Renal insufficiency secondary to 2,8-dihydroxyadenine urolithiasis.

abstract：:We report 13 cases of unique polypoid urothelial tumors with inverted growth pattern (PUTIPs) occurring in the proximal ureter and renal pelvis. We describe their morphologic features and further characterize them in regard to TERT promoter mutation status and microsatellite instability. Thirteen cases were identified...

journal_title：Human pathology

authors： Wobker SE,Zhong M,Epstein JI

更新日期：2017-01-01 00:00:00

abstract：:In 2012, the lower anogenital squamous terminology (LAST) project introduced new nomenclature for human papillomavirus-related squamous lesions of the lower genital tract: low-grade and high-grade squamous intraepithelial lesion (LSIL and HSIL). Biomarker p16(INK4a) immunohistochemistry (IHC) was also recommended to a...

journal_title：Human pathology

authors： Clark JL,Lu D,Kalir T,Liu Y

更新日期：2016-09-01 00:00:00

abstract：:Ovarian ependymomas are rare glial neoplasms that typically occur in women on their third to fourth decades of life. They are histologically similar to ependymomas of the central nervous system but may have a broader immunophenotype. We describe a 27-year-old woman who presented to the emergency department with a 3-we...

journal_title：Human pathology

authors： Lopez LV,Bhattacharyya S,Carlsen ED,Bartlett D,Rao UNM

更新日期：2019-01-01 00:00:00

abstract：:To examine the hypothesis that malpositions of cardiac ventricles could be explained by altered development of the interventricular septum, we studied hearts from the Johns Hopkins Hospital autopsy files with double inlet left ventricle (16 cases) or corrected transposition (nine cases). In double inlet left ventricle...

journal_title：Human pathology

authors： Hutchins GM,Meredith MA,Moore GW

更新日期：1981-03-01 00:00:00

abstract：:Heterotopic pancreatic parenchyma recapitulates the normal pancreas in extrapancreatic locations and, on rare occasions, can even give rise to pancreatic adenocarcinoma. The genetic signatures of pancreatic adenocarcinoma and its precursor lesions are well characterized. We explored the genetic alterations in precurso...

journal_title：Human pathology

authors： Ma C,Gocke CD,Hruban RH,Belchis DA

更新日期：2016-02-01 00:00:00

abstract：:We examined the effect of lateral spatial resolution and reader specialty on the accuracy of detection of breast cancer. The motivation for this pilot study was the need to acquire and display very large data sets in whole-specimen 3D digital breast histopathology imaging. The ultimate goal is to determine the minimum...

journal_title：Human pathology

authors： Clarke GM,Zubovits JT,Katic M,Peressotti C,Yaffe MJ

更新日期：2007-12-01 00:00:00

abstract：:Telomerase is a ribonucleoprotein that consists of a RNA component for synthesizing telomeric DNA repeats onto chromosome ends, so that telomere length can be maintained; telomerase activation in general signifies immortalization of cells. Because the telomerase activity of only a few cases of nonastrocytic gliomas an...

journal_title：Human pathology

authors： Chong EY,Lam PY,Poon WS,Ng HK

更新日期：1998-06-01 00:00:00

abstract：:Extratubal secondary trophoblastic implants (ESTI) are a rare complication of conservative laparoscopic procedures for tubal ectopic pregnancies. These implants present with persistent beta-hCG titers postoperatively and are probably the result of disruption of the ectopic pregnancy at salpingostomy or morcellation of...

journal_title：Human pathology

authors： Doss BJ,Jacques SM,Qureshi F,Ramirez NC,Lawrence WD

更新日期：1998-02-01 00:00:00

abstract：:Malignant peripheral nerve sheath tumor is a malignant tumor showing nerve sheath differentiation. Approximately one-half of malignant peripheral nerve sheath tumors arise from a benign peripheral nerve sheath tumor, which is commonly a neurofibroma in patients with neurofibromatosis type 1. Malignant peripheral nerve...

journal_title：Human pathology

authors： Endo M,Yamamoto H,Harimaya K,Kohashi K,Ishii T,Setsu N,Iwamoto Y,Oda Y

更新日期：2013-12-01 00:00:00

abstract：:Idiopathic hypereosinophilic syndrome (HES) consists of a prolonged state of eosinophilia of unknown origin with organ involvement. We describe the case of a patient who developed fatal eosinophilic myocarditis. A 23-year-old woman with an 8-month history of eosinophilia presented with symptoms of myocarditis. Histolo...

journal_title：Human pathology

authors： Corradi D,Vaglio A,Maestri R,Legname V,Leonardi G,Bartoloni G,Buzio C

更新日期：2004-09-01 00:00:00

abstract：:Esophageal and colorectal adenocarcinomas overexpress Fas ligand (FasL), which can protect them from immune surveillance. The aim of this work was to determine whether FasL expression, and therefore FasL-dependent immune evasion, occurs early during malignant transformation in Barrett's metaplasia (BM) of the esophagu...

journal_title：Human pathology

authors： Younes M,Schwartz MR,Finnie D,Younes A

更新日期：1999-11-01 00:00:00

abstract：:The molecular pathology of 20 lymphomas, which presented as testicular masses in patients with no evidence of previous lymphoma, was analyzed. These lymphomas occurred in men with a median age of 69 years (range, 37 to 87 years). Nine of the 14 patients with follow-up died of lymphoma (median survival, 12 months). All...

journal_title：Human pathology

authors： Hyland J,Lasota J,Jasinski M,Petersen RO,Nordling S,Miettinen M

更新日期：1998-11-01 00:00:00

abstract：:Hypertrophic cardiomyopathy phenotype is shared by heterogeneous entities. The purpose of the study was to evaluate the diagnostic role of left ventricular endomyocardial biopsy. One hundred fifty-one consecutive patients with unexplained left ventricular hypertrophy and normal/elevated QRS voltages or left bundle-bra...

journal_title：Human pathology

authors： Frustaci A,Russo MA,Chimenti C

更新日期：2013-01-01 00:00:00

abstract：:Fifty-three surgically resected small cell carcinomas of the lung were studied morphometrically, electron microscopically, immunohistochemically, and in terms of possible site of origin. Four subtypes of small cell carcinomas were identified: oat cell carcinoma (OAT), small cell carcinoma of the intermediate cell type...

journal_title：Human pathology

authors： Nomori H,Shimosato Y,Kodama T,Morinaga S,Nakajima T,Watanabe S

更新日期：1986-06-01 00:00:00

abstract：:Increasing differentiation in the human endometrium is associated with an apparent decrease in intercellular contacts between endometrial stromal cells ...

journal_title：Human pathology

authors： Parmley TH,Roberts DK,Emsa NJ,Horbelt DV

更新日期：1990-10-01 00:00:00

abstract：:A case of thymoma with associated opportunistic infections, CD4/CD8 T-lymphocyte imbalance, low CD4-positive T-lymphocyte counts and Kaposi's sarcoma (KS) without HIV infection is reported. Cytomegalovirus inclusions were identified in the nuclei of some KS spindle and endothelial cells. It is known that KS has a high...

journal_title：Human pathology

authors： Moysset I,Lloreta J,Miguel A,Vadell C,Ribalta T,Estrach T,Serrano S

更新日期：1997-10-01 00:00:00

abstract：:The intraoperative diagnosis of pulmonary neuroendocrine tumors can be difficult. Frozen section diagnosis was requested on 87 neuroendocrine tumors including 58 typical carcinoids, 8 atypical carcinoids, 18 large cell neuroendocrine carcinomas, and 3 small cell carcinomas from 2405 patients that underwent frozen sect...

journal_title：Human pathology

authors： Gupta R,Dastane A,McKenna RJ Jr,Marchevsky AM

更新日期：2009-01-01 00:00:00

abstract：:Although the Revised European-American Lymphoma Classification does not utilize the term monocytoid B-cell Lymphoma, there are numerous reasons to support its use in classifying lymphomas of so-called marginal zone B-cell type that contain a distinct population of malignant monocytoid B-cells. In addition, there are o...

journal_title：Human pathology

authors： Nathwani BN,Hernandez AM,Deol I,Taylor CR

更新日期：1997-01-01 00:00:00

abstract：:Molecular apocrine breast cancer (MABC) is a molecular subtype with a poor prognosis, and there is urgent need to find new therapeutic targets. Epidermal growth factor receptor (EGFR) plays an important part in regulating the biological behavior of tumor cells, and EGFR-targeted drugs have already been used in therapy...

journal_title：Human pathology

authors： Liu X,Feng C,Liu J,Liu J,Li C,Xu C,Niu Y

更新日期：2018-07-01 00:00:00

abstract：:The differential diagnosis of glandular lesions of the bladder/urinary tract can be challenging because of significant morphologic and immunohistochemical overlap between primary lesions and metastasis/direct extension from adjacent organs. Special AT-rich sequence-binding protein 2 (SATB2), encoded on chromosome 2q32...

journal_title：Human pathology

authors： Giannico GA,Gown AM,Epstein JI,Revetta F,Bishop JA

更新日期：2017-09-01 00:00:00

abstract：:Lipomatous lesions of the heart involving the atria and interatrial septum are not well known. Most such lesions do not become clinically significant; however, intractable arrhythmias, blood flow obstruction, and valvular disruption may result from extensive fatty infiltration of the atrial wall or from the mass effec...

journal_title：Human pathology

authors： Cunningham KS,Veinot JP,Feindel CM,Butany J

更新日期：2006-10-01 00:00:00

abstract：:Multifocal/multicentric breast cancers are common. However, investigations of biomarkers such as estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 in individual tumor foci of such cancers are rare. This study was designed to evaluate the status of the hormone receptors, human epide...

journal_title：Human pathology

authors： Choi Y,Kim EJ,Seol H,Lee HE,Jang MJ,Kim SM,Kim JH,Kim SW,Choe G,Park SY

更新日期：2012-01-01 00:00:00

abstract：:Most failures of bioprosthetic heart valves in children are due to stenosis secondary to thrombus, calcific deposits, or tissue ingrowth. Valve failures due to regurgitation typically involve cuspal detachment, tears, or perforations. We present four cases of prosthetic valve regurgitation in children caused by cuspal...

journal_title：Human pathology

authors： Murphy SK,Rogler WC,Fleming WH,McManus BM

更新日期：1988-02-01 00:00:00

abstract：:CD10 is common in B-precursor acute lymphoblastic leukemia (ALL) but is rare in acute myeloid leukemia (AML). However, until recently, analysis for CD10 has generally required fresh or frozen tissue. 56C6 is a monoclonal antibody that is now commercially available for the detection of CD10 in routinely processed paraf...

journal_title：Human pathology

authors： Bavikatty NR,Ross CW,Finn WG,Schnitzer B,Singleton TP

更新日期：2000-09-01 00:00:00

abstract：:Meconium-associated vascular necrosis (MAVN) is a histological abnormality of human placental chorionic vessels that is associated with poor neonatal outcome. We tested the hypothesis that MAVN shows apoptosis in the walls of chorionic vessels. Archival placental specimens with MAVN (n = 5) were compared with specimen...

journal_title：Human pathology

authors： King EL,Redline RW,Smith SD,Kraus FT,Sadovsky Y,Nelson DM

更新日期：2004-04-01 00:00:00

abstract：:Several techniques for diagnosing adenocarcinoma of the lung are commonly available, but the frequency of their use and diagnostic sensitivity may vary. Twenty cases of primary lung adenocarcinoma obtained at surgery were studied by the following four routine techniques: light microscopy (LM) using hematoxylin-eosin (...

journal_title：Human pathology

authors： McGregor DH,Dixon AY,McGregor DK

更新日期：1988-08-01 00:00:00

abstract：:A membrane-bound, Ca2-dependent complex of the cofactor factor Va and the enzyme factor Xa comprises the prothrombinase coagulation complex, which catalyzes the proteolytic conversion of prothrombin to thrombin. In normal hemostasis, the platelet is presumed to supply the surface membrane and thus constitutes the site...

journal_title：Human pathology

authors： Tracy PB,Mann KG

更新日期：1987-02-01 00:00:00

abstract：:Posttransplant lymphoproliferative disorder (PTLD) is associated with Epstein-Barr virus (EBV), and may clinically resemble acute allograft rejection. Three methods to show EBV in tissue were evaluated in 15 liver allograft biopsies from 12 patients including four with PTLD: (1) semiquantitative polymerase chain react...

journal_title：Human pathology

authors： Lones MA,Shintaku IP,Weiss LM,Thung SN,Nichols WS,Geller SA

更新日期：1997-05-01 00:00:00

abstract：:Penile carcinoma (PC) is more frequent in underdeveloped countries, generally is diagnosed at an advanced stage when therapeutic options are restricted, and thus is associated with high morbidity/mortality rates. Recent studies have demonstrated clinical benefits with epidermal growth factor receptor (EGFR)-targeted t...

journal_title：Human pathology

authors： Silva Amancio AM,Cunha IW,Neves JI,Quetz JD,Carraro DM,Rocha RM,Zequi SC,Cubilla AL,da Fonseca FP,Lopes A,Cunha MD,Lima MV,Vassallo J,Guimarães GC,Soares FA

更新日期：2017-03-01 00:00:00

abstract：:Twenty-one cases were selected from 236 thyroidectomies with a diagnosis of Hashimoto's disease for detailed clinicopathologic study on the basis of "early" changes in three cases and an unusually heavy lymphoplasmacytic infiltrate in 18 cases. These cases were studied in conjunction with ten cases of high-grade non-H...

journal_title：Human pathology

authors： Hyjek E,Isaacson PG

更新日期：1988-11-01 00:00:00