Abstract:
:Two patients with systemic capillary leak syndrome (SCLS) were followed up clinically for 5 and 2 years, respectively. Muscle biopsy was performed 1 week after the end of an acute crisis in one patient, and after 3 years in the other. In both cases, muscle capillary basement membranes were extremely thick--more than 15 times thicker than normal. Capillary basement membrane enlargement appears to be a permanent lesion, probably limited to muscle vessels. This finding has not been previously reported in SCLS, and would appear to indicate a relationship with the pathogenesis and severity of the crisis.
journal_name
Hum Patholjournal_title
Human pathologyauthors
Navarro C,García-Bragado F,Lima J,Fernández JMdoi
10.1016/0046-8177(90)90230-3subject
Has Abstractpub_date
1990-03-01 00:00:00pages
297-301issue
3eissn
0046-8177issn
1532-8392pii
0046-8177(90)90230-3journal_volume
21pub_type
杂志文章相关文献
HUMAN PATHOLOGY文献大全abstract::Galectins, a family of beta-galactoside-binding animal lectins, might be involved in tumor progression. In this study, the expression patterns of galectin-1 and -3 were examined immunohistochemically in intrahepatic cholangiocarcinoma (ICC), with emphasis on its development and progression as well as its histopatholog...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1053/hupa.2001.22767
更新日期:2001-03-01 00:00:00
abstract::Encapsulated thyroid tumors of follicular cell origin with high-grade features (EFHG) are unusual neoplasms. In current classification schemes, they are called atypical adenomas or follicular, papillary, or poorly differentiated carcinoma. When noninvasive, EFHG create a major therapeutic/diagnostic dilemma stemming f...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2009.08.011
更新日期:2010-02-01 00:00:00
abstract::Idiopathic hypereosinophilic syndrome (HES) consists of a prolonged state of eosinophilia of unknown origin with organ involvement. We describe the case of a patient who developed fatal eosinophilic myocarditis. A 23-year-old woman with an 8-month history of eosinophilia presented with symptoms of myocarditis. Histolo...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2004.05.008
更新日期:2004-09-01 00:00:00
abstract::Multicentric Castleman disease (MCD) is a systemic inflammatory disease potentially caused by an increase in the serum interleukin-6 (IL-6) level. Idiopathic MCD (iMCD) is histopathologically classified into three types: plasmacytic (PC), mixed, and hypervascular (hyperV) types. Recently, a unique clinical phenotype w...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2018.04.001
更新日期:2018-07-01 00:00:00
abstract::We have begun a systematic study of human papillomavirus (HPV) infection in colposcopically and/or morphologically normal epithelium of the uterine cervix. Paired biopsies were taken from the lesions (cervical intraepithelial neoplasia [CIN], condyloma, invasive carcinoma) and from the normal-appearing adjacent epithe...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/0046-8177(89)90039-7
更新日期:1989-04-01 00:00:00
abstract::To elucidate the pathogenesis of aging changes and their relation to age associated calcification, a morphological study of 27 human aortic valves was carried out. Nine valves were obtained from immediate autopsies and 18 valves from routine autopsies done within four hours after death. Calcium deposition was present ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(76)80005-6
更新日期:1976-01-01 00:00:00
abstract::The intraoperative diagnosis of pulmonary neuroendocrine tumors can be difficult. Frozen section diagnosis was requested on 87 neuroendocrine tumors including 58 typical carcinoids, 8 atypical carcinoids, 18 large cell neuroendocrine carcinomas, and 3 small cell carcinomas from 2405 patients that underwent frozen sect...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2008.07.017
更新日期:2009-01-01 00:00:00
abstract::Limitations in obtaining surgically resected or biopsy samples of small cell lung cancer (SCLC) tumors make comprehensive biological analyses difficult. The loss of thyroid transcription factor 1 (TTF-1) has been associated with the aggressive behavior of non-small cell lung cancer; however, clinicopathological featur...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2018.05.009
更新日期:2018-09-01 00:00:00
abstract::Hydatidiform moles are classified as partial or complete by histologic criteria (Am J Obstet Gynecol 131:665-671, 1978 and Am J Obstet Gynecol 132:20-27, 1978). While persistent gestational trophoblastic tumors follow both types, there remains controversy as to whether the malignant extreme of gestational trophoblasti...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/0046-8177(92)90096-l
更新日期:1992-04-01 00:00:00
abstract::Hepatitis C virus (HCV) infection may be complicated by non-Hodgkin's lymphoma through yet unknown pathogenetic mechanisms. We describe the case of a patient with HCV-related cirrhosis who developed a primary effusion lymphoma (PEL) of Burkitt's type confined to the peritoneal cavity, in the absence of immunodeficienc...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(97)90287-2
更新日期:1997-01-01 00:00:00
abstract::Clinicopathological studies of 181 patients with liver cirrhosis undergoing autopsy in the pathology department of a municipal hospital between 1973 and 1976 are reported. The main etiological types were alcoholic (25.4 per cent), HBsAg positive (14.9 per cent), and cryptogenic cirrhosis (54.7 per cent). Four patients...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(81)80082-2
更新日期:1981-09-01 00:00:00
abstract::The Mix1 homeobox-like (MIXL1) gene encodes a paired class homeobox transcription factor that is involved in embryogenesis. Previous studies have shown that the MIXL1 gene product is expressed in B- and T-cell progenitors of normal bone marrow and, in some cell lines derived from hematopoietic neoplasms. The status of...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2006.09.020
更新日期:2007-03-01 00:00:00
abstract::To assess the proliferative activity of renal cell carcinoma (RCC-A) in patients with acquired cystic disease of the kidney (ACDK) after long-term hemodialysis, we analyzed cell cycle, DNA ploidy, and S-phase fraction by flow cytometry (FCM) and proliferating cell nuclear antigen (PCNA) labeling index by immunohistoch...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1053/hupa.2002.30188
更新日期:2002-02-01 00:00:00
abstract::Cellular crescents are typically inflammatory and associated with rapidly progressive glomerulonephritis. Their pathogenesis involves glomerular basement membrane rupture due to circulating or intrinsic factors. Crescents associated with diabetic glomerulosclerosis are rarely reported. Furthermore, the nature of cells...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2013.10.030
更新日期:2014-03-01 00:00:00
abstract::The mucin profile of 24 endoscopic biopsies of heterotopic gastric mucosa (HGM) of the upper esophagus in adults and a control group of ten cases of Meckel's diverticula containing heterotopic gastric mucosa were studied with two combined histochemical methods: alcian blue pH 2.5/PAS and high iron diamine/alcian blue ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(88)80285-5
更新日期:1988-11-01 00:00:00
abstract::Seven cases in which interstitial fibrosis developed in patients who had acute interstitial pneumonia were studied ultrastructurally to elucidate the pathogenesis of the interstitial thickening seen by light microscopy. Interstitial fibrosis is generally thought to result from fibroblast proliferation and collagen dep...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(85)80279-3
更新日期:1985-10-01 00:00:00
abstract::After endoscopic resection of early gastric cancer (EGC), it is imperative to accurately determine whether follow-up surgery is indicated, since this technique is used as a first line of treatment. Herein, we developed a scoring system to indicate the risk of lymph node metastasis in submucosal EGC (smEGC), and presen...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2013.07.037
更新日期:2013-12-01 00:00:00
abstract::Recent polymerase chain reaction (PCR)-based studies focused on the detection of immunoglobulin heavy chain gene (IgH) rearrangements have suggested that clonal populations may be amplified more easily from certain categories of B-cell neoplasia than others and that primer makeup can be a critical factor in successful...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/0046-8177(94)90084-1
更新日期:1994-12-01 00:00:00
abstract::Fluorescent (FISH) and chromogenic (CISH) in situ hybridization have recently become part of the diagnostic armamentarium of breast pathologists. HER2 gene testing by FISH and/or CISH has become an integral part of the diagnostic workup for patients with breast cancer. In this era of high throughput technologies, thes...
journal_title:Human pathology
pub_type: 杂志文章,评审
doi:10.1016/j.humpath.2007.04.011
更新日期:2007-08-01 00:00:00
abstract::Basal cell hyperplasia (BCH) is an uncommon proliferative lesion of the prostate gland. We studied ten cases of BCH, one case of an unusual adenoid basal cell tumor (ABT), and one case of a prostatic adenoid cystic carcinoma (ACC), using a panel of antibodies to define the histogenesis of these lesions. Monoclonal ant...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(88)80235-1
更新日期:1988-12-01 00:00:00
abstract::Complete age-related regression of mammary epithelium, often termed postmenopausal involution, is associated with decreased breast cancer risk. However, most studies have qualitatively assessed involution. We quantitatively analyzed epithelium, stroma, and adipose tissue from histologically normal breast tissue of 454...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2015.09.031
更新日期:2016-02-01 00:00:00
abstract::Plasma cells are the hallmark of chronic endometritis but are not specific for upper tract infection. Plasma cells have also been noted in hormonally mediated endometrial disorders in association with gland architectural changes ("disordered proliferative" and "anovulatory" patterns), and stromal breakdown. We reviewe...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2006.09.002
更新日期:2007-04-01 00:00:00
abstract::Automatic quantification of cardinal histologic features of nonalcoholic fatty liver disease (NAFLD) may reduce human variability and allow continuous rather than semiquantitative assessment of injury. We recently developed an automated classifier that can detect and quantify macrosteatosis with greater than or equal ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2015.01.019
更新日期:2015-05-01 00:00:00
abstract::Hepatocyte growth factor has been identified as a lymphangiogenic factor in experimental animal models. However, the correlation between hepatocyte growth factor or c-Met expression and lymphangiogenesis in human spontaneous tumors has been rarely reported, and the distribution pattern of c-Met on tumor-related lympha...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2010.03.012
更新日期:2011-10-01 00:00:00
abstract::Retroperitoneal cysts are uncommon diseases, and benign nonneoplastic Müllerian cysts are extremely rare among the known cases. We report a case of a 35-year-old woman with a retroperitoneal Müllerian cyst with the tubal type of epithelium. The patient presented with a large (20 cm in diameter), palpable abdominal mas...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1053/hupa.2003.12
更新日期:2003-02-01 00:00:00
abstract::Fabry disease is an X-linked lysosomal storage disease caused by deficiency of α-galactosidase A, resulting in the accumulation of globotriaosylceramide. Many women experience symptoms, but the understanding of placental and fetal aspects of the disease is limited. We report the pregnancy outcome in and placental path...
journal_title:Human pathology
pub_type: 杂志文章,评审
doi:10.1016/j.humpath.2011.07.020
更新日期:2012-04-01 00:00:00
abstract::We describe a case of a complete hydatidiform mole with a coexistent embryo. A 19-year-old Hispanic woman presented with an intrauterine pregnancy at 7 weeks gestational age. An ultrasound evaluation at that time showed a gestational sac and fetal heart activity was observed. Four weeks later, subsequent ultrasound st...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(96)90406-2
更新日期:1996-07-01 00:00:00
abstract::The histologic findings in lymph nodes were used to identify eight patients, who are not in a high-risk group, with human immunodeficiency virus (HIV) infection. In order to determine the specificity of these findings, the histologic and clinical findings in these patients were compared with the histologic and clinica...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(88)80269-7
更新日期:1988-07-01 00:00:00
abstract::The proliferation marker mitotic activity index is the strongest prognostic indicator in lymph node-negative breast cancer. The World Health Organization (WHO) 2003-defined procedure for determining WHO-mitotic activity index is often replaced by a quick scan mitotic impression. We evaluated the prognostic consequence...
journal_title:Human pathology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.humpath.2007.08.016
更新日期:2008-04-01 00:00:00
abstract::Paraffin-embedded sections of 99 human adrenal and extraadrenal paragangliomas were analyzed by the indirect immunoperoxidase technique for the presence of neuron-specific enolase (NSE) and 10 neuropeptides. Each showed diffuse staining for NSE. Most tumors were positive for [Leu5]-enkephalin (76 per cent), [Met5]-enk...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(88)80314-9
更新日期:1988-01-01 00:00:00