Abstract：
:A 61-year-old woman was admitted to the hospital because of general fatigue. Laboratory examinations showed hyponatremia, plasma hypo-osmolarity, and inappropriate increased concentration of the plasma antidiuretic hormone (ADH) in the presence of concentrated urine. Magnetic resonance imaging revealed a mass lesion in the anterior mediastinum. An extended thymectomy was performed under the diagnosis of thymoma with the syndrome of inappropriate secretion of antidiuretic hormone (SIADH). Histologically the tumor was located in the thymic tissue and was diagnosed as ganglioneuroblastoma. Immunohistochemical studies showed the existence of ADH in the tumor cells. To the knowledge of the authors, this is the first case of ganglioneuroblastoma of the thymus with SIADH.
journal_name
Hum Patholjournal_title
Human pathologyauthors
Asada Y,Marutsuka K,Mitsukawa T,Kuribayashi T,Taniguchi S,Sumiyoshi Adoi
10.1016/s0046-8177(96)90094-5subject
Has Abstractpub_date
1996-05-01 00:00:00pages
506-9issue
5eissn
0046-8177issn
1532-8392pii
S0046-8177(96)90094-5journal_volume
27pub_type
杂志文章相关文献
HUMAN PATHOLOGY文献大全abstract：:Mammary analogue secretory carcinoma (MASC) is a recently described salivary gland tumor that has morphologic features similar to secretory carcinoma of the breast and that also harbors the same ETV6 translocation. Diffuse mammaglobin and S-100 immunoreactivity are used to differentiate MASC from its morphologic mimic...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2013.06.010
更新日期：2013-11-01 00:00:00
abstract：:Benign chondroblastoma is an unusual solitary bone tumor occurring usually in the second decade in a long bone. The tumor is often sited on epiphyseal cartilages. Very few examples of malignant variants have been documented, although local recurrence of benign tumors is not unusual. We wish to report a patient who dev...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(80)80014-1
更新日期：1980-05-01 00:00:00
abstract：:Analogous to mixed tumors of salivary glands (" pleomorphic adenomas" ), cutaneous mixed tumors (" chondroid syringomas" ) contain a ductal (epithelial) component and a variably prominent myoepithelial component. Tumors showing purely myoepithelial differentiation (myoepitheliomas) have only recently been recognized t...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2003.08.016
更新日期：2004-01-01 00:00:00
abstract：:Peritoneal involvement in colorectal cancer (CRC) has prognostic significance and is an important parameter in pathologic tumor staging. Restaging of tumors based on peritoneal elastic lamina invasion (ELI) has prognostic significance in CRCs classified as pathologic stage 3 tumors without regional lymph node metastas...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2018.10.019
更新日期：2019-03-01 00:00:00
abstract：:Autopsy studies of three premature siblings who died soon after birth with the neonatal myotonic dystrophy syndrome revealed pulmonary hypoplasia and congenital pleural effusions. Neither of these findings has been described previously in this condition. New ultrastructural findings include focal diaphragmatic myofibe...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(84)80312-3
更新日期：1984-12-01 00:00:00
abstract：:The histologic findings in lymph nodes were used to identify eight patients, who are not in a high-risk group, with human immunodeficiency virus (HIV) infection. In order to determine the specificity of these findings, the histologic and clinical findings in these patients were compared with the histologic and clinica...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(88)80269-7
更新日期：1988-07-01 00:00:00
abstract：:Cystic hygroma of the neck was observed in seven spontaneously aborted, severely autolyzed female fetuses. Four of five karyotyped cases had the 45,XO karyotype; one was a normal female, 46,XX. Diagnostic features associated with monosomy X in fetuses, which were observed in six of these cases, include large cystic hy...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(84)80331-7
更新日期：1984-01-01 00:00:00
abstract：:A case of mucin-positive giant cell carcinoma of the pancreas is presented. Clear cells were a prominent feature of the primary tumor and constituted the majority of the metastatic deposits, a finding not usually associated with pancreatic carcinoma. Results of ultrastructural and histochemical studies are presented, ...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(82)80099-3
更新日期：1982-11-01 00:00:00
abstract：:Cardiac myxoma is the most common primary tumor of the heart. A detailed evaluation of cell types in 41 cardiac myxomas by light microscopy and in 30 cases by immunohistochemistry was made. Reactivity to the various antisera were observed in the surface lining cells, the stromal myxoma cells and the cells in the periv...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(96)90283-x
更新日期：1996-10-01 00:00:00
abstract：:Most esophageal intraepithelial lymphocytes (IELs) express T-cell markers. Increased numbers of esophageal IELs have been shown in reflux esophagitis. The cytotoxic potential and activity of esophageal IELs have not as yet been examined. Our objectives were to determine whether esophageal IELs express the recently des...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(99)90114-4
更新日期：1999-04-01 00:00:00
abstract：:Twelve cases of fibrolamellar hepatocellular carcinoma (FLC) were evaluated for DNA ploidy by means of image analysis of Feulgen-stained tissue sections. All of the tumors showed a nondiploid DNA distribution (six aneuploid and six tetraploid); no diploid pattern was found. The nuclear area of the tumors (53.8 microns...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/0046-8177(94)90015-9
更新日期：1994-09-01 00:00:00
abstract：:Sessile serrated adenomas and traditional serrated adenomas are pathogenetically related to inhibition of apoptosis. Survivin and hedgehog proteins, including sonic hedgehog, patched, and smoothened, inhibit apoptosis, with hedgehog proteins forming a signal transduction cascade implicated in digestive cancers. This s...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2006.12.004
更新日期：2007-05-01 00:00:00
abstract：:Gene hypomethylation and hypermethylation can lead to a loss of genetic imprinting in malignancies. The mechanism responsible for overexpression of the imprinted insulin-like growth factor II (IGF2) gene has not been investigated in osteosarcoma. In this study, the expression levels, imprinting status, and the extent ...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2009.03.003
更新日期：2009-10-01 00:00:00
abstract：:The evolution of sequential histological changes from normal cells through invasive cancer affords the cancer biologist the opportunity to identify separate molecular steps involved in cancer progression. As one studies the development of human carcinoma, it becomes apparent that multiple genetic alterations affecting...
journal_title：Human pathology
pub_type： 杂志文章,评审
doi：10.1016/0046-8177(94)90056-6
更新日期：1994-10-01 00:00:00
abstract：:Cardiac troponin T (cTnT) is considered as a specific marker for acute myocardial infarction. Here, we present a case with elevated cTnT, determined by a third-generation assay, without signs of a myocardial lesion. Routine investigation of a 66-year-old female patient with indolent B-cell lymphoma revealed increased ...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2005.06.009
更新日期：2005-08-01 00:00:00
abstract：:Immunoreactivity to LN2 and LN3, monoclonal antibodies that recognize components of the class II major histocompatibility complex, was assessed in 72 cases of non-small cell lung carcinoma (NSCLC) (32 biopsy specimens, 40 resection specimens) and 64 cases of small cell carcinoma (56 biopsy specimens, 8 resections) of ...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(98)90013-2
更新日期：1998-12-01 00:00:00
abstract：:A case of a primary carcinoid islet cell tumor of the duodenum is reported, demonstrated by histochemistry, electron microscopy, and immunofluorescence to be composed of alpha cells containing glucagon-like material. The patient was found on admission to have hyperglycemia and a diffuse skin rash. Primary duodenal glu...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(79)80032-5
更新日期：1979-05-01 00:00:00
abstract：:Supratentorial primitive neuroectodermal tumors (SPNETs) and medulloblastomas (MBs) are histologically similar intracranial tumors found in different anatomic locations of the brain. Our group has previously demonstrated that loss of chromosome 8p is a frequent event in MBs. The aim of this study was to evaluate wheth...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2004.09.021
更新日期：2005-01-01 00:00:00
abstract：:Primary colorectal diffuse large B-cell lymphoma (DLBCL) is rare, and its clinicopathological and genetic features are poorly understood. The aim of our study was to elucidate the frequency and prognostic significance of molecular subgroups in colorectal DLBCL. We examined 25 cases of colorectal lymphoma with DLBCL-li...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2019.09.003
更新日期：2020-02-01 00:00:00
abstract：:Two extraskeletal myxoid chondrosarcomas were examined by electron microscopy. In addition to the well-described ultrastructural features indicative of chondroblastic origin, both of these chondrosarcomas had unusual parallel microtubules packed within rough endoplasmic reticulum. This paper reviews the differential d...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(86)80036-3
更新日期：1986-05-01 00:00:00
abstract：:Two patients, 14 and 46 years of age, presented with diffuse, rapidly growing intracerebral tumors leading to death 6 1/2 and 9 1/2 months, respectively, after diagnosis. Histological examination showed sheets of moderate-sized tumor cells with clear cytoplasm and central nuclei interrupted by delicate arciform vascul...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/0046-8177(94)90242-9
更新日期：1994-08-01 00:00:00
abstract：:One hundred cases of invasive breast carcinoma were studied using the commercially available monoclonal antibody Anti-Human Tumor-Associated Glycoprotein-72 (MAb B72.3, Biomedical Technologies Inc, Stoughton, MA) prediluted at 8.5 micrograms/mL. Forty-three cases displayed positive reactivity with this antibody. Inten...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/0046-8177(91)90238-k
更新日期：1991-06-01 00:00:00
abstract：:Cancer cells show a higher rate of anaerobic respiration than normal cells. The exact mechanisms for this higher glycolysis rate in cancer cells remain to be elucidated. The results of recent studies have indicated that p53, the most commonly mutated tumor suppressor gene, may have important functions in the regulatio...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2011.04.021
更新日期：2012-02-01 00:00:00
abstract：:The aim of this study was to examine the relation between cofilin 1 expression and progression-free survival in advanced epithelial ovarian cancer. We performed quantitative reverse transcriptase polymerase chain reaction and immunohistochemical analysis in 78 patients with advanced epithelial ovarian cancer (excludin...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2010.07.019
更新日期：2011-04-01 00:00:00
abstract：:We introduce a novel hybrid telepathology system providing simultaneous transmission of both real-time microscopy and static imagery at a reasonable cost. It is capable of capturing static, true color images at resolution of 1,520 x 1,144 pixels and providing live transmission of real-time video images of the glass sl...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1053/hupa.2000.9196
更新日期：2000-07-01 00:00:00
abstract：:Thirty-nine mammographically detected, (M-detected) small invasive carcinomas of the breast (< or = 5 mm) were compared with 78 consecutive clinical cancers (> or = 10 mm) for a variety of morphological and biological markers of prognostic importance. There were more tubular carcinomas in the M-detected group (12.8% v...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(96)90222-1
更新日期：1996-09-01 00:00:00
abstract：:Brain metastases (BMs) are common complications of adenocarcinomas (ADCs) of the lung and are associated with a poor prognosis. Although an increasing amount of data indicates that dysregulated activity of mammalian target of rapamycin (mTOR) can influence the metastatic potential of various tumors, the role of mTOR c...
journal_title：Human pathology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.humpath.2016.12.012
更新日期：2017-04-01 00:00:00
abstract：:Tumor budding (TB) in colorectal carcinoma (CRC) is related to epithelial-mesenchymal transition and has been recently characterized as an indicator of poor prognosis along with lymphovascular tumor emboli, perineural invasion, and an infiltrative growth pattern. Mutations in the genes of the Ras-mitogen-activated pro...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/j.humpath.2017.01.010
更新日期：2017-07-01 00:00:00
abstract：:A mixed gangliocytoma-adenoma occurring in the pituitary fossa of a patient who presented with acromegaly, galactorrhea, and headaches is described. Immunohistochemical studies demonstrated the gangliocytic portion of the tumor to be composed nearly entirely of ganglion cells enmeshed in their neuritic processes and d...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(89)80012-7
更新日期：1989-12-01 00:00:00
abstract：:This article reviews 281 malignant germ cell tumors of the ovary from the Armed Forces Institute of Pathology and highlights their distinctive clinical and pathologic features. Emphasis is placed on the importance of a combined therapeutic approach utilizing surgery, chemotherapy, and radiation. The rationale for unil...
journal_title：Human pathology
pub_type： 杂志文章
doi：10.1016/s0046-8177(77)80115-9
更新日期：1977-09-01 00:00:00
