Genetic and environmental influences on depressive symptoms in Chinese adolescents.

Abstract:

:Adolescent depression is common and has become a major public health concern in China, yet little research has examined the etiology of depression in Chinese adolescents. In the present study, genetic and environmental influences on Chinese adolescent depressive symptoms were investigated in 1,181 twin pairs residing in Beijing, China (ages 11-19 years). Child- and parent-versions of the children's depression inventory were used to measure adolescents' depressive symptoms. For self-reports, genetic factors, shared environmental factors, and non-shared environmental factors accounted for 50, 5, and 45 % of the variation in depressive symptoms, respectively; for parent-reports, genetic factors, shared environmental factors, and non-shared environmental factors accounted for 51, 18, and 31 % of the variation, respectively. These estimates are generally consistent with previous findings in Western adolescents, supporting the cross-cultural generalizability of etiological model of adolescent depression. Neither qualitative nor quantitative sex differences were found in the etiological model. Future studies are needed to investigate how genes and environments work together (gene-environment interaction, gene-environment correlation) to influence depression in Chinese adolescents.

journal_name

Behav Genet

journal_title

Behavior genetics

authors

Chen J,Li X,Natsuaki MN,Leve LD,Harold GT

doi

10.1007/s10519-013-9632-8

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

36-44

issue

1

eissn

0001-8244

issn

1573-3297

journal_volume

44

pub_type

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