Chang H

更新日期：2020-10-01 00:00:00

abstract：:Although the histopathologic patterns associated with Helicobacter pylori infection have been described, details of the interaction between bacteria, epithelial cells, and inflammatory cells remain elusive. One of the limiting factors has been the lack of a staining technique that allows the simultaneous visualization...

journal_title：Human pathology

authors： Genta RM,Robason GO,Graham DY

更新日期：1994-03-01 00:00:00

abstract：:Urethral caruncle is a benign polypoid mass of the urethral meatus in primarily postmenopausal women. Although a conclusive association with malignancy, urologic disorder, or systemic disease has not been established, often the lesion carries a challenging clinical differential diagnosis that includes malignancy. Conv...

journal_title：Human pathology

authors： Conces MR,Williamson SR,Montironi R,Lopez-Beltran A,Scarpelli M,Cheng L

更新日期：2012-09-01 00:00:00

abstract：:Oral squamous cell carcinoma (OSCC) is the most common oral cancer, and major efforts is being made to identify molecular markers capable to differentiate oral potentially malignant lesions (OPMLs) with indolent course from lesions with aggressive behavior. We undertook a study to evaluate if gain of the human telomer...

journal_title：Human pathology

authors： Dorji T,Monti V,Fellegara G,Gabba S,Grazioli V,Repetti E,Marcialis C,Peluso S,Di Ruzza D,Neri F,Foschini MP

更新日期：2015-09-01 00:00:00

abstract：:Intrasinusoidal infiltration of bone marrow (BM) may accompany several malignant lymphoproliferative disorders. In small B-cell lymphomas, this pattern is considered specific for splenic marginal zone lymphoma (SMZL) when exclusive or prominent, although it may occur in other subtypes of non-Hodgkin's lymphomas (NHLs)...

journal_title：Human pathology

authors： Schenka AA,Gascoyne RD,Duchayne E,Delsol G,Brousset P

更新日期：2003-08-01 00:00:00

abstract：:δ-Like ligand 4 (DLL4), a ligand for the Notch family of receptors, forecasts the prognosis of several human malignancies. However, the expression and role of DLL4 in breast cancer remain largely unknown. In the present study, we first evaluated whether the overexpression of DLL4 could be used as an indicator of axill...

journal_title：Human pathology

authors： Xiao M,Yang S,Ning X,Huang Y

更新日期：2014-11-01 00:00:00

abstract：:Microsatellite instability (MSI) defines a specific type of genetic instability. Although consensus diagnostic criteria for MSI definition in colorectal cancer have been established, their utility in other tumor types remain to be proven. Previously we developed a mathematical model for MSI definition in colorectal ca...

journal_title：Human pathology

authors： Musulén E,Moreno V,Reyes G,Sancho FJ,Peinado MA,Esteller M,Herman JG,Combalia N,Rey M,Capellá G

更新日期：2004-03-01 00:00:00

abstract：:Two patients with systemic capillary leak syndrome (SCLS) were followed up clinically for 5 and 2 years, respectively. Muscle biopsy was performed 1 week after the end of an acute crisis in one patient, and after 3 years in the other. In both cases, muscle capillary basement membranes were extremely thick--more than 1...

journal_title：Human pathology

authors： Navarro C,García-Bragado F,Lima J,Fernández JM

更新日期：1990-03-01 00:00:00

abstract：:A 39-year-old female patient was admitted to explore chronic renal failure. Clinical history included silicone breast implants. Clinical examination was normal. Urinalysis revealed tubular proteinuria with Bence-Jones κ protein. Monoclonal immunoglobulin G κ and free monoclonal κ-light chains (LCs) were revealed by se...

journal_title：Human pathology

authors： Figueres ML,Beaume J,Vuiblet V,Rabant M,Bassilios N,Herody M,Touchard G,Noël LH

更新日期：2015-01-01 00:00:00

abstract：:Recently, the fusion gene EML4-ALK was identified in non-small cell lung carcinoma, which could be a potential therapeutic target. We investigated the prevalence of anaplastic lymphoma kinase protein expression in these tumors by immunohistochemistry and correlated the results with data from ALK molecular studies. Gen...

journal_title：Human pathology

authors： Boland JM,Erdogan S,Vasmatzis G,Yang P,Tillmans LS,Johnson MR,Wang X,Peterson LM,Halling KC,Oliveira AM,Aubry MC,Yi ES

更新日期：2009-08-01 00:00:00

abstract：:T-prolymphocytic leukemia (T-PLL) is a rare mature T-cell neoplasm characterized by proliferation of prolymphocytes. Most cases involve the T-cell leukemia-1 (TCL1) gene at 14q11.2 resulting in overexpression of TCL-1, which is helpful for distinguishing T-PLL from other T-cell neoplasms. We report a patient with T-PL...

journal_title：Human pathology

authors： Hu Z,Li S,Medeiros LJ,Sun T

更新日期：2017-07-01 00:00:00

abstract：:Two patients, 14 and 46 years of age, presented with diffuse, rapidly growing intracerebral tumors leading to death 6 1/2 and 9 1/2 months, respectively, after diagnosis. Histological examination showed sheets of moderate-sized tumor cells with clear cytoplasm and central nuclei interrupted by delicate arciform vascul...

journal_title：Human pathology

authors： Mrak RE

更新日期：1994-08-01 00:00:00

abstract：:We aimed to study the expression of phosphorylated vascular endothelial growth factor receptor 2 (pVEGFR-2), a membrane-bound tyrosine kinase receptor to vascular endothelial growth factor, in 76 cases of leukemia and nonneoplastic myeloproliferative disease and in 8 reactive bone marrows. The microvessel density (MVD...

journal_title：Human pathology

authors： Zhang Y,Pillai G,Gatter K,Blázquez C,Turley H,Pezzella F,Watt SM

更新日期：2005-07-01 00:00:00

abstract：:Overexpression of mitotic arrest deficient 2 (MAD2) and/or cell division cycle 20 (CDC20) in the spindle assembly checkpoint leads to chromosomal instability and aneuploidy. Cell-in-cell (CIC) structures are formed by the process where cancer or immune cells are internalized into adjacent host cancer cells. Here, we i...

journal_title：Human pathology

authors： Kim Y,Choi JW,Lee JH,Kim YS

更新日期：2019-03-01 00:00:00

abstract：:Dysplastic nevi are an important indicator of risk of cutaneous malignant melanoma. The study of and, particularly, international communication regarding this group of lesions have been hindered by a lack of precision in diagnosis. In an effort to broaden understanding, a panel of pathologists agreed upon a set of cri...

journal_title：Human pathology

authors： Clemente C,Cochran AJ,Elder DE,Levene A,MacKie RM,Mihm MC,Rilke F,Cascinelli N,Fitzpatrick TB,Sober AJ

更新日期：1991-04-01 00:00:00

abstract：:The surgical pathologist is often called upon to make a rapid decision about the malignant potential of a soft tissue tumor. These tumors have specific stromas that support growth and endow the tumor with unique qualities, as well as being manifestations of the phenotypic expression of tumor cells. Collagen, the major...

journal_title：Human pathology

authors： Stern R

更新日期：1981-09-01 00:00:00

abstract：:Wild type p53 plays a crucial role in maintaining genomic stability in both normal and tumor cells in vitro. When DNA damage occurs, p53 acts as a cell cycle checkpoint and induces a cellular response that aims at restoring genomic integrity. p53 may either allow the repair of damaged DNA by inducing a transient G1 ar...

journal_title：Human pathology

authors： Moll UM,Ostermeyer AG,Ahomadegbe JC,Mathieu MC,Riou G

更新日期：1995-12-01 00:00:00

abstract：:Monoclonal antibodies to somatostatin receptors 2A (SSTR2A, UMB-1) and 5 (SSTR5, UMB-4) were reported to be highly reliable for immunohistochemical detection of these receptors in neuroendocrine neoplasms. However, the standardization of either the immunohistochemical procedure and the methods of evaluation has yet to...

journal_title：Human pathology

authors： Kasajima A,Papotti M,Ito W,Brizzi MP,La Salvia A,Rapa I,Tachibana T,Yazdani S,Sasano H,Volante M

更新日期：2018-02-01 00:00:00

abstract：:The ontogeny and distribution of the epidermal growth factor (EGF) receptor and lipocortin-1, a major cellular substrate of the EGF receptor, were evaluated in a developmental series of fetal and neonatal human lungs (8 to 41 weeks' gestation and stillborn to 16 days' postnatal age). The peroxidase anti-peroxidase tec...

journal_title：Human pathology

authors： Johnson MD,Gray ME,Carpenter G,Pepinsky RB,Stahlman MT

更新日期：1990-02-01 00:00:00

abstract：:Langerhans cell histiocytosis (LCH) is a group of granulomatous disorders in which abnormal Langerhans cells proliferate as either a localized lesion in a single bone or disseminated disease involving two or more organs or systems. Because the different LCH forms exhibit significantly elevated levels of inflammatory m...

journal_title：Human pathology

authors： Murakami I,Matsushita M,Iwasaki T,Kuwamoto S,Kato M,Horie Y,Hayashi K,Imamura T,Morimoto A,Imashuku S,Gogusev J,Jaubert F,Takata K,Oka T,Yoshino T

更新日期：2014-01-01 00:00:00

abstract：:Polymer substances are commonly applied as surface coatings on endovascular catheters and vascular devices. Adverse effects related to their use have been reported, although the overall clinical significance and appropriate methods of detection of these complications have been unclear. In this analysis, we systematica...

journal_title：Human pathology

authors： Mehta RI,Mehta RI

更新日期：2016-07-01 00:00:00

abstract：:Annexin A1 (ANXA1) is a calcium- and phospholipid-binding protein and a known mediator of glucocorticoid-regulated inflammatory responses. Using a combined multiple high-throughput approach, we recently identified a reduced expression of ANXA1 in human breast cancer. The finding was confirmed at the gene level by quan...

journal_title：Human pathology

authors： Shen D,Nooraie F,Elshimali Y,Lonsberry V,He J,Bose S,Chia D,Seligson D,Chang HR,Goodglick L

更新日期：2006-12-01 00:00:00

abstract：:K homology domain containing protein overexpressed in cancer (KOC) is a member of the insulin-like growth factor (IGF) messenger RNA-binding protein family and is expressed during embryogenesis and in certain malignancies. KOC, known as L523S and IGF messenger RNA-binding protein 3, was shown to be frequently expresse...

journal_title：Human pathology

authors： Xu H,Bourne PA,Spaulding BO,Wang HL

更新日期：2007-04-01 00:00:00

abstract：:The distinction between Spitz nevus and melanoma is currently possible, applying a set of definite histological criteria. However, in certain lesions deviating from the stereotypical morphology of classic Spitz nevi ("atypical Spitz tumors"), the differentiation between benign and malignant cases appears problematic b...

journal_title：Human pathology

authors： Urso C,Borgognoni L,Saieva C,Ferrara G,Tinacci G,Begliomini B,Reali UM

更新日期：2006-07-01 00:00:00

abstract：:Immunofluorescent staining of tissue from a lung tumor detected 12 years after excision of a primary malignant melanoma of the skin was negative for prekeratin and positive for vimentin, indicating that the tumor was not epithelial in origin and excluding carcinoma from the differential diagnosis. Complementary conven...

journal_title：Human pathology

authors： Huszar M,Halkin H,Herczeg E,Bubis J,Geiger B

更新日期：1983-11-01 00:00:00