Primary effusion Burkitt's lymphoma with t(8;22) in a patient with hepatitis C virus-related cirrhosis.

abstract：:Tumor necrosis factor alpha (TNF alpha) and interleukin-6 (IL-6) antigenic sites were shown within the resident glomerular mesangial cells of lupus nephritis patients applying the colloidal gold immunocytochemical approach at the electron microscopic level. Using specific polyclonal antibodies against human recombinan...

journal_title：Human pathology

authors： Malide D,Russo P,Bendayan M

更新日期：1995-05-01 00:00:00

abstract：:The evolution of sequential histological changes from normal cells through invasive cancer affords the cancer biologist the opportunity to identify separate molecular steps involved in cancer progression. As one studies the development of human carcinoma, it becomes apparent that multiple genetic alterations affecting...

journal_title：Human pathology

authors： Stemmermann G,Heffelfinger SC,Noffsinger A,Hui YZ,Miller MA,Fenoglio-Preiser CM

更新日期：1994-10-01 00:00:00

abstract：:In the past decade most studies of coronary arterial aneurysms have been clinical; few have focused on morphology and etiopathogenesis. The subjects of the present autopsy study were 52 patients, 5 months to 80 years of age, with coronary arterial aneurysms. Patients were divided into two groups: 38 with atherosclerot...

journal_title：Human pathology

authors： Virmani R,Robinowitz M,Atkinson JB,Forman MB,Silver MD,McAllister HA

更新日期：1986-06-01 00:00:00

abstract：:The histogenesis of colloid cysts (CCs) of the third ventricle has been a subject of controversy. We examined, using immunohistochemical techniques, four CCs for the presence of cytokeratins (CKs), glutathione S-transferase isoenzymes (GST-pi, GST-mu), and glial fibrillary acidic protein. Antibodies to both low molecu...

journal_title：Human pathology

authors： Tsuchida T,Hruban RH,Carson BS,Phillips PC

更新日期：1992-07-01 00:00:00

abstract：:Hepatic involvement by a T-cell neoplasm is rare and often challenging to diagnose in liver biopsies. We collected 40 cases of T-cell neoplasms diagnosed in the liver from five large academic institutions to assess the clinicopathologic features. The patients included 11 women and 29 men, with a median age of 54 (rang...

journal_title：Human pathology

authors： Li P,Zhang D,Zhou J,Li P,Shen Y,Pan Z,Evans AG,Liao X

更新日期：2020-12-01 00:00:00

abstract：:A case of a primary carcinoid islet cell tumor of the duodenum is reported, demonstrated by histochemistry, electron microscopy, and immunofluorescence to be composed of alpha cells containing glucagon-like material. The patient was found on admission to have hyperglycemia and a diffuse skin rash. Primary duodenal glu...

journal_title：Human pathology

authors： Roggli VL,Judge DM,McGavran MH

更新日期：1979-05-01 00:00:00

abstract：:Esophageal cancer is one of the most fatal cancers worldwide and is characterized by great variation in rates among different populations. Linxian, a county in Henan Province, located in north-central China, has one of the highest rates of esophageal squamous cell carcinoma in the world. Most squamous cell carcinomas ...

journal_title：Human pathology

authors： Roth MJ,Guo-Qing W,Lewin KJ,Ning L,Dawsey SM,Wesley MN,Giffen C,Yong-Qiang X,Maher MM,Taylor PR

更新日期：1998-11-01 00:00:00

abstract：:Anaplastic meningiomas (MIIIs) and meningeal hemangiopericytomas (HPCs) display significant morphologic and immunohistochemical overlap, including occasional cases of otherwise classic HPC with focal epithelial membrane antigen (EMA) positivity. The availability of several new biomarkers prompted us to examine the pot...

journal_title：Human pathology

authors： Rajaram V,Brat DJ,Perry A

更新日期：2004-11-01 00:00:00

abstract：:Nonsteroidal anti-inflammatory drug (NSAID) use is a common cause of peptic ulcer. This study investigated the nature, frequency, and topographic distribution of histological abnormalities of the gastric mucosa associated with chronic NSAID use. A set of 3 to 11 mapped gastric biopsy specimens were obtained from 108 c...

journal_title：Human pathology

authors： El-Zimaity HM,Genta RM,Graham DY

更新日期：1996-12-01 00:00:00

abstract：:We received the clinical records and pathologic material of 20 patients with biopsy proven hepatic focal nodular hyperplasia. The majority of the patients were females of child bearing age, five of whom had a history of oral use of contraceptives. In every instance focal nodular hyperplasia was an incidental finding; ...

journal_title：Human pathology

authors： Knowles DM,Wolff M

更新日期：1976-09-01 00:00:00

abstract：:This report describes the biopsy findings in four of 30 patients treated with cadaver osteochondral shell allografts for osteoarthritis in the knee. This study demonstrates that graft cartilage cells can survive in excess of 25 months, and that host bone can completely replace graft bone by creeping substitution. An i...

journal_title：Human pathology

authors： Pritzker KP,Gross AE,Langer F,Luk SC,Houpt JB

更新日期：1977-11-01 00:00:00

abstract：:Although adipophilin has been reported to be a sensitive marker for sebaceous carcinoma, others have noted its expression in squamous cell carcinoma and a variety of noncutaneous tumors, suggesting that lipid droplet accumulation is a frequent feature of neoplastic cells. We investigated the expression of adipophilin ...

journal_title：Human pathology

authors： Boussahmain C,Mochel MC,Hoang MP

更新日期：2013-09-01 00:00:00

abstract：:Langerhans' cell histiocytosis (LCH) is a proliferative histiocytic disorder of unknown etiology. We previously reported that Epstein-Barr virus (EBV) infects and proliferates in macrophages, and investigated the possibility that EBV exhibits etiologic effects in LCH. To detect EBV expression, paraffin sections from 1...

journal_title：Human pathology

authors： Shimakage M,Sasagawa T,Kimura M,Shimakage T,Seto S,Kodama K,Sakamoto H

更新日期：2004-07-01 00:00:00

abstract：:We report 13 cases of unique polypoid urothelial tumors with inverted growth pattern (PUTIPs) occurring in the proximal ureter and renal pelvis. We describe their morphologic features and further characterize them in regard to TERT promoter mutation status and microsatellite instability. Thirteen cases were identified...

journal_title：Human pathology

authors： Wobker SE,Zhong M,Epstein JI

更新日期：2017-01-01 00:00:00

abstract：:The expression/activation of epidermal growth factor receptor (EGFR) and the correlation with the phosphorylation status of downstream modulator proteins, Akt, mammalian target of rapamycin (mTOR), p70S6-kinase (S6K), ribosomal protein S6 (rS6), and eukaryotic initiation factor 4E-binding protein 1 (4E-BP1), were anal...

journal_title：Human pathology

authors： Dobashi Y,Suzuki S,Kimura M,Matsubara H,Tsubochi H,Imoto I,Ooi A

更新日期：2011-02-01 00:00:00

abstract：:Perineural invasion is a histologic feature usually diagnostic of invasion in malignancies. In the breast, however, it has been associated with benign lesions such as sclerosing adenosis (SA), complex sclerosing lesion/radial scar (CSL/RS), and ductal carcinoma in situ (DCIS). This article describes perineural invasio...

journal_title：Human pathology

authors： Gobbi H,Jensen RA,Simpson JF,Olson SJ,Page DL

更新日期：2001-08-01 00:00:00

abstract：:Cell adhesion molecule expression has been linked to disease outcome in prostatic adenocarcinomas (PACs). We evaluated the coordinated expression of catenin-related proteins, E-cadherin, N-cadherin, and CD44s in PACs. Archival sections from 112 PACs were immunostained by an automated method (Ventana Medical Systems, T...

journal_title：Human pathology

authors： Kallakury BV,Sheehan CE,Ross JS

更新日期：2001-08-01 00:00:00

abstract：:It has been proposed that an epithelial injury may be one of the multiple primary events in the pathogenesis of idiopathic pulmonary fibrosis (IPF). The aim of this study was to characterize the tight junction and adherens junction proteins in normal human lung, IPF, cryptogenic organizing pneumonia, and asbestosis. W...

journal_title：Human pathology

authors： Lappi-Blanco E,Lehtonen ST,Sormunen R,Merikallio HM,Soini Y,Kaarteenaho RL

更新日期：2013-05-01 00:00:00

abstract：:In a review of pediatric autopsies from 1951 to 1985, we identified 40 cases in which pancreatitis was diagnosed pathologically. Twenty-six of these patients were under 4 years of age, and the male-to-female ratio was 1.5. Six groups of patients were identified: 10 with hepatobiliary disease, including 9 with biliary ...

journal_title：Human pathology

authors： Nguyen T,Abramowsky C,Ashenburg C,Rothstein F

更新日期：1988-03-01 00:00:00

abstract：:Most failures of bioprosthetic heart valves in children are due to stenosis secondary to thrombus, calcific deposits, or tissue ingrowth. Valve failures due to regurgitation typically involve cuspal detachment, tears, or perforations. We present four cases of prosthetic valve regurgitation in children caused by cuspal...

journal_title：Human pathology

authors： Murphy SK,Rogler WC,Fleming WH,McManus BM

更新日期：1988-02-01 00:00:00

abstract：:A 48-year-old man with a history of recurrent urolithiasis and chronic renal failure underwent a nephrectomy for a renal mass. At surgery the mass proved to be a calculus impacted in a dilated calyx. Gross examination of the kidney revealed chalky white deposits in the deep medulla and papillary tips. Histologic exami...

journal_title：Human pathology

authors： Gelb AB,Fye KH,Tischfield JA,Sahota AS,Sparks JW,Hancock DC,Sibley RK

更新日期：1992-09-01 00:00:00

abstract：:Papillary carcinoma of the breast is a variant of predominantly intraductal carcinoma characterized by a papillary growth pattern with fibrovascular support. Loss of heterozygosity (LOH) was evaluated at multiple chromosomal loci (including loci reported to show frequent genetic alterations in breast cancer) to determ...

journal_title：Human pathology

authors： Lininger RA,Park WS,Man YG,Pham T,MacGrogan G,Zhuang Z,Tavassoli FA

更新日期：1998-10-01 00:00:00

abstract：:To achieve real-time connectivity between its 8 hopital-based laboratories, Veterans Integrated Service Network (VISN) 12, headquartered in Chicago, IL, has implemented a hybrid dynamic store-and-forward (HDSF) telepathology network that extends across portions of 3 states. The majority of diagnostic telepathology fun...

journal_title：Human pathology

authors： Dunn BE,Choi H,Almagro UA,Recla DL

更新日期：2001-12-01 00:00:00

abstract：:Pleomorphic adenomas of the breast (PAB) are uncommon tumors. We studied the clinicopathologic features of 10 cases of PAB, seven of which were assessed immunohistochemically. Nine patients were women, with a median age at diagnosis of 65 years. Eight patients presented with a palpable mass; two had a nipple discharge...

journal_title：Human pathology

authors： Diaz NM,McDivitt RW,Wick MR

更新日期：1991-12-01 00:00:00

abstract：:Clinicopathologic records and neuropathologic tissues of 109 patients who underwent necropsy after treatment with bone marrow transplantation (BMT) were examined. Underlying disorders included leukemia (70), aplastic anemia (25), solid tumors (7), lymphoma (5), Hodgkin's disease (1) and Wiskott-Aldrich syndrome (1). T...

journal_title：Human pathology

authors： Mohrmann RL,Mah V,Vinters HV

更新日期：1990-06-01 00:00:00

abstract：:To better represent the Gleason score of radical prostatectomy, the International Society of Urologic Pathologists Consensus Committee recommends assigning individual Gleason scores to prostate cancer cores submitted in separate containers and/or multiple cores in the same container with site identifiers. However, sce...

journal_title：Human pathology

authors： Kunju LP,Daignault S,Wei JT,Shah RB

更新日期：2009-04-01 00:00:00

abstract：:Insulin-like growth factor II messenger RNA (mRNA)-binding protein 3 (IMP3) is an oncofetal protein that promotes tumor progression and metastasis in a number of malignancies. However, the clinical significance of IMP3 expression in squamous cell carcinoma (SCC) of the uterine cervix is unclear. In this study, the cor...

journal_title：Human pathology

authors： Wei Q,Yan J,Fu B,Liu J,Zhong L,Yang Q,Zhao T

更新日期：2014-11-01 00:00:00

abstract：:We describe a method for the immunocytochemical assessment of estrogen receptor (ER) status on routinely processed, formalin-fixed tissue using a recently developed commercially available monoclonal antibody (Dako 1D5) with a microwave antigen retrieval technique. A series of 90 cases of human breast carcinoma was ana...

journal_title：Human pathology

authors： Goulding H,Pinder S,Cannon P,Pearson D,Nicholson R,Snead D,Bell J,Elston CW,Robertson JF,Blamey RW

更新日期：1995-03-01 00:00:00

abstract：:Breast cancer is one of the common malignant diseases among women in Japan as well as in western countries, and its incidence continues to increase. Normal mammary duct epithelial cells exhibit a well-organized apicobasal polarity, which forms the basis for their specific structure and function. Although the loss of e...

journal_title：Human pathology

authors： Kojima Y,Akimoto K,Nagashima Y,Ishiguro H,Shirai S,Chishima T,Ichikawa Y,Ishikawa T,Sasaki T,Kubota Y,Inayama Y,Aoki I,Ohno S,Shimada H

更新日期：2008-06-01 00:00:00

abstract：:Basal cells of benign prostate glands are typically p63 positive, whereas malignant glands are usually p63 negative. A rare subset of prostatic adenocarcinoma (PCa) demonstrates aberrant diffuse p63 expression but is negative for high-molecular-weight cytokeratin. Strong p63 staining of the tumor cells can obscure the...

journal_title：Human pathology

authors： Uchida K,Ross H,Lotan T,Pignon JC,Signoretti S,Epstein JI,Illei PB

更新日期：2015-03-01 00:00:00