Muscle biopsy findings in systemic capillary leak syndrome.

Abstract:

:Two patients with systemic capillary leak syndrome (SCLS) were followed up clinically for 5 and 2 years, respectively. Muscle biopsy was performed 1 week after the end of an acute crisis in one patient, and after 3 years in the other. In both cases, muscle capillary basement membranes were extremely thick--more than 15 times thicker than normal. Capillary basement membrane enlargement appears to be a permanent lesion, probably limited to muscle vessels. This finding has not been previously reported in SCLS, and would appear to indicate a relationship with the pathogenesis and severity of the crisis.

journal_name

Hum Pathol

journal_title

Human pathology

authors

Navarro C,García-Bragado F,Lima J,Fernández JM

doi

10.1016/0046-8177(90)90230-3

subject

Has Abstract

pub_date

1990-03-01 00:00:00

pages

297-301

issue

3

eissn

0046-8177

issn

1532-8392

pii

0046-8177(90)90230-3

journal_volume

21

pub_type

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