Expression and cellular localization of vascular endothelial growth factor A and its receptors in acute and chronic leukemias: an immunohistochemical study.

abstract：:Combined small cell and non-small cell carcinoma is relatively rare in the lung. Examination of the clonal relationship of different components in this type of tumor may give a clue to the rarity. We retrieved 6 such tumors; all 6 had small cell carcinoma and adenocarcinoma components, and 3 had an additional squamous...

journal_title：Human pathology

authors： Murase T,Takino H,Shimizu S,Inagaki H,Tateyama H,Takahashi E,Matsuda H,Eimoto T

更新日期：2003-11-01 00:00:00

abstract：:A case of clear cell sarcoma of tendons and aponeuroses arising in the elbow of a young woman is reported. Local recurrence and lymph node metastases occurred despite radiation therapy, chemotherapy, and amputation of the right arm, and the patient died of the tumor approximately ten months after the initial diagnosis...

journal_title：Human pathology

authors： Azumi N,Turner RR

更新日期：1983-12-01 00:00:00

abstract：:The previously unreported association of granulomatous gastritis and mononeuritis multiplex occurring in the setting of a vasculitic syndrome is described. The two conditions are considered to be associated and to be immune mediated. The previously accepted concept of isolated granulomatous gastritis is disputed. ...

journal_title：Human pathology

authors： O'Donovan C,Murray J,Staunton H,Doyle JS,Leader M

更新日期：1991-10-01 00:00:00

abstract：:Malignant mixed tumors of the parotid gland are rare. Metastasizing lesions are even more rare. To the best of our knowledge, this is the first case reported in the English literature in which the scalp nodule was the primary manifestation of the malignant nature of the parotid tumor. ...

journal_title：Human pathology

authors： Giltman L,Alderete M,Minkowitz S

更新日期：1977-11-01 00:00:00

abstract：:Nonsteroidal anti-inflammatory drug (NSAID) use is a common cause of peptic ulcer. This study investigated the nature, frequency, and topographic distribution of histological abnormalities of the gastric mucosa associated with chronic NSAID use. A set of 3 to 11 mapped gastric biopsy specimens were obtained from 108 c...

journal_title：Human pathology

authors： El-Zimaity HM,Genta RM,Graham DY

更新日期：1996-12-01 00:00:00

abstract：:Gastrointestinal stromal tumor (GIST) is the preferred term for mesenchymal tumors specific for the gastrointestinal tract (60% in stomach, 30% small intestine, 10% elsewhere). GISTs include most tumors previously designated as leiomyoma, cellular leiomyoma, leiomyoblastoma, and leiomyosarcoma. However, in the esophag...

journal_title：Human pathology

authors： Miettinen M,Sarlomo-Rikala M,Lasota J

更新日期：1999-10-01 00:00:00

abstract：:Wild type p53 plays a crucial role in maintaining genomic stability in both normal and tumor cells in vitro. When DNA damage occurs, p53 acts as a cell cycle checkpoint and induces a cellular response that aims at restoring genomic integrity. p53 may either allow the repair of damaged DNA by inducing a transient G1 ar...

journal_title：Human pathology

authors： Moll UM,Ostermeyer AG,Ahomadegbe JC,Mathieu MC,Riou G

更新日期：1995-12-01 00:00:00

abstract：:Mucoepidermoid carcinoma is a common salivary gland malignancy characterized by genetic heterogeneity as well as cellular diversity of its neoplastic components, which include mucinous cells, epidermoid cells and intermediate cells. The clonal and genetic relationship between each component has not been investigated b...

journal_title：Human pathology

authors： Wang W,Zou B,Zhu H,Bao Y

更新日期：2016-10-01 00:00:00

abstract：:Intrasinusoidal infiltration of bone marrow (BM) may accompany several malignant lymphoproliferative disorders. In small B-cell lymphomas, this pattern is considered specific for splenic marginal zone lymphoma (SMZL) when exclusive or prominent, although it may occur in other subtypes of non-Hodgkin's lymphomas (NHLs)...

journal_title：Human pathology

authors： Schenka AA,Gascoyne RD,Duchayne E,Delsol G,Brousset P

更新日期：2003-08-01 00:00:00

abstract：:Immunofluorescent staining of tissue from a lung tumor detected 12 years after excision of a primary malignant melanoma of the skin was negative for prekeratin and positive for vimentin, indicating that the tumor was not epithelial in origin and excluding carcinoma from the differential diagnosis. Complementary conven...

journal_title：Human pathology

authors： Huszar M,Halkin H,Herczeg E,Bubis J,Geiger B

更新日期：1983-11-01 00:00:00

abstract：:Twelve cases of pure adenoid cystic carcinoma of the breast were reviewed. Patients ranged in age from 34 to 69 years. Seven carcinomas were in the right breast, and five in the left; five of the 12 were located in the central region of the breast, five in the upper outer quadrant, and the two in the upper inner and l...

journal_title：Human pathology

authors： Ro JY,Silva EG,Gallager HS

更新日期：1987-12-01 00:00:00

abstract：:Oral squamous cell carcinoma (OSCC) is the most common oral cancer, and major efforts is being made to identify molecular markers capable to differentiate oral potentially malignant lesions (OPMLs) with indolent course from lesions with aggressive behavior. We undertook a study to evaluate if gain of the human telomer...

journal_title：Human pathology

authors： Dorji T,Monti V,Fellegara G,Gabba S,Grazioli V,Repetti E,Marcialis C,Peluso S,Di Ruzza D,Neri F,Foschini MP

更新日期：2015-09-01 00:00:00

abstract：:Eight cases of primary mesenchymal renal tumor in infants under one year of age were studied. The patients' ages ranged from one day to seven months; all but one were diagnosed within the first three months of life. There were four typical congenital mesoblastic nephromas. Two malignant mesenchymal, one intermediate c...

journal_title：Human pathology

authors： Gonzalez-Crussi F,Sotelo-Avila C,Kidd JM

更新日期：1981-01-01 00:00:00

abstract：:Mucosal addressin cell adhesion molecule 1, expressed on gut endothelial cells, in conjunction with integrin alpha(4)beta(7), expressed on lymphocytes, is critical in lymphocyte homing to the gut. The mucosal addressin cell adhesion molecule 1/integrin alpha(4)beta(7) pathway is involved in the pathogenesis of chronic...

journal_title：Human pathology

authors： Di Sabatino A,Rovedatti L,Rosado MM,Carsetti R,Corazza GR,MacDonald TT

更新日期：2009-05-01 00:00:00

abstract：:Human immunodeficiency virus-associated nephropathy (HI-VAN) is a common form of nephropathy present in HIV-infected individuals that clinically presents with proteinuria that is frequently in the nephrotic range, less often with hematuria, and with a course that may evolve to irreversible azotemia ultimately resultin...

journal_title：Human pathology

authors： Rey L,Viciana A,Ruiz P

更新日期：1995-04-01 00:00:00

abstract：:We report 13 cases of unique polypoid urothelial tumors with inverted growth pattern (PUTIPs) occurring in the proximal ureter and renal pelvis. We describe their morphologic features and further characterize them in regard to TERT promoter mutation status and microsatellite instability. Thirteen cases were identified...

journal_title：Human pathology

authors： Wobker SE,Zhong M,Epstein JI

更新日期：2017-01-01 00:00:00

abstract：:DNA methyltransferase 1, 3a, and 3b affect DNA methylation, and it is thought that they play an important role in the malignant transformation of various cancers. The current study was designed to analyze DNA methyltransferase expression by immunohistochemistry in a series of 94 Tunisian sporadic breast carcinomas. Re...

journal_title：Human pathology

authors： Ben Gacem R,Hachana M,Ziadi S,Ben Abdelkarim S,Hidar S,Trimeche M

更新日期：2012-10-01 00:00:00

abstract：:We herein report an 18-month-old girl who presented with a retroperitoneal mature teratoma that later developed into an endodermal sinus tumor. Her symptoms included an expanding abdominal girth. The serum levels of alpha-fetoprotein were moderately elevated. The excised specimen was a benign mature cystic retroperito...

journal_title：Human pathology

authors： Ohno Y,Kanematsu T

更新日期：1998-10-01 00:00:00

abstract：:Heavy proteinuria after bone marrow transplantation (BMT) is rare. Pathology shows membranous glomerulonephritis (MGN) in most cases. After BMT, focal segmental glomerulosclerosis (FSGS) after resolution of MGN has not been reported. We describe a 13-year-old boy who had matched unrelated donor allogeneic BMT for rela...

journal_title：Human pathology

authors： Chan GS,Chim S,Fan YS,Chan KW

更新日期：2006-12-01 00:00:00

abstract：:We investigated the use of remote video microscopy (telepathology) to assist in the diagnosis of 52 neurosurgical frozen section cases. The TelMed system (Discovery Medical Systems, Overland Park, KS), in which the referring pathologist selects appropriate fields for transmission to the consultant, was used for the st...

journal_title：Human pathology

authors： Becker RL Jr,Specht CS,Jones R,Rueda-Pedraza ME,O'Leary TJ

更新日期：1993-08-01 00:00:00

abstract：:Partial monosomy 13q, a chromosomal alteration originally reported in spindle cell lipoma, has also been documented in a few cases of mammary myofibroblastoma. Subsequently, a monoallelic loss of RB1 and FOXO1, located on 13q14, was identified in some cases of cellular angiofibroma, a benign stromal tumor of the lower...

journal_title：Human pathology

authors： Magro G,Righi A,Casorzo L,Antonietta T,Salvatorelli L,Kacerovská D,Kazakov D,Michal M

更新日期：2012-11-01 00:00:00

abstract：:Acute myeloid leukemia is a heterogeneous group of diseases. Mutations of the isocitrate dehydrogenase (IDH) genes represent a novel class of point mutations in acute myeloid leukemia. These mutations prevent oxidative decarboxylation of isocitrate to α-ketoglutarate and confer novel enzymatic activity, facilitating t...

journal_title：Human pathology

authors： Rakheja D,Konoplev S,Medeiros LJ,Chen W

更新日期：2012-10-01 00:00:00

abstract：:The authors report an unusual case of in situ follicular lymphoma associated with progressive transformation of the germinal centers. The patient was a 74-year-old Chinese woman with sequential lymphadenopathy in the right and left cervical regions over a period of 2 months. The first biopsy revealed in situ follicula...

journal_title：Human pathology

authors： Li JN,Zhang WY,Tang Y,Li GD,Dong DD

更新日期：2012-01-01 00:00:00

abstract：:Telomerase is a ribonucleoprotein enzyme associated with cellular immortality and has been detected in the vast majority of adult tumors. Wilms tumor is a histologically diverse embryonal malignancy of childhood, and the histological features of Wilms tumor and its precursor lesion, the nephrogenic rest, recapitulate ...

journal_title：Human pathology

authors： Yashima K,Maitra A,Timmons CF,Rogers BB,Pinar H,Shay JW,Gazdar AF

更新日期：1998-05-01 00:00:00

abstract：:The drs gene was originally isolated from a rat primary embryo fibroblast cDNA library as a suppressor gene against v-src transformation. We have previously shown that expression of drs mRNA was markedly reduced in a variety of human cancer cell lines, including those of the colon, bladder, and ovary. Furthermore, int...

journal_title：Human pathology

authors： Shimakage M,Takami K,Kodama K,Mano M,Yutsudo M,Inoue H

更新日期：2002-06-01 00:00:00

abstract：:The absence of keratin staining in tumor cells from localized fibrous mesotheliomas in both paraffin-embedded and frozen sections with sensitive peroxidase-antiperoxidase and avidin-biotin techniques is described. In addition ot the absence of staining for whole-stratum corneum keratin proteins, sections were negative...

journal_title：Human pathology

authors： Said JW,Nash G,Banks-Schlegel S,Sassoon AF,Shintaku IP

更新日期：1984-05-01 00:00:00

abstract：:Ten cases of reactive follicular hyperplasia and 31 cases of B-cell non-Hodgkin's malignant lymphoma were studied using multiparameter flow cytometry. A bimodal distribution for HLA-DR expression, but not for surface immunoglobulin or B cell-specific antigens CD19 and CD20, was observed commonly in mixed cell type and...

journal_title：Human pathology

authors： Ratech H

更新日期：1990-12-01 00:00:00

abstract：:Implementation of Grade Groups (GrGrs) has been widely accepted for reporting prostate cancer grade since the 2014 International Society of Urological Pathology consensus meeting. Despite their undisputed value for risk stratification, some GrGr are, a priori, quite heterogeneous in that they contain multiple Gleason ...

journal_title：Human pathology

authors： Acosta AM,Taplin ME,Mata DA,D'Amico AV,Hirsch MS

更新日期：2020-05-01 00:00:00

abstract：:Virus-associated hemophagocytic syndrome (VAHS) is a nonneoplastic, generalized histiocytic proliferation with marked hemophagocytosis associated with a systemic viral infection. Histologic studies of lymph nodes usually show lymphoid depletion and histiocytic proliferation. In this report we describe the case of a pa...

journal_title：Human pathology

authors： Daum GS,Sullivan JL,Ansell J,Mulder C,Woda BA

更新日期：1987-10-01 00:00:00

abstract：:p16INK4a immunohistochemistry (IHC) is widely used to facilitate the diagnosis of human papillomavirus (HPV)-associated cervical precancerous lesions. Although most p16 results are distinctly positive or negative, certain ones are ambiguous: they meet some but not all requirements for the "block-positive" pattern. It ...

journal_title：Human pathology

authors： Liu Y,Alqatari M,Sultan K,Ye F,Gao D,Sigel K,Zhang D,Kalir T

更新日期：2017-08-01 00:00:00