Multifocal benign chondroblastomas: report of a case.

abstract：:Seven cases in which interstitial fibrosis developed in patients who had acute interstitial pneumonia were studied ultrastructurally to elucidate the pathogenesis of the interstitial thickening seen by light microscopy. Interstitial fibrosis is generally thought to result from fibroblast proliferation and collagen dep...

journal_title：Human pathology

authors： Katzenstein AL

更新日期：1985-10-01 00:00:00

abstract：:Invasive mammary carcinoma with neuroendocrine differentiation has been controversial in terms of its definition and clinical outcome. In 2003, the World Health Organization histologic classification of tumors designated this entity as neuroendocrine carcinoma of the breast and defined mammary neuroendocrine carcinoma...

journal_title：Human pathology

authors： Tian Z,Wei B,Tang F,Wei W,Gilcrease MZ,Huo L,Albarracin CT,Resetkova E,Middleton L,Sahin A,Xing Y,Hunt KK,Chen J,Bu H,Rashid A,Abraham SC,Wu Y

更新日期：2011-08-01 00:00:00

abstract：:Literature on BRCA1-associated protein 1 (BAP1) expression status in well-differentiated papillary mesothelioma (WDPM) is limited. In the present study, we examined the prevalence of BAP1 loss in WDPM by immunohistochemistry with clinical correlation, along with CDKN2A deletion status by fluorescence in situ hybridiza...

journal_title：Human pathology

authors： Lee HE,Molina JR,Sukov WR,Roden AC,Yi ES

更新日期：2018-09-01 00:00:00

abstract：:Syndecan-1, a cell-surface transmembrane heparan sulfate proteoglycan, has been reported to correlate with the biologic behavior of malignant tumors in various organs. We examined the correlation between the expression of syndecan-1 at the protein and mRNA levels and clinicopathologic features of 37 intrahepatic chola...

journal_title：Human pathology

authors： Harada K,Masuda S,Hirano M,Nakanuma Y

更新日期：2003-09-01 00:00:00

abstract：:Perineural invasion is a histologic feature usually diagnostic of invasion in malignancies. In the breast, however, it has been associated with benign lesions such as sclerosing adenosis (SA), complex sclerosing lesion/radial scar (CSL/RS), and ductal carcinoma in situ (DCIS). This article describes perineural invasio...

journal_title：Human pathology

authors： Gobbi H,Jensen RA,Simpson JF,Olson SJ,Page DL

更新日期：2001-08-01 00:00:00

abstract：:Recent evidence has invoked immunohistochemical expression of p63 in Merkel cell carcinoma as an adverse prognostic factor. Conflicting data led us to evaluate this. An Eastern Canadian cohort diagnosed between 1990 and 2012 was studied. Demographic and clinical data were obtained from pathology records and Provincial...

journal_title：Human pathology

authors： Fleming KE,Ly TY,Pasternak S,Godlewski M,Doucette S,Walsh NM

更新日期：2014-05-01 00:00:00

abstract：:Botryomycosis is a rare bacterial infection of the skin and, rarely, viscera that is characterized by the formation of characteristic hyaline grains. We encountered a patient with Erysipelothrix rhusiopathiae endocarditis who developed visceral botryomycosis. He was a 54-year-old black man who presented in sepsis with...

journal_title：Human pathology

authors： Carson HJ,Perkins JT

更新日期：2005-01-01 00:00:00

abstract：:Basal cells of benign prostate glands are typically p63 positive, whereas malignant glands are usually p63 negative. A rare subset of prostatic adenocarcinoma (PCa) demonstrates aberrant diffuse p63 expression but is negative for high-molecular-weight cytokeratin. Strong p63 staining of the tumor cells can obscure the...

journal_title：Human pathology

authors： Uchida K,Ross H,Lotan T,Pignon JC,Signoretti S,Epstein JI,Illei PB

更新日期：2015-03-01 00:00:00

abstract：:An immunohistochemical survey of X-linked inhibitor of apoptosis (XIAP) expression in mammary carcinoma was performed. XIAP, the most potent of the inhibitor of apoptosis family of caspase inhibitors, has been linked to tumor aggressiveness and therapeutic resistance in several malignancies and is considered an attrac...

journal_title：Human pathology

authors： Jaffer S,Orta L,Sunkara S,Sabo E,Burstein DE

更新日期：2007-06-01 00:00:00

abstract：:This study reports clinicopathologic and biological analysis of 45 stage IVS neuroblastomas (IVS-NBs). All IVS-NB cases had small or undetectable primary tumors associated with disease involving the liver, skin, or bone marrow. Their ages at diagnosis ranged from 1 day to 12 months, with a median age of 4 months. The ...

journal_title：Human pathology

authors： Hachitanda Y,Hata J

更新日期：1996-11-01 00:00:00

abstract：:To ensure appropriate mission-based budgeting and equitable distribution of funds for faculty salaries, our compensation committee developed a pathology-specific effort reporting database. Principles included the following: (1) measurement should be done by web-based databases; (2) most entry should be done by departm...

journal_title：Human pathology

authors： Dee FR,Haugen TH,Wynn PA,Leaven TC,Kemp JD,Cohen MB

更新日期：2008-04-01 00:00:00

abstract：:Altered expression of oncogenes and tumor suppressor genes, the normal function of which is to regulate cell growth and differentiation, represents a central event in the pathogenesis of human cancer. Aberrant expression of these genes is often a result of a mutational event. In vitro amplification of DNA with the pol...

journal_title：Human pathology

authors： Loda M

更新日期：1994-06-01 00:00:00

abstract：:Epithelial inclusions in the axillary lymph nodes are very rare and have even less commonly been reported with either benign or malignant changes. We present a case of synchronous high-grade micropapillary ductal carcinoma in situ arising in the breast and in an epithelial inclusion in an ipsilateral sentinel lymph no...

journal_title：Human pathology

authors： Fitzpatrick-Swallow VL,Helin H,Cane P,Pinder SE

更新日期：2013-01-01 00:00:00

abstract：:Partial monosomy 13q, a chromosomal alteration originally reported in spindle cell lipoma, has also been documented in a few cases of mammary myofibroblastoma. Subsequently, a monoallelic loss of RB1 and FOXO1, located on 13q14, was identified in some cases of cellular angiofibroma, a benign stromal tumor of the lower...

journal_title：Human pathology

authors： Magro G,Righi A,Casorzo L,Antonietta T,Salvatorelli L,Kacerovská D,Kazakov D,Michal M

更新日期：2012-11-01 00:00:00

abstract：:Focal apocrine metaplasia was studied in 293 whole human breasts by a subgross sampling technique with histologic confirmation. There were 186 breasts obtained from random autopsies. Another 107 breasts were obtained that were cancer-associated; these breasts either contained an invasive cancer or were situated contra...

journal_title：Human pathology

authors： Wellings SR,Alpers CE

更新日期：1987-04-01 00:00:00

abstract：:Although the term "thyroiditis" suggests inflammation, many disorders of the thyroid that are of unknown etiology are also currently included under this heading. Thus, only infective thyroiditis and subacute thyroiditis are clearly inflammatory; autoimmune thyroiditis is a result of lymphocytic and fibroblastic infilt...

journal_title：Human pathology

authors： Volpé R

更新日期：1978-07-01 00:00:00

abstract：:To elucidate the role of Epstein-Barr virus (EBV) in salivary gland carcinomas, 56 cases of carcinomas of major salivary glands were investigated. These included 14 mucoepidermoid carcinomas, 13 adenoid cystic carcinomas, seven malignant mixed tumors, four adenocarcinomas, four salivary duct carcinomas, two acinic cel...

journal_title：Human pathology

authors： Tsai CC,Chen CL,Hsu HC

更新日期：1996-03-01 00:00:00

abstract：:To assess the epileptogenic lesions, a series of 202 cases with temporal lobectomy were analyzed histopathologically. The severity of hippocampal neuronal loss in patients with temporal lobe epilepsy was quantitatively analyzed and compared against autopsy controls of patients who died of nonneurologic disorders. For ...

journal_title：Human pathology

authors： Lee MC,Kim GM,Woo YJ,Kim MK,Kim JH,Nam SC,Suh JJ,Chung WK,Lee JS,Kim HI,Choi HY,Kim SU

更新日期：2001-06-01 00:00:00

abstract：:Promyelocytic leukemia zinc finger is a zinc finger transcription factor that functions as a transcriptional repressor. Its expression has been shown to be down-regulated in hematopoietic, melanocytic, and mesothelial malignancies. Histone H1.5 is a variant of histone H1, a family of linker proteins that organizes chr...

journal_title：Human pathology

authors： Hechtman JF,Beasley MB,Kinoshita Y,Ko HM,Hao K,Burstein DE

更新日期：2013-07-01 00:00:00

abstract：:Four cases of radiation cystitis that caused diagnostic difficulty because of an epithelial proliferation with architectural complexity and reactive cytologic atypia are described. The patients, 2 male, 2 female, were from 43 to 77 years of age. Two presented with hematuria. Cystoscopy disclosed abnormalities in 3 pat...

journal_title：Human pathology

authors： Baker PM,Young RH

更新日期：2000-06-01 00:00:00

abstract：:Four monoclonal antibodies (MoAbs), 60.15, 61.3, 105.10, and 2.16, directed to different proteins of Mycobacterium tuberculosis were used by an indirect avidin-biotin complex peroxidase-antiperoxidase method to detect mycobacterial antigens in lung, lymph node, and joint tissue specimens of tuberculous patients. Using...

journal_title：Human pathology

authors： Barbolini G,Bisetti A,Colizzi V,Damiani G,Migaldi M,Vismara D

更新日期：1989-11-01 00:00:00

abstract：:In general, the large cell lymphomas are a cytogenetically heterogeneous group of diseases, and the cytogenetic findings do not correlate with morphological findings in this group of malignant lymphomas. The CD30-positive anaplastic large cell lymphomas, however, are thought to be an exception, with the t(2;5) reporte...

journal_title：Human pathology

authors： Arber DA,Sun LH,Weiss LM

更新日期：1996-06-01 00:00:00

abstract：:In two patients with malignant germ cell tumors angiosarcoma developed through two apparently different mechanisms. In one case the angiosarcoma probably developed as a complication of therapeutic radiation, since radiation changes were demonstrated in tissue adjacent to the neoplasm and since the angiosarcoma was not...

journal_title：Human pathology

authors： Ulbright TM,Clark SA,Einhorn LH

更新日期：1985-03-01 00:00:00

abstract：:Clinicopathological and cytogenetic studies were performed on specimens from 43 patients with CD30-positive anaplastic large cell lymphoma (ALCL). All patients were born and lived in a human T-cell lymphotropic virus (HTLV)-I endemic area. Twenty-one patients (48.8%) had serum anti-HTLV-I antibody suggesting the prese...

journal_title：Human pathology

authors： Takeshita M,Ohshima K,Akamatsu M,Ohgami A,Kikuchi M,Suzumiya J,Uike N,Okamura T,Nakayama J

更新日期：1995-06-01 00:00:00

abstract：:Glucose transporter (GLUT)-1 is expressed in malignant tumors and correlated with poor outcome in several cancers. Biliary intraepithelial neoplasia (BilIN) is considered to be a precursor or a noninvasive lesion of invasive cholangiocarcinoma. We examined GLUT-1 and GLUT-2 expression in 149 intrahepatic cholangiocarc...

journal_title：Human pathology

authors： Kubo Y,Aishima S,Tanaka Y,Shindo K,Mizuuchi Y,Abe K,Shirabe K,Maehara Y,Honda H,Oda Y

更新日期：2014-08-01 00:00:00

abstract：:Mammary analogue secretory carcinoma (MASC) is a recently described salivary gland tumor that has morphologic features similar to secretory carcinoma of the breast and that also harbors the same ETV6 translocation. Diffuse mammaglobin and S-100 immunoreactivity are used to differentiate MASC from its morphologic mimic...

journal_title：Human pathology

authors： Patel KR,Solomon IH,El-Mofty SK,Lewis JS Jr,Chernock RD

更新日期：2013-11-01 00:00:00

abstract：:The spectrum of neuroendocrine (NE) tumors in the genitourinary tract ranges from the aggressive large and small cell carcinomas to the often benign paraganglioma and well-differentiated neuroendocrine tumor (WD-NET). At least 15 pure lower urinary tract (LUT) WD-NETs have been described. Owing to the rarity of WD-NET...

journal_title：Human pathology

authors： Rodriguez Pena MDC,Salles DC,Epstein JI,Canete-Portillo S,Tregnago AC,Ramirez J,Meliti A,Netto GJ

更新日期：2020-12-08 00:00:00

abstract：:Glypican 3 is a heparin sulfate proteoglycan bound to the cell surface that is theorized to participate in cell signaling, resulting in embryonic cell growth and differentiation. The GPC3 gene is mutated in Simpson-Golabi-Behmel syndrome, whose features include numerous developmental abnormalities, tissue overgrowth, ...

journal_title：Human pathology

authors： Zynger DL,Gupta A,Luan C,Chou PM,Yang GY,Yang XJ

更新日期：2008-02-01 00:00:00

abstract：:Epidermal growth factor receptor is a transmembrane receptor involved in oncogenesis, including the development of glioblastoma. We studied the prognostic significance of epidermal growth factor receptor amplification as determined by fluorescence in situ hybridization, quantitative polymerase chain reaction, and prot...

journal_title：Human pathology

authors： Coulibaly B,Nanni I,Quilichini B,Gaudart J,Metellus P,Fina F,Boucard C,Chinot O,Ouafik L,Figarella-Branger D

更新日期：2010-06-01 00:00:00

abstract：:Ovarian cancer, consisting predominantly of ovarian carcinoma, is the eighth most common cancer in women and the most lethal gynecologic malignancy. Efforts focus on identifying biomarkers which may aid in early diagnosis and reduce mortality, as well as on characterizing therapeutic targets with the aim of circumvent...

journal_title：Human pathology

authors： Katz B,Tropé CG,Reich R,Davidson B

更新日期：2015-09-01 00:00:00